The network for 'regulation of cellular response to growth factor stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cellular response to growth factor stimulus

Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.

NameDescriptionProbabilityFunc Analog Organism
ephb4beph receptor B4b0.515
plcg1phospholipase C, gamma 10.481
tcf7transcription factor 7 (T-cell specific, HMG-box)0.472
dusp6dual specificity phosphatase 60.461
flhfloating head0.411
hdac4histone deacetylase 40.403
wnt10awingless-type MMTV integration site family, member 10a0.381
tbx1T-box 10.375
lef1lymphocyte enhancer binding factor 10.339
spry4sprouty (Drosophila) homolog 40.330
wnt7aawingless-type MMTV integration site family, member 7Aa0.329
wnt3wingless-type MMTV integration site family, member 30.322
wnt1wingless-type MMTV integration site family, member 10.319
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.304
hoxd4ahomeo box D4a0.296
skianuclear oncoprotein skia0.291
lama5laminin, alpha 50.285
aplnrbapelin receptor b0.277
robo1roundabout homolog 10.257
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.255
eng1aengrailed 1a0.243
bmp2bbone morphogenetic protein 2b0.239
fgf17fibroblast growth factor 170.230
wnt5bwingless-type MMTV integration site family, member 5b0.224
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.224
fbn2bfibrillin 2b0.216
rbfox2RNA binding protein, fox-1 homolog (C. elegans) 20.213
msxdmuscle segment homeobox D0.208
cdoncell adhesion molecule-related/down-regulated by oncogenes0.201
spns2spinster homolog 2 (Drosophila)0.201
ntlano tail a0.191
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.179
sept7bseptin 7b0.175
fgf3fibroblast growth factor 30.167
bmp2abone morphogenetic protein 2a0.165
dlx5adistal-less homeobox gene 5a0.159
bonbonnie and clyde0.156
tcf12transcription factor 120.155
ccm2cerebral cavernous malformation 20.150
col10a1collagen, type X, alpha 10.150
dkk1bdickkopf 1b0.149
brd4bromodomain containing 40.145
psen1presenilin 10.142
gpc4glypican 40.140
notch3notch homolog 30.138
fn1fibronectin 10.130
flot2aflotillin 2a0.126
plxnd1plexin D10.125
sox32SRY-box containing gene 320.124
nrp2bneuropilin 2b0.123
wnt4awingless-type MMTV integration site family, member 4a0.119
btg1B-cell translocation gene 10.119
lhx2bLIM homeobox 2b0.117
appaamyloid beta (A4) precursor protein a0.116
ptch1patched 10.114
hey1hairy/enhancer-of-split related with YRPW motif 10.112
bmp4bone morphogenetic protein 40.112
cdh2cadherin 2, neuronal0.112
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.112
nrp1aneuropilin 1a0.110
vegfaavascular endothelial growth factor Aa0.108
oepone-eyed pinhead0.108
tp53bp2tumor protein p53 binding protein, 20.108
lhx1aLIM homeobox 1a0.104
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.103
igf1rbinsulin-like growth factor 1b receptor0.103
efnb2aephrin B2a0.103
dachadachshund a0.101
vhlvon Hippel-Lindau tumor suppressor0.100
wnt9awingless-type MMTV integration site family, member 9A0.100
fgfr3fibroblast growth factor receptor 30.098
ndr2nodal-related 20.097
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.097
lrrc6leucine rich repeat containing 60.097
foxa2forkhead box A20.097
nf1bneurofibromin 1b0.097
wnt2bbwingless-type MMTV integration site family, member 2Bb0.096
etv5aets variant 5a0.095
fgf24fibroblast growth factor 240.094
ctnnb1catenin (cadherin-associated protein), beta 10.093
mtmr8myotubularin related protein 80.092
csnk1dacasein kinase 1, delta a0.090
rspo3R-spondin 3 homolog (Xenopus laevis)0.089
unc45aunc-45 homolog A (C. elegans)0.087
ism1isthmin 10.086
her12hairy-related 120.086
ephb4aeph receptor B4a0.086
hoxd13ahomeo box D13a0.083
hoxa13bhomeo box A13b0.082
sox17SRY-box containing gene 170.082
ptch2patched 20.081
robo3roundabout homolog 30.081
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
daf-11Protein DAF-110.400
sma-6Protein SMA-60.091
ceh-20Protein CEH-200.070
cat-1Protein CAT-10.068
pry-1Protein PRY-10.041
bar-1Protein BAR-10.035
let-60Protein LET-600.034
egl-18Protein EGL-180.029
egl-15Protein EGL-150.026
daf-3Protein DAF-30.022
unc-9Protein UNC-90.018
unc-7Protein UNC-70.017
gcy-22Protein GCY-220.016
osm-3Protein OSM-30.016
osm-6Protein OSM-60.016
lin-29Protein LIN-290.016
tag-123Protein TAG-1230.015
daf-1Protein DAF-10.015
daf-12Protein DAF-120.015
dpy-6Protein DPY-60.014
che-13Protein CHE-130.014
EGAP2.1Protein EGAP2.10.014
che-2Protein CHE-20.014
osm-5Protein OSM-50.012
tax-2Protein TAX-20.012
odr-3Protein ODR-30.012
hlh-30Protein HLH-300.012
che-1Protein CHE-10.011
lin-1Protein LIN-10.011
unc-14Protein UNC-140.011
F55A4.2Protein F55A4.20.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
EgfrEpidermal growth factor receptor0.883
MadMothers against dpp0.878
MrtfMyocardin-related transcription factor0.614
CG11347CG11347 gene product from transcript CG11347-RE0.434
cicubitus interruptus0.396
sogshort gastrulation0.323
mbcmyoblast city0.263
argosCG4531 gene product from transcript CG4531-RA0.233
DadDaughters against dpp0.198
witwishful thinking0.181
par-6CG5884 gene product from transcript CG5884-RA0.175
nocno ocelli0.132
stumpsCG31317 gene product from transcript CG31317-RC0.105
SnooSno oncogene0.104
Pi3K92ECG4141 gene product from transcript CG4141-RB0.103
Irk2Inwardly rectifying potassium channel 20.099
fkhfork head0.098
SaraSmad anchor for receptor activation0.077
CtBPC-terminal Binding Protein0.070
Hs6stHeparan sulfate 6-O-sulfotransferase0.070
mewmultiple edematous wings0.068
nompAno mechanoreceptor potential A0.065
AdarAdenosine deaminase acting on RNA0.063
CG13349CG13349 gene product from transcript CG13349-RA0.057
eyaeyes absent0.057
par-1CG8201 gene product from transcript CG8201-RA0.050
rictorrapamycin-insensitive companion of Tor0.050
Stat92ESignal-transducer and activator of transcription protein at 92E0.050
CG31122CG31122 gene product from transcript CG31122-RA0.049
fwdfour wheel drive0.048
gbbglass bottom boat0.047
Socs36ESuppressor of cytokine signaling at 36E0.046
Taf4TBP-associated factor 40.044
Cdc42CG12530 gene product from transcript CG12530-RA0.040
Akt1CG4006 gene product from transcript CG4006-RA0.040
CG10743CG10743 gene product from transcript CG10743-RB0.036
fbl6CG13213 gene product from transcript CG13213-RB0.035
elBelbow B0.035
Fak56DFocal Adhesion Kinase0.035
bowlbrother of odd with entrails limited0.035
neuroliginCG13772 gene product from transcript CG13772-RA0.034
RhoGAP100FCG1976 gene product from transcript CG1976-RB0.034
sosine oculis0.033
reporeversed polarity0.032
dlg1discs large 10.031
CG4030CG4030 gene product from transcript CG4030-RA0.030
Bx42CG8264 gene product from transcript CG8264-RA0.028
Kr-h1Kruppel homolog 10.028
tamoCG4057 gene product from transcript CG4057-RA0.028
sip1septin interacting protein 10.027
Rab5Rab-protein 50.027
C1GalTACore 1 Galactosyltransferase A0.027
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMURF2SMAD specific E3 ubiquitin protein ligase 21.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.999
SMAD4SMAD family member 40.998
SMAD3SMAD family member 30.998
FHL2four and a half LIM domains 20.985
SMAD7SMAD family member 70.985
SMAD2SMAD family member 20.981
SMAD1SMAD family member 10.976
FN1fibronectin 10.968
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.959
SKILSKI-like oncogene0.928
SMAD5SMAD family member 50.914
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.851
NRP1neuropilin 10.839
MMP14matrix metallopeptidase 14 (membrane-inserted)0.835
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.832
WWP2WW domain containing E3 ubiquitin protein ligase 20.823
SMURF1SMAD specific E3 ubiquitin protein ligase 10.818
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.810
SNX6sorting nexin 60.773
TIMP3TIMP metallopeptidase inhibitor 30.731
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.721
COL1A1collagen, type I, alpha 10.713
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.638
VEGFAvascular endothelial growth factor A0.598
PTK2PTK2 protein tyrosine kinase 20.588
PTPN23protein tyrosine phosphatase, non-receptor type 230.574
CREBBPCREB binding protein0.554
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.523
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.506
STAMBPSTAM binding protein0.472
SQSTM1sequestosome 10.462
RNF11ring finger protein 110.447
TGFBR1transforming growth factor, beta receptor 10.441
TBX5T-box 50.418
TGFB3transforming growth factor, beta 30.414
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.391
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.386
SPRY2sprouty homolog 2 (Drosophila)0.385
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.373
FLNAfilamin A, alpha0.373
COL6A1collagen, type VI, alpha 10.372
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.366
MAGEF1melanoma antigen family F, 10.345
FBLN1fibulin 10.336
FBXL12F-box and leucine-rich repeat protein 120.330
PTPRCprotein tyrosine phosphatase, receptor type, C0.325
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.322
TLN1talin 10.319
YAP1Yes-associated protein 10.311
TPBGtrophoblast glycoprotein0.310
SMN1survival of motor neuron 1, telomeric0.309
CTGFconnective tissue growth factor0.292
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.276
PIAS4protein inhibitor of activated STAT, 40.263
BCAR1breast cancer anti-estrogen resistance 10.263
POU3F2POU class 3 homeobox 20.260
DLG1discs, large homolog 1 (Drosophila)0.258
EP300E1A binding protein p3000.243
DTNAdystrobrevin, alpha0.243
EPAS1endothelial PAS domain protein 10.239
SDC2syndecan 20.237
CXXC5CXXC finger protein 50.235
TMSB4Xthymosin beta 4, X-linked0.233
EGFRepidermal growth factor receptor0.231
SPRED1sprouty-related, EVH1 domain containing 10.230
PAX3paired box 30.230
DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 110.222
NCK2NCK adaptor protein 20.222
ARandrogen receptor0.217
SNX1sorting nexin 10.217
PGFplacental growth factor0.210
ZFYVE9zinc finger, FYVE domain containing 90.210
HIC1hypermethylated in cancer 10.207
IER3immediate early response 30.202
TCF4transcription factor 40.202
PDIA3protein disulfide isomerase family A, member 30.199
LOXlysyl oxidase0.197
TIMP2TIMP metallopeptidase inhibitor 20.197
ABI2abl-interactor 20.194
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.191
COL4A1collagen, type IV, alpha 10.187
PDCD6IPprogrammed cell death 6 interacting protein0.185
FGFR1fibroblast growth factor receptor 10.177
SNRNP70small nuclear ribonucleoprotein 70kDa (U1)0.173
TSC22D1TSC22 domain family, member 10.172
PTPN12protein tyrosine phosphatase, non-receptor type 120.167
SIRT1sirtuin 10.166
FGF1fibroblast growth factor 1 (acidic)0.162
CTBP1C-terminal binding protein 10.162
COL1A2collagen, type I, alpha 20.159
SNX33sorting nexin 330.159
TESK1testis-specific kinase 10.157
STAM2signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.149
SHC1SHC (Src homology 2 domain containing) transforming protein 10.149
TGFB1transforming growth factor, beta 10.148
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.985
Fgf10fibroblast growth factor 100.954
Leprleptin receptor0.941
Smad6MAD homolog 6 (Drosophila)0.917
Gata6GATA binding protein 60.915
Fgfr2fibroblast growth factor receptor 20.911
Shhsonic hedgehog0.890
Tgfbr2transforming growth factor, beta receptor II0.845
Vegfavascular endothelial growth factor A0.815
Apcadenomatosis polyposis coli0.815
Smad3MAD homolog 3 (Drosophila)0.813
Tgfb2transforming growth factor, beta 20.799
Fbn1fibrillin 10.798
Cdkn1bcyclin-dependent kinase inhibitor 1B0.795
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.752
Lef1lymphoid enhancer binding factor 10.746
Thbs1thrombospondin 10.739
Nos3nitric oxide synthase 3, endothelial cell0.715
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.711
Twist2twist homolog 2 (Drosophila)0.696
Ptk7PTK7 protein tyrosine kinase 70.693
Acvr1activin A receptor, type 10.686
Smad4MAD homolog 4 (Drosophila)0.681
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.676
Nr3c1nuclear receptor subfamily 3, group C, member 10.672
Trp53transformation related protein 530.616
Col1a1collagen, type I, alpha 10.605
Nf1neurofibromatosis 10.585
Foxf1aforkhead box F1a0.576
Jag1jagged 10.553
Tbx3T-box 30.545
Smad7MAD homolog 7 (Drosophila)0.542
Rdh10retinol dehydrogenase 10 (all-trans)0.533
Bmpr1abone morphogenetic protein receptor, type 1A0.531
Fgfr1fibroblast growth factor receptor 10.527
Fzd4frizzled homolog 4 (Drosophila)0.524
Notch2Notch gene homolog 2 (Drosophila)0.515
Rarbretinoic acid receptor, beta0.513
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.507
Bmp4bone morphogenetic protein 40.487
Plxna1plexin A10.471
Arandrogen receptor0.469
Trp63transformation related protein 630.465
Kdrkinase insert domain protein receptor0.463
Efnb2ephrin B20.461
Flt4FMS-like tyrosine kinase 40.455
Wlswntless homolog (Drosophila)0.454
Fzd8frizzled homolog 8 (Drosophila)0.448
Hes1hairy and enhancer of split 1 (Drosophila)0.444
Twist1twist homolog 1 (Drosophila)0.438
Sox4SRY-box containing gene 40.432
Lmx1aLIM homeobox transcription factor 1 alpha0.430
Onecut1one cut domain, family member 10.427
Msh2mutS homolog 2 (E. coli)0.424
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.422
Ptch2patched homolog 20.409
Dkk1dickkopf homolog 1 (Xenopus laevis)0.400
Pitx2paired-like homeodomain transcription factor 20.399
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.391
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.385
Gpc3glypican 30.384
Gdnfglial cell line derived neurotrophic factor0.382
Acvrl1activin A receptor, type II-like 10.376
Aebp1AE binding protein 10.374
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.370
Pkd1polycystic kidney disease 1 homolog0.367
Fgf8fibroblast growth factor 80.366
Pou3f1POU domain, class 3, transcription factor 10.361
BrafBraf transforming gene0.350
Plcd1phospholipase C, delta 10.349
Itgb3integrin beta 30.347
Gdf1growth differentiation factor 10.345
Fgf2fibroblast growth factor 20.343
Spry4sprouty homolog 4 (Drosophila)0.343
Lmnalamin A0.339
Smad1MAD homolog 1 (Drosophila)0.338
Hspg2perlecan (heparan sulfate proteoglycan 2)0.328
Hoxd11homeobox D110.327
Fli1Friend leukemia integration 10.327
Grb10growth factor receptor bound protein 100.323
Egfrepidermal growth factor receptor0.315
Map3k7mitogen-activated protein kinase kinase kinase 70.314
Pax3paired box gene 30.311
Lama5laminin, alpha 50.309
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.308
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.308
Gas1growth arrest specific 10.295
Wnt6wingless-related MMTV integration site 60.294
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.293
Tbx2T-box 20.290
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.290
Itgb1integrin beta 1 (fibronectin receptor beta)0.287
Wnt4wingless-related MMTV integration site 40.287
Wnt11wingless-related MMTV integration site 110.276
Nkx2-1NK2 homeobox 10.269
Smad2MAD homolog 2 (Drosophila)0.268
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Jak1Janus kinase 10.194
Lamc1laminin, gamma 10.077
Ece1endothelin converting enzyme 10.050
Flt1FMS-related tyrosine kinase 10.047
Nos3nitric oxide synthase 3, endothelial cell0.046
Ggt5gamma-glutamyltransferase 50.038
SnrkSNF related kinase0.034
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.031
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.028
Vegfavascular endothelial growth factor A0.026
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.026
Fgfr1Fibroblast growth factor receptor 10.025
Loxlysyl oxidase0.025
Snai1snail homolog 1 (Drosophila)0.024
Nfyanuclear transcription factor-Y alpha0.024
Nek9NIMA (never in mitosis gene a)- related kinase 90.023
Tgfbr2transforming growth factor, beta receptor II0.023
Smad7SMAD family member 70.023
Nckap1NCK-associated protein 10.020
Col4a1collagen, type IV, alpha 10.020
Nrxn1neurexin 10.018
Loxl1lysyl oxidase-like 10.018
Tspan18tetraspanin 180.018
Sox17SRY (sex determining region Y)-box 170.018
Epas1endothelial PAS domain protein 10.017
Pfkfb36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 30.017
Slco2a1solute carrier organic anion transporter family, member 2a10.017
Acvr1activin A receptor, type I0.017
Pecam1platelet/endothelial cell adhesion molecule 10.017
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.016
Metmet proto-oncogene0.016
Igfbp3insulin-like growth factor binding protein 30.016
Col12a1collagen, type XII, alpha 10.016
Cpsf2cleavage and polyadenylation specific factor 20.015
Gpr116G protein-coupled receptor 1160.014
Adcy4adenylate cyclase 40.014
Col3a1collagen, type III, alpha 10.014
Aoc3amine oxidase, copper containing 3 (vascular adhesion protein 1)0.014
Igfbp4insulin-like growth factor binding protein 40.014
Strnstriatin, calmodulin binding protein0.014
Socs2suppressor of cytokine signaling 20.014
Appamyloid beta (A4) precursor protein0.013
Timp3TIMP metallopeptidase inhibitor 30.013
Hsp90b1heat shock protein 90, beta, member 10.013
Clcn4-2chloride channel 4-20.013
Tgm2transglutaminase 2, C polypeptide0.013
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.013
Cishcytokine inducible SH2-containing protein0.013
Olfml2bolfactomedin-like 2B0.013
Bmp6bone morphogenetic protein 60.013
Stat6signal transducer and activator of transcription 60.013
Atp7bATPase, Cu++ transporting, beta polypeptide0.012
Ctshcathepsin H0.012
Gja1gap junction protein, alpha 10.012
Slit3slit homolog 3 (Drosophila)0.012
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.012
Il1rapinterleukin 1 receptor accessory protein0.012
Gja4gap junction protein, alpha 40.011
Mark2MAP/microtubule affinity-regulating kinase 20.011
Prkchprotein kinase C, eta0.011
Tpi1triosephosphate isomerase 10.011
Myo1dmyosin ID0.011
Arntaryl hydrocarbon receptor nuclear translocator0.011
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.011
Vldlrvery low density lipoprotein receptor0.011
Col4a2collagen, type IV, alpha 20.011
Ndfip1Nedd4 family interacting protein 10.011
Arhgap28Rho GTPase activating protein 280.011
Fermt2fermitin family homolog 2 (Drosophila)0.010
Aif1lallograft inflammatory factor 1-like0.010
Ecm1extracellular matrix protein 10.010
Atp1b3ATPase, Na+/K+ transporting, beta 3 polypeptide0.010
Fn1fibronectin 10.010
Lyve1lymphatic vessel endothelial hyaluronan receptor 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism