The network for 'negative regulation of neutrophil chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of neutrophil chemotaxis

Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

NameDescriptionProbabilityFunc Analog Organism
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.860
kdrlkinase insert domain receptor like0.579
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.467
cxcr4achemokine (C-X-C motif) receptor 4a0.331
cxcr4bchemokine (C-X-C motif), receptor 4b0.216
btg2B-cell translocation gene 20.134
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.125
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.099
dlcdeltaC0.097
etv2ets variant gene 20.084
dlddeltaD0.075
grhl2bgrainyhead-like 2b (Drosophila)0.069
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.068
dhrs3adehydrogenase/reductase (SDR family) member 3a0.063
fbn2bfibrillin 2b0.062
hhiphedgehog interacting protein0.057
epha4aeph receptor A4a0.054
crip2cysteine-rich protein 20.048
lmo4aLIM domain only 4a0.047
myod1myogenic differentiation 10.042
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.041
aplnrbapelin receptor b0.040
grnagranulin a0.040
pea3ETS-domain transcription factor pea30.038
ptprcprotein tyrosine phosphatase, receptor type, C0.038
sfrp1asecreted frizzled-related protein 1a0.037
bonbonnie and clyde0.036
si:dkeyp-7c9.1si:dkeyp-7c9.10.036
sulf1sulfatase 10.033
lef1lymphocyte enhancer binding factor 10.031
lmo2LIM domain only 2 (rhombotin-like 1)0.030
nkx2.5NK2 transcription factor related 50.030
pdzrn3PDZ domain containing RING finger 3 and PDZ domain containing ring finger 30.029
aplnraapelin receptor a0.029
her6hairy-related 60.028
sox10SRY-box containing gene 100.027
mychmyelocytomatosis oncogene homolog0.026
apoebapolipoprotein Eb0.026
meis1myeloid ecotropic viral integration 10.026
hlx1H2.0-like homeo box 1 (Drosophila)0.026
vsg1vessel-specific 10.025
foxc1bforkhead box C1b0.025
si:dkey-261h17.1si:dkey-261h17.10.024
gmfgglia maturation factor, gamma0.024
bmperBMP binding endothelial regulator0.021
cdh5cadherin 50.021
epha7eph receptor A70.020
hey1hairy/enhancer-of-split related with YRPW motif 10.020
pdgfaaplatelet-derived growth factor alpha a0.020
lrrc33leucine rich repeat containing 330.020
tal1T-cell acute lymphocytic leukemia 10.020
hspa12bheat shock protein 12B0.019
clic4chloride intracellular channel 40.019
spry1sprouty homolog 1 (Drosophila)0.019
prox1prospero-related homeobox gene 10.018
nrarpanotch-regulated ankyrin repeat protein a0.018
kal1bKallmann syndrome 1b sequence0.018
cdh1cadherin 1, epithelial0.017
ntlano tail a0.017
her1hairy-related 10.017
crhcorticotropin releasing hormone0.017
mmp2matrix metalloproteinase 20.017
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.017
cadm1acell adhesion molecule 1a0.016
lfnglunatic fringe homolog0.016
coro1acoronin, actin binding protein, 1A0.016
yrkYes-related kinase0.016
acvrl1activin A receptor type II-like 10.016
gscgoosecoid0.016
lhx9LIM homeobox 90.016
ptmaaprothymosin, alpha a0.016
aldh1a2aldehyde dehydrogenase 1 family, member A20.015
rhogbras homolog gene family, member Gb0.015
ogt.1O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 10.015
flncbfilamin C, gamma b (actin binding protein 280)0.015
kctd12.2potassium channel tetramerisation domain containing 12.20.015
spry4sprouty (Drosophila) homolog 40.014
hmx2H6 family homeobox 20.014
blfbloody fingers0.014
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.013
pcdh18aprotocadherin 18a0.013
kal1aKallmann syndrome 1a sequence0.013
ptpn6protein tyrosine phosphatase, non-receptor type 60.013
lyzlysozyme0.013
dusp5dual specificity phosphatase 50.013
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.012
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.012
efnb2aephrin B2a0.012
gdf6agrowth differentiation factor 6a0.012
pmchpro-melanin concentrating hormone0.012
ptenaphosphatase and tensin homolog A0.011
pak2ap21 (CDKN1A)-activated kinase 2a0.011
mafv-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog0.011
csrp1acysteine and glycine-rich protein 1a0.010
gata1aGATA binding protein 1a0.010
lrrc6leucine rich repeat containing 60.010
mmp9matrix metalloproteinase 90.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.890
DPP4dipeptidyl-peptidase 40.489
DCNdecorin0.391
ATN1atrophin 10.266
COL14A1collagen, type XIV, alpha 10.150
CCR5chemokine (C-C motif) receptor 50.146
PTGISprostaglandin I2 (prostacyclin) synthase0.110
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.062
COL1A2collagen, type I, alpha 20.056
RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.053
SFRP4secreted frizzled-related protein 40.049
POSTNperiostin, osteoblast specific factor0.043
COL3A1collagen, type III, alpha 10.041
GLT8D2glycosyltransferase 8 domain containing 20.038
MFAP4microfibrillar-associated protein 40.035
BAIAP2BAI1-associated protein 20.032
LAMA4laminin, alpha 40.030
MGPmatrix Gla protein0.028
SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A0.025
VCANversican0.024
RBMS3RNA binding motif, single stranded interacting protein 30.023
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.022
CXCL12chemokine (C-X-C motif) ligand 120.021
IGF1insulin-like growth factor 1 (somatomedin C)0.020
MYH11myosin, heavy chain 11, smooth muscle0.020
ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)0.020
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.019
SLIT2slit homolog 2 (Drosophila)0.019
LTBP2latent transforming growth factor beta binding protein 20.019
REREarginine-glutamic acid dipeptide (RE) repeats0.019
MXRA5matrix-remodelling associated 50.019
EFEMP1EGF containing fibulin-like extracellular matrix protein 10.018
LTBP4latent transforming growth factor beta binding protein 40.018
IGFBP5insulin-like growth factor binding protein 50.017
DPTdermatopontin0.017
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif, 50.017
BNC2basonuclin 20.017
CHRDL1chordin-like 10.017
VGLL3vestigial like 3 (Drosophila)0.016
SRPXsushi-repeat containing protein, X-linked0.015
COL6A3collagen, type VI, alpha 30.015
AEBP1AE binding protein 10.015
LDB2LIM domain binding 20.015
FBLN5fibulin 50.015
SPARCL1SPARC-like 1 (hevin)0.015
CCDC80coiled-coil domain containing 800.015
GEMGTP binding protein overexpressed in skeletal muscle0.015
FBLN2fibulin 20.014
OMDosteomodulin0.014
JAM2junctional adhesion molecule 20.014
ECM2extracellular matrix protein 2, female organ and adipocyte specific0.014
GIGYF1GRB10 interacting GYF protein 10.013
SFRP2secreted frizzled-related protein 20.013
SYVN1synovial apoptosis inhibitor 1, synoviolin0.013
LAMA2laminin, alpha 20.013
FLRT2fibronectin leucine rich transmembrane protein 20.012
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.012
C7complement component 70.012
FBN1fibrillin 10.012
FRZBfrizzled-related protein0.012
SFRP1secreted frizzled-related protein 10.012
FMODfibromodulin0.011
MEGF11multiple EGF-like-domains 110.011
ISLRimmunoglobulin superfamily containing leucine-rich repeat0.011
SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.011
CXCL14chemokine (C-X-C motif) ligand 140.011
TGFB3transforming growth factor, beta 30.011
OLFML1olfactomedin-like 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism