The network for 'mitotic metaphase plate congression' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitotic metaphase plate congression

The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.

NameDescriptionProbabilityFunc Analog Organism
aurkbaurora kinase B0.331
plk1polo-like kinase 1 (Drosophila)0.265
ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.204
tacc3transforming, acidic coiled-coil containing protein 30.199
ccna2cyclin A20.185
cdc20cell division cycle 20 homolog0.184
si:ch211-69g19.2si:ch211-69g19.20.170
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.164
kif11kinesin family member 110.161
kif23kinesin family member 230.137
zgc:56200zgc:562000.119
ncapd2non-SMC condensin I complex, subunit D20.099
skp2S-phase kinase-associated protein 2 (p45)0.092
ccnb2cyclin B20.082
nusap1nucleolar and spindle associated protein 10.077
smc4structural maintenance of chromosomes 40.069
zgc:92661zgc:926610.054
si:ch211-244o22.2si:ch211-244o22.20.052
nuf2NUF2, NDC80 kinetochore complex component, homolog0.051
cep55lcentrosomal protein 55 like0.050
gins3GINS complex subunit 30.049
sass6spindle assembly 6 homolog (C. elegans)0.044
cdca8cell division cycle associated 80.042
rrm1ribonucleotide reductase M1 polypeptide0.039
zgc:174506zgc:1745060.039
zgc:110113zgc:1101130.038
cul1acullin 1a0.036
melkmaternal embryonic leucine zipper kinase0.036
ttkttk protein kinase0.035
dtldenticleless homolog (Drosophila)0.035
ccnb1cyclin B10.034
polr2bpolymerase (RNA) II (DNA directed) polypeptide B0.034
cdt1chromatin licensing and DNA replication factor 10.033
fen1flap structure-specific endonuclease 10.033
hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.033
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.032
slbpstem-loop binding protein0.031
hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.031
g2e3G2/M-phase specific E3 ubiquitin ligase0.031
zfrzinc finger RNA binding protein0.030
surf6surfeit 60.030
LOC100536090targeting protein for Xklp2-B-like0.030
cdk1cyclin-dependent kinase 10.030
smc2structural maintenance of chromosomes 20.029
wdhd1WD repeat and HMG-box DNA binding protein 10.028
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.028
si:dkey-9k8.1si:dkey-9k8.10.027
atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.027
aurkaaurora kinase A0.027
bucbucky ball0.026
depdc1aDEP domain containing 1a0.025
dnmt1DNA (cytosine-5-)-methyltransferase 10.024
rnf40ring finger protein 400.024
zgc:92194zgc:921940.024
kidins220bkinase D-interacting substrate of 220b0.023
gins1GINS complex subunit 1 (Psf1 homolog)0.022
mosv-mos Moloney murine sarcoma viral oncogene homolog0.022
pold1polymerase (DNA directed), delta 1, catalytic subunit0.022
nod1nucleotide-binding oligomerization domain containing 10.022
pspc1paraspeckle component 10.022
dnaja2lDnaJ (Hsp40) homolog, subfamily A, member 2, like0.021
shcbp1SHC SH2-domain binding protein 10.021
mcm4MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)0.021
birc5abaculoviral IAP repeat-containing 5a0.021
si:dkey-91i17.1si:dkey-91i17.10.020
LOC557072caspase recruitment domain-containing protein 11-like0.020
wu:fi04f09wu:fi04f090.019
si:ch211-215h6.2si:ch211-215h6.20.019
zgc:162965zgc:1629650.019
ddx49DEAD (Asp-Glu-Ala-Asp) box polypeptide 490.018
ankhd1ankyrin repeat and KH domain containing 10.018
si:ch211-197n10.2si:ch211-197n10.20.018
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.018
zgc:92139zgc:921390.018
spna2spectrin alpha 20.017
orc1origin recognition complex, subunit 10.017
LOC100330645heterogeneous nuclear ribonucleoprotein U-like protein 1-like0.017
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.017
im:7163548im:71635480.017
si:dkey-181m9.9si:dkey-181m9.90.016
ubinataxin-1 ubiquitin-like interacting protein0.016
senp3aSUMO1/sentrin/SMT3 specific peptidase 3a0.016
tubg1tubulin, gamma 10.016
dhfrdihydrofolate reductase0.016
zgc:152925zgc:1529250.016
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.016
sart3squamous cell carcinoma antigen recognised by T cells 30.015
rtkn2rhotekin 20.015
b4galt6UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 60.015
zgc:110540zgc:1105400.015
ncapgnon-SMC condensin I complex, subunit G0.015
atf4b2activating transcription factor 4b20.015
ptenaphosphatase and tensin homolog A0.015
srsf4serine/arginine-rich splicing factor 40.015
cse1lchromosome segregation 1-like (S. cerevisiae)0.014
wu:fj39b01wu:fj39b010.014
acin1aapoptotic chromatin condensation inducer 1a0.014
zgc:153910zgc:1539100.014
bc2putative breast adenocarcinoma marker0.014
kdm5clysine (K)-specific demethylase 5C0.013
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ubxn-1Protein UBXN-10.459
klp-19Protein KLP-190.218
T20F5.7Protein T20F5.70.144
npp-11Protein NPP-110.144
mcm-7Protein MCM-70.139
aspm-1Protein ASPM-10.100
CELE_Y53F4B.9Protein Y53F4B.90.089
rnr-1Protein RNR-10.073
spd-1Protein SPD-10.069
hcp-2Protein HCP-20.068
ZK1127.5Protein ZK1127.50.061
bub-1Protein BUB-10.052
cyb-2.2Protein CYB-2.20.051
mcm-2Protein MCM-20.043
cdl-1Protein CDL-10.038
Y4C6B.1Protein Y4C6B.10.036
hsp-1Protein HSP-10.035
spdl-1Protein SPDL-10.034
scc-1Protein SCC-10.032
gpr-1Protein GPR-10.032
sgo-1Protein SGO-10.031
egg-3Protein EGG-30.029
let-858Protein LET-8580.029
puf-6Protein PUF-60.024
CELE_B0238.9Protein B0238.90.023
lpd-7Protein LPD-70.022
zen-4Protein ZEN-40.022
fzy-1Protein FZY-10.022
dsh-2Protein DSH-20.021
prp-8Protein PRP-80.021
hcp-1Protein HCP-10.021
knl-1Protein KNL-10.020
CELE_C01G6.3Protein C01G6.30.019
gyg-2Protein GYG-20.019
bmk-1Protein BMK-10.019
cul-1Protein CUL-10.019
CELE_C39E9.12Protein C39E9.120.018
cyk-4Protein CYK-40.017
CELE_W03F9.10Protein W03F9.100.016
lin-13Protein LIN-130.016
klp-7Protein KLP-70.016
rsp-1Protein RSP-10.015
C44B9.3Protein C44B9.30.015
T19H12.2Protein T19H12.20.015
pie-1Protein PIE-10.015
pcn-1Protein PCN-10.015
R05D3.2Protein R05D3.20.014
cki-2Protein CKI-20.013
cyb-1Protein CYB-10.013
H43I07.2Protein H43I07.20.013
R05G6.4Protein R05G6.40.013
rfc-2Protein RFC-20.013
cgh-1Protein CGH-10.013
mel-28Protein MEL-280.013
mrg-1Protein MRG-10.012
cdc-37Protein CDC-370.012
hcp-6Protein HCP-60.012
top-2Protein TOP-20.012
ztf-18Protein ZTF-180.012
F25B5.2Protein F25B5.20.012
ani-1Protein ANI-10.011
CELE_C24H12.4Protein C24H12.40.011
ZC434.8Protein ZC434.80.011
CELE_Y39B6A.42Protein Y39B6A.420.011
hcp-4Protein HCP-40.010
CELE_Y23H5A.3Protein Y23H5A.30.010
air-2Protein AIR-20.010
tac-1Protein TAC-10.010
csn-1Protein CSN-10.010
ung-1Protein UNG-10.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Nuf2CG8902 gene product from transcript CG8902-RA0.981
Mis12CG18156 gene product from transcript CG18156-RA0.976
Spc25CG7242 gene product from transcript CG7242-RA0.970
Kmn1kinetochore Mis12-Ndc80 network component 10.942
cmetCENP-meta0.894
Ndc80CG9938 gene product from transcript CG9938-RA0.809
Cenp-CCG31258 gene product from transcript CG31258-RA0.593
cidcentromere identifier0.555
marsCG17064 gene product from transcript CG17064-RB0.275
ncdnon-claret disjunctional0.262
aslasterless0.193
msd1mitotic spindle density 10.168
Spc105RSpc105-related0.163
Mcm10Sensitized chromosome inheritance modifier 190.074
Lis-1Lissencephaly-10.057
cavcaravaggio0.053
Poc1Proteome of centrioles 10.050
vtdverthandi0.045
Nnf1aCG13434 gene product from transcript CG13434-RA0.044
gammaTub37Cgamma-Tubulin at 37C0.039
toctoucan0.038
dpadisc proliferation abnormal0.034
cdc23CG2508 gene product from transcript CG2508-RA0.031
pimpimples0.029
DetDeterin0.028
Cks30ACyclin-dependent kinase subunit 30A0.025
Nnf1bCG31658 gene product from transcript CG31658-RA0.024
Cap-GCG34438 gene product from transcript CG34438-RF0.024
pitaCG3941 gene product from transcript CG3941-RA0.023
Orc2Origin recognition complex subunit 20.023
larpLa related protein0.021
cnncentrosomin0.018
Nek2CG17256 gene product from transcript CG17256-RA0.014
lkb1CG9374 gene product from transcript CG9374-RJ0.014
Orc5Origin recognition complex subunit 50.013
Cp110CG14617 gene product from transcript CG14617-RB0.013
CG4680CG4680 gene product from transcript CG4680-RA0.013
Cdc27CG8610 gene product from transcript CG8610-RA0.012
IncenpInner centromere protein0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.786
RBL1retinoblastoma-like 1 (p107)0.542
CCNA2cyclin A20.453
CDK2cyclin-dependent kinase 20.410
CCNB1cyclin B10.388
NUP133nucleoporin 133kDa0.253
CDC27cell division cycle 27 homolog (S. cerevisiae)0.199
CDC20cell division cycle 20 homolog (S. cerevisiae)0.171
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.132
INCENPinner centromere protein antigens 135/155kDa0.122
ANAPC5anaphase promoting complex subunit 50.118
RB1retinoblastoma 10.094
RBBP8retinoblastoma binding protein 80.083
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.080
CBX5chromobox homolog 50.070
KIF1Bkinesin family member 1B0.062
NUP107nucleoporin 107kDa0.047
NEK2NIMA (never in mitosis gene a)-related kinase 20.046
PHAXphosphorylated adaptor for RNA export0.044
DLGAP5discs, large (Drosophila) homolog-associated protein 50.039
RBL2retinoblastoma-like 2 (p130)0.035
TFDP1transcription factor Dp-10.035
RAD21RAD21 homolog (S. pombe)0.034
KIF20Akinesin family member 20A0.033
FBXO5F-box protein 50.033
AURKBaurora kinase B0.031
UBE4Bubiquitination factor E4B (UFD2 homolog, yeast)0.029
CDK1cyclin-dependent kinase 10.028
CKS2CDC28 protein kinase regulatory subunit 20.027
VCPvalosin containing protein0.027
RACGAP1Rac GTPase activating protein 10.027
AKAP9A kinase (PRKA) anchor protein (yotiao) 90.026
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.026
STAG1stromal antigen 10.026
SGOL2shugoshin-like 2 (S. pombe)0.025
CENPEcentromere protein E, 312kDa0.024
BIRC5baculoviral IAP repeat containing 50.024
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.023
CTPSCTP synthase0.022
MDM4Mdm4 p53 binding protein homolog (mouse)0.022
CDCA8cell division cycle associated 80.021
ANAPC1anaphase promoting complex subunit 10.021
CCNE2cyclin E20.021
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.020
CKS1BCDC28 protein kinase regulatory subunit 1B0.020
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.020
CDC16cell division cycle 16 homolog (S. cerevisiae)0.019
ANAPC4anaphase promoting complex subunit 40.019
ECT2epithelial cell transforming sequence 2 oncogene0.018
AHCTF1AT hook containing transcription factor 10.018
LIN54lin-54 homolog (C. elegans)0.017
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.017
UBXN2AUBX domain protein 2A0.017
TTKTTK protein kinase0.017
ATXN3ataxin 30.017
SGOL1shugoshin-like 1 (S. pombe)0.017
LIN9lin-9 homolog (C. elegans)0.015
AMFRautocrine motility factor receptor0.015
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.015
KIF23kinesin family member 230.015
ORC2origin recognition complex, subunit 20.015
SYVN1synovial apoptosis inhibitor 1, synoviolin0.015
CKAP5cytoskeleton associated protein 50.015
E2F1E2F transcription factor 10.015
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.013
RRP1Bribosomal RNA processing 1 homolog B (S. cerevisiae)0.013
SKP2S-phase kinase-associated protein 2 (p45)0.013
UFD1Lubiquitin fusion degradation 1 like (yeast)0.012
KIF11kinesin family member 110.012
E2F5E2F transcription factor 5, p130-binding0.012
E2F4E2F transcription factor 4, p107/p130-binding0.012
UHRF2ubiquitin-like with PHD and ring finger domains 20.012
LYARLy1 antibody reactive homolog (mouse)0.012
CCNE1cyclin E10.012
CENPQcentromere protein Q0.011
CDKN3cyclin-dependent kinase inhibitor 30.011
C13orf34chromosome 13 open reading frame 340.011
RSL1D1ribosomal L1 domain containing 10.011
PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 80.011
PAFAH1B2platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)0.011
YTHDC2YTH domain containing 20.011
PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.011
GPSM2G-protein signaling modulator 20.011
WDR67WD repeat domain 670.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MPS1Mps1p0.453
MTW1Mtw1p0.180
NUF2Nuf2p0.129
SLK19Slk19p0.119
CLB1Clb1p0.119
MIF2Mif2p0.109
KIP1Kip1p0.109
NNF1Nnf1p0.106
SMC4Smc4p0.094
DSN1Dsn1p0.089
TID3Tid3p0.086
SPC24Spc24p0.079
CDC16Cdc16p0.071
NSL1Nsl1p0.070
MAD2Mad2p0.068
CDC28Cdc28p0.061
IPL1Ipl1p0.061
VIK1Vik1p0.058
CDC20Cdc20p0.049
BRN1Brn1p0.047
NBL1Nbl1p0.046
SLI15Sli15p0.046
CIN8Cin8p0.046
SPC105Spc105p0.043
SMC2Smc2p0.043
CLB4Clb4p0.037
CTF3Ctf3p0.037
NUP157Nup157p0.037
CLB3Clb3p0.036
KAR3Kar3p0.032
CDC27Cdc27p0.032
STU1Stu1p0.030
STU2Stu2p0.029
KAR9Kar9p0.028
DYN3Dyn3p0.027
UFD2Ufd2p0.027
PTI1Pti1p0.026
SGO1Sgo1p0.026
SIC1Sic1p0.025
KEL1Kel1p0.023
CLB6Clb6p0.023
KIN3Kin3p0.022
SMC5Smc5p0.021
DAM1Dam1p0.021
SPC25Spc25p0.020
SRD1Srd1p0.019
OKP1Okp1p0.018
ESP1Esp1p0.018
CDC26Cdc26p0.018
ARG8Arg8p0.017
SCM3Scm3p0.017
YLR162Whypothetical protein0.017
YLR264C-Ahypothetical protein0.017
CSE4Cse4p0.016
PDS1Pds1p0.016
CDC48Cdc48p0.016
YOL038C-Ahypothetical protein0.016
LEU2Leu2p0.016
SHE1She1p0.016
ARP10Arp10p0.015
PPH21Pph21p0.015
CLB5Clb5p0.015
MER1Mer1p0.014
YIL151Chypothetical protein0.014
CKS1Cks1p0.014
ECO1Eco1p0.013
URA3Ura3p0.013
YJL107Chypothetical protein0.013
TAH11Tah11p0.013
DOC1Doc1p0.013
MAD1Mad1p0.013
SPL2Spl2p0.012
CRP1Crp1p0.012
YAR068Whypothetical protein0.012
BFA1Bfa1p0.012
MMS21Mms21p0.012
YNL058Chypothetical protein0.012
CIK1Cik1p0.012
YIR035Chypothetical protein0.012
YBR013Chypothetical protein0.012
YPR157Whypothetical protein0.012
ATP6Atp6p0.012
ZPS1Zps1p0.012
PRS2Prs2p0.012
HXT3Hxt3p0.011
DCC1Dcc1p0.011
BCK2Bck2p0.011
SPS4Sps4p0.011
KIP2Kip2p0.011
ACM1Acm1p0.011
CHA1Cha1p0.011
NUP49Nup49p0.011
CUP1-1Cup1-1p0.011
YNL155Whypothetical protein0.011
BIK1Bik1p0.011
AUA1Aua1p0.011
ADH2Adh2p0.011
YLR042Chypothetical protein0.010
HPF1Hpf1p0.010
CDC4Cdc4p0.010