The network for 'eye photoreceptor cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

eye photoreceptor cell development

Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.

NameDescriptionProbabilityFunc Analog Organism
ift88intraflagellar transport 88 homolog0.996
pax2apaired box gene 2a0.991
tfap2atranscription factor AP-2 alpha0.989
pax6bpaired box gene 6b0.980
shhasonic hedgehog a0.969
kif17kinesin family member 170.906
otx2orthodenticle homolog 20.894
six3bsine oculis homeobox homolog 3b0.855
tbx2bT-box 2b0.837
bmp4bone morphogenetic protein 40.833
tbx2aT-box gene 2a0.801
fgf8afibroblast growth factor 8 a0.778
myf5myogenic factor 50.774
cdh2cadherin 2, neuronal0.622
flhfloating head0.582
nr2e3nuclear receptor subfamily 2, group E, member 30.538
crxcone-rod homeobox0.528
ptf1apancreas specific transcription factor, 1a0.464
otx5orthodenticle homolog 50.428
bmperBMP binding endothelial regulator0.408
sox2SRY-box containing gene 20.407
aldh1a2aldehyde dehydrogenase 1 family, member A20.399
foxa2forkhead box A20.390
rxraaretinoid X receptor, alpha a0.390
rx2retinal homeobox gene 20.380
neurog1neurogenin 10.359
rx3retinal homeobox gene 30.349
eya1eyes absent homolog 10.340
crb2acrumbs homolog 2a0.337
otx1borthodenticle homolog 1b0.318
pcdh17protocadherin 170.310
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.298
epb41l5erythrocyte membrane protein band 4.1 like 50.268
myod1myogenic differentiation 10.260
jag2jagged 20.242
pdzd7aPDZ domain containing 7a0.240
bmp2bbone morphogenetic protein 2b0.238
znf503zinc finger protein 5030.232
irx7iroquois homeobox protein 70.229
vsx2visual system homeobox 20.226
irx4airoquois homeobox protein 4a0.225
rorcbRAR-related orphan receptor C b0.222
sox9aSRY-box containing gene 9a0.217
barhl2BarH-like 20.217
crb3acrumbs homolog 3a0.214
bhlhe22basic helix-loop-helix family, member e220.214
her1hairy-related 10.208
gbx1gastrulation brain homeobox 10.203
crb1crumbs homolog 1 (Drosophila)0.201
sox9bSRY-box containing gene 9b0.199
hnf1baHNF1 homeobox Ba0.192
irx1biroquois homeobox protein 1, b0.185
nr1d1nuclear receptor subfamily 1, group d, member 10.184
neurodneurogenic differentiation0.184
mespamesoderm posterior a0.180
ntlano tail a0.180
foxi1forkhead box I10.173
gfi1.2growth factor independent 1.20.170
clrn1clarin 10.167
dnmt8DNA (cytosine-5-)-methyltransferase 80.162
meis2.1myeloid ecotropic viral integration site 2.10.160
crb2bcrumbs homolog 2b0.151
gbx2gastrulation brain homeo box 20.148
tbx20T-box 200.147
pcdh8protocadherin 80.145
atoh7atonal homolog 70.145
ncam1bneural cell adhesion molecule 1b0.139
fezf2FEZ family zinc finger 20.139
fgf10afibroblast growth factor 10a0.138
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.124
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.124
cacnb2bcalcium channel, voltage-dependent, beta 2b0.123
dmbx1adiencephalon/mesencephalon homeobox 1a0.123
ret1receptor tyrosine kinase0.120
fstafollistatin a0.117
lhx1aLIM homeobox 1a0.113
egr1early growth response 10.112
guca1cguanylate cyclase activator 1C0.108
evx1even-skipped homeobox 10.106
pea3ETS-domain transcription factor pea30.101
jam2bjunctional adhesion molecule 2b0.097
crb3bcrumbs homolog 3b0.097
cc2d2acoiled-coil and C2 domain containing 2A0.096
rpgrretinitis pigmentosa GTPase regulator protein 10.096
dbx1adeveloping brain homeobox 1a0.095
cry3cryptochrome 30.095
irx1airoquois homeobox protein 1, a0.093
slc25a37solute carrier family 25, member 370.089
nod2nucleotide-binding oligomerization domain containing 20.087
msgn1mesogenin 10.084
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.084
fgf3fibroblast growth factor 30.083
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.083
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Fas2Fasciclin 20.998
trioCG18214 gene product from transcript CG18214-RA0.944
Akt1CG4006 gene product from transcript CG4006-RA0.883
S6kIIRPS6-protein kinase-II0.867
spensplit ends0.831
Rme-8Receptor mediated endocytosis 80.741
ninaEneither inactivation nor afterpotential E0.699
hydhyperplastic discs0.645
X11LCG5675 gene product from transcript CG5675-RB0.621
CG31120CG31120 gene product from transcript CG31120-RB0.604
cdicenter divider0.549
argosCG4531 gene product from transcript CG4531-RA0.527
vvlventral veins lacking0.519
ari-2ariadne 20.510
mbtmushroom bodies tiny0.495
RalaRas-related protein0.480
Mi-2CG8103 gene product from transcript CG8103-RA0.469
aPKCatypical protein kinase C0.459
Arr1Arrestin 10.432
HopHsp70/Hsp90 organizing protein homolog0.421
slikSterile20-like kinase0.396
MrtfMyocardin-related transcription factor0.386
trptransient receptor potential0.378
amosabsent MD neurons and olfactory sensilla0.377
Dhc64CDynein heavy chain 64C0.365
PtenCG5671 gene product from transcript CG5671-RB0.362
sosine oculis0.358
Prosalpha1Proteasome alpha1 subunit0.353
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.350
BicDBicaudal D0.348
Kap-alpha3karyopherin alpha30.347
jingCG9397 gene product from transcript CG9397-RI0.339
Taf6TBP-associated factor 60.333
InRInsulin-like receptor0.327
Arr2Arrestin 20.322
eyseyes shut0.313
unc-5CG8166 gene product from transcript CG8166-RA0.305
dltdiscs lost0.302
piepineapple eye0.293
jebjelly belly0.287
Tsc1CG6147 gene product from transcript CG6147-RA0.284
elavembryonic lethal abnormal vision0.283
svpseven up0.282
WASpCG1520 gene product from transcript CG1520-RA0.281
sinaseven in absentia0.280
Atx-1Ataxin 10.273
sec5CG8843 gene product from transcript CG8843-RA0.272
dallydivision abnormally delayed0.272
NmnatNicotinamide mononucleotide adenylyltransferase0.266
Hr51Hormone receptor 510.251
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.249
Src64BSrc oncogene at 64B0.238
Rh5Rhodopsin 50.237
VangVan Gogh0.235
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pax6paired box gene 61.000
Otx2orthodenticle homolog 2 (Drosophila)0.999
Crb2crumbs homolog 2 (Drosophila)0.999
Atoh7atonal homolog 7 (Drosophila)0.999
Prph2peripherin 20.997
Nr2e1nuclear receptor subfamily 2, group E, member 10.994
Dlx5distal-less homeobox 50.994
Pax2paired box gene 20.993
Emx1empty spiracles homolog 1 (Drosophila)0.993
Crxcone-rod homeobox containing gene0.991
Foxc1forkhead box C10.989
Isl1ISL1 transcription factor, LIM/homeodomain0.987
Tcfap2atranscription factor AP-2, alpha0.985
Gli3GLI-Kruppel family member GLI30.982
Pax3paired box gene 30.973
Pitx2paired-like homeodomain transcription factor 20.966
Shhsonic hedgehog0.956
Fgfr2fibroblast growth factor receptor 20.936
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.928
Sox2SRY-box containing gene 20.928
Fgf8fibroblast growth factor 80.921
Hoxa1homeobox A10.868
Thrathyroid hormone receptor alpha0.836
Tbx5T-box 50.832
Gbx2gastrulation brain homeobox 20.832
Foxc2forkhead box C20.806
Eya1eyes absent 1 homolog (Drosophila)0.778
Bmp4bone morphogenetic protein 40.772
Msx2homeobox, msh-like 20.771
Ift88intraflagellar transport 88 homolog (Chlamydomonas)0.764
Neurod1neurogenic differentiation 10.759
Tulp1tubby like protein 10.713
Hand2heart and neural crest derivatives expressed transcript 20.710
Fgfr1fibroblast growth factor receptor 10.704
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.688
Pcm1pericentriolar material 10.683
Ptpn11protein tyrosine phosphatase, non-receptor type 110.657
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.633
Chd7chromodomain helicase DNA binding protein 70.624
Ntf3neurotrophin 30.618
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.581
Gucy2dguanylate cyclase 2d0.578
Neurog2neurogenin 20.559
Bbs2Bardet-Biedl syndrome 2 (human)0.556
Gucy2eguanylate cyclase 2e0.541
Raxretina and anterior neural fold homeobox0.533
Otx1orthodenticle homolog 1 (Drosophila)0.531
Akt1thymoma viral proto-oncogene 10.527
Runx2runt related transcription factor 20.509
Pde6gphosphodiesterase 6G, cGMP-specific, rod, gamma0.496
Scn5asodium channel, voltage-gated, type V, alpha0.465
Zeb1zinc finger E-box binding homeobox 10.460
Foxg1forkhead box G10.458
Cav1caveolin 1, caveolae protein0.451
Pou4f2POU domain, class 4, transcription factor 20.439
Aipl1aryl hydrocarbon receptor-interacting protein-like 10.432
Rargretinoic acid receptor, gamma0.426
Ptenphosphatase and tensin homolog0.414
Tbx3T-box 30.410
Grb10growth factor receptor bound protein 100.406
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.400
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.397
Ptf1apancreas specific transcription factor, 1a0.379
Tbx1T-box 10.378
Gja5gap junction protein, alpha 50.374
Ift57intraflagellar transport 57 homolog (Chlamydomonas)0.373
Nrlneural retina leucine zipper gene0.371
Pcp2Purkinje cell protein 2 (L7)0.361
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.353
Neurod4neurogenic differentiation 40.348
Cngb3cyclic nucleotide gated channel beta 30.346
Atxn1ataxin 10.337
Bdnfbrain derived neurotrophic factor0.331
Cabp5calcium binding protein 50.326
Gata3GATA binding protein 30.322
Hand1heart and neural crest derivatives expressed transcript 10.320
Prrx1paired related homeobox 10.315
Rbp3retinol binding protein 3, interstitial0.314
Pcdh15protocadherin 150.314
Twist2twist homolog 2 (Drosophila)0.308
Gsx2GS homeobox 20.301
Notch2Notch gene homolog 2 (Drosophila)0.297
Emx2empty spiracles homolog 2 (Drosophila)0.296
Sox4SRY-box containing gene 40.286
Ednraendothelin receptor type A0.285
Rit2Ras-like without CAAX 20.280
Myo6myosin VI0.274
Flt4FMS-like tyrosine kinase 40.264
Tgfb1transforming growth factor, beta 10.264
Iqcb1IQ calmodulin-binding motif containing 10.259
Dclk1doublecortin-like kinase 10.257
Trpm1transient receptor potential cation channel, subfamily M, member 10.255
Myo7amyosin VIIA0.252
Cplx4complexin 40.251
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rtn1reticulon 10.024
Rbp3retinol binding protein 3, interstitial0.017
Dnm1dynamin 10.015
Necab1N-terminal EF-hand calcium binding protein 10.013
Nrxn3neurexin 30.013
Chgbchromogranin B0.013
Nr4a3nuclear receptor subfamily 4, group A, member 30.012
Slc5a7solute carrier family 5 (choline transporter), member 70.011
Calb1calbindin 10.011
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.010
Cdc2l5cell division cycle 2-like 5 (cholinesterase-related cell division controller)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism