The network for 'cell aggregation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell aggregation

The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.

Danio rerio
NameDescriptionProbabilityFunc Analog Organism
col2a1acollagen type II, alpha-1a0.470
myod1myogenic differentiation 10.335
ptch2patched 20.163
gscgoosecoid0.159
col27a1acollagen, type XXVII, alpha 1a0.113
pea3ETS-domain transcription factor pea30.083
tgfb3transforming growth factor, beta 30.082
fabp2fatty acid binding protein 2, intestinal0.062
col11a2collagen type XI alpha-20.061
loxl3blysyl oxidase-like 3b0.059
fn1fibronectin 10.057
nadl1.1neural adhesion molecule L1.10.055
sulf1sulfatase 10.052
trpv1transient receptor potential cation channel subfamily V member 10.052
lect1leukocyte cell derived chemotaxin 10.051
wnt9awingless-type MMTV integration site family, member 9A0.050
osr2odd-skipped related 2 (Drosophila)0.048
sox10SRY-box containing gene 100.042
myogmyogenin0.041
jam2bjunctional adhesion molecule 2b0.040
gdf6agrowth differentiation factor 6a0.040
snai1asnail homolog 1a (Drosophila)0.037
col1a2collagen, type I, alpha 20.037
col10a1collagen, type X, alpha 10.036
hapln1ahyaluronan and proteoglycan link protein 1a0.036
jam2ajunctional adhesion molecule 2a0.036
sdprbserum deprivation response b0.035
fgf8afibroblast growth factor 8 a0.035
dspadesmoplakin a0.035
barx1BarH-like homeobox 10.035
utxubiquitously transcribed tetratricopeptide repeat, X chromosome0.034
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.034
dsg2desmoglein 20.033
foxa3forkhead box A30.032
tcf21transcription factor 210.031
bmp4bone morphogenetic protein 40.029
castcalpastatin0.029
zgc:92429zgc:924290.029
cart1cartilage paired-class homeoprotein 10.029
slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.028
hand2heart and neural crest derivatives expressed transcript 20.027
npntnephronectin0.027
mychmyelocytomatosis oncogene homolog0.027
ptch1patched 10.027
aldh1a2aldehyde dehydrogenase 1 family, member A20.026
snai2snail homolog 2 (Drosophila)0.026
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.025
dab2disabled homolog 2 (Drosophila)0.023
slc4a2asolute carrier family 4, anion exchanger, member 2a0.023
lmo4aLIM domain only 4a0.023
epycepiphycan0.023
twist2twist20.023
lbx2ladybird homeobox homolog 2 (Drosophila)0.022
trpv4transient receptor potential cation channel, subfamily V, member 40.021
shhasonic hedgehog a0.021
myf5myogenic factor 50.020
actc1bactin, alpha, cardiac muscle 1b0.020
osr1odd-skipped related 1 (Drosophila)0.020
efemp2EGF-containing fibulin-like extracellular matrix protein 20.020
zgc:85866zgc:858660.019
sema3absemaphorin 3ab0.019
bmperBMP binding endothelial regulator0.019
LOC556647GDNF family receptor alpha-4-like0.019
pdzrn3PDZ domain containing RING finger 3 and PDZ domain containing ring finger 30.019
meox1mesenchyme homeobox 10.018
crb2acrumbs homolog 2a0.018
slc3a2solute carrier family 3, member 20.018
rapsnreceptor-associated protein of the synapse, 43kD0.018
p2rx2purinergic receptor P2X, ligand-gated ion channel, 20.018
igf2ainsulin-like growth factor 2a0.018
col11a1bcollagen type XI alpha-1b and collagen, type XI, alpha 1b0.017
nrp1bneuropilin 1b0.017
apex2APEX nuclease (apurinic/apyrimidinic endonuclease) 20.017
dlcdeltaC0.016
gcgaglucagon a and glucagon a-like0.016
col27a1bcollagen, type XXVII, alpha 1b0.016
notch2notch homolog 20.016
esr1estrogen receptor 10.016
si:ch211-9d9.3si:ch211-9d9.30.016
bmp3bone morphogenetic protein 30.016
zgc:85838zgc:858380.016
ftr82finTRIM family, member 820.016
mkxamohawk homeobox a0.016
tfebtranscription factor EB0.016
dusp6dual specificity phosphatase 60.016
si:dkey-261h17.1si:dkey-261h17.10.016
plod1aprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a0.015
hoxc8ahomeo box C8a0.015
acanaaggrecan a0.015
leprleptin receptor0.015
crip2cysteine-rich protein 20.015
wlswntless homolog (Drosophila)0.015
prdm16PR domain containing 160.014
nrf1nuclear respiratory factor 10.014
pthlhparathyroid hormone-like hormone0.014
fzd2frizzled homolog 20.014
rasl11bRAS-like, family 11, member B0.014
or111-1odorant receptor, family D, subfamily 111, member 10.014
mc5rbmelanocortin 5b receptor0.014
adam23aa disintegrin and metallopeptidase domain 23a0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.998
MAPK3mitogen-activated protein kinase 30.983
PKD2polycystic kidney disease 2 (autosomal dominant)0.964
GDF5growth differentiation factor 50.929
DUSP1dual specificity phosphatase 10.838
CYR61cysteine-rich, angiogenic inducer, 610.782
ZFP36L1zinc finger protein 36, C3H type-like 10.682
MAPK1mitogen-activated protein kinase 10.679
FGF18fibroblast growth factor 180.665
FGFR2fibroblast growth factor receptor 20.611
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 20.456
PTPRRprotein tyrosine phosphatase, receptor type, R0.445
WNT1wingless-type MMTV integration site family, member 10.311
COL2A1collagen, type II, alpha 10.308
DUSP9dual specificity phosphatase 90.246
MED1mediator complex subunit 10.226
FGF1fibroblast growth factor 1 (acidic)0.202
FOXF2forkhead box F20.169
WIF1WNT inhibitory factor 10.159
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.156
BMP2bone morphogenetic protein 20.148
MKNK2MAP kinase interacting serine/threonine kinase 20.147
AQP5aquaporin 50.144
FGF10fibroblast growth factor 100.135
MMP11matrix metallopeptidase 11 (stromelysin 3)0.128
SFRP1secreted frizzled-related protein 10.127
FGF4fibroblast growth factor 40.120
BMP4bone morphogenetic protein 40.120
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.118
MKNK1MAP kinase interacting serine/threonine kinase 10.114
NPHP1nephronophthisis 1 (juvenile)0.112
HYAL1hyaluronoglucosaminidase 10.107
MAPK11mitogen-activated protein kinase 110.105
FGF3fibroblast growth factor 30.101
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.098
CRLF1cytokine receptor-like factor 10.097
FGFR3fibroblast growth factor receptor 30.089
WNT10Awingless-type MMTV integration site family, member 10A0.086
DUSP16dual specificity phosphatase 160.081
LBX1ladybird homeobox 10.079
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.079
FN1fibronectin 10.079
PRPHperipherin0.079
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.077
HRhairless homolog (mouse)0.076
WNT11wingless-type MMTV integration site family, member 110.075
IHHIndian hedgehog0.075
FOXL1forkhead box L10.071
FGF19fibroblast growth factor 190.070
SOX11SRY (sex determining region Y)-box 110.069
NCOA6nuclear receptor coactivator 60.069
COL9A2collagen, type IX, alpha 20.069
EPHB3EPH receptor B30.068
C1QL1complement component 1, q subcomponent-like 10.068
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.066
DUSP3dual specificity phosphatase 30.066
NXPH3neurexophilin 30.062
FGF8fibroblast growth factor 8 (androgen-induced)0.062
PTPRJprotein tyrosine phosphatase, receptor type, J0.062
HOXD9homeobox D90.061
ENTPD2ectonucleoside triphosphate diphosphohydrolase 20.060
COL10A1collagen, type X, alpha 10.058
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.058
HSPG2heparan sulfate proteoglycan 20.054
EXOC3L2exocyst complex component 3-like 20.054
PRELPproline/arginine-rich end leucine-rich repeat protein0.054
CDX1caudal type homeobox 10.053
BMP7bone morphogenetic protein 70.053
BMP8Abone morphogenetic protein 8a0.053
FOXJ1forkhead box J10.052
GRPgastrin-releasing peptide0.052
COL1A1collagen, type I, alpha 10.051
MAP2K1mitogen-activated protein kinase kinase 10.050
CUX1cut-like homeobox 10.050
HES2hairy and enhancer of split 2 (Drosophila)0.049
WNT7Awingless-type MMTV integration site family, member 7A0.049
NGFRnerve growth factor receptor0.049
HOXB1homeobox B10.048
SIX2SIX homeobox 20.048
FEVFEV (ETS oncogene family)0.048
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 30.047
SMOsmoothened homolog (Drosophila)0.047
ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)0.047
COL11A1collagen, type XI, alpha 10.047
PAX8paired box 80.046
HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 60.046
POU3F1POU class 3 homeobox 10.046
MAPK9mitogen-activated protein kinase 90.046
PXNpaxillin0.045
HOXD13homeobox D130.044
GDF10growth differentiation factor 100.043
CHST3carbohydrate (chondroitin 6) sulfotransferase 30.042
INHBBinhibin, beta B0.042
GATA1GATA binding protein 1 (globin transcription factor 1)0.042
FBLN1fibulin 10.042
PAX1paired box 10.042
NKD2naked cuticle homolog 2 (Drosophila)0.042
FZD8frizzled homolog 8 (Drosophila)0.042
RAXretina and anterior neural fold homeobox0.041
HOXD1homeobox D10.041
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tgfb2transforming growth factor, beta 20.991
Pax3paired box gene 30.984
Col1a1collagen, type I, alpha 10.982
Meox2mesenchyme homeobox 20.981
Fbn1fibrillin 10.944
Tgfbr2transforming growth factor, beta receptor II0.895
Trp53transformation related protein 530.887
Pkd1polycystic kidney disease 1 homolog0.884
Ptenphosphatase and tensin homolog0.821
Fgf10fibroblast growth factor 100.776
Gli2GLI-Kruppel family member GLI20.702
Pax7paired box gene 70.700
Mapk14mitogen-activated protein kinase 140.698
Gli3GLI-Kruppel family member GLI30.682
Shhsonic hedgehog0.662
Pitx2paired-like homeodomain transcription factor 20.637
Foxc1forkhead box C10.625
Loxlysyl oxidase0.484
Engendoglin0.481
Sox9SRY-box containing gene 90.458
Fgfr3fibroblast growth factor receptor 30.449
Rargretinoic acid receptor, gamma0.411
Twist2twist homolog 2 (Drosophila)0.386
Col6a3collagen, type VI, alpha 30.382
Rararetinoic acid receptor, alpha0.376
Gata4GATA binding protein 40.340
Prrx1paired related homeobox 10.332
Bmp4bone morphogenetic protein 40.327
Hspg2perlecan (heparan sulfate proteoglycan 2)0.310
Pax2paired box gene 20.310
Fgf8fibroblast growth factor 80.297
Nf1neurofibromatosis 10.295
Pthlhparathyroid hormone-like peptide0.276
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.263
Acvr1activin A receptor, type 10.252
Rarbretinoic acid receptor, beta0.236
Pax6paired box gene 60.229
Rxraretinoid X receptor alpha0.220
Tbx1T-box 10.216
Bmpr1abone morphogenetic protein receptor, type 1A0.212
Fgfr2fibroblast growth factor receptor 20.207
Ptpn11protein tyrosine phosphatase, non-receptor type 110.201
Sox11SRY-box containing gene 110.195
Smad3MAD homolog 3 (Drosophila)0.179
Prrx2paired related homeobox 20.177
Hoxd13homeobox D130.172
Col6a2collagen, type VI, alpha 20.165
Hhexhematopoietically expressed homeobox0.143
Col11a1collagen, type XI, alpha 10.143
Zeb1zinc finger E-box binding homeobox 10.143
Isl1ISL1 transcription factor, LIM/homeodomain0.137
Atoh7atonal homolog 7 (Drosophila)0.129
Nodalnodal0.127
Twist1twist homolog 1 (Drosophila)0.123
Ntf3neurotrophin 30.121
Col6a1collagen, type VI, alpha 10.118
Fstfollistatin0.115
Capn6calpain 60.113
Gdf11growth differentiation factor 110.112
Bdnfbrain derived neurotrophic factor0.112
Ptx3pentraxin related gene0.111
Egfrepidermal growth factor receptor0.106
Ror2receptor tyrosine kinase-like orphan receptor 20.106
Sox4SRY-box containing gene 40.105
Lmx1aLIM homeobox transcription factor 1 alpha0.104
Zfpm2zinc finger protein, multitype 20.101
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.095
Btbd17BTB (POZ) domain containing 170.092
Tgfbr1transforming growth factor, beta receptor I0.090
Col5a1collagen, type V, alpha 10.089
Tll1tolloid-like0.086
Foxc2forkhead box C20.084
Tbx10T-box 100.082
Nr3c1nuclear receptor subfamily 3, group C, member 10.081
Acanaggrecan0.079
Sox17SRY-box containing gene 170.076
Thbs1thrombospondin 10.068
Elnelastin0.068
Bcl6bB-cell CLL/lymphoma 6, member B0.067
Pou3f3POU domain, class 3, transcription factor 30.067
Fstl1follistatin-like 10.066
Robo3roundabout homolog 3 (Drosophila)0.065
Vegfavascular endothelial growth factor A0.065
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.064
Tnctenascin C0.064
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.060
Ednraendothelin receptor type A0.060
Hapln1hyaluronan and proteoglycan link protein 10.059
Creb1cAMP responsive element binding protein 10.057
Kitkit oncogene0.057
Tbx15T-box 150.055
Galgalanin0.055
Col8a1collagen, type VIII, alpha 10.055
Thrbthyroid hormone receptor beta0.055
Nos3nitric oxide synthase 3, endothelial cell0.053
Tefthyrotroph embryonic factor0.052
Meox1mesenchyme homeobox 10.051
Dhhdesert hedgehog0.049
Col2a1collagen, type II, alpha 10.048
Csf1colony stimulating factor 1 (macrophage)0.047
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
FLO10Flo10p0.981
FIG2Fig2p0.875
MUC1Muc1p0.713
FLO9Flo9p0.668
FLO5Flo5p0.605
FLO1Flo1p0.384
CWP2Cwp2p0.267
MSS11Mss11p0.255
FLO8Flo8p0.244
SFL1Sfl1p0.091
AGA1Aga1p0.059
FIG1Fig1p0.045
AGA2Aga2p0.041
YKR104Whypothetical protein0.033
SCW4Scw4p0.030
YLR264C-Ahypothetical protein0.029
SAG1Sag1p0.027
SRD1Srd1p0.026
TEC1Tec1p0.026
YOL038C-Ahypothetical protein0.022
LEU2Leu2p0.022
CUP1-1Cup1-1p0.021
YLR162Whypothetical protein0.021
ARP10Arp10p0.020
ZPS1Zps1p0.020
YLR040Chypothetical protein0.020
SPL2Spl2p0.019
HXT3Hxt3p0.018
MER1Mer1p0.018
PHD1Phd1p0.018
YLR042Chypothetical protein0.018
TPI1Tpi1p0.017
YPR157Whypothetical protein0.017
ATP6Atp6p0.017
YMR317Whypothetical protein0.016
YBR013Chypothetical protein0.016
ARG8Arg8p0.015
YAL064Whypothetical protein0.015
AUA1Aua1p0.015
FKS3Fks3p0.014
HPF1Hpf1p0.014
FMT1Fmt1p0.014
MF(ALPHA)2Mf(alpha)2p0.014
OPT2Opt2p0.013
BSC1Bsc1p0.013
CPD1Cpd1p0.013
YAL037C-Ahypothetical protein0.013
YOL013W-Ahypothetical protein0.013
SWC7Swc7p0.013
IZH4Izh4p0.013
YIL151Chypothetical protein0.013
PTR2Ptr2p0.013
BDS1Bds1p0.012
SKS1Sks1p0.012
YAR068Whypothetical protein0.012
TIR3Tir3p0.012
MFA2Mfa2p0.012
IMA5Ima5p0.012
MFA1Mfa1p0.012
YPL067Chypothetical protein0.012
DIC1Dic1p0.012
SCM4Scm4p0.011
ADH2Adh2p0.011
UPS3Ups3p0.011
YIR035Chypothetical protein0.011
DUR1,2Dur1,2p0.011
YPR096Chypothetical protein0.011
TDH3Tdh3p0.011
RNP1Rnp1p0.011
YGL006W-Ahypothetical protein0.011
CRP1Crp1p0.011
YAL065Chypothetical protein0.011
YNL033Whypothetical protein0.010
YAR066Whypothetical protein0.010
YIR042Chypothetical protein0.010
NFT1Nft1p0.010
YKR075Chypothetical protein0.010
YJL107Chypothetical protein0.010
YDR034C-Ahypothetical protein0.010
CHA1Cha1p0.010
YBL029Whypothetical protein0.010