The network for 'regulation of mesodermal cell fate specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mesodermal cell fate specification

Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.

NameDescriptionProbabilityFunc Analog Organism
ventventral expressed homeobox0.866
gli1GLI-Kruppel family member 10.846
fgfr1afibroblast growth factor receptor 1a0.779
bmp4bone morphogenetic protein 40.724
tbx1T-box 10.709
chdchordin0.630
tbx16T-box gene 160.563
foxi1forkhead box I10.561
msxcmuscle segment homeobox C0.463
hnf1baHNF1 homeobox Ba0.461
eya1eyes absent homolog 10.382
pax2apaired box gene 2a0.366
voxventral homeobox0.345
sox10SRY-box containing gene 100.321
her7hairy and enhancer of split related-70.317
tbx6T-box gene 60.313
bmp2bbone morphogenetic protein 2b0.309
metmet proto-oncogene (hepatocyte growth factor receptor)0.258
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.251
pcdh8protocadherin 80.237
eve1even-skipped-like10.236
fgf3fibroblast growth factor 30.225
hoxd4ahomeo box D4a0.224
nkd1naked cuticle homolog 1 (Drosophila)0.205
foxn4forkhead box N40.198
flhfloating head0.191
hmx4H6 family homeobox 40.186
fgf10afibroblast growth factor 10a0.181
msxemuscle segment homeobox E0.178
bmp7abone morphogenetic protein 7a0.176
foxd5forkhead box D50.174
wnt4awingless-type MMTV integration site family, member 4a0.171
vsx2visual system homeobox 20.170
pax8paired box gene 80.168
neurod4neurogenic differentiation 40.165
wnt5bwingless-type MMTV integration site family, member 5b0.159
foxb1.2forkhead box B1.20.153
dharmadharma0.148
cdx4caudal type homeo box transcription factor 40.146
sox9bSRY-box containing gene 9b0.139
nkx2.2aNK2 transcription factor related 2a0.136
wnt9awingless-type MMTV integration site family, member 9A0.120
brd4bromodomain containing 40.112
irf6interferon regulatory factor 60.111
mibmind bomb0.109
tal1T-cell acute lymphocytic leukemia 10.107
hoxc6ahomeo box C6a0.107
vedventrally expressed dharma/bozozok antagonist0.104
tbx20T-box 200.103
admpanti-dorsalizing morphogenic protein0.102
hoxb4ahomeo box B4a0.097
hoxb2ahomeo box B2a0.095
oepone-eyed pinhead0.091
tll1tolloid-like 10.090
evx1even-skipped homeobox 10.090
wnt8bwingless-type MMTV integration site family, member 8b0.086
hoxa2bhomeo box A2b0.085
lmx1b.1LIM homeobox transcription factor 1, beta 10.085
dab1adisabled homolog 1a (Drosophila)0.081
spry2sprouty homolog 20.080
efnb3bephrin B3b0.077
ascl1aachaete-scute complex-like 1a (Drosophila)0.074
hoxb8ahomeo box B8a0.074
prickle1aprickle-like 1 (Drosophila) a0.073
tbx2bT-box 2b0.072
sox2SRY-box containing gene 20.070
shhasonic hedgehog a0.068
dlcdeltaC0.068
lef1lymphocyte enhancer binding factor 10.066
vsx1visual system homeobox 1 homolog, chx10-like0.062
wnt1wingless-type MMTV integration site family, member 10.060
dkk1bdickkopf 1b0.059
wnt11wingless-type MMTV integration site family, member 110.055
nrarpbnotch-regulated ankyrin repeat protein b0.055
hoxc4ahomeo box C4a0.053
tbx5aT-box 5a0.051
six1bsine oculis homeobox homolog 1b0.050
wif1wnt inhibitory factor 10.049
gata2aGATA-binding protein 2a0.046
hoxb5bhomeo box B5b0.046
sp7Sp7 transcription factor0.046
sall4sal-like 4 (Drosophila)0.046
her1hairy-related 10.046
tbx18T-box 180.045
gdf6bgrowth differentiation factor 6b0.042
sox32SRY-box containing gene 320.041
vax2ventral anterior homeobox 20.041
spns2spinster homolog 2 (Drosophila)0.040
hoxc8ahomeo box C8a0.040
traf4atnf receptor-associated factor 4a0.040
atoh1aatonal homolog 1a0.040
smosmoothened homolog (Drosophila)0.040
runx2brunt-related transcription factor 2b0.040
epha7eph receptor A70.040
rx2retinal homeobox gene 20.039
dusp6dual specificity phosphatase 60.039
dlx3bdistal-less homeobox gene 3b0.039
notch3notch homolog 30.039
col8a1acollagen, type VIII, alpha 1a0.039
prox1prospero-related homeobox gene 10.038
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BMP2bone morphogenetic protein 20.909
JAG1jagged 10.756
FRS2fibroblast growth factor receptor substrate 20.721
XIAPX-linked inhibitor of apoptosis0.520
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.493
LRP6low density lipoprotein receptor-related protein 60.453
NOTCH3notch 30.369
FZD1frizzled homolog 1 (Drosophila)0.159
MAML1mastermind-like 1 (Drosophila)0.138
FGF2fibroblast growth factor 2 (basic)0.080
NEDD4neural precursor cell expressed, developmentally down-regulated 40.066
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.053
FGF1fibroblast growth factor 1 (acidic)0.045
SMURF1SMAD specific E3 ubiquitin protein ligase 10.044
ATXN1Lataxin 1-like0.042
PLCG1phospholipase C, gamma 10.036
NOTCH2notch 20.028
LATlinker for activation of T cells0.027
JAG2jagged 20.026
DLL1delta-like 1 (Drosophila)0.026
FGFR2fibroblast growth factor receptor 20.021
FZD8frizzled homolog 8 (Drosophila)0.020
IRS1insulin receptor substrate 10.018
SMAD1SMAD family member 10.018
NOSTRINnitric oxide synthase trafficker0.018
MDFIMyoD family inhibitor0.017
SPENspen homolog, transcriptional regulator (Drosophila)0.016
CYR61cysteine-rich, angiogenic inducer, 610.016
BMP4bone morphogenetic protein 40.015
HOXC8homeobox C80.014
EGR1early growth response 10.013
LBX1ladybird homeobox 10.013
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.013
FSTL1follistatin-like 10.013
FGF3fibroblast growth factor 30.012
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.012
FOXE1forkhead box E1 (thyroid transcription factor 2)0.012
WNT6wingless-type MMTV integration site family, member 60.012
PDX1pancreatic and duodenal homeobox 10.011
GATA5GATA binding protein 50.011
F3coagulation factor III (thromboplastin, tissue factor)0.010
GFI1Bgrowth factor independent 1B transcription repressor0.010
FZD2frizzled homolog 2 (Drosophila)0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Shhsonic hedgehog1.000
Pax3paired box gene 31.000
Gli3GLI-Kruppel family member GLI31.000
Bmp4bone morphogenetic protein 41.000
Foxc1forkhead box C11.000
Pax2paired box gene 20.999
Fgf8fibroblast growth factor 80.998
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.998
Eya1eyes absent 1 homolog (Drosophila)0.996
Jag1jagged 10.996
Tbx1T-box 10.995
Foxc2forkhead box C20.994
Fgf10fibroblast growth factor 100.991
Pitx2paired-like homeodomain transcription factor 20.990
Vangl2vang-like 2 (van gogh, Drosophila)0.986
Ctnnb1catenin (cadherin associated protein), beta 10.979
Tcfap2atranscription factor AP-2, alpha0.976
Fgfr1fibroblast growth factor receptor 10.967
Sox9SRY-box containing gene 90.967
Otx2orthodenticle homolog 2 (Drosophila)0.964
Rargretinoic acid receptor, gamma0.947
Isl1ISL1 transcription factor, LIM/homeodomain0.943
Meox2mesenchyme homeobox 20.935
Chd7chromodomain helicase DNA binding protein 70.933
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.932
Hoxa1homeobox A10.930
Wnt3awingless-related MMTV integration site 3A0.916
Tgfb2transforming growth factor, beta 20.897
Acvr1activin A receptor, type 10.891
Gbx2gastrulation brain homeobox 20.886
Prrx1paired related homeobox 10.873
Hand2heart and neural crest derivatives expressed transcript 20.860
Foxg1forkhead box G10.830
Sox2SRY-box containing gene 20.822
Dlx5distal-less homeobox 50.805
Fgfr3fibroblast growth factor receptor 30.789
Pax6paired box gene 60.772
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.757
Smosmoothened homolog (Drosophila)0.756
Sfrp2secreted frizzled-related protein 20.734
Hand1heart and neural crest derivatives expressed transcript 10.721
Apcadenomatosis polyposis coli0.707
Gli2GLI-Kruppel family member GLI20.696
Gata4GATA binding protein 40.695
Hoxd13homeobox D130.678
Zeb1zinc finger E-box binding homeobox 10.678
Vegfavascular endothelial growth factor A0.572
Hes1hairy and enhancer of split 1 (Drosophila)0.545
Nos3nitric oxide synthase 3, endothelial cell0.517
Bmpr1abone morphogenetic protein receptor, type 1A0.514
Hoxa3homeobox A30.512
Efnb2ephrin B20.498
Nognoggin0.494
Rarbretinoic acid receptor, beta0.487
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.478
Msx1homeobox, msh-like 10.450
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.447
Nodalnodal0.440
Psen1presenilin 10.387
Alx4aristaless-like homeobox 40.383
Ednraendothelin receptor type A0.379
Lmx1aLIM homeobox transcription factor 1 alpha0.340
Fgf3fibroblast growth factor 30.333
Hoxa2homeobox A20.313
Hmx3H6 homeobox 30.308
Sox11SRY-box containing gene 110.284
Gata3GATA binding protein 30.274
Dll1delta-like 1 (Drosophila)0.254
Bmp7bone morphogenetic protein 70.254
Rxraretinoid X receptor alpha0.236
Prrx2paired related homeobox 20.231
Rararetinoic acid receptor, alpha0.212
Nf1neurofibromatosis 10.209
Ror2receptor tyrosine kinase-like orphan receptor 20.203
Ptpn11protein tyrosine phosphatase, non-receptor type 110.169
Mesp1mesoderm posterior 10.165
Pbx1pre B-cell leukemia transcription factor 10.163
Pax8paired box gene 80.159
Pitx1paired-like homeodomain transcription factor 10.157
Ece1endothelin converting enzyme 10.156
Lrp6low density lipoprotein receptor-related protein 60.152
Ptenphosphatase and tensin homolog0.140
Smad6MAD homolog 6 (Drosophila)0.139
Retret proto-oncogene0.130
Hspg2perlecan (heparan sulfate proteoglycan 2)0.124
Rb1retinoblastoma 10.123
Ptch1patched homolog 10.122
Gscgoosecoid homeobox0.121
Lmx1bLIM homeobox transcription factor 1 beta0.121
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.117
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.115
Smad4MAD homolog 4 (Drosophila)0.109
Nkx2-1NK2 homeobox 10.106
Cdkn1bcyclin-dependent kinase inhibitor 1B0.104
Twist2twist homolog 2 (Drosophila)0.103
Pou4f3POU domain, class 4, transcription factor 30.087
Bcl6bB-cell CLL/lymphoma 6, member B0.087
Engendoglin0.086
Tcf15transcription factor 150.085
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism