The network for 'cardiac ventricle morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac ventricle morphogenesis

The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.897
mef2cbmyocyte enhancer factor 2cb0.642
myod1myogenic differentiation 10.539
tal1T-cell acute lymphocytic leukemia 10.425
tbx5aT-box 5a0.346
hnf1baHNF1 homeobox Ba0.293
hey2hairy/enhancer-of-split related with YRPW motif 20.281
tnnt2atroponin T2a, cardiac0.265
tnni1btroponin I, skeletal, slow b0.242
gata5GATA-binding protein 50.232
tnnt3btroponin T3b, skeletal, fast0.207
ttnatitin a0.195
smyhc1slow myosin heavy chain 10.193
smyhc1lslow myosin heavy chain 1, like0.183
smyd1bSET and MYND domain containing 1b0.177
rbm24aRNA binding motif protein 24a0.175
gpr126G protein-coupled receptor 1260.118
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.110
actn3bactinin alpha 3b0.109
lmx1b.1LIM homeobox transcription factor 1, beta 10.102
notch3notch homolog 30.094
tnni1altroponin I, skeletal, slow like0.092
etv2ets variant gene 20.092
tnnt3atroponin T3a, skeletal, fast0.090
gata2aGATA-binding protein 2a0.085
znf148zinc finger protein 1480.078
tbx20T-box 200.076
wnt11rwingless-type MMTV integration site family, member 11, related0.070
hhexhematopoietically expressed homeobox0.067
aplnrbapelin receptor b0.066
vmhcventricular myosin heavy chain0.065
smyhc2slow myosin heavy chain 20.065
tnnc1btroponin C type 1b (slow)0.064
nkx2.5NK2 transcription factor related 50.064
tnnc2troponin C type 2 (fast)0.062
wlswntless homolog (Drosophila)0.059
actc1aactin, alpha, cardiac muscle 1a0.059
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.059
tmem88atransmembrane protein 88 a0.054
wif1wnt inhibitory factor 10.054
isl1islet10.053
ckmacreatine kinase, muscle a0.052
col5a1procollagen, type V, alpha 10.050
trpc1transient receptor potential cation channel, subfamily C, member 10.050
cdh2cadherin 2, neuronal0.048
tnni2a.4troponin I, skeletal, fast 2a.40.047
spon1bspondin 1b0.042
col11a1bcollagen type XI alpha-1b and collagen, type XI, alpha 1b0.042
cmlc1cardiac myosin light chain-10.041
pcdh10bprotocadherin 10b0.040
bmp2bbone morphogenetic protein 2b0.040
alcamaactivated leukocyte cell adhesion molecule a0.039
bmp4bone morphogenetic protein 40.038
foxi1forkhead box I10.037
edn1endothelin 10.037
arnt2aryl hydrocarbon receptor nuclear translocator 20.036
pld1aphospholipase D1a0.033
pdlim7PDZ and LIM domain 70.033
flt4fms-related tyrosine kinase 40.033
atp2a2aATPase, Ca++ transporting, cardiac muscle, slow twitch 2a0.032
foxc1aforkhead box C1a0.030
tmem2transmembrane protein 20.030
fn1fibronectin 10.030
mybpc3myosin binding protein C, cardiac0.029
wnt2bbwingless-type MMTV integration site family, member 2Bb0.029
ogg18-oxoguanine DNA glycosylase0.028
has2hyaluronan synthase 20.027
jag1bjagged 1b0.026
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.026
aldh1a2aldehyde dehydrogenase 1 family, member A20.025
kdrlkinase insert domain receptor like0.025
unc45bunc-45 homolog B (C. elegans)0.024
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.024
mibmind bomb0.023
dlx4bdistal-less homeobox gene 4b0.023
fgf18afibroblast growth factor 18a0.023
myl7myosin, light polypeptide 7, regulatory0.021
lmo2LIM domain only 2 (rhombotin-like 1)0.021
hand2heart and neural crest derivatives expressed transcript 20.020
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.020
oepone-eyed pinhead0.019
tpmaalpha-tropomyosin0.019
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.018
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.018
dzip1DAZ interacting protein 10.018
coro1bcoronin, actin binding protein, 1B0.017
cx36.7connexin 36.70.017
tln1talin 10.016
hmx2H6 family homeobox 20.016
eya4eyes absent homolog 4 (Drosophila)0.015
sulf2lsulfatase 2, like0.015
hspb7heat shock protein family, alpha-crystallin-related, b70.014
bmp3bone morphogenetic protein 30.014
nppanatriuretic peptide precursor A0.014
ccm2cerebral cavernous malformation 20.014
myl1myosin, light chain 1, alkali; skeletal, fast0.013
pax6bpaired box gene 6b0.013
igfbp3insulin-like growth factor binding protein 30.013
snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.013
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TNNC1troponin C type 1 (slow)1.000
TNNI1troponin I type 1 (skeletal, slow)0.998
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.983
TPM1tropomyosin 1 (alpha)0.964
NOTCH1notch 10.860
EP300E1A binding protein p3000.833
NOTCH3notch 30.827
SMYD1SET and MYND domain containing 10.818
TBX5T-box 50.796
TNNT2troponin T type 2 (cardiac)0.754
COX6A2cytochrome c oxidase subunit VIa polypeptide 20.708
NCOA1nuclear receptor coactivator 10.699
MED25mediator complex subunit 250.694
TNNI2troponin I type 2 (skeletal, fast)0.647
TPM2tropomyosin 2 (beta)0.607
CKMcreatine kinase, muscle0.581
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.549
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.530
HAP1huntingtin-associated protein 10.509
ACTA1actin, alpha 1, skeletal muscle0.507
MYL1myosin, light chain 1, alkali; skeletal, fast0.496
MYH7myosin, heavy chain 7, cardiac muscle, beta0.469
ATP2A1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.423
SMAD9SMAD family member 90.392
SFNstratifin0.384
MYH1myosin, heavy chain 1, skeletal muscle, adult0.355
DSPdesmoplakin0.350
ESR1estrogen receptor 10.324
MYL2myosin, light chain 2, regulatory, cardiac, slow0.322
LDB3LIM domain binding 30.321
TNNT1troponin T type 1 (skeletal, slow)0.310
ACVR1Bactivin A receptor, type IB0.305
TNNT3troponin T type 3 (skeletal, fast)0.302
FGF10fibroblast growth factor 100.292
MYOD1myogenic differentiation 10.284
TRIM63tripartite motif containing 630.265
GATA4GATA binding protein 40.257
MYH9myosin, heavy chain 9, non-muscle0.238
KRT14keratin 140.235
MYLPFmyosin light chain, phosphorylatable, fast skeletal muscle0.234
MYH2myosin, heavy chain 2, skeletal muscle, adult0.227
MYL4myosin, light chain 4, alkali; atrial, embryonic0.223
PDLIM7PDZ and LIM domain 7 (enigma)0.208
JUPjunction plakoglobin0.193
TNNC2troponin C type 2 (fast)0.188
DESdesmin0.187
GATA2GATA binding protein 20.178
FGF1fibroblast growth factor 1 (acidic)0.170
MYBPC2myosin binding protein C, fast type0.167
VCPvalosin containing protein0.161
HNF4Ahepatocyte nuclear factor 4, alpha0.160
JAG1jagged 10.150
ESR2estrogen receptor 2 (ER beta)0.148
GSK3Bglycogen synthase kinase 3 beta0.130
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.127
HEYLhairy/enhancer-of-split related with YRPW motif-like0.120
SMAD3SMAD family member 30.119
CXXC5CXXC finger protein 50.116
SGCAsarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)0.115
RARAretinoic acid receptor, alpha0.110
CTBP2C-terminal binding protein 20.108
ACTN3actinin, alpha 30.103
GATA1GATA binding protein 1 (globin transcription factor 1)0.098
RB1retinoblastoma 10.097
KAT2BK(lysine) acetyltransferase 2B0.096
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow0.092
KRT8keratin 80.091
MYH6myosin, heavy chain 6, cardiac muscle, alpha0.091
TAL1T-cell acute lymphocytic leukemia 10.089
MYBPC1myosin binding protein C, slow type0.087
ACTC1actin, alpha, cardiac muscle 10.082
TGFBR1transforming growth factor, beta receptor 10.080
PSEN1presenilin 10.079
PKP2plakophilin 20.074
ARNTaryl hydrocarbon receptor nuclear translocator0.071
TNS4tensin 40.070
MYL12Bmyosin, light chain 12B, regulatory0.068
EPAS1endothelial PAS domain protein 10.068
PTPRJprotein tyrosine phosphatase, receptor type, J0.064
PAX8paired box 80.062
AKAP12A kinase (PRKA) anchor protein 120.061
MAML1mastermind-like 1 (Drosophila)0.060
HIPK2homeodomain interacting protein kinase 20.060
RIPK3receptor-interacting serine-threonine kinase 30.059
SOX11SRY (sex determining region Y)-box 110.058
CORO1Ccoronin, actin binding protein, 1C0.056
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.053
ACTN2actinin, alpha 20.052
SOX7SRY (sex determining region Y)-box 70.048
CCKcholecystokinin0.046
PDE4DIPphosphodiesterase 4D interacting protein0.046
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.046
SMAD2SMAD family member 20.044
FLNAfilamin A, alpha0.043
MYL12Amyosin, light chain 12A, regulatory, non-sarcomeric0.043
NSFL1CNSFL1 (p97) cofactor (p47)0.041
NOTCH2notch 20.040
PMLpromyelocytic leukemia0.039
DSG2desmoglein 20.038
MTORmechanistic target of rapamycin (serine/threonine kinase)0.038
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax2paired box gene 21.000
Hand2heart and neural crest derivatives expressed transcript 21.000
Fgfr2fibroblast growth factor receptor 21.000
Pitx2paired-like homeodomain transcription factor 21.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.999
Notch1Notch gene homolog 1 (Drosophila)0.996
Isl1ISL1 transcription factor, LIM/homeodomain0.995
Gli3GLI-Kruppel family member GLI30.993
Fgf8fibroblast growth factor 80.993
Gata4GATA binding protein 40.988
Foxc2forkhead box C20.986
Foxg1forkhead box G10.984
Pax3paired box gene 30.984
Sox2SRY-box containing gene 20.983
Sall4sal-like 4 (Drosophila)0.978
Hoxd13homeobox D130.969
Ctnnb1catenin (cadherin associated protein), beta 10.966
Chd7chromodomain helicase DNA binding protein 70.966
Pax6paired box gene 60.964
Hand1heart and neural crest derivatives expressed transcript 10.963
Tbx1T-box 10.959
Bmp4bone morphogenetic protein 40.957
Foxh1forkhead box H10.949
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.943
Lhx1LIM homeobox protein 10.931
Meox2mesenchyme homeobox 20.930
Nognoggin0.927
Foxc1forkhead box C10.919
Tlx3T-cell leukemia, homeobox 30.911
Hoxa13homeobox A130.906
Gbx2gastrulation brain homeobox 20.906
Emx1empty spiracles homolog 1 (Drosophila)0.904
Tbx3T-box 30.868
Tcfcp2l1transcription factor CP2-like 10.861
Ascl1achaete-scute complex homolog 1 (Drosophila)0.860
Jag1jagged 10.859
Eya1eyes absent 1 homolog (Drosophila)0.859
Emx2empty spiracles homolog 2 (Drosophila)0.858
Lmx1bLIM homeobox transcription factor 1 beta0.853
Hoxa1homeobox A10.849
Hoxd11homeobox D110.840
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.833
Sox11SRY-box containing gene 110.813
Efnb2ephrin B20.809
Insm1insulinoma-associated 10.808
Zeb1zinc finger E-box binding homeobox 10.807
Pax8paired box gene 80.806
Smad4MAD homolog 4 (Drosophila)0.798
Foxa2forkhead box A20.787
Nodalnodal0.786
Col1a1collagen, type I, alpha 10.782
Gata6GATA binding protein 60.782
Dll4delta-like 4 (Drosophila)0.771
Vangl2vang-like 2 (van gogh, Drosophila)0.770
Esrrbestrogen related receptor, beta0.764
Gli2GLI-Kruppel family member GLI20.755
Pthlhparathyroid hormone-like peptide0.744
Pou4f2POU domain, class 4, transcription factor 20.733
Rargretinoic acid receptor, gamma0.723
Smad6MAD homolog 6 (Drosophila)0.723
Fgf3fibroblast growth factor 30.721
Shesrc homology 2 domain-containing transforming protein E0.712
Hes1hairy and enhancer of split 1 (Drosophila)0.703
Fgfr1fibroblast growth factor receptor 10.690
Hmx3H6 homeobox 30.686
Tcfap2atranscription factor AP-2, alpha0.678
Pax1paired box gene 10.675
Lmx1aLIM homeobox transcription factor 1 alpha0.670
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.669
Tgfb2transforming growth factor, beta 20.665
Sox18SRY-box containing gene 180.664
Rxraretinoid X receptor alpha0.658
Nos3nitric oxide synthase 3, endothelial cell0.653
En1engrailed 10.649
Pitx1paired-like homeodomain transcription factor 10.626
Atoh1atonal homolog 1 (Drosophila)0.600
Ptf1apancreas specific transcription factor, 1a0.573
Ptpn11protein tyrosine phosphatase, non-receptor type 110.550
Dlx2distal-less homeobox 20.542
Hes5hairy and enhancer of split 5 (Drosophila)0.540
UncxUNC homeobox0.528
Hey2hairy/enhancer-of-split related with YRPW motif 20.516
Hoxd3homeobox D30.516
Pou3f3POU domain, class 3, transcription factor 30.512
Nkx2-1NK2 homeobox 10.504
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.502
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.501
Otx1orthodenticle homolog 1 (Drosophila)0.486
Lhx3LIM homeobox protein 30.478
Zic3zinc finger protein of the cerebellum 30.476
Sox3SRY-box containing gene 30.468
Hoxa10homeobox A100.463
Neurod4neurogenic differentiation 40.458
Myl3myosin, light polypeptide 30.450
Fgfr3fibroblast growth factor receptor 30.450
Gdf5growth differentiation factor 50.442
Neurog2neurogenin 20.441
Axin1axin 10.439
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism