The network for 'lens morphogenesis in camera type eye' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lens morphogenesis in camera type eye

The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.

NameDescriptionProbabilityFunc Analog Organism
crygmxl2crystallin, gamma MX, like 20.891
sox2SRY-box containing gene 20.850
dlcdeltaC0.833
zgc:153846zgc:1538460.717
foxa2forkhead box A20.619
pax6apaired box gene 6a0.551
crygm6crystallin, gamma M60.533
crygm3crystallin, gamma M30.504
pea3ETS-domain transcription factor pea30.372
ascl1aachaete-scute complex-like 1a (Drosophila)0.372
mab21l2mab-21-like 20.342
crygm1crystallin, gamma M10.337
trpm7transient receptor potential cation channel, subfamily M, member 70.321
otx2orthodenticle homolog 20.297
sox10SRY-box containing gene 100.263
pax6bpaired box gene 6b0.262
otx1borthodenticle homolog 1b0.207
crygmxl1crystallin, gamma MX, like 10.204
foxa3forkhead box A30.190
cryba4crystallin, beta A40.186
nr2e1nuclear receptor subfamily 2, group E, member 10.184
crygm2fcrystallin, gamma M2f0.183
cdh2cadherin 2, neuronal0.177
crygmxcrystallin, gamma MX0.168
zgc:103750zgc:1037500.168
crybb1crystallin, beta B10.165
crygm2acrystallin, gamma M2a0.153
bmperBMP binding endothelial regulator0.152
crygm2d16crystallin, gamma M2d160.143
crygn2crystallin, gamma N20.139
foxi3bforkhead box I3b0.137
crygn1crystallin, gamma N10.117
crygm2d11crystallin, gamma M2d110.111
zgc:171792zgc:1717920.111
tp63tumor protein p630.104
crygs4crystallin, gamma S40.103
crygm2d8crystallin, gamma M2d80.101
zdhhc8bzinc finger, DHHC-type containing 8b0.100
foxi1forkhead box I10.094
crygm2d15crystallin, gamma M2d150.093
crygm2bcrystallin, gamma M2b0.091
pxnpaxillin0.090
six3bsine oculis homeobox homolog 3b0.082
rx3retinal homeobox gene 30.078
rx2retinal homeobox gene 20.076
crygm7crystallin, gamma M70.073
tfap2ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.071
crygm2d13crystallin, gamma M2d130.068
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.068
nrarpanotch-regulated ankyrin repeat protein a0.068
zic1zic family member 1 (odd-paired homolog, Drosophila)0.066
crygm2d6crystallin, gamma M2d60.064
her1hairy-related 10.063
rargaretinoic acid receptor gamma a0.062
dnmt4DNA (cytosine-5-)-methyltransferase 40.059
pitx2paired-like homeodomain transcription factor 20.059
six2asine oculis-related homeobox 2a0.057
cdoncell adhesion molecule-related/down-regulated by oncogenes0.055
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.055
pax2apaired box gene 2a0.054
myod1myogenic differentiation 10.050
crygs1crystallin, gamma S10.050
rbp4retinol binding protein 4, plasma0.049
tfe3btranscription factor binding to IGHM enhancer 3b0.048
rx1retinal homeobox gene 10.047
efnb2aephrin B2a0.046
crygm2d12crystallin, gamma M2d120.045
her6hairy-related 60.044
bmp2bbone morphogenetic protein 2b0.044
vcanaversican a0.043
vsx2visual system homeobox 20.043
fgfrl1bfibroblast growth factor receptor-like 1b0.041
hmx4H6 family homeobox 40.038
coe2coe20.036
vwfvon Willebrand factor0.034
cryba2acrystallin, beta A2a0.034
gbx2gastrulation brain homeo box 20.034
bocbrother of CDO0.034
crygm4crystallin, gamma M40.033
emx2empty spiracles homeobox 20.033
pdgfaaplatelet-derived growth factor alpha a0.032
crygm5crystallin, gamma M50.031
crygm2d2crystallin, gamma M2d20.031
sfrp1bsecreted frizzled-related protein 1b0.031
foxe3forkhead box E30.030
six3asine oculis homeobox homolog 3a0.029
foxa1forkhead box A10.029
foxg1aforkhead box G1a0.029
fgf3fibroblast growth factor 30.029
tnctenascin C0.029
rad21RAD21 homolog (S. pombe)0.028
foxi3aforkhead box I3a0.028
bhlhe22basic helix-loop-helix family, member e220.028
emx3empty spiracles homeobox 30.028
pknox2pbx/knotted 1 homeobox 20.027
crygm2d10crystallin, gamma M2d100.027
fgfr2fibroblast growth factor receptor 20.027
sox1aSRY-box containing gene 1a0.026
dmrt2adoublesex and mab-3 related transcription factor 2a0.025
crygm2ccrystallin, gamma M2c0.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.988
SP1Sp1 transcription factor0.985
SMAD4SMAD family member 40.974
SMAD3SMAD family member 30.934
CREBBPCREB binding protein0.889
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.888
EP300E1A binding protein p3000.877
ENGendoglin0.835
PBX1pre-B-cell leukemia homeobox 10.800
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.742
PVRL4poliovirus receptor-related 40.567
SKILSKI-like oncogene0.551
HNF4Ahepatocyte nuclear factor 4, alpha0.524
PXNpaxillin0.514
CTGFconnective tissue growth factor0.507
RASSF5Ras association (RalGDS/AF-6) domain family member 50.467
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.451
DCAF7DDB1 and CUL4 associated factor 70.420
RUNX1runt-related transcription factor 10.396
HCFC1host cell factor C1 (VP16-accessory protein)0.381
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.357
EFNA1ephrin-A10.333
SMAD2SMAD family member 20.333
SMAD1SMAD family member 10.249
SIN3ASIN3 homolog A, transcription regulator (yeast)0.231
TACC1transforming, acidic coiled-coil containing protein 10.194
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.160
ZFYVE9zinc finger, FYVE domain containing 90.159
BTRCbeta-transducin repeat containing0.159
FBLN1fibulin 10.150
FGF1fibroblast growth factor 1 (acidic)0.147
POU5F1POU class 5 homeobox 10.140
PVRL2poliovirus receptor-related 2 (herpesvirus entry mediator B)0.122
MEIS2Meis homeobox 20.122
WWP2WW domain containing E3 ubiquitin protein ligase 20.118
SREBF2sterol regulatory element binding transcription factor 20.116
SH3BP4SH3-domain binding protein 40.108
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.107
TCF4transcription factor 40.107
HTThuntingtin0.100
KCTD1potassium channel tetramerisation domain containing 10.098
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.096
PVRL3poliovirus receptor-related 30.093
APCadenomatous polyposis coli0.088
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.088
MECP2methyl CpG binding protein 2 (Rett syndrome)0.085
VCLvinculin0.081
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.079
PDLIM5PDZ and LIM domain 50.077
NFIXnuclear factor I/X (CCAAT-binding transcription factor)0.074
HIPK2homeodomain interacting protein kinase 20.074
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.073
FHL2four and a half LIM domains 20.066
BCAR1breast cancer anti-estrogen resistance 10.066
TRIM33tripartite motif containing 330.064
PMLpromyelocytic leukemia0.063
TGFB1I1transforming growth factor beta 1 induced transcript 10.062
ZYXzyxin0.061
SALL2sal-like 2 (Drosophila)0.060
ACTN1actinin, alpha 10.059
FGFR2fibroblast growth factor receptor 20.059
NR5A2nuclear receptor subfamily 5, group A, member 20.052
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.050
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.050
IGFBP3insulin-like growth factor binding protein 30.048
EPAS1endothelial PAS domain protein 10.048
FOXD3forkhead box D30.043
FLNAfilamin A, alpha0.041
IPO13importin 130.040
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.038
FERMT2fermitin family member 20.038
PTPN1protein tyrosine phosphatase, non-receptor type 10.037
TGFB1transforming growth factor, beta 10.036
BCRbreakpoint cluster region0.034
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.034
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.034
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.034
TP53tumor protein p530.033
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.032
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.032
CSNK1Dcasein kinase 1, delta0.031
CYR61cysteine-rich, angiogenic inducer, 610.028
PTPN23protein tyrosine phosphatase, non-receptor type 230.028
GLIS2GLIS family zinc finger 20.028
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.027
LHX2LIM homeobox 20.027
EPHB3EPH receptor B30.027
YY1YY1 transcription factor0.027
PAX6paired box 60.026
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.026
HSPG2heparan sulfate proteoglycan 20.026
PTK2PTK2 protein tyrosine kinase 20.026
IFIT1interferon-induced protein with tetratricopeptide repeats 10.025
SOX2SRY (sex determining region Y)-box 20.025
FBXW11F-box and WD repeat domain containing 110.025
TJP1tight junction protein 1 (zona occludens 1)0.024
THBS1thrombospondin 10.023
EPHB2EPH receptor B20.023
MYH10myosin, heavy chain 10, non-muscle0.023
PTPN12protein tyrosine phosphatase, non-receptor type 120.023
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 21.000
Gli3GLI-Kruppel family member GLI31.000
Pax6paired box gene 61.000
Tcfap2atranscription factor AP-2, alpha0.999
Pax3paired box gene 30.999
Otx2orthodenticle homolog 2 (Drosophila)0.997
Sox2SRY-box containing gene 20.996
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.995
Pitx2paired-like homeodomain transcription factor 20.993
Ephb2Eph receptor B20.992
Pbx1pre B-cell leukemia transcription factor 10.991
Isl1ISL1 transcription factor, LIM/homeodomain0.991
Alx4aristaless-like homeobox 40.988
Gata4GATA binding protein 40.987
Bmp4bone morphogenetic protein 40.986
Sox9SRY-box containing gene 90.986
Nodalnodal0.985
Fgf8fibroblast growth factor 80.981
Hand1heart and neural crest derivatives expressed transcript 10.967
Hand2heart and neural crest derivatives expressed transcript 20.962
Hoxa13homeobox A130.943
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.930
Klf3Kruppel-like factor 3 (basic)0.926
Sox11SRY-box containing gene 110.914
Eya1eyes absent 1 homolog (Drosophila)0.913
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.912
Foxh1forkhead box H10.892
Msx2homeobox, msh-like 20.882
Foxc1forkhead box C10.863
Col2a1collagen, type II, alpha 10.853
Efnb2ephrin B20.831
Hoxd13homeobox D130.824
Tcfap2ctranscription factor AP-2, gamma0.819
Msx1homeobox, msh-like 10.805
Zic3zinc finger protein of the cerebellum 30.802
Tbx3T-box 30.773
Pax2paired box gene 20.771
Bmp7bone morphogenetic protein 70.740
Pou3f3POU domain, class 3, transcription factor 30.732
Meox2mesenchyme homeobox 20.694
Tgfb2transforming growth factor, beta 20.671
Hmx1H6 homeobox 10.652
Gata6GATA binding protein 60.652
Neurog2neurogenin 20.643
Efna2ephrin A20.612
Ptpn11protein tyrosine phosphatase, non-receptor type 110.608
Neurod1neurogenic differentiation 10.599
Gli2GLI-Kruppel family member GLI20.596
Ascl1achaete-scute complex homolog 1 (Drosophila)0.595
Foxf1aforkhead box F1a0.584
Alx3aristaless-like homeobox 30.567
Nkx2-1NK2 homeobox 10.565
Jag1jagged 10.558
Retret proto-oncogene0.554
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.543
Meis2Meis homeobox 20.536
Dlx1distal-less homeobox 10.509
Sema5bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.492
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.484
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.482
Tbx2T-box 20.470
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.468
Smosmoothened homolog (Drosophila)0.442
Foxg1forkhead box G10.416
Prrx1paired related homeobox 10.414
Epha4Eph receptor A40.406
Lmx1bLIM homeobox transcription factor 1 beta0.402
Atoh7atonal homolog 7 (Drosophila)0.362
Ntf3neurotrophin 30.357
Ptk7PTK7 protein tyrosine kinase 70.355
Hoxb13homeobox B130.350
Hoxa2homeobox A20.348
Barx1BarH-like homeobox 10.348
Raxretina and anterior neural fold homeobox0.347
Hes1hairy and enhancer of split 1 (Drosophila)0.339
Fgf10fibroblast growth factor 100.326
Dccdeleted in colorectal carcinoma0.311
Pax8paired box gene 80.301
Ephb3Eph receptor B30.301
Emx2empty spiracles homolog 2 (Drosophila)0.297
Hspg2perlecan (heparan sulfate proteoglycan 2)0.292
Sall3sal-like 3 (Drosophila)0.292
Rargretinoic acid receptor, gamma0.280
Dlx5distal-less homeobox 50.280
Crygdcrystallin, gamma D0.273
Trp53transformation related protein 530.266
Efsembryonal Fyn-associated substrate0.265
Alx1ALX homeobox 10.264
Gbx2gastrulation brain homeobox 20.249
Lef1lymphoid enhancer binding factor 10.247
Pitx1paired-like homeodomain transcription factor 10.243
Dkk1dickkopf homolog 1 (Xenopus laevis)0.243
Hey2hairy/enhancer-of-split related with YRPW motif 20.242
Efnb1ephrin B10.231
Acvr1activin A receptor, type 10.224
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.218
Ror2receptor tyrosine kinase-like orphan receptor 20.216
Epha2Eph receptor A20.215
Tead3TEA domain family member 30.215
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism