The network for 'response to stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

NameDescriptionProbabilityFunc Analog Organism
pea3ETS-domain transcription factor pea30.979
bmp2bbone morphogenetic protein 2b0.913
cdh1cadherin 1, epithelial0.911
pitx3paired-like homeodomain transcription factor 30.911
osr1odd-skipped related 1 (Drosophila)0.897
shhasonic hedgehog a0.896
lamc1laminin, gamma 10.889
tal1T-cell acute lymphocytic leukemia 10.885
igf1rainsulin-like growth factor 1a receptor0.880
apoebapolipoprotein Eb0.880
fgf3fibroblast growth factor 30.874
gro1groucho 10.871
nkx3.2NK3 homeobox 20.856
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.851
hspa5heat shock protein 50.845
gata5GATA-binding protein 50.822
gscgoosecoid0.803
thtyrosine hydroxylase0.761
gli1GLI-Kruppel family member 10.760
igfbp1ainsulin-like growth factor binding protein 1a0.752
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.739
hmgb2bhigh-mobility group box 2b0.729
cx43connexin 430.728
fgfr1afibroblast growth factor receptor 1a0.725
otpaorthopedia homolog a0.724
col8a1acollagen, type VIII, alpha 1a0.701
vaspvasodilator-stimulated phosphoprotein0.700
tagln2transgelin 20.697
gpiaglucose phosphate isomerase a0.696
evx1even-skipped homeobox 10.681
twist3twist30.680
brd2abromodomain-containing 2a0.671
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.670
notch3notch homolog 30.669
mycbp2MYC binding protein 20.666
wlswntless homolog (Drosophila)0.666
sox32SRY-box containing gene 320.665
ef1aelongation factor 1-alpha0.657
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.640
pax7apaired box gene 7a0.639
vasavasa homolog0.639
ddb2damage-specific DNA binding protein 20.637
rhoabras homolog gene family, member Ab0.636
kitakit receptor a0.634
cav1caveolin 10.631
robo3roundabout homolog 30.623
ca8carbonic anhydrase VIII0.614
hsp90b1heat shock protein 90, beta (grp94), member 10.605
smad1MAD homolog 1 (Drosophila)0.598
ctsl1acathepsin L, 1 a0.594
mstnbmyostatin b0.594
hmga1ahigh mobility group AT-hook 1a0.586
sox19aSRY-box containing gene 19a0.578
dbx1adeveloping brain homeobox 1a0.577
alcambactivated leukocyte cell adhesion molecule b0.565
junbjun B proto-oncogene0.561
tlr21toll-like receptor 210.561
wnt2wingless-type MMTV integration site family member 20.555
spry4sprouty (Drosophila) homolog 40.552
sh3gl1bSH3-domain GRB2-like 1b0.551
fabp7afatty acid binding protein 7, brain, a0.537
runx1runt-related transcription factor 10.535
sat1aspermidine/spermine N1-acetyltransferase 1a0.533
appaamyloid beta (A4) precursor protein a0.531
epas1bendothelial PAS domain protein 1b0.525
wnt11rwingless-type MMTV integration site family, member 11, related0.523
ccnd1cyclin D10.513
mmp9matrix metalloproteinase 90.511
socs1suppressor of cytokine signaling 10.511
bmp4bone morphogenetic protein 40.509
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.509
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.503
tbx18T-box 180.499
igf1insulin-like growth factor 10.493
pycardPYD and CARD domain containing0.487
naspnuclear autoantigenic sperm protein (histone-binding)0.483
dusp6dual specificity phosphatase 60.483
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.478
scribscribbled homolog (Drosophila)0.477
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.475
nod1nucleotide-binding oligomerization domain containing 10.474
cx39.9connexin 39.90.471
cry3cryptochrome 30.471
adra2dbadrenergic, alpha-2D-, receptor b0.471
id1inhibitor of DNA binding 10.470
vcpvalosin containing protein0.467
fzd5frizzled homolog 50.465
fzd7afrizzled homolog 7a0.460
lhx8aLIM homeobox 8a0.459
junbljun B proto-oncogene, like0.458
il1binterleukin 1, beta and interleukin 1, beta0.458
lmx1b.1LIM homeobox transcription factor 1, beta 10.456
atoh1batonal homolog 1b0.455
neurog3neurogenin 30.454
msh6mutS homolog 6 (E. coli)0.453
igf1rbinsulin-like growth factor 1b receptor0.452
bmperBMP binding endothelial regulator0.451
spry2sprouty homolog 20.451
foxd3forkhead box D30.451
rasl11bRAS-like, family 11, member B0.450
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism