The network for 'leukocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leukocyte migration

The movement of a leukocyte within or between different tissues and organs of the body.

NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.824
itgb1b.2integrin, beta 1b.20.355
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.327
mmp9matrix metalloproteinase 90.303
kirrel3lkin of IRRE like 3 like0.146
mpxmyeloid-specific peroxidase0.089
nod1nucleotide-binding oligomerization domain containing 10.086
ppargperoxisome proliferator activated receptor gamma0.084
tie1endothelium-specific receptor tyrosine kinase 10.079
stc1lstanniocalcin 1, like0.074
gcm2glial cells missing homolog 2 (Drosophila)0.073
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.073
ptger2aprostaglandin E receptor 2a (subtype EP2)0.072
fli1afriend leukemia integration 1a0.072
mmp13amatrix metalloproteinase 13a0.056
itgb1aintegrin, beta 1a0.056
csf3rcolony stimulating factor 3 receptor (granulocyte)0.054
metap2methionyl aminopeptidase 20.052
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.052
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.052
ptprcprotein tyrosine phosphatase, receptor type, C0.051
vegfcvascular endothelial growth factor c0.051
wt1bwilms tumor 1b0.049
col12a1collagen, type XII, alpha 10.044
ncf1neutrophil cytosolic factor 10.042
ptpn6protein tyrosine phosphatase, non-receptor type 60.042
csf1racolony stimulating factor 1 receptor, a0.041
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.041
lcp1lymphocyte cytosolic plastin 10.036
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.031
itgb1bintegrin, beta 1b0.031
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.031
itgb1b.1integrin, beta 1b.10.031
LOC557072caspase recruitment domain-containing protein 11-like0.031
hoxb2ahomeo box B2a0.031
cdh5cadherin 50.030
rargaretinoic acid receptor gamma a0.029
esamaendothelial cell adhesion molecule a0.029
yrkYes-related kinase0.029
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.029
pak2ap21 (CDKN1A)-activated kinase 2a0.028
btkBruton agammaglobulinemia tyrosine kinase0.028
fli1bfriend leukemia integration 1b0.027
prkciprotein kinase C, iota0.027
cyt1type I cytokeratin, enveloping layer0.026
col6a3collagen, type VI, alpha 30.026
LOC100000934hypothetical protein LOC1000009340.026
pvrl1apoliovirus receptor-related 1a0.025
ikzf1IKAROS family zinc finger 1 (Ikaros)0.024
ntlano tail a0.024
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.024
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.024
ntd5ntl-dependent gene 50.023
fetubfetuin B0.022
col17a1acollagen, type XVII, alpha 1a0.022
slco2b1solute carrier organic anion transporter family, member 2B10.021
itga2bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)0.020
sult1st4sulfotransferase family 1, cytosolic sulfotransferase 40.020
sox4aSRY-box containing gene 4a0.020
st3gal5lST3 beta-galactoside alpha-2,3-sialyltransferase 5, like0.019
tlx2T-cell leukemia, homeobox 20.019
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.019
fevFEV (ETS oncogene family)0.019
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.018
rc3rabconnectin 30.018
dzip1DAZ interacting protein 10.018
lta4hleukotriene A4 hydrolase0.018
postnperiostin, osteoblast specific factor0.018
scinlascinderin like a0.018
hfe2hemochromatosis type 20.018
cldneclaudin e0.018
kirrelbkin of IRRE like b0.018
pcsk5aproprotein convertase subtilisin/kexin type 5a0.017
cdc42cell division cycle 420.017
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.017
coro1acoronin, actin binding protein, 1A0.017
caspbcaspase b and caspase b-like0.017
plekhg5apleckstrin homology domain containing, family G (with RhoGef domain) member 5a0.017
rhogbras homolog gene family, member Gb0.017
ptgs2aprostaglandin-endoperoxide synthase 2a0.016
nos2bnitric oxide synthase 2b, inducible0.016
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.016
hspb1heat shock protein, alpha-crystallin-related, 10.016
thy1Thy-1 cell surface antigen0.016
prrx1apaired related homeobox 1a0.016
f2rcoagulation factor II (thrombin) receptor0.016
vtg7vitellogenin 70.016
pou1f1POU domain, class 1, transcription factor 10.016
tmprss4atransmembrane protease, serine 4a0.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.998
FHL2four and a half LIM domains 20.996
CCR5chemokine (C-C motif) receptor 50.995
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.989
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.980
FN1fibronectin 10.979
IL8interleukin 80.973
SYKspleen tyrosine kinase0.971
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.962
S100A6S100 calcium binding protein A60.960
MDM2Mdm2 p53 binding protein homolog (mouse)0.959
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.958
LCKlymphocyte-specific protein tyrosine kinase0.954
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.951
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.932
S100A11S100 calcium binding protein A110.931
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.930
CCL5chemokine (C-C motif) ligand 50.930
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.920
S100A9S100 calcium binding protein A90.915
LAPTM5lysosomal protein transmembrane 50.909
VEGFAvascular endothelial growth factor A0.908
CXCL9chemokine (C-X-C motif) ligand 90.891
GRB2growth factor receptor-bound protein 20.883
PDIA3protein disulfide isomerase family A, member 30.882
HOXB5homeobox B50.878
VCAM1vascular cell adhesion molecule 10.872
TAL1T-cell acute lymphocytic leukemia 10.854
CD44CD44 molecule (Indian blood group)0.845
CXCL2chemokine (C-X-C motif) ligand 20.838
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.837
S100A4S100 calcium binding protein A40.831
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.827
RHOAras homolog gene family, member A0.823
CXCL3chemokine (C-X-C motif) ligand 30.807
PTPN6protein tyrosine phosphatase, non-receptor type 60.802
S100A1S100 calcium binding protein A10.787
CCR7chemokine (C-C motif) receptor 70.773
S100BS100 calcium binding protein B0.770
CCL22chemokine (C-C motif) ligand 220.764
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.764
CXCL10chemokine (C-X-C motif) ligand 100.745
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.717
IL2RBinterleukin 2 receptor, beta0.713
IL1Binterleukin 1, beta0.709
CASP8caspase 8, apoptosis-related cysteine peptidase0.707
SELPLGselectin P ligand0.704
CXCL5chemokine (C-X-C motif) ligand 50.698
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.694
CCL20chemokine (C-C motif) ligand 200.688
CCL7chemokine (C-C motif) ligand 70.676
VAV1vav 1 guanine nucleotide exchange factor0.672
CAV1caveolin 1, caveolae protein, 22kDa0.670
ICAM1intercellular adhesion molecule 10.664
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.650
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.648
CCL19chemokine (C-C motif) ligand 190.631
ANXA2annexin A20.628
CCL2chemokine (C-C motif) ligand 20.626
IL6interleukin 6 (interferon, beta 2)0.625
S100A8S100 calcium binding protein A80.623
LAIR1leukocyte-associated immunoglobulin-like receptor 10.607
PLAURplasminogen activator, urokinase receptor0.599
DPP4dipeptidyl-peptidase 40.595
CD33CD33 molecule0.595
PTPRCprotein tyrosine phosphatase, receptor type, C0.594
AXLAXL receptor tyrosine kinase0.592
LST1leukocyte specific transcript 10.582
NRP1neuropilin 10.574
CD63CD63 molecule0.569
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.533
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.528
THBS1thrombospondin 10.517
SOS1son of sevenless homolog 1 (Drosophila)0.512
TIMP1TIMP metallopeptidase inhibitor 10.504
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.494
IFNGinterferon, gamma0.487
LATlinker for activation of T cells0.485
EGFRepidermal growth factor receptor0.484
IQGAP1IQ motif containing GTPase activating protein 10.484
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.482
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.479
CCR1chemokine (C-C motif) receptor 10.476
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.470
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.470
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.455
S100A12S100 calcium binding protein A120.449
TFF1trefoil factor 10.449
NCF2neutrophil cytosolic factor 20.447
FASLGFas ligand (TNF superfamily, member 6)0.445
TNFAIP3tumor necrosis factor, alpha-induced protein 30.445
MYD88myeloid differentiation primary response gene (88)0.443
TBXA2Rthromboxane A2 receptor0.437
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccr2chemokine (C-C motif) receptor 20.997
Mmp9matrix metallopeptidase 90.980
Selpselectin, platelet0.979
Ltblymphotoxin B0.965
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.957
Csf1colony stimulating factor 1 (macrophage)0.949
FasFas (TNF receptor superfamily member 6)0.929
Ptgs2prostaglandin-endoperoxide synthase 20.914
Cd44CD44 antigen0.914
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.913
Ccl2chemokine (C-C motif) ligand 20.907
Nos2nitric oxide synthase 2, inducible0.903
Il1binterleukin 1 beta0.899
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.889
Efnb2ephrin B20.885
Ccl4chemokine (C-C motif) ligand 40.879
Tnftumor necrosis factor0.876
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.870
Ccr1chemokine (C-C motif) receptor 10.847
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.818
Kitlkit ligand0.806
Itgb2integrin beta 20.805
S100a8S100 calcium binding protein A8 (calgranulin A)0.797
Ifnginterferon gamma0.781
Itgaxintegrin alpha X0.780
MefvMediterranean fever0.776
Cx3cr1chemokine (C-X3-C) receptor 10.761
Itgalintegrin alpha L0.735
Map3k14mitogen-activated protein kinase kinase kinase 140.723
Ptgirprostaglandin I receptor (IP)0.721
Tgfb1transforming growth factor, beta 10.720
Inpp5dinositol polyphosphate-5-phosphatase D0.708
Cxcl2chemokine (C-X-C motif) ligand 20.705
Snai1snail homolog 1 (Drosophila)0.695
Ednrbendothelin receptor type B0.687
Il1rninterleukin 1 receptor antagonist0.686
Nos3nitric oxide synthase 3, endothelial cell0.682
Cxcl13chemokine (C-X-C motif) ligand 130.672
Pcdh12protocadherin 120.661
Slfn1schlafen 10.630
Icam1intercellular adhesion molecule 10.615
Ccl3chemokine (C-C motif) ligand 30.614
C5ar1complement component 5a receptor 10.610
Plauplasminogen activator, urokinase0.605
Has1hyaluronan synthase10.604
Gpr132G protein-coupled receptor 1320.575
Itgb1integrin beta 1 (fibronectin receptor beta)0.555
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.554
Osmroncostatin M receptor0.552
Hoxa1homeobox A10.550
Ptprcprotein tyrosine phosphatase, receptor type, C0.538
Ngpneutrophilic granule protein0.537
Rac2RAS-related C3 botulinum substrate 20.533
Fcgr1Fc receptor, IgG, high affinity I0.531
Irg1immunoresponsive gene 10.530
SrcRous sarcoma oncogene0.526
Gdnfglial cell line derived neurotrophic factor0.524
Acvrl1activin A receptor, type II-like 10.523
Ncf4neutrophil cytosolic factor 40.517
Nf1neurofibromatosis 10.510
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.497
Fxyd5FXYD domain-containing ion transport regulator 50.497
Vav1vav 1 oncogene0.491
Vav3vav 3 oncogene0.491
Mmp3matrix metallopeptidase 30.490
Itgb3integrin beta 30.489
Tbx3T-box 30.483
Il2rginterleukin 2 receptor, gamma chain0.481
Il10rainterleukin 10 receptor, alpha0.479
Bdkrb1bradykinin receptor, beta 10.471
Sh2d2aSH2 domain protein 2A0.466
Lyz2lysozyme 20.452
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.451
Pdcd1programmed cell death 10.446
Tmod3tropomodulin 30.444
Flt4FMS-like tyrosine kinase 40.437
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.437
Ch25hcholesterol 25-hydroxylase0.435
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.432
Plaurplasminogen activator, urokinase receptor0.430
Cd40CD40 antigen0.429
Trem3triggering receptor expressed on myeloid cells 30.429
Ltbp2latent transforming growth factor beta binding protein 20.428
Apoeapolipoprotein E0.426
Cxcr3chemokine (C-X-C motif) receptor 30.425
Il7rinterleukin 7 receptor0.420
Myo7amyosin VIIA0.419
AF251705cDNA sequence AF2517050.413
Kitkit oncogene0.412
Sellselectin, lymphocyte0.411
Ccl12chemokine (C-C motif) ligand 120.408
Leprleptin receptor0.408
Rock2Rho-associated coiled-coil containing protein kinase 20.404
Ccl7chemokine (C-C motif) ligand 70.402
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.399
Myo1fmyosin IF0.398
Il1r1interleukin 1 receptor, type I0.397
Rab3il1RAB3A interacting protein (rabin3)-like 10.397
Selplgselectin, platelet (p-selectin) ligand0.389
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ccl4chemokine (C-C motif) ligand 40.931
Ptafrplatelet-activating factor receptor0.884
Il1binterleukin 1 beta0.789
Il6interleukin 60.732
Cxcl10chemokine (C-X-C motif) ligand 100.640
Mmp10matrix metallopeptidase 100.579
Il8rbinterleukin 8 receptor, beta0.576
Mmp3matrix metallopeptidase 30.553
Ccl2chemokine (C-C motif) ligand 20.551
Ccl3chemokine (C-C motif) ligand 30.533
RT1-DaRT1 class II, locus Da0.463
Neurl3neuralized homolog 3 (Drosophila)0.408
Il1ainterleukin 1 alpha0.392
Col12a1collagen, type XII, alpha 10.384
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.379
Cd53Cd53 molecule0.350
F2rl1coagulation factor II (thrombin) receptor-like 10.350
Plauplasminogen activator, urokinase0.322
Adam2ADAM metallopeptidase domain 20.316
Cxcl2chemokine (C-X-C motif) ligand 20.293
Cd14CD14 molecule0.285
Prkcgprotein kinase C, gamma0.272
Il1rninterleukin 1 receptor antagonist0.265
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.235
Olr1500olfactory receptor 15000.233
Sellselectin L0.226
Il9rinterleukin 9 receptor0.224
Reg3gregenerating islet-derived 3 gamma0.219
Pfn1profilin 10.208
Trim47tripartite motif-containing 470.200
Gzmkgranzyme K0.198
Seleselectin E0.195
Ednraendothelin receptor type A0.195
Tnftumor necrosis factor (TNF superfamily, member 2)0.187
Madcam1mucosal vascular addressin cell adhesion molecule 10.186
Hckhemopoietic cell kinase0.185
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.181
Laptm5lysosomal protein transmembrane 50.178
Fosl1fos-like antigen 10.175
Adora2aadenosine A2a receptor0.172
Csf1colony stimulating factor 1 (macrophage)0.163
Reg3bregenerating islet-derived 3 beta0.157
TcrbT-cell receptor beta chain0.154
Ccr5chemokine (C-C motif) receptor 50.154
Rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.152
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.141
Cst7cystatin F (leukocystatin)0.140
Pspparotid secretory protein0.139
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.133
Metmet proto-oncogene0.131
Mmp12matrix metallopeptidase 120.131
Fgf2fibroblast growth factor 20.130
Ptprcprotein tyrosine phosphatase, receptor type, C0.127
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.127
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.126
Slc28a3solute carrier family 28 (sodium-coupled nucleoside transporter), member 30.124
Akr1c18aldo-keto reductase family 1, member C180.120
Mmp8matrix metallopeptidase 80.115
Gzmbgranzyme B0.114
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.113
Clic4chloride intracellular channel 40.111
Crisp1cysteine-rich secretory protein 10.111
Slc30a2solute carrier family 30 (zinc transporter), member 20.110
RGD1564327similar to integrin alpha 80.109
Coro1acoronin, actin binding protein 1A0.107
Cd4Cd4 molecule0.105
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.105
Olr1654olfactory receptor 16540.100
Sdcbp2syndecan binding protein (syntenin) 20.097
Socs3suppressor of cytokine signaling 30.096
P2ry14purinergic receptor P2Y, G-protein coupled, 140.095
Icam1intercellular adhesion molecule 10.094
Ncf4neutrophil cytosolic factor 40.093
Il1r2interleukin 1 receptor, type II0.093
Efnb1ephrin B10.092
Ptger4prostaglandin E receptor 4 (subtype EP4)0.092
Itpr2inositol 1,4,5-triphosphate receptor, type 20.091
Ptpreprotein tyrosine phosphatase, receptor type, E0.090
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.086
Aqp8aquaporin 80.086
Cd37CD37 molecule0.085
Olfml2bolfactomedin-like 2B0.084
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.083
Leprleptin receptor0.079
Itga6integrin, alpha 60.078
Ccr2chemokine (C-C motif) receptor 20.078
Ccdc102acoiled-coil domain containing 102A0.077
Il2rginterleukin 2 receptor, gamma0.076
RT1-BaRT1 class II, locus Ba0.076
Lst1leukocyte specific transcript 10.074
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.072
Slit3slit homolog 3 (Drosophila)0.070
Il1rl1interleukin 1 receptor-like 10.070
Cd44Cd44 molecule0.070
Tfpi2tissue factor pathway inhibitor 20.069
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.068
Cd2Cd2 molecule0.068
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism