The network for 'positive regulation of camp metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of camp metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

NameDescriptionProbabilityFunc Analog Organism
LOC100003330melanocortin-2 receptor accessory protein 2-like0.804
mc2rmelanocortin 2 receptor0.796
adrb2aadrenergic receptor, beta 2a0.679
mc4rmelanocortin 4 receptor0.633
mc1rmelanocortin 1 receptor0.631
uts1urotensin 10.619
mc5ramelanocortin 5a receptor0.619
mc3rmelanocortin 3 receptor0.575
mc5rbmelanocortin 5b receptor0.527
nf1aneurofibromin 1a0.425
nf1bneurofibromin 1b0.375
LOC569642hypothetical protein LOC5696420.314
LOC555482tachykinin receptor 3-like0.302
LOC559201similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)0.268
fgf6afibroblast growth factor 6a0.228
igf3insulin-like growth factor 30.220
gap43growth associated protein 430.206
rps2ribosomal protein S20.175
fesfeline sarcoma oncogene0.168
adipoqladiponectin, C1Q and collagen domain containing, like0.156
chrnb3bcholinergic receptor, nicotinic, beta polypeptide 3b0.150
cyp11b2cytochrome P450, family 11, subfamily B, polypeptide 20.143
rtn1areticulon 1a0.130
vipr2vasoactive intestinal peptide receptor 20.126
arpc5aactin related protein 2/3 complex, subunit 5A0.122
adrb1adrenergic receptor, beta 10.122
drd2ldopamine receptor D2 like0.122
gnrh3gonadotropin-releasing hormone 30.115
rag1recombination activating gene 10.114
paqr8progestin and adipoQ receptor family member VIII0.114
drd2bdopamine receptor D2b0.113
ryr2aryanodine receptor 2a (cardiac)0.105
trpc1transient receptor potential cation channel, subfamily C, member 10.101
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.099
th2tyrosine hydroxylase 20.099
calcrlacalcitonin receptor-like a0.097
ros1v-ros UR2 sarcoma virus oncogene homolog 1 (avian)0.097
inhainhibin, alpha0.096
chrm2acholinergic receptor, muscarinic 2a0.088
efemp2EGF-containing fibulin-like extracellular matrix protein 20.087
ryr3ryanodine receptor 30.086
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.084
vegfabvascular endothelial growth factor Ab0.082
LOC100536464protein FAM126B-like0.078
c1qtnf4C1q and tumor necrosis factor related protein 40.077
ttc39ctetratricopeptide repeat domain 39C0.072
dbhdopamine beta hydroxylase0.071
LOC563363cholesterol side-chain cleavage enzyme, mitochondrial-like0.069
avplarginine vasopressin-like0.068
or115-10odorant receptor, family F, subfamily 115, member 100.067
gnrh2gonadotropin-releasing hormone 20.066
LOC565839tumor necrosis factor alpha-induced protein 2-like0.066
penkaproenkephalin a0.064
tspan7btetraspanin 7b0.063
terttelomerase reverse transcriptase0.063
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.059
gria2bglutamate receptor, ionotropic, AMPA 2b0.058
rhogcras homolog gene family, member Gc0.058
drd3dopamine receptor D30.056
LOC100150924DNA polymerase subunit gamma-1-like0.056
gfra1bgdnf family receptor alpha 1b0.055
fshrfollicle stimulating hormone receptor0.055
mapk8bmitogen-activated protein kinase 8b0.055
ppargperoxisome proliferator activated receptor gamma0.053
chrna4cholinergic receptor, nicotinic, alpha 40.052
paqr7bprogestin and adipoQ receptor family member VII, b0.049
ppiapeptidylprolyl isomerase A (cyclophilin A)0.049
cfdlcomplement factor D (adipsin) like0.047
gsdfgonadal somatic cell derived factor0.046
slco1f1solute carrier organic anion transporter family, member 1F10.046
calb2bcalbindin 2b, (calretinin)0.046
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.046
smtnbsmoothelin b0.045
bhlha15basic helix-loop-helix family, member a150.044
adrb2badrenergic receptor, beta 2b0.044
spon1aspondin 1a0.043
vtg1vitellogenin 10.043
igfbp6ainsulin-like growth factor binding protein 6a0.043
alkanaplastic lymphoma kinase (Ki-1)0.043
or115-15odorant receptor, family F, subfamily 115, member 150.042
rap1bRAS related protein 1b0.039
ptrfbpolymerase I and transcript release factor b0.038
rhagRhesus blood group-associated glycoprotein0.038
esr1estrogen receptor 10.038
hdchistidine decarboxylase0.037
rln3arelaxin 3a0.037
cnga5cyclic nucleotide gated channel alpha 50.037
pyyapeptide YYa0.037
trpc5transient receptor potential cation channel, subfamily C, member 50.036
ilkintegrin linked kinase0.036
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Atf-2Activating transcription factor-20.099
CG13253CG13253 gene product from transcript CG13253-RB0.083
TbhTyramine beta hydroxylase0.076
dnr1defense repressor 10.075
CG42629CG42629 gene product from transcript CG42629-RB0.062
Pdp1PAR-domain protein 10.048
jebjelly belly0.047
oa2octopamine receptor 20.041
RanBPMRan-binding protein M0.032
tauCG31057 gene product from transcript CG31057-RA0.027
MadMothers against dpp0.025
CG34400CG34400 gene product from transcript CG34400-RD0.024
Rab11Rab-protein 110.021
Cdc42CG12530 gene product from transcript CG12530-RA0.019
Ef1alpha48DElongation factor 1alpha48D0.019
Nmdar1NMDA receptor 10.019
PIP5K59BCG3682 gene product from transcript CG3682-RE0.016
DhDiuretic hormone0.016
fd85Eforkhead domain 85E0.015
RicRas which interacts with Calmodulin0.014
Octbeta2RCG33976 gene product from transcript CG33976-RA0.013
CG11317CG11317 gene product from transcript CG11317-RA0.012
Eip63F-1Ecdysone-induced protein 63F 10.012
Ac3CG1506 gene product from transcript CG1506-RA0.012
CrebB-17ACyclic-AMP response element binding protein B at 17A0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.999
IL8interleukin 80.997
CALM1calmodulin 1 (phosphorylase kinase, delta)0.993
CCL5chemokine (C-C motif) ligand 50.989
ARRB1arrestin, beta 10.928
FHL1four and a half LIM domains 10.919
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.910
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.908
TBXA2Rthromboxane A2 receptor0.883
CCL20chemokine (C-C motif) ligand 200.876
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.873
CXCL2chemokine (C-X-C motif) ligand 20.851
CRHR1corticotropin releasing hormone receptor 10.844
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.816
CXCL3chemokine (C-X-C motif) ligand 30.815
DRD2dopamine receptor D20.809
CXCL10chemokine (C-X-C motif) ligand 100.806
IFNGinterferon, gamma0.799
CXCL11chemokine (C-X-C motif) ligand 110.792
CXCL9chemokine (C-X-C motif) ligand 90.780
IL1Binterleukin 1, beta0.757
MPDZmultiple PDZ domain protein0.748
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.687
IL6interleukin 6 (interferon, beta 2)0.638
CXCL5chemokine (C-X-C motif) ligand 50.630
CRHcorticotropin releasing hormone0.614
CCR2chemokine (C-C motif) receptor 20.604
PTGIRprostaglandin I2 (prostacyclin) receptor (IP)0.570
CCL22chemokine (C-C motif) ligand 220.526
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.482
DPP4dipeptidyl-peptidase 40.416
CXCR3chemokine (C-X-C motif) receptor 30.404
CALCRLcalcitonin receptor-like0.398
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.342
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.326
IL2RBinterleukin 2 receptor, beta0.312
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.310
NME4non-metastatic cells 4, protein expressed in0.297
CCL4chemokine (C-C motif) ligand 40.289
NAMPTnicotinamide phosphoribosyltransferase0.272
RGS1regulator of G-protein signaling 10.269
CCL8chemokine (C-C motif) ligand 80.258
CCR5chemokine (C-C motif) receptor 50.237
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.233
ADORA2Aadenosine A2a receptor0.230
NCF2neutrophil cytosolic factor 20.227
CCL11chemokine (C-C motif) ligand 110.208
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.205
CCR4chemokine (C-C motif) receptor 40.186
IL10interleukin 100.183
NME3non-metastatic cells 3, protein expressed in0.180
NUCB1nucleobindin 10.177
CCL7chemokine (C-C motif) ligand 70.176
CXCR5chemokine (C-X-C motif) receptor 50.175
LTAlymphotoxin alpha (TNF superfamily, member 1)0.167
SOD2superoxide dismutase 2, mitochondrial0.163
CXCR2chemokine (C-X-C motif) receptor 20.162
CD163CD163 molecule0.150
PF4platelet factor 40.149
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.147
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.144
GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 30.143
CCL2chemokine (C-C motif) ligand 20.135
CCL3chemokine (C-C motif) ligand 30.133
NME2non-metastatic cells 2, protein (NM23B) expressed in0.123
RALBP1ralA binding protein 10.121
CALCAcalcitonin-related polypeptide alpha0.115
FKBP8FK506 binding protein 8, 38kDa0.113
BZW1basic leucine zipper and W2 domains 10.111
CXCL13chemokine (C-X-C motif) ligand 130.110
CD40LGCD40 ligand0.100
CLEC7AC-type lectin domain family 7, member A0.098
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.095
GMFBglia maturation factor, beta0.092
PRDX4peroxiredoxin 40.092
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.088
SLAMF7SLAM family member 70.084
NME1non-metastatic cells 1, protein (NM23A) expressed in0.082
IRF4interferon regulatory factor 40.082
RALGDSral guanine nucleotide dissociation stimulator0.082
GHRHRgrowth hormone releasing hormone receptor0.080
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.079
BCL2A1BCL2-related protein A10.076
CYTIPcytohesin 1 interacting protein0.075
HTR45-hydroxytryptamine (serotonin) receptor 40.075
CCR9chemokine (C-C motif) receptor 90.074
MMP12matrix metallopeptidase 12 (macrophage elastase)0.074
PPBPpro-platelet basic protein (chemokine (C-X-C motif) ligand 7)0.073
SSTR3somatostatin receptor 30.071
CCR7chemokine (C-C motif) receptor 70.070
IL10RAinterleukin 10 receptor, alpha0.068
CCR8chemokine (C-C motif) receptor 80.067
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.066
CCL19chemokine (C-C motif) ligand 190.066
NRASneuroblastoma RAS viral (v-ras) oncogene homolog0.065
PAWRPRKC, apoptosis, WT1, regulator0.065
MEOX2mesenchyme homeobox 20.065
MC2Rmelanocortin 2 receptor (adrenocorticotropic hormone)0.064
CH25Hcholesterol 25-hydroxylase0.064
SELEselectin E0.062
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Drd2dopamine receptor D20.991
Crhr1corticotropin releasing hormone receptor 10.960
Arandrogen receptor0.948
Esr1estrogen receptor 1 (alpha)0.895
Ptenphosphatase and tensin homolog0.874
Cdkn1bcyclin-dependent kinase inhibitor 1B0.848
Pnpla2patatin-like phospholipase domain containing 20.841
Pgrprogesterone receptor0.811
Lhcgrluteinizing hormone/choriogonadotropin receptor0.707
Leprleptin receptor0.673
Ctnnb1catenin (cadherin associated protein), beta 10.601
Ghrgrowth hormone receptor0.523
Mc5rmelanocortin 5 receptor0.489
Nr3c1nuclear receptor subfamily 3, group C, member 10.489
Duox2dual oxidase 20.470
Sstr4somatostatin receptor 40.466
Ppargperoxisome proliferator activated receptor gamma0.463
Amhanti-Mullerian hormone0.450
Kiss1KiSS-1 metastasis-suppressor0.431
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.362
Thrbthyroid hormone receptor beta0.349
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.318
Fgf10fibroblast growth factor 100.312
Cgaglycoprotein hormones, alpha subunit0.281
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.262
Kiss1rKISS1 receptor0.260
Tac2tachykinin 20.248
Pax8paired box gene 80.244
BrafBraf transforming gene0.241
Cckbrcholecystokinin B receptor0.213
Tgfb1transforming growth factor, beta 10.203
Bglapbone gamma carboxyglutamate protein0.199
Ccnd1cyclin D10.189
Npy2rneuropeptide Y receptor Y20.189
Adra1aadrenergic receptor, alpha 1a0.187
Prlrprolactin receptor0.187
Adrb2adrenergic receptor, beta 20.178
Npc1Niemann Pick type C10.173
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.168
Cd247CD247 antigen0.162
Grid1glutamate receptor, ionotropic, delta 10.153
Htr75-hydroxytryptamine (serotonin) receptor 70.152
F2rl2coagulation factor II (thrombin) receptor-like 20.148
Pthlhparathyroid hormone-like peptide0.147
Nrasneuroblastoma ras oncogene0.142
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.141
Ednraendothelin receptor type A0.141
WwoxWW domain-containing oxidoreductase0.140
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.137
Esr2estrogen receptor 2 (beta)0.135
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.133
Apoeapolipoprotein E0.132
Apcadenomatosis polyposis coli0.130
Il5interleukin 50.125
Adora2aadenosine A2a receptor0.125
Tshrthyroid stimulating hormone receptor0.121
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.114
Adra2aadrenergic receptor, alpha 2a0.113
Krt86keratin 860.112
Gnrhrgonadotropin releasing hormone receptor0.109
Hif1ahypoxia inducible factor 1, alpha subunit0.108
Sntb1syntrophin, basic 10.107
Htr45 hydroxytryptamine (serotonin) receptor 40.105
Atp4aATPase, H+/K+ exchanging, gastric, alpha polypeptide0.101
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.100
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.100
Ptafrplatelet-activating factor receptor0.093
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.092
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.091
Mdm2transformed mouse 3T3 cell double minute 20.090
Nhedc2Na+/H+ exchanger domain containing 20.085
Fshrfollicle stimulating hormone receptor0.082
Syn2synapsin II0.082
Lrp1low density lipoprotein receptor-related protein 10.076
Shc3src homology 2 domain-containing transforming protein C30.075
Gpr83G protein-coupled receptor 830.075
Cd160CD160 antigen0.074
Slc16a8solute carrier family 16 (monocarboxylic acid transporters), member 80.073
Cav1caveolin 1, caveolae protein0.073
Gsx1GS homeobox 10.072
Sstr1somatostatin receptor 10.071
Ptgdsprostaglandin D2 synthase (brain)0.070
Syt10synaptotagmin X0.069
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.069
Cdkn2acyclin-dependent kinase inhibitor 2A0.068
Adra2cadrenergic receptor, alpha 2c0.068
Klk4kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)0.068
Chrm1cholinergic receptor, muscarinic 1, CNS0.067
Tgfbr3transforming growth factor, beta receptor III0.067
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.067
Fam164cfamily with sequence similarity 164, member C0.066
Avparginine vasopressin0.065
Gng4guanine nucleotide binding protein (G protein), gamma 40.065
Cyp11b1cytochrome P450, family 11, subfamily b, polypeptide 10.065
Kcnj9potassium inwardly-rectifying channel, subfamily J, member 90.064
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.457
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.394
Ifitm3interferon induced transmembrane protein 30.389
Dynll1dynein light chain LC8-type 10.308
Cntfrciliary neurotrophic factor receptor0.205
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.200
Adora2aadenosine A2a receptor0.191
Egr4early growth response 40.121
Ncr1natural cytotoxicity triggering receptor 10.119
Cysscystatin S0.108
Aqp2aquaporin 2 (collecting duct)0.102
Pgam1phosphoglycerate mutase 1 (brain)0.101
Chrm4cholinergic receptor, muscarinic 40.100
Calm1calmodulin 10.096
Cckarcholecystokinin A receptor0.096
Fgf14fibroblast growth factor 140.094
Prp15proline-rich protein 150.092
Gzmkgranzyme K0.092
Gpr176G protein-coupled receptor 1760.091
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.085
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.080
Cxcl10chemokine (C-X-C motif) ligand 100.080
Gpr6G protein-coupled receptor 60.078
Drd2dopamine receptor D20.078
Glp1rglucagon-like peptide 1 receptor0.076
Kcna5potassium voltage-gated channel, shaker-related subfamily, member 50.069
RGD1560784similar to RIKEN cDNA B630019K060.069
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.068
Adam10ADAM metallopeptidase domain 100.068
Olr1078olfactory receptor 10780.067
Igf2insulin-like growth factor 20.066
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.065
Cd40lgCD40 ligand0.061
Hrh3histamine receptor H30.059
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.059
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.058
Crhr1corticotropin releasing hormone receptor 10.058
Cyp27b1cytochrome P450, family 27, subfamily b, polypeptide 10.057
Gpr88G-protein coupled receptor 880.055
Mapk4mitogen-activated protein kinase 40.054
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.054
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.054
Csf1colony stimulating factor 1 (macrophage)0.053
Cmklr1chemokine-like receptor 10.053
Guk1guanylate kinase 10.053
Olr416olfactory receptor 4160.052
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.051
Cckbrcholecystokinin B receptor0.051
Atp2b4ATPase, Ca++ transporting, plasma membrane 40.050
Vipr2vasoactive intestinal peptide receptor 20.050
Dad1defender against cell death 10.050
Adra2aadrenergic, alpha-2A-, receptor0.049
Ptp4a2protein tyrosine phosphatase 4a20.049
Amhanti-Mullerian hormone0.048
Cx3cr1chemokine (C-X3-C motif) receptor 10.048
Stmn4stathmin-like 40.047
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.047
Testintestin gene0.047
Col10a1collagen, type X, alpha 10.046
Nf2neurofibromin 2 (merlin)0.045
Adora1adenosine A1 receptor0.045
LOC100360919Immunoglobulin lambda-like polypeptide 1-like0.045
Mcpt1mast cell protease 10.045
Lrpap1low density lipoprotein receptor-related protein associated protein 10.045
Tacr2tachykinin receptor 20.045
Tpcr12putative olfactory receptor0.044
F2rl1coagulation factor II (thrombin) receptor-like 10.044
Edn1endothelin 10.043
Odf4outer dense fiber of sperm tails 40.043
Cd14CD14 molecule0.043
Phkg1phosphorylase kinase, gamma 10.042
Cd63Cd63 molecule0.042
Sgp158proline-rich glycoprotein (sgp158)0.040
Fam65afamily with sequence similarity 65, member A0.040
Gja3gap junction protein, alpha 30.039
Oxtroxytocin receptor0.039
Gfra1GDNF family receptor alpha 10.039
Cfdcomplement factor D (adipsin)0.039
Nme1non-metastatic cells 1, protein (NM23A) expressed in0.039
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.039
Adrb1adrenergic, beta-1-, receptor0.038
Mchr1melanin-concentrating hormone receptor 10.038
Pfkfb46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 40.038
Kalrnkalirin, RhoGEF kinase0.037
Shox2short stature homeobox 20.037
Prl2a1Prolactin family 2, subfamily a, member 10.037
Crhcorticotropin releasing hormone0.037
Ccl2chemokine (C-C motif) ligand 20.036
Fgf2fibroblast growth factor 20.036
Entpd3ectonucleoside triphosphate diphosphohydrolase 30.035
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism