The network for 'macromolecule biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

NameDescriptionProbabilityFunc Analog Organism
fgf3fibroblast growth factor 30.995
notch1anotch homolog 1a0.993
gli1GLI-Kruppel family member 10.989
eya1eyes absent homolog 10.988
spry4sprouty (Drosophila) homolog 40.985
ctgfconnective tissue growth factor0.982
smosmoothened homolog (Drosophila)0.982
pcnaproliferating cell nuclear antigen0.978
gata3GATA-binding protein 30.977
rad21RAD21 homolog (S. pombe)0.972
bmp4bone morphogenetic protein 40.970
foxi1forkhead box I10.962
prdm1aPR domain containing 1a, with ZNF domain0.962
tfap2atranscription factor AP-2 alpha0.958
fgfr1afibroblast growth factor receptor 1a0.957
shhasonic hedgehog a0.952
etv5bets variant 5b0.951
runx2brunt-related transcription factor 2b0.949
evx1even-skipped homeobox 10.949
wnt11rwingless-type MMTV integration site family, member 11, related0.946
sox9aSRY-box containing gene 9a0.941
hnf1baHNF1 homeobox Ba0.937
crabp2acellular retinoic acid binding protein 2, a0.937
hoxc4ahomeo box C4a0.929
myod1myogenic differentiation 10.927
dlx5adistal-less homeobox gene 5a0.918
gbx1gastrulation brain homeobox 10.907
six1bsine oculis homeobox homolog 1b0.904
pitx3paired-like homeodomain transcription factor 30.904
neo1neogenin 10.901
ndr2nodal-related 20.892
rx3retinal homeobox gene 30.889
tp53tumor protein p530.880
jag1bjagged 1b0.876
atoh7atonal homolog 70.869
ccnd1cyclin D10.868
pcdh18bprotocadherin 18b0.867
atoh1aatonal homolog 1a0.864
dkk1bdickkopf 1b0.863
myf5myogenic factor 50.858
snai1bsnail homolog 1b (Drosophila)0.853
six3asine oculis homeobox homolog 3a0.849
col2a1acollagen type II, alpha-1a0.846
btg2B-cell translocation gene 20.845
gbx2gastrulation brain homeo box 20.844
barx1BarH-like homeobox 10.833
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.828
bmp2bbone morphogenetic protein 2b0.828
cfl2lcofilin 2, like0.828
irx4biroquois homeobox protein 4b0.825
fgf17fibroblast growth factor 170.817
foxa2forkhead box A20.812
cdx4caudal type homeo box transcription factor 40.804
raraaretinoic acid receptor, alpha a0.804
ret1receptor tyrosine kinase0.803
frem3Fras1 related extracellular matrix 30.803
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.802
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.798
mbnl2muscleblind-like 2 (Drosophila)0.798
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.794
gata6GATA-binding protein 60.788
gpr126G protein-coupled receptor 1260.787
mecomMDS1 and EVI1 complex locus0.779
otpaorthopedia homolog a0.778
rnf2ring finger protein 20.778
fezf2FEZ family zinc finger 20.775
lmx1b.1LIM homeobox transcription factor 1, beta 10.774
arxaristaless related homeobox0.774
fgf10afibroblast growth factor 10a0.769
ihhaIndian hedgehog homolog a0.755
dlx3bdistal-less homeobox gene 3b0.751
vegfaavascular endothelial growth factor Aa0.746
ntlano tail a0.745
maflv-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L0.739
tbx18T-box 180.738
nkx2.3NK2 transcription factor related 30.736
whsc1Wolf-Hirschhorn syndrome candidate 10.734
hand2heart and neural crest derivatives expressed transcript 20.734
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.733
sox19aSRY-box containing gene 19a0.727
setdb1bSET domain, bifurcated 1b0.726
dmrt3adoublesex and mab-3 related transcription factor 3a0.725
lhx1aLIM homeobox 1a0.723
ezh2enhancer of zeste homolog 2 (Drosophila)0.722
pax6apaired box gene 6a0.720
tal1T-cell acute lymphocytic leukemia 10.720
pdlim7PDZ and LIM domain 70.719
top2atopoisomerase (DNA) II alpha0.719
six4asine oculis homeobox homolog 4a0.718
LOC100151531zinc finger protein Gfi-1b-like0.718
fstafollistatin a0.716
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
pha-4Protein PHA-40.986
egl-18Protein EGL-180.984
hlh-2Protein HLH-20.808
vab-3Protein VAB-30.716
D1081.8Protein D1081.80.704
egl-27Protein EGL-270.652
nhr-67Protein NHR-670.650
iff-1Protein IFF-10.639
his-5Protein HIS-50.624
attf-2Protein ATTF-20.594
pqn-59Protein PQN-590.573
rpt-3Protein RPT-30.571
eftu-2Protein EFTU-20.558
unc-62Protein UNC-620.556
rpn-1Protein RPN-10.549
F53F10.2Protein F53F10.20.548
eya-1Protein EYA-10.541
his-31Protein HIS-310.529
lmn-1Protein LMN-10.528
his-64Protein HIS-640.523
pas-4Protein PAS-40.507
dbr-1Protein DBR-10.501
CELE_W03F9.10Protein W03F9.100.498
cam-1Protein CAM-10.497
dlk-1Protein DLK-10.484
ceh-20Protein CEH-200.483
his-50Protein HIS-500.461
his-52Protein HIS-520.455
zip-7Protein ZIP-70.448
rsa-2Protein RSA-20.434
ifg-1Protein IFG-10.432
csn-4Protein CSN-40.426
lin-36Protein LIN-360.422
npp-7Protein NPP-70.418
his-46Protein HIS-460.415
fkh-2Protein FKH-20.413
F36D4.5Protein F36D4.50.408
his-1Protein HIS-10.403
eor-1Protein EOR-10.399
hcp-3Protein HCP-30.397
egl-45Protein EGL-450.395
daf-3Protein DAF-30.394
bet-1Protein BET-10.390
CELE_F10G7.9Protein F10G7.90.384
eif-3.DProtein EIF-3.D0.384
skp-1Protein SKP-10.379
fars-1Protein FARS-10.377
peb-1Protein PEB-10.376
daf-14Protein DAF-140.374
C14C10.4Protein C14C10.40.372
mig-32Protein MIG-320.372
ztf-2Protein ZTF-20.370
nud-1Protein NUD-10.367
pie-1Protein PIE-10.365
pbrm-1Protein PBRM-10.364
rsp-1Protein RSP-10.363
his-42Protein HIS-420.361
daf-1Protein DAF-10.354
eif-3.BProtein EIF-3.B0.354
klp-15Protein KLP-150.353
rps-2Protein RPS-20.352
lin-11Protein LIN-110.349
nol-1Protein NOL-10.346
rpl-4Protein RPL-40.344
pas-5Protein PAS-50.344
R05F9.9Protein R05F9.90.342
T28D9.4Protein T28D9.40.336
let-502Protein LET-5020.336
mcm-7Protein MCM-70.331
D2085.3Protein D2085.30.329
egl-46Protein EGL-460.329
glp-1Protein GLP-10.324
unc-52Protein UNC-520.320
hlh-1Protein HLH-10.319
pry-1Protein PRY-10.318
klp-7Protein KLP-70.317
dsh-2Protein DSH-20.317
his-16Protein HIS-160.315
zyg-1Protein ZYG-10.313
his-61Protein HIS-610.312
hmg-1.2Protein HMG-1.20.311
mig-6Protein MIG-60.310
pabp-2Protein PABP-20.310
lin-35Protein LIN-350.309
F40F4.7Protein F40F4.70.309
cfim-2Protein CFIM-20.307
aap-1Protein AAP-10.302
mix-1Protein MIX-10.301
swsn-2.1Protein SWSN-2.10.299
mes-4Protein MES-40.295
his-45Protein HIS-450.288
dpy-30Protein DPY-300.288
T28F4.1Protein T28F4.10.287
hcp-6Protein HCP-60.286
lsm-1Protein LSM-10.281
his-3Protein HIS-30.280
sams-3Protein SAMS-30.280
CELE_F17C11.10Protein F17C11.100.278
egl-8Protein EGL-80.277
elt-6Protein ELT-60.276
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism