The network for 'renal filtration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

renal filtration

A renal system process in which fluid circulating through the body is filtered through a barrier system.

NameDescriptionProbabilityFunc Analog Organism
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.331
wt1bwilms tumor 1b0.299
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.258
vegfabvascular endothelial growth factor Ab0.255
lrp2low density lipoprotein-related protein 20.249
crb3bcrumbs homolog 3b0.196
wtipWilms tumor 1 interacting protein0.170
epb41l5erythrocyte membrane protein band 4.1 like 50.160
smchd1structural maintenance of chromosomes flexible hinge domain containing 10.132
col5a1procollagen, type V, alpha 10.105
emp2epithelial membrane protein 20.105
kdrlkinase insert domain receptor like0.087
f2rcoagulation factor II (thrombin) receptor0.084
crb2acrumbs homolog 2a0.077
jam2bjunctional adhesion molecule 2b0.076
vegfaavascular endothelial growth factor Aa0.061
crb3acrumbs homolog 3a0.051
ahr2aryl hydrocarbon receptor 20.049
sulf2lsulfatase 2, like0.047
crb2bcrumbs homolog 2b0.039
plcd1bphospholipase C, delta 1b0.038
colec11collectin sub-family member 110.036
sdprbserum deprivation response b0.034
nr2f1anuclear receptor subfamily 2, group F, member 1a0.033
cacna1dacalcium channel, voltage-dependent, L type, alpha 1D subunit, a0.032
hgfahepatocyte growth factor a0.032
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.030
kirrelbkin of IRRE like b0.028
ehd2EH-domain containing 20.027
grk7aG-protein-coupled receptor kinase 7a0.026
dnmt8DNA (cytosine-5-)-methyltransferase 80.026
lmo2LIM domain only 2 (rhombotin-like 1)0.026
sema3fbsemaphorin 3fb0.025
cd248aCD248 molecule, endosialin a0.025
sfrp2secreted frizzled-related protein 20.024
tsc2tuberous sclerosis 20.024
hapln1ahyaluronan and proteoglycan link protein 1a0.021
s1pr1sphingosine-1-phosphate receptor 10.021
mpp5bmembrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b)0.020
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.020
msnamoesin a0.019
rp2retinitis pigmentosa 2 (X-linked recessive)0.019
slc4a4asolute carrier family 4, member 4a0.018
sulf2sulfatase 20.018
LOC567965rho GTPase-activating protein 7-like0.018
s1pr2sphingosine-1-phosphate receptor 20.017
hoxc11ahomeo box C11a0.017
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.017
clrn1clarin 10.017
kirrel3lkin of IRRE like 3 like0.016
ahnakAHNAK nucleoprotein0.016
foxo3bforkhead box O3b0.016
dctn1adynactin 1a0.016
plxnd1plexin D10.015
mrc1amannose receptor, C type 1a0.015
cldniclaudin i0.015
ccbe1collagen and calcium binding EGF domains 10.015
stat1asignal transduction and activation of transcription 1a0.014
tjp2atight junction protein 2a (zona occludens 2)0.014
foxj1bforkhead box J1b0.014
ier2immediate early response 20.013
cahzcarbonic anhydrase0.013
crb1crumbs homolog 1 (Drosophila)0.013
tpp1tripeptidyl peptidase I0.013
hnf1bbHNF1 homeobox Bb0.013
cdh17cadherin 17, LI cadherin (liver-intestine)0.013
slc4a1asolute carrier family 4, anion exchanger, member 1a0.013
b3gnt7UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 70.013
fgfrl1afibroblast growth factor receptor-like 1a0.013
emilin1aelastin microfibril interfacer 1a0.013
col6a3collagen, type VI, alpha 30.013
jag1bjagged 1b0.012
ppoxprotoporphyrinogen oxidase0.012
timp2btissue inhibitor of metalloproteinase 2b0.012
krcpkelch repeat-containing protein0.012
fli1afriend leukemia integration 1a0.012
skibnuclear oncoprotein skib0.012
igf2binsulin-like growth factor 2b0.012
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.011
tmem88atransmembrane protein 88 a0.011
iclp1invariant chain-like protein 10.011
cdh5cadherin 50.011
tnfsf10l2tumor necrosis factor (ligand) superfamily, member 10 like 20.010
f11rF11 receptor0.010
cplx4acomplexin 4a0.010
osr2odd-skipped related 2 (Drosophila)0.010
fam43bfamily with sequence similarity 43, member B0.010
grk1bG protein-coupled receptor kinase 1 b0.010
vat1vesicle amine transport protein 1 homolog (T californica)0.010
slc20a1asolute carrier family 20, member 1a0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Cdc42CG12530 gene product from transcript CG12530-RA0.966
snssticks and stones0.848
kirrekin of irre0.696
AblAbl tyrosine kinase0.283
Rho1CG8416 gene product from transcript CG8416-RB0.160
CG11592CG11592 gene product from transcript CG11592-RA0.142
Mec2CG7635 gene product from transcript CG7635-RA0.118
rolsrolling pebbles0.114
CHES-1-likeCheckpoint suppressor homologue0.112
X11LCG5675 gene product from transcript CG5675-RB0.096
HandCG18144 gene product from transcript CG18144-RA0.075
LanB1CG7123 gene product from transcript CG7123-RA0.059
PvrPDGF- and VEGF-receptor related0.050
hipkhomeodomain interacting protein kinase0.049
MrtfMyocardin-related transcription factor0.036
S6kIIRPS6-protein kinase-II0.032
pod1CG4532 gene product from transcript CG4532-RF0.030
CG32702CG32702 gene product from transcript CG32702-RB0.029
zfh1Zn finger homeodomain 10.029
CG12321CG12321 gene product from transcript CG12321-RA0.017
Trxr-2thioredoxin reductase 20.017
fasfaint sausage0.016
lmdlame duck0.016
CG8728CG8728 gene product from transcript CG8728-RA0.014
CG15803CG15803 gene product from transcript CG15803-RB0.014
ClicChloride intracellular channel0.011
wbwing blister0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.302
FHL2four and a half LIM domains 20.014
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cd151CD151 antigen0.668
Nos3nitric oxide synthase 3, endothelial cell0.386
Nrp1neuropilin 10.220
Foxc2forkhead box C20.167
Acvrl1activin A receptor, type II-like 10.154
Kdrkinase insert domain protein receptor0.149
Trpv1transient receptor potential cation channel, subfamily V, member 10.084
Nphs2nephrosis 2 homolog, podocin (human)0.083
Tinagl1tubulointerstitial nephritis antigen-like 10.066
Hbegfheparin-binding EGF-like growth factor0.063
Flt1FMS-like tyrosine kinase 10.059
Flt4FMS-like tyrosine kinase 40.057
Pdgfbplatelet derived growth factor, B polypeptide0.049
Lmnalamin A0.043
Tenc1tensin like C1 domain-containing phosphatase0.042
Pcdh15protocadherin 150.041
Epas1endothelial PAS domain protein 10.040
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.035
Ush1cUsher syndrome 1C homolog (human)0.035
Cdh5cadherin 50.031
Wwc2WW, C2 and coiled-coil domain containing 20.027
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.026
Tgfb2transforming growth factor, beta 20.026
Ltbp1latent transforming growth factor beta binding protein 10.025
Tspan9tetraspanin 90.025
Notch2Notch gene homolog 2 (Drosophila)0.024
Acvr1activin A receptor, type 10.022
Ren1renin 1 structural0.022
Jupjunction plakoglobin0.021
Ilkintegrin linked kinase0.021
Itga5integrin alpha 5 (fibronectin receptor alpha)0.019
Sulf2sulfatase 20.018
Phlda3pleckstrin homology-like domain, family A, member 30.017
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.016
Tgfbr2transforming growth factor, beta receptor II0.016
Ptgs1prostaglandin-endoperoxide synthase 10.015
Nid1nidogen 10.014
Pvrpoliovirus receptor0.013
Wwtr1WW domain containing transcription regulator 10.013
Rhojras homolog gene family, member J0.012
Lama5laminin, alpha 50.012
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.012
Pdgfcplatelet-derived growth factor, C polypeptide0.012
Col4a4collagen, type IV, alpha 40.012
Rem1rad and gem related GTP binding protein 10.012
Prrx1paired related homeobox 10.012
Slc12a4solute carrier family 12, member 40.011
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.011
Npr3natriuretic peptide receptor 30.011
Wt1Wilms tumor 1 homolog0.011
Plaurplasminogen activator, urokinase receptor0.011
Phldb2pleckstrin homology-like domain, family B, member 20.011
Lrrk2leucine-rich repeat kinase 20.010
Fzd4frizzled homolog 4 (Drosophila)0.010
Bmp6bone morphogenetic protein 60.010
Sulf1sulfatase 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nrg1neuregulin 10.278
Gja5gap junction protein, alpha 50.262
Ptafrplatelet-activating factor receptor0.227
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.133
Esamendothelial cell adhesion molecule0.130
Tff1trefoil factor 10.100
Calcbcalcitonin-related polypeptide, beta0.076
Ednraendothelin receptor type A0.072
Fgf2fibroblast growth factor 20.072
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.065
Magmyelin-associated glycoprotein0.064
S1pr2sphingosine-1-phosphate receptor 20.064
Ptgfrprostaglandin F receptor0.048
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.046
Nraddneurotrophin receptor associated death domain0.046
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.045
Marcksmyristoylated alanine rich protein kinase C substrate0.043
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.043
Prss22protease, serine, 220.042
Gfapglial fibrillary acidic protein0.041
Prkchprotein kinase C, eta0.037
Cst12cystatin 120.035
Tmem88transmembrane protein 880.035
Actn1actinin, alpha 10.034
Arnt2aryl hydrocarbon receptor nuclear translocator 20.032
Olr287olfactory receptor 2870.031
Gja6gap junction protein, alpha 60.029
Gnb4guanine nucleotide binding protein (G protein), beta polypeptide 40.028
Olr857olfactory receptor 8570.028
Tcf4transcription factor 40.027
Tpbpatrophoblast specific protein alpha0.027
Eaf1ELL associated factor 10.026
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.025
Olr226olfactory receptor 2260.025
Pspparotid secretory protein0.024
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.024
Acvrl1activin A receptor type II-like 10.024
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.023
Vom2r27vomeronasal 2 receptor, 270.023
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.023
Slc14a2solute carrier family 14 (urea transporter), member 20.021
F2rl1coagulation factor II (thrombin) receptor-like 10.020
Atxn1ataxin 10.019
Lhcgrluteinizing hormone/choriogonadotropin receptor0.019
Ppap2bphosphatidic acid phosphatase type 2B0.018
Pde5aphosphodiesterase 5A, cGMP-specific0.017
Calcrlcalcitonin receptor-like0.017
Trhthyrotropin releasing hormone0.017
RhcgRh family, C glycoprotein0.016
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.016
Cckarcholecystokinin A receptor0.016
Rararetinoic acid receptor, alpha0.016
Ctnnd1catenin (cadherin associated protein), delta 10.015
Il6interleukin 60.015
Plxnb2plexin B20.015
RGD1565772similar to hypothetical protein A430110N230.015
Dll3delta-like 3 (Drosophila)0.015
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.015
Il1rninterleukin 1 receptor antagonist0.015
Myh11myosin, heavy chain 11, smooth muscle0.014
Scnn1asodium channel, nonvoltage-gated 1 alpha0.014
Timp3TIMP metallopeptidase inhibitor 30.014
Sfrp4secreted frizzled-related protein 40.014
LOC60591calcium-activated potassium channel beta subunit0.013
Rnase1ribonuclease, RNase A family, 1 (pancreatic)0.013
Ehd2EH-domain containing 20.013
Nos3nitric oxide synthase 3, endothelial cell0.013
Alox5arachidonate 5-lipoxygenase0.013
Prpg1proline-rich proteoglycan 10.013
Igfbp2insulin-like growth factor binding protein 20.013
Gata6GATA binding protein 60.013
Ednrbendothelin receptor type B0.012
Strnstriatin, calmodulin binding protein0.012
Ehd4EH-domain containing 40.012
Vom2r53vomeronasal 2 receptor, 530.012
Marcksl1MARCKS-like 10.012
Aqp4aquaporin 40.012
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.012
Avpr2arginine vasopressin receptor 20.012
Wwtr1WW domain containing transcription regulator 10.011
Cpb1carboxypeptidase B1 (tissue)0.011
Igfbp5insulin-like growth factor binding protein 50.011
Chrm2cholinergic receptor, muscarinic 20.011
Map4k4mitogen-activated protein kinase kinase kinase kinase 40.011
Padi1peptidyl arginine deiminase, type I0.011
Tnftumor necrosis factor (TNF superfamily, member 2)0.011
Dusp7dual specificity phosphatase 70.011
Adra2aadrenergic, alpha-2A-, receptor0.011
Cxcl2chemokine (C-X-C motif) ligand 20.011
Foxi2forkhead box I20.011
Itgamintegrin, alpha M0.010
Fbln1fibulin 10.010
Dusp6dual specificity phosphatase 60.010
Dock8dedicator of cytokinesis 80.010
Ptprz1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism