The network for 'light adaption' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

light adaption

The ability of a photoreceptor to adjust to varying levels of light.

NameDescriptionProbabilityFunc Analog Organism
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.449
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.125
esr2aestrogen receptor 2a0.118
gc3guanylyl cyclase 30.091
kif5bakinesin family member 5B, a0.090
kiss1rbKISS1 receptor b0.079
opn1sw2opsin 1 (cone pigments), short-wave-sensitive 20.073
guk1guanylate kinase 10.063
msi1musashi homolog 1 (Drosophila)0.059
guca1cguanylate cyclase activator 1C0.054
LOC799612prolactin 20.054
chatcholine acetyltransferase0.050
znf711zinc finger protein 7110.045
vdravitamin D receptor a0.040
aanat2arylalkylamine N-acetyltransferase0.040
terttelomerase reverse transcriptase0.038
guca1dguanylate cyclase activator 1d0.037
LOC100003330melanocortin-2 receptor accessory protein 2-like0.036
crxcone-rod homeobox0.036
rx1retinal homeobox gene 10.035
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.031
rspo1R-spondin homolog (Xenopus laevis)0.029
igfbp6ainsulin-like growth factor binding protein 6a0.028
slc6a8solute carrier family 6 (neurotransmitter transporter, creatine), member 80.028
vasavasa homolog0.028
cacnb2bcalcium channel, voltage-dependent, beta 2b0.027
paqr8progestin and adipoQ receptor family member VIII0.026
zfyve26zinc finger, FYVE domain containing 260.026
th2tyrosine hydroxylase 20.026
itgb1b.1integrin, beta 1b.10.024
synj1synaptojanin 10.024
crhbpcorticotropin releasing hormone binding protein0.021
fasFas (TNF receptor superfamily, member 6)0.021
socs1suppressor of cytokine signaling 10.020
pcsk1proprotein convertase subtilisin/kexin type 10.019
park7parkinson disease (autosomal recessive, early onset) 70.019
inppl1ainositol polyphosphate phosphatase-like 1a0.019
kiss2kisspeptin 20.018
sagaS-antigen; retina and pineal gland (arrestin) a0.018
cyp1d1cytochrome P450, family 1, subfamily D, polypeptide 10.018
opn1lw1opsin 1 (cone pigments), long-wave-sensitive, 10.017
slc25a27solute carrier family 25, member 270.017
rpe65aretinal pigment epithelium-specific protein 65a0.016
gnat1guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 10.016
LOC569642hypothetical protein LOC5696420.015
furinbfurin (paired basic amino acid cleaving enzyme) b0.015
kif5bbkinesin family member 5B, b0.014
mtnr1bbmelatonin receptor 1B b and melatonin receptor 1B0.014
rbp4lretinol binding protein 4, like0.014
cadm1bcell adhesion molecule 1b0.014
lmnalamin A0.013
LOC100332193growth hormone secretagogue receptor type 1-like0.013
ndrg1N-myc downstream regulated gene 10.013
defbl3defensin, beta-like 30.013
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.012
ddcdopa decarboxylase0.012
prom1bprominin 1 b0.012
fads2fatty acid desaturase 20.012
opn1sw1opsin 1 (cone pigments), short-wave-sensitive 10.012
lhcgrluteinizing hormone/choriogonadotropin receptor0.012
per2period homolog 2 (Drosophila)0.011
ift52intraflagellar transport protein 520.011
cadm2bcell adhesion molecule 2b0.011
ppm1aaprotein phosphatase, Mg2+/Mn2+ dependent, 1Aa0.011
rdh5retinol dehydrogenase 5 (11-cis/9-cis)0.011
foxg1bforkhead box G1b0.011
grk7aG-protein-coupled receptor kinase 7a0.010
pcsk7proprotein convertase subtilisin/kexin type 70.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
trptransient receptor potential0.331
inaCinactivation no afterpotential C0.203
norpAno receptor potential A0.160
ninaEneither inactivation nor afterpotential E0.084
inaDinactivation no afterpotential D0.068
18w18 wheeler0.065
elavembryonic lethal abnormal vision0.055
Rh3Rhodopsin 30.041
Arr2Arrestin 20.038
CG9821CG9821 gene product from transcript CG9821-RB0.030
Xe7CG2179 gene product from transcript CG2179-RA0.029
ShabShaker cognate b0.027
Gbeta76CG protein beta-subunit 76C0.024
ninaCneither inactivation nor afterpotential C0.023
cpocouch potato0.023
Tsp42EjTetraspanin 42Ej0.022
Ilp2Insulin-like peptide 20.021
hipkhomeodomain interacting protein kinase0.020
KaiRIACG18039 gene product from transcript CG18039-RA0.018
Rh5Rhodopsin 50.017
l(1)G0289lethal (1) G02890.016
Kr-h1Kruppel homolog 10.016
RdlResistant to dieldrin0.015
Rh6Rhodopsin 60.015
CG1561CG1561 gene product from transcript CG1561-RB0.015
CG13792CG13792 gene product from transcript CG13792-RA0.014
CG17826CG17826 gene product from transcript CG17826-RA0.014
Ca-alpha1DCa[2+]-channel protein alpha[[1]] subunit D0.014
CG32627CG32627 gene product from transcript CG32627-RA0.013
CG32532CG32532 gene product from transcript CG32532-RA0.012
CG10477CG10477 gene product from transcript CG10477-RA0.011
CG14440CG14440 gene product from transcript CG14440-RA0.011
CG9733CG9733 gene product from transcript CG9733-RA0.011
CG18327CG18327 gene product from transcript CG18327-RA0.011
GATAeCG10278 gene product from transcript CG10278-RB0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Plxnd1plexin D10.279
Ldb3LIM domain binding 30.183
Clockcircadian locomotor output cycles kaput0.139
Vegfavascular endothelial growth factor A0.109
Arntlaryl hydrocarbon receptor nuclear translocator-like0.107
Prkceprotein kinase C, epsilon0.059
BrafBraf transforming gene0.052
Slc23a2solute carrier family 23 (nucleobase transporters), member 20.050
Dmddystrophin, muscular dystrophy0.048
Pecam1platelet/endothelial cell adhesion molecule 10.038
Hif1ahypoxia inducible factor 1, alpha subunit0.038
Ednraendothelin receptor type A0.033
Camk2dcalcium/calmodulin-dependent protein kinase II, delta0.031
Ptk2PTK2 protein tyrosine kinase 20.030
Egln3EGL nine homolog 3 (C. elegans)0.030
Pde6bphosphodiesterase 6B, cGMP, rod receptor, beta polypeptide0.028
Id1inhibitor of DNA binding 10.027
Nfibnuclear factor I/B0.027
Ncoa1nuclear receptor coactivator 10.025
Nf1neurofibromatosis 10.025
Flt1FMS-like tyrosine kinase 10.024
Mkl2MKL/myocardin-like 20.023
Chrna6cholinergic receptor, nicotinic, alpha polypeptide 60.023
Rdh10retinol dehydrogenase 10 (all-trans)0.021
FynFyn proto-oncogene0.020
Apbb2amyloid beta (A4) precursor protein-binding, family B, member 20.020
Ptpn11protein tyrosine phosphatase, non-receptor type 110.020
Il6stinterleukin 6 signal transducer0.020
Cry1cryptochrome 1 (photolyase-like)0.019
Vav3vav 3 oncogene0.019
Per2period homolog 2 (Drosophila)0.019
Cux1cut-like homeobox 10.018
Rbp3retinol binding protein 3, interstitial0.018
Tcf4transcription factor 40.017
Ece1endothelin converting enzyme 10.017
Neurod4neurogenic differentiation 40.017
Lamb1laminin B10.016
Slc17a1solute carrier family 17 (sodium phosphate), member 10.016
Acvr1activin A receptor, type 10.016
Hexahexosaminidase A0.016
Hivep2human immunodeficiency virus type I enhancer binding protein 20.016
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.015
Crhcorticotropin releasing hormone0.015
Itm2cintegral membrane protein 2C0.014
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.014
Cry2cryptochrome 2 (photolyase-like)0.013
Crxos1Crx opposite strand transcript 10.013
Hipk3homeodomain interacting protein kinase 30.013
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.013
Dlg2discs, large homolog 2 (Drosophila)0.013
2310002J15RikRIKEN cDNA 2310002J15 gene0.013
Neurod1neurogenic differentiation 10.013
Fstl1follistatin-like 10.013
Efnb2ephrin B20.012
Kdrkinase insert domain protein receptor0.012
Cd83CD83 antigen0.012
Prkcaprotein kinase C, alpha0.012
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.011
Igf1insulin-like growth factor 10.011
Aipl1aryl hydrocarbon receptor-interacting protein-like 10.011
Plxna2plexin A20.011
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.011
Nos1nitric oxide synthase 1, neuronal0.011
Vsx1visual system homeobox 1 homolog (zebrafish)0.011
Adam17a disintegrin and metallopeptidase domain 170.011
Ebf3early B-cell factor 30.011
Ptenphosphatase and tensin homolog0.010
Ebf1early B-cell factor 10.010
Ptprbprotein tyrosine phosphatase, receptor type, B0.010
Kitlkit ligand0.010
Rit2Ras-like without CAAX 20.010
Hspa4lheat shock protein 4 like0.010
Pkd2polycystic kidney disease 20.010
Nr1d2nuclear receptor subfamily 1, group D, member 20.010
Mtmr1myotubularin related protein 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism