The network for 'hemopoiesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

NameDescriptionProbabilityFunc Analog Organism
cmybtranscription factor cmyb1.000
tal1T-cell acute lymphocytic leukemia 10.999
gata1aGATA binding protein 1a0.999
kdrlkinase insert domain receptor like0.994
runx1runt-related transcription factor 10.994
tfr1atransferrin receptor 1a0.993
notch3notch homolog 30.992
alas2aminolevulinate, delta-, synthetase 20.991
bmp2bbone morphogenetic protein 2b0.990
LOC566708FL cytokine receptor-like0.978
hbbe1.1hemoglobin beta embryonic-1.10.968
plcg1phospholipase C, gamma 10.962
ikzf1IKAROS family zinc finger 1 (Ikaros)0.956
gata6GATA-binding protein 60.950
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.948
cdx4caudal type homeo box transcription factor 40.940
hbbe3hemoglobin beta embryonic-30.936
tbx1T-box 10.936
uroduroporphyrinogen decarboxylase0.920
hoxd4ahomeo box D4a0.896
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.895
smad5MAD homolog 5 (Drosophila)0.882
ccnd1cyclin D10.879
hhexhematopoietically expressed homeobox0.873
tgfb3transforming growth factor, beta 30.871
hbae1hemoglobin alpha embryonic-10.855
gdf6agrowth differentiation factor 6a0.850
LOC100151531zinc finger protein Gfi-1b-like0.847
gata5GATA-binding protein 50.844
rag1recombination activating gene 10.840
osr1odd-skipped related 1 (Drosophila)0.840
etv2ets variant gene 20.833
f2rcoagulation factor II (thrombin) receptor0.831
hhiphedgehog interacting protein0.822
pax2apaired box gene 2a0.816
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.811
pdcd2programmed cell death 20.798
pitx2paired-like homeodomain transcription factor 20.795
tll1tolloid-like 10.782
trpv6transient receptor potential cation channel, subfamily V, member 60.779
hand2heart and neural crest derivatives expressed transcript 20.777
hbaa1hemoglobin alpha adult-10.772
npm1nucleophosmin 10.766
rpl36aribosomal protein L36A0.765
notch1anotch homolog 1a0.759
slc4a1asolute carrier family 4, anion exchanger, member 1a0.758
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.757
fgf10afibroblast growth factor 10a0.757
ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.751
slc25a37solute carrier family 25, member 370.734
gata2aGATA-binding protein 2a0.725
hbae3hemoglobin alpha embryonic-30.707
gsnagelsolin a0.701
wnt2bbwingless-type MMTV integration site family, member 2Bb0.684
cfl2lcofilin 2, like0.681
rhagRhesus blood group-associated glycoprotein0.678
wnt7bawingless-type MMTV integration site family, member 7Ba0.670
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.665
tp53tumor protein p530.664
metmet proto-oncogene (hepatocyte growth factor receptor)0.663
hnf1baHNF1 homeobox Ba0.662
rpl22l1ribosomal protein L22-like 10.657
il7rinterleukin 7 receptor0.656
acvr1lactivin A receptor, type I like0.656
hdrhematopoietic death receptor0.652
mef2camyocyte enhancer factor 2ca0.648
ndr2nodal-related 20.648
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.643
tpm4tropomyosin 40.636
aplnrbapelin receptor b0.631
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.625
fras1Fraser syndrome 10.625
cpoxcoproporphyrinogen oxidase0.622
tbx6T-box gene 60.609
nrarpanotch-regulated ankyrin repeat protein a0.604
tbx24T-box 240.602
rpl11ribosomal protein L110.600
fgf3fibroblast growth factor 30.583
klf4Kruppel-like factor 40.562
cdh5cadherin 50.561
fgf8afibroblast growth factor 8 a0.560
tmem88atransmembrane protein 88 a0.557
pkp1plakophilin 10.555
ldb2aLIM-domain binding factor 2a0.551
igf1rbinsulin-like growth factor 1b receptor0.547
spry4sprouty (Drosophila) homolog 40.544
sox2SRY-box containing gene 20.540
spint1aserine peptidase inhibitor, Kunitz type 1 a0.538
fn1fibronectin 10.537
sulf1sulfatase 10.527
znfl2azinc finger-like gene 2a0.523
tie1endothelium-specific receptor tyrosine kinase 10.516
trim33tripartite motif-containing 330.514
haus3HAUS augmin-like complex, subunit 30.510
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.507
foxi1forkhead box I10.505
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.905
cicubitus interruptus0.876
Sin3ACG8815 gene product from transcript CG8815-RC0.768
drkdownstream of receptor kinase0.737
rapretina aberrant in pattern0.710
PvrPDGF- and VEGF-receptor related0.583
Atg1Autophagy-specific gene 10.461
Pi3K92ECG4141 gene product from transcript CG4141-RB0.431
Src64BSrc oncogene at 64B0.390
cupCG11181 gene product from transcript CG11181-RB0.372
CtBPC-terminal Binding Protein0.371
SmoxSmad on X0.325
aopanterior open0.321
RalaRas-related protein0.311
cortoCG2530 gene product from transcript CG2530-RA0.298
E(spl)Enhancer of split0.296
DadDaughters against dpp0.290
Dsor1Downstream of raf10.272
fs(1)Nfemale sterile (1) Nasrat0.245
argosCG4531 gene product from transcript CG4531-RA0.242
HcfHost cell factor0.185
InRInsulin-like receptor0.182
Ptp69DProtein tyrosine phosphatase 69D0.174
osaCG7467 gene product from transcript CG7467-RD0.158
zfh1Zn finger homeodomain 10.151
Rac2CG8556 gene product from transcript CG8556-RA0.149
ImpIGF-II mRNA-binding protein0.147
RpL7ARibosomal protein L7A0.136
dosdaughter of sevenless0.136
p120ctnAdherens junction protein p1200.134
G-oalpha47AG protein oalpha 47A0.130
HsfHeat shock factor0.127
tefutelomere fusion0.127
Rab11Rab-protein 110.126
Mnn1Menin 10.124
S6kIIRPS6-protein kinase-II0.122
HLHmdeltaE(spl) region transcript mdelta0.122
Dcp-1Death caspase-10.119
MrtfMyocardin-related transcription factor0.119
HLHm3E(spl) region transcript m30.117
EgfrEpidermal growth factor receptor0.117
HLHmgammaE(spl) region transcript mgamma0.115
mbcmyoblast city0.115
fasfaint sausage0.110
hipkhomeodomain interacting protein kinase0.100
unc-13CG2999 gene product from transcript CG2999-RA0.097
MadMothers against dpp0.096
CG5794CG5794 gene product from transcript CG5794-RB0.095
slp1sloppy paired 10.094
CG10414CG10414 gene product from transcript CG10414-RA0.092
debcldeath executioner Bcl-2 homologue0.089
Traf4TNF-receptor-associated factor 40.089
RASSF8CG5053 gene product from transcript CG5053-RA0.088
sxcsuper sex combs0.088
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GRB2growth factor receptor-bound protein 21.000
TRAF1TNF receptor-associated factor 10.998
JUNjun proto-oncogene0.993
SMAD2SMAD family member 20.992
LCKlymphocyte-specific protein tyrosine kinase0.987
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.987
NCOR2nuclear receptor corepressor 20.987
RUNX1runt-related transcription factor 10.983
BIRC3baculoviral IAP repeat containing 30.981
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.979
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.974
SYKspleen tyrosine kinase0.972
IL4Rinterleukin 4 receptor0.961
PTPN6protein tyrosine phosphatase, non-receptor type 60.957
PTPN11protein tyrosine phosphatase, non-receptor type 110.950
TP53tumor protein p530.947
ICAM1intercellular adhesion molecule 10.940
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.932
CCL4chemokine (C-C motif) ligand 40.923
JUNBjun B proto-oncogene0.918
CCR5chemokine (C-C motif) receptor 50.918
MDM2Mdm2 p53 binding protein homolog (mouse)0.918
SHC1SHC (Src homology 2 domain containing) transforming protein 10.912
TAL1T-cell acute lymphocytic leukemia 10.911
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.903
IL2RBinterleukin 2 receptor, beta0.892
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.885
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.885
TRAF2TNF receptor-associated factor 20.882
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.882
VEGFAvascular endothelial growth factor A0.879
CFLARCASP8 and FADD-like apoptosis regulator0.877
HIST1H2BDhistone cluster 1, H2bd0.874
CCL5chemokine (C-C motif) ligand 50.873
TNFAIP3tumor necrosis factor, alpha-induced protein 30.869
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.866
NCOR1nuclear receptor corepressor 10.866
CASP3caspase 3, apoptosis-related cysteine peptidase0.861
CD86CD86 molecule0.859
HDAC3histone deacetylase 30.858
NOTCH1notch 10.856
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.853
CD40CD40 molecule, TNF receptor superfamily member 50.846
KLF4Kruppel-like factor 4 (gut)0.841
BRCA1breast cancer 1, early onset0.838
EGFRepidermal growth factor receptor0.834
IRF1interferon regulatory factor 10.834
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.832
FGFR1fibroblast growth factor receptor 10.823
TNFtumor necrosis factor0.816
CCR7chemokine (C-C motif) receptor 70.814
ESR1estrogen receptor 10.806
SIN3ASIN3 homolog A, transcription regulator (yeast)0.799
IL8interleukin 80.795
CAV1caveolin 1, caveolae protein, 22kDa0.793
HIST1H3Dhistone cluster 1, H3d0.793
HLA-Cmajor histocompatibility complex, class I, C0.787
ANXA1annexin A10.786
SMAD3SMAD family member 30.785
SLAMF1signaling lymphocytic activation molecule family member 10.778
HDAC1histone deacetylase 10.765
PBX1pre-B-cell leukemia homeobox 10.762
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.758
GATA1GATA binding protein 1 (globin transcription factor 1)0.753
JAG1jagged 10.753
PRPF38APRP38 pre-mRNA processing factor 38 (yeast) domain containing A0.750
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.748
FOSFBJ murine osteosarcoma viral oncogene homolog0.747
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.739
LATlinker for activation of T cells0.737
HIST1H2AEhistone cluster 1, H2ae0.737
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.732
IL10RAinterleukin 10 receptor, alpha0.731
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.726
FASLGFas ligand (TNF superfamily, member 6)0.721
XIAPX-linked inhibitor of apoptosis0.718
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.714
VAV1vav 1 guanine nucleotide exchange factor0.712
SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi10.712
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.710
HIST1H2BGhistone cluster 1, H2bg0.708
SH2D1ASH2 domain containing 1A0.706
TCF12transcription factor 120.692
HIST1H1Chistone cluster 1, H1c0.691
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.684
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.683
HLA-Gmajor histocompatibility complex, class I, G0.683
ZNF43zinc finger protein 430.681
CXCL10chemokine (C-X-C motif) ligand 100.666
HIPK2homeodomain interacting protein kinase 20.658
GATA2GATA binding protein 20.658
DAXXdeath-domain associated protein0.652
CD80CD80 molecule0.641
TGFB1transforming growth factor, beta 10.639
HLA-Bmajor histocompatibility complex, class I, B0.633
PPARAperoxisome proliferator-activated receptor alpha0.632
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.628
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.612
RIPK2receptor-interacting serine-threonine kinase 20.608
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dusp1dual specificity phosphatase 10.419
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.192
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.188
Ccl5chemokine (C-C motif) ligand 50.182
Cd4Cd4 molecule0.173
Slco2b1solute carrier organic anion transporter family, member 2b10.169
Jak1Janus kinase 10.166
Cd37CD37 molecule0.139
Cd2Cd2 molecule0.108
Csf1rcolony stimulating factor 1 receptor0.092
RT1-BaRT1 class II, locus Ba0.090
Rgs1regulator of G-protein signaling 10.090
Dusp6dual specificity phosphatase 60.078
Ccl4chemokine (C-C motif) ligand 40.076
Cd247Cd247 molecule0.073
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.070
Hckhemopoietic cell kinase0.070
LOC287167globin, alpha0.070
Prrx1paired related homeobox 10.069
Barhl2BarH-like homeobox 20.068
Cfpcomplement factor properdin0.067
Acacbacetyl-Coenzyme A carboxylase beta0.067
Zfp36zinc finger protein 360.066
Il2rbinterleukin 2 receptor, beta0.061
Igh-6immunoglobulin heavy chain 60.061
Lyz2lysozyme 20.061
Smad1SMAD family member 10.059
Bmp6bone morphogenetic protein 60.057
Mylk2myosin light chain kinase 20.057
Tgfbr3transforming growth factor, beta receptor III0.057
Nfyanuclear transcription factor-Y alpha0.056
Gzmkgranzyme K0.055
Tgfbr2transforming growth factor, beta receptor II0.055
Alox5arachidonate 5-lipoxygenase0.053
Ptpn18protein tyrosine phosphatase, non-receptor type 180.052
Olr837olfactory receptor 8370.050
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.050
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.049
Gdnfglial cell derived neurotrophic factor0.049
Cd86CD86 molecule0.048
RT1-DaRT1 class II, locus Da0.047
RT1-Db1RT1 class II, locus Db10.046
FosFBJ osteosarcoma oncogene0.044
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.044
Btg2BTG family, member 20.044
Laptm5lysosomal protein transmembrane 50.044
Sec14l3SEC14-like 3 (S. cerevisiae)0.043
Inpp5dinositol polyphosphate-5-phosphatase D0.042
Hbb-b1hemoglobin, beta adult major chain0.042
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.042
TcrbT-cell receptor beta chain0.042
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.041
Gja5gap junction protein, alpha 50.041
Jak2Janus kinase 20.041
Cd5Cd5 molecule0.039
Prf1perforin 1 (pore forming protein)0.039
Apol3apolipoprotein L, 30.039
FaslgFas ligand (TNF superfamily, member 6)0.038
Lcp2lymphocyte cytosolic protein 20.037
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.037
LOC100134871beta globin minor gene0.036
Stat4signal transducer and activator of transcription 40.035
Junbjun B proto-oncogene0.035
Myo1fmyosin IF0.034
Smad7SMAD family member 70.033
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.033
Ccr5chemokine (C-C motif) receptor 50.033
Man2b1mannosidase, alpha, class 2B, member 10.033
Grb2growth factor receptor bound protein 20.033
Zfp36l2zinc finger protein 36, C3H type-like 20.033
Ly6blymphocyte antigen 6 complex, locus B0.033
Flt4fms-related tyrosine kinase 40.032
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.032
LOC687711similar to small nuclear ribonucleoprotein D30.032
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.032
Egfrepidermal growth factor receptor0.032
C1qacomplement component 1, q subcomponent, A chain0.031
Dcaf7DDB1 and CUL4 associated factor 70.031
Slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.030
Errfi1ERBB receptor feedback inhibitor 10.030
Abi3ABI family, member 30.030
Cd180CD180 molecule0.030
Klf6Kruppel-like factor 60.030
Cxcr3chemokine (C-X-C motif) receptor 30.029
Nkg7natural killer cell group 7 sequence0.029
Grm5glutamate receptor, metabotropic 50.029
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.029
Mcpt3mast cell peptidase 30.029
Cfdcomplement factor D (adipsin)0.028
Akap1A kinase (PRKA) anchor protein 10.028
Pipprolactin induced protein0.028
Map4k1mitogen activated protein kinase kinase kinase kinase 10.028
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.028
Prkchprotein kinase C, eta0.027
Prlhprolactin releasing hormone0.027
Serpini2serine (or cysteine) peptidase inhibitor, clade I, member 20.027
Sirpasignal-regulatory protein alpha0.027
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism