The network for 'hydrogen ion transmembrane transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hydrogen ion transmembrane transport

The directed movement of hydrogen ion (proton) across a membrane.

NameDescriptionProbabilityFunc Analog Organism
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.157
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.102
cox8acytochrome c oxidase subunit 8a0.094
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.085
atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.067
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.056
zgc:111961zgc:1119610.039
cox6a1cytochrome c oxidase subunit VIa polypeptide 10.039
atp6v1g1ATPase, H+ transporting, V1 subunit G isoform 10.022
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.020
atp6v1dATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D0.012
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.011
dlstdihydrolipoamide S-succinyltransferase0.010
atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
levyCG17280 gene product from transcript CG17280-RA0.469
ATPsyn-gammaATP synthase-gamma chain0.153
porinCG6647 gene product from transcript CG6647-RA0.052
VhaSFDVacuolar H[+]-ATPase SFD subunit0.047
ArgkArginine kinase0.024
Vha26Vacuolar H[+]-ATPase 26kD E subunit0.024
MarfMitochondrial assembly regulatory factor0.022
slifslimfast0.021
Pink1PTEN-induced putative kinase 10.019
CG15609CG15609 gene product from transcript CG15609-RE0.019
Vha55Vacuolar H[+]-ATPase 55kD B subunit0.017
CG3683CG3683 gene product from transcript CG3683-RC0.014
CG12400CG12400 gene product from transcript CG12400-RA0.012
Vha68-2CG3762 gene product from transcript CG3762-RA0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.722
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.686
ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d0.488
COX5Bcytochrome c oxidase subunit Vb0.449
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.439
ATP5J2ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F20.428
ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)0.422
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.220
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.208
ATP5IATP synthase, H+ transporting, mitochondrial Fo complex, subunit E0.185
COX4I1cytochrome c oxidase subunit IV isoform 10.150
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.144
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.110
COX1cytochrome c oxidase subunit I0.098
COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)0.094
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.080
NDUFB5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa0.079
UQCRC2ubiquinol-cytochrome c reductase core protein II0.079
COX2cytochrome c oxidase subunit II0.075
COX7A2cytochrome c oxidase subunit VIIa polypeptide 2 (liver)0.070
COX6B1cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)0.066
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E10.058
COX6Ccytochrome c oxidase subunit VIc0.055
COX5Acytochrome c oxidase subunit Va0.048
UQCRHubiquinol-cytochrome c reductase hinge protein0.042
COX7Bcytochrome c oxidase subunit VIIb0.038
UQCRQubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa0.037
ATP6V1DATPase, H+ transporting, lysosomal 34kDa, V1 subunit D0.036
NDUFA1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa0.029
NDUFS4NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)0.025
NDUFB1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa0.024
MDH1malate dehydrogenase 1, NAD (soluble)0.023
NDUFA4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa0.022
ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C10.022
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.021
NDUFB9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa0.019
HINT1histidine triad nucleotide binding protein 10.017
NDUFB3NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa0.017
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.016
MRPS15mitochondrial ribosomal protein S150.016
ATP5LATP synthase, H+ transporting, mitochondrial Fo complex, subunit G0.015
ND2MTND20.013
SUCLG1succinate-CoA ligase, alpha subunit0.013
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.012
UQCR10ubiquinol-cytochrome c reductase, complex III subunit X0.011
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.010
COX7Ccytochrome c oxidase subunit VIIc0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.977
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.853
Umoduromodulin0.840
Hbb-b1hemoglobin, beta adult major chain0.622
Atp6v0bATPase, H+ transporting, lysosomal V0 subunit B0.609
Cyc1cytochrome c-10.592
Foxi1forkhead box I10.565
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.517
Atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.494
1810046J19RikRIKEN cDNA 1810046J19 gene0.388
Higd2aHIG1 domain family, member 2A0.379
Cox5bcytochrome c oxidase, subunit Vb0.373
Vamp2vesicle-associated membrane protein 20.349
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.329
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.298
BC031181cDNA sequence BC0311810.295
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.274
Ndufs3NADH dehydrogenase (ubiquinone) Fe-S protein 30.265
Hbb-b2hemoglobin, beta adult minor chain0.257
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.244
Exoc6exocyst complex component 60.228
Clstn1calsyntenin 10.204
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.195
Atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.178
Synj1synaptojanin 10.172
Slc4a4solute carrier family 4 (anion exchanger), member 40.154
Cox4i1cytochrome c oxidase subunit IV isoform 10.154
Slc12a1solute carrier family 12, member 10.151
Ovol1OVO homolog-like 1 (Drosophila)0.148
Aco2aconitase 2, mitochondrial0.146
Slc26a7solute carrier family 26, member 70.140
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.118
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.118
Aldoaaldolase A, fructose-bisphosphate0.118
1500032L24RikRIKEN cDNA 1500032L24 gene0.109
Atp6v1c1ATPase, H+ transporting, lysosomal V1 subunit C10.106
Tmem9bTMEM9 domain family, member B0.101
Atp6v1e1ATPase, H+ transporting, lysosomal V1 subunit E10.101
RragcRas-related GTP binding C0.097
Scnn1gsodium channel, nonvoltage-gated 1 gamma0.095
Atp6v1hATPase, H+ transporting, lysosomal V1 subunit H0.093
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.090
Spna1spectrin alpha 10.090
Ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.088
0910001L09RikRIKEN cDNA 0910001L09 gene0.088
Ndufc1NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 10.085
Slc12a6solute carrier family 12, member 60.083
Trappc2ltrafficking protein particle complex 2-like0.080
Tfrctransferrin receptor0.077
Slc18a1solute carrier family 18 (vesicular monoamine), member 10.076
Idh3gisocitrate dehydrogenase 3 (NAD+), gamma0.068
Uqcrc1ubiquinol-cytochrome c reductase core protein 10.067
Prkag1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.067
Ace2angiotensin I converting enzyme (peptidyl-dipeptidase A) 20.063
Sectm1bsecreted and transmembrane 1B0.059
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.058
NsfN-ethylmaleimide sensitive fusion protein0.056
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.055
Hba-a1hemoglobin alpha, adult chain 10.055
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.053
Asb9ankyrin repeat and SOCS box-containing 90.052
Acot13acyl-CoA thioesterase 130.048
Atp6v0a4ATPase, H+ transporting, lysosomal V0 subunit A40.048
Cox6a1cytochrome c oxidase, subunit VI a, polypeptide 10.047
Ndufv3NADH dehydrogenase (ubiquinone) flavoprotein 30.046
Ccl20chemokine (C-C motif) ligand 200.046
Pcsk4proprotein convertase subtilisin/kexin type 40.046
Slc22a13solute carrier family 22 (organic cation transporter), member 130.046
Tmprss6transmembrane serine protease 60.046
BsndBartter syndrome, infantile, with sensorineural deafness (Barttin)0.045
Wbp2WW domain binding protein 20.044
Slc12a2solute carrier family 12, member 20.043
Grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.043
Ank1ankyrin 1, erythroid0.043
Copecoatomer protein complex, subunit epsilon0.042
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.041
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.041
Il17binterleukin 17B0.040
Ndufb11NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 110.039
Vps28vacuolar protein sorting 28 (yeast)0.039
Nrbp2nuclear receptor binding protein 20.039
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.038
Ms4a10membrane-spanning 4-domains, subfamily A, member 100.038
Atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.037
Slc22a8solute carrier family 22 (organic anion transporter), member 80.037
Ostaorganic solute transporter alpha0.037
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.036
Degs2degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase0.036
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.035
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.035
Ap2m1adaptor protein complex AP-2, mu10.034
Atp6v1b2ATPase, H+ transporting, lysosomal V1 subunit B20.033
Uqcr10ubiquinol-cytochrome c reductase, complex III subunit X0.033
Slc14a2solute carrier family 14 (urea transporter), member 20.032
Tmem146transmembrane protein 1460.032
Upk3auroplakin 3A0.031
Vps26avacuolar protein sorting 26 homolog A (yeast)0.031
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.030
Fxyd4FXYD domain-containing ion transport regulator 40.030
Slc5a9solute carrier family 5 (sodium/glucose cotransporter), member 90.029
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rpl31ribosomal protein L310.027
Rps7ribosomal protein S70.026
Rps26ribosomal protein S260.024
Rpl29ribosomal protein L290.019
Rpl3ribosomal protein L30.017
Rpl28ribosomal protein L280.017
Rpl34ribosomal protein L340.016
Rpl22ribosomal protein L220.012
Rpl4ribosomal protein L40.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ATP4Atp4p0.999
ATP1Atp1p0.999
ATP14Atp14p0.989
ATP5Atp5p0.987
ATP18Atp18p0.963
ATP2Atp2p0.945
ATP7Atp7p0.914
ATP20Atp20p0.905
TIM11Tim11p0.613
ATP3Atp3p0.550
INH1Inh1p0.504
ATP17Atp17p0.470
ATP16Atp16p0.302
MIR1Mir1p0.193
COX8Cox8p0.181
ATP15Atp15p0.159
PET9Pet9p0.152
QCR2Qcr2p0.096
COX4Cox4p0.094
RPM2Rpm2p0.094
VMA4Vma4p0.075
MDH1Mdh1p0.073
ATP6Atp6p0.066
VMA13Vma13p0.057
COX7Cox7p0.044
COX13Cox13p0.039
NDE1Nde1p0.039
QCR6Qcr6p0.038
SRD1Srd1p0.034
YLR162Whypothetical protein0.030
YCR023Chypothetical protein0.027
LEU2Leu2p0.027
YOL038C-Ahypothetical protein0.026
YLR264C-Ahypothetical protein0.026
ARP10Arp10p0.026
YJR120Whypothetical protein0.026
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.026
UPS3Ups3p0.025
HXT3Hxt3p0.024
MER1Mer1p0.024
MF(ALPHA)2Mf(alpha)2p0.024
LPX1Lpx1p0.024
ATP8Atp8p0.023
OPT2Opt2p0.023
CUP1-1Cup1-1p0.022
SPL2Spl2p0.022
YCL057C-Ahypothetical protein0.021
CAM1Cam1p0.021
YLR042Chypothetical protein0.020
COX9Cox9p0.020
AGP1Agp1p0.020
AGC1Agc1p0.020
YPR157Whypothetical protein0.020
YAR068Whypothetical protein0.020
ZPS1Zps1p0.020
AUA1Aua1p0.019
MF(ALPHA)1Mf(alpha)1p0.018
YBR013Chypothetical protein0.018
KNH1Knh1p0.018
FMT1Fmt1p0.018
CPD1Cpd1p0.017
HPF1Hpf1p0.017
DUR1,2Dur1,2p0.016
SCM4Scm4p0.016
AQY2Aqy2p0.016
YDR090Chypothetical protein0.016
REE1Ree1p0.016
YKR075Chypothetical protein0.015
HOR2Hor2p0.015
YIR035Chypothetical protein0.015
BSC1Bsc1p0.015
YPR096Chypothetical protein0.015
PTR2Ptr2p0.014
RRN5Rrn5p0.014
MIG2Mig2p0.014
MFA2Mfa2p0.014
NRG2Nrg2p0.014
YLL053Chypothetical protein0.014
BI4Bi4p0.014
ARG8Arg8p0.014
MDJ2Mdj2p0.014
BNA4Bna4p0.014
TIM8Tim8p0.014
MDL2Mdl2p0.014
TIR3Tir3p0.013
YAL037C-Ahypothetical protein0.013
BI3Bi3p0.013
YLR040Chypothetical protein0.013
ICS2Ics2p0.013
TOM7Tom7p0.013
DIC1Dic1p0.013
PEX2Pex2p0.013
ARO10Aro10p0.013
PDR5Pdr5p0.013
YNL058Chypothetical protein0.013
YOL013W-Ahypothetical protein0.013
NEO1Neo1p0.013
CHA1Cha1p0.013
ENA5Ena5p0.013
CAR1Car1p0.013