The network for 'exocrine system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

exocrine system development

Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.

NameDescriptionProbabilityFunc Analog Organism
hoxb5bhomeo box B5b0.682
kdrlkinase insert domain receptor like0.589
hoxb8ahomeo box B8a0.585
hhiphedgehog interacting protein0.567
hoxc4ahomeo box C4a0.537
evx1even-skipped homeobox 10.500
gdf6agrowth differentiation factor 6a0.473
hoxb6bhomeo box B6b0.473
bocbrother of CDO0.464
foxa1forkhead box A10.457
cdh2cadherin 2, neuronal0.456
pax6bpaired box gene 6b0.389
raraaretinoic acid receptor, alpha a0.376
notch3notch homolog 30.334
ascl1aachaete-scute complex-like 1a (Drosophila)0.325
gyltl1bglycosyltransferase-like 1b0.313
hoxb5ahomeo box B5a0.299
slit3slit (Drosophila) homolog 30.296
tbx2bT-box 2b0.295
hoxc8ahomeo box C8a0.276
hoxa4ahomeo box A4a0.270
itgb1b.2integrin, beta 1b.20.252
ptf1apancreas specific transcription factor, 1a0.250
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.246
fgf8afibroblast growth factor 8 a0.224
fgfr3fibroblast growth factor receptor 30.220
hoxb3ahomeo box B3a0.219
efnb2aephrin B2a0.215
satb2SATB homeobox 20.209
lhx1aLIM homeobox 1a0.193
myod1myogenic differentiation 10.181
myf5myogenic factor 50.178
prox1prospero-related homeobox gene 10.169
axin1axin 10.162
gpr126G protein-coupled receptor 1260.156
nr2f5nuclear receptor subfamily 2, group F, member 50.156
egr2bearly growth response 2b0.156
prdm5PR domain containing 50.150
foxa2forkhead box A20.142
shhasonic hedgehog a0.142
isl1islet10.141
lef1lymphocyte enhancer binding factor 10.141
isl2aislet2a0.131
atoh1aatonal homolog 1a0.130
rad21RAD21 homolog (S. pombe)0.129
tp53tumor protein p530.128
lhx2bLIM homeobox 2b0.126
sox1aSRY-box containing gene 1a0.117
wif1wnt inhibitory factor 10.111
slit2slit (Drosophila) homolog 20.109
robo2roundabout homolog 20.107
twist1atwist1a0.101
csf3rcolony stimulating factor 3 receptor (granulocyte)0.098
pax7apaired box gene 7a0.098
hoxb2ahomeo box B2a0.096
foxa3forkhead box A30.094
wnt2bbwingless-type MMTV integration site family, member 2Bb0.092
jag2jagged 20.091
lamc1laminin, gamma 10.091
igf1rbinsulin-like growth factor 1b receptor0.090
mitfamicrophthalmia-associated transcription factor a0.087
par1paraxis0.086
epb41l5erythrocyte membrane protein band 4.1 like 50.085
itgb1bintegrin, beta 1b0.085
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.084
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.084
pax2apaired box gene 2a0.084
fgfr2fibroblast growth factor receptor 20.083
dlbdeltaB0.083
nrp1aneuropilin 1a0.083
bmp7bbone morphogenetic protein 7b0.083
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.082
itgb1b.1integrin, beta 1b.10.080
znf503zinc finger protein 5030.079
ahctf1AT hook containing transcription factor 10.079
lyzlysozyme0.079
dag1dystroglycan 10.078
fgf3fibroblast growth factor 30.078
fgfr4fibroblast growth factor receptor 40.078
jag1bjagged 1b0.077
dlddeltaD0.075
itgb3bintegrin beta 3b0.074
lmx1b.1LIM homeobox transcription factor 1, beta 10.074
hoxd4ahomeo box D4a0.073
gli2aGLI-Kruppel family member GLI2a0.073
etv2ets variant gene 20.072
robo1roundabout homolog 10.072
ptger4aprostaglandin E receptor 4 (subtype EP4) a0.070
hhexhematopoietically expressed homeobox0.069
myhz2myosin, heavy polypeptide 2, fast muscle specific0.068
dlcdeltaC0.066
nkx3.2NK3 homeobox 20.066
epb4.1l4erythrocyte protein band 4.1-like 40.065
her7hairy and enhancer of split related-70.065
stilTAL1 (SCL) interrupting locus0.065
otpborthopedia homolog b0.064
tgfb3transforming growth factor, beta 30.064
foxp2forkhead box P20.064
fgf10afibroblast growth factor 10a0.063
alpialkaline phosphatase, intestinal0.063
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
tintinman0.946
Rac1CG2248 gene product from transcript CG2248-RA0.929
Btk29ABtk family kinase at 29A0.925
E(spl)Enhancer of split0.916
ushu-shaped0.898
EcREcdysone receptor0.866
Src42ASrc oncogene at 42A0.856
eIF-4aEukaryotic initiation factor 4a0.843
hkbhuckebein0.816
spispitz0.812
eastenhanced adult sensory threshold0.796
NetBNetrin-B0.795
wgwingless0.787
mewmultiple edematous wings0.760
wbwing blister0.758
cicubitus interruptus0.751
dmdiminutive0.747
fzfrizzled0.740
babobaboon0.733
bynbrachyenteron0.729
slp1sloppy paired 10.686
Wnt5Wnt oncogene analog 50.684
slislit0.681
drprdraper0.672
ribribbon0.652
eyaeyes absent0.629
DadDaughters against dpp0.621
tldtolloid0.606
shgshotgun0.604
LanB2Laminin B20.586
atoatonal0.583
Nrx-IVNeurexin IV0.573
EgfrEpidermal growth factor receptor0.566
aopanterior open0.562
sxcsuper sex combs0.550
rapretina aberrant in pattern0.535
hephemipterous0.530
Atg2Autophagy-specific gene 20.524
tkvthickveins0.522
chicchickadee0.518
PvrPDGF- and VEGF-receptor related0.514
fz2frizzled 20.505
fkhfork head0.500
JIL-1CG6297 gene product from transcript CG6297-RA0.497
Stat92ESignal-transducer and activator of transcription protein at 92E0.494
PtpmegCG1228 gene product from transcript CG1228-RD0.478
ttktramtrack0.471
Atg8aAutophagy-specific gene 8a0.469
Ras85DRas oncogene at 85D0.469
HLHmdeltaE(spl) region transcript mdelta0.463
jingCG9397 gene product from transcript CG9397-RI0.462
grimCG4345 gene product from transcript CG4345-RA0.460
LanB1CG7123 gene product from transcript CG7123-RA0.443
snssticks and stones0.432
Atg18Autophagy-specific gene 180.425
oysoysgedart0.419
klarklarsicht0.417
gcmglial cells missing0.405
RelRelish0.401
Or22aOdorant receptor 22a0.390
dshdishevelled0.389
rprreaper0.384
DscamDown syndrome cell adhesion molecule0.381
bskbasket0.380
cnccap-n-collar0.371
roboroundabout0.370
CG14869CG14869 gene product from transcript CG14869-RB0.366
pyrpyramus0.365
C3GCG42328 gene product from transcript CG42328-RC0.362
Gld2CG5732 gene product from transcript CG5732-RA0.359
lealeak0.348
bifbifocal0.346
Gap69CGTPase-activating protein 69C0.337
Atg7Autophagy-specific gene 70.337
A2bp1Ataxin-2 binding protein 10.335
simsingle-minded0.334
lblladybird late0.330
B52CG10851 gene product from transcript CG10851-RB0.330
gsbgooseberry0.329
srpserpent0.329
LIMK1LIM-kinase10.325
otkoff-track0.318
SdcSyndecan0.315
Six4CG3871 gene product from transcript CG3871-RA0.313
gogogolden goal0.310
egeagle0.309
CG7998CG7998 gene product from transcript CG7998-RA0.306
tutlturtle0.298
Traf4TNF-receptor-associated factor 40.297
apapterous0.296
TomTwin of m40.294
Atg1Autophagy-specific gene 10.287
jarjaguar0.286
CG33960CG33960 gene product from transcript CG33960-RB0.286
LysELysozyme E0.281
tlltailless0.278
HGTXCG13475 gene product from transcript CG13475-RB0.277
eveeven skipped0.275
thsthisbe0.271
ik2IkappaB kinase-like 20.263
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.985
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.845
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.607
FGFR2fibroblast growth factor receptor 20.563
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.340
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.233
GRB2growth factor receptor-bound protein 20.212
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.169
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.160
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.159
NRP1neuropilin 10.102
LCKlymphocyte-specific protein tyrosine kinase0.090
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.067
IGF1Rinsulin-like growth factor 1 receptor0.066
FLNAfilamin A, alpha0.064
HSPG2heparan sulfate proteoglycan 20.056
PLECplectin0.056
FGFR1fibroblast growth factor receptor 10.054
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.054
SYKspleen tyrosine kinase0.051
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.050
JAG1jagged 10.050
PTPRJprotein tyrosine phosphatase, receptor type, J0.043
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.043
VEGFAvascular endothelial growth factor A0.040
PTPRCprotein tyrosine phosphatase, receptor type, C0.036
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.036
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.032
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.029
PSEN1presenilin 10.028
NOTCH3notch 30.024
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.024
ENGendoglin0.023
THBS1thrombospondin 10.023
MYO10myosin X0.022
FGF1fibroblast growth factor 1 (acidic)0.021
PDIA3protein disulfide isomerase family A, member 30.020
FN1fibronectin 10.020
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.019
LAMB1laminin, beta 10.018
BLNKB-cell linker0.017
METmet proto-oncogene (hepatocyte growth factor receptor)0.016
GAB1GRB2-associated binding protein 10.016
SOS1son of sevenless homolog 1 (Drosophila)0.016
ARHGAP1Rho GTPase activating protein 10.016
MEOX2mesenchyme homeobox 20.015
NOTCH1notch 10.015
FYNFYN oncogene related to SRC, FGR, YES0.014
LATlinker for activation of T cells0.013
CTNND1catenin (cadherin-associated protein), delta 10.012
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.012
FGF10fibroblast growth factor 100.012
SETD8SET domain containing (lysine methyltransferase) 80.012
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.011
ADAM15ADAM metallopeptidase domain 150.011
PLCG1phospholipase C, gamma 10.011
CDH5cadherin 5, type 2 (vascular endothelium)0.011
FLNBfilamin B, beta0.011
PLAUplasminogen activator, urokinase0.010
TCF4transcription factor 40.010
APPamyloid beta (A4) precursor protein0.010
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Fgfr1fibroblast growth factor receptor 10.993
Gli3GLI-Kruppel family member GLI30.980
Pax3paired box gene 30.972
Tgfb2transforming growth factor, beta 20.957
Pax2paired box gene 20.927
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.924
Ror2receptor tyrosine kinase-like orphan receptor 20.918
Acvr1activin A receptor, type 10.905
Bmp7bone morphogenetic protein 70.878
Fgfr3fibroblast growth factor receptor 30.855
Tnftumor necrosis factor0.849
Shhsonic hedgehog0.804
Vangl2vang-like 2 (van gogh, Drosophila)0.801
Lamc1laminin, gamma 10.799
Trp63transformation related protein 630.758
Robo1roundabout homolog 1 (Drosophila)0.748
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.742
Rargretinoic acid receptor, gamma0.736
Foxc1forkhead box C10.719
Pthlhparathyroid hormone-like peptide0.678
Bmp4bone morphogenetic protein 40.653
Msx2homeobox, msh-like 20.653
Nognoggin0.643
Ddr2discoidin domain receptor family, member 20.611
Fgfr4fibroblast growth factor receptor 40.610
Arandrogen receptor0.604
Hspg2perlecan (heparan sulfate proteoglycan 2)0.601
AxlAXL receptor tyrosine kinase0.593
Foxn1forkhead box N10.593
Foxa2forkhead box A20.588
Ikzf1IKAROS family zinc finger 10.582
Flt4FMS-like tyrosine kinase 40.576
Dlx5distal-less homeobox 50.571
Pax8paired box gene 80.559
Grb10growth factor receptor bound protein 100.546
Csf1colony stimulating factor 1 (macrophage)0.535
Hoxa13homeobox A130.532
Hoxd11homeobox D110.523
Slit3slit homolog 3 (Drosophila)0.503
Nrp1neuropilin 10.496
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.483
Ins2insulin II0.471
Alx4aristaless-like homeobox 40.470
Tbx15T-box 150.468
Mmp9matrix metallopeptidase 90.464
Rararetinoic acid receptor, alpha0.457
Prrx1paired related homeobox 10.456
Cd19CD19 antigen0.455
Kdrkinase insert domain protein receptor0.454
Edarectodysplasin-A receptor0.441
Vangl1vang-like 1 (van gogh, Drosophila)0.437
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.427
Eya1eyes absent 1 homolog (Drosophila)0.421
Msx1homeobox, msh-like 10.416
Inpp5dinositol polyphosphate-5-phosphatase D0.412
Vegfavascular endothelial growth factor A0.381
Nos1nitric oxide synthase 1, neuronal0.365
Hoxa11homeobox A110.358
Prrx2paired related homeobox 20.354
Plauplasminogen activator, urokinase0.351
Notch2Notch gene homolog 2 (Drosophila)0.350
Map3k14mitogen-activated protein kinase kinase kinase 140.348
Ascl1achaete-scute complex homolog 1 (Drosophila)0.348
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.338
Gli2GLI-Kruppel family member GLI20.319
Lamb1laminin B10.318
Tcf21transcription factor 210.295
Zeb1zinc finger E-box binding homeobox 10.279
Itgb3integrin beta 30.274
Prss2protease, serine, 20.269
Meox2mesenchyme homeobox 20.268
Cela3bchymotrypsin-like elastase family, member 3B0.267
Lhx1LIM homeobox protein 10.265
Plcg1phospholipase C, gamma 10.264
Dll1delta-like 1 (Drosophila)0.263
Ptf1apancreas specific transcription factor, 1a0.258
Efnb2ephrin B20.257
Retret proto-oncogene0.257
Ptgs2prostaglandin-endoperoxide synthase 20.256
Pbx1pre B-cell leukemia transcription factor 10.256
Sycnsyncollin0.249
Fgf8fibroblast growth factor 80.242
Edn3endothelin 30.241
EdaraddEDAR (ectodysplasin-A receptor)-associated death domain0.241
Twist2twist homolog 2 (Drosophila)0.239
Tbx1T-box 10.232
Tbx2T-box 20.230
Ednraendothelin receptor type A0.230
Myod1myogenic differentiation 10.223
Mrc2mannose receptor, C type 20.220
Sox11SRY-box containing gene 110.211
Sox2SRY-box containing gene 20.210
CblCasitas B-lineage lymphoma0.208
Slit2slit homolog 2 (Drosophila)0.207
Col1a1collagen, type I, alpha 10.201
Plcg2phospholipase C, gamma 20.198
Snai1snail homolog 1 (Drosophila)0.198
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.196
Gab1growth factor receptor bound protein 2-associated protein 10.192
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dnm1ldynamin 1-like0.040
Pnnpinin, desmosome associated protein0.016
Rplp0ribosomal protein, large, P00.013
Rps21ribosomal protein S210.012
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.011
Smek2SMEK homolog 2, suppressor of mek1 (Dictyostelium)0.011
Sfrs18splicing factor, arginine/serine-rich 180.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism