The network for 'cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.967
shhasonic hedgehog a0.952
gdf6agrowth differentiation factor 6a0.950
efnb2aephrin B2a0.934
foxn4forkhead box N40.910
per3period homolog 3 (Drosophila)0.890
bmp2bbone morphogenetic protein 2b0.870
aurkbaurora kinase B0.768
pax2apaired box gene 2a0.758
wnt11rwingless-type MMTV integration site family, member 11, related0.707
wnt2bbwingless-type MMTV integration site family, member 2Bb0.702
gpr126G protein-coupled receptor 1260.681
gro1groucho 10.662
sox3SRY-box containing gene 30.661
pcnaproliferating cell nuclear antigen0.598
mmp2matrix metalloproteinase 20.595
rpl19ribosomal protein L190.582
tbx5aT-box 5a0.564
pbx4pre-B-cell leukemia transcription factor 40.563
cxcr4achemokine (C-X-C motif) receptor 4a0.559
top2atopoisomerase (DNA) II alpha0.545
pea3ETS-domain transcription factor pea30.544
wnt1wingless-type MMTV integration site family, member 10.538
snrpd1small nuclear ribonucleoprotein D1 polypeptide0.537
myod1myogenic differentiation 10.530
hoxa9bhomeo box A9b0.529
six4bsine oculis homeobox homolog 4b0.528
snrpcsmall nuclear ribonucleoprotein polypeptide C0.524
rps3aribosomal protein S3A0.500
sae1SUMO1 activating enzyme subunit 10.497
nolc1nucleolar and coiled-body phosphoprotein 10.491
rpl7ribosomal protein L70.477
ccnb1cyclin B10.470
piwil1piwi-like 1 (Drosophila)0.461
smad9MAD homolog 9 (Drosophila)0.444
rpl13ribosomal protein L130.436
smyhc1slow myosin heavy chain 10.425
tp53tumor protein p530.414
hey1hairy/enhancer-of-split related with YRPW motif 10.411
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.404
mapk3mitogen-activated protein kinase 30.400
snrnp70small nuclear ribonucleoprotein 70 (U1)0.385
ube2iubiquitin-conjugating enzyme E2I0.384
actn2actinin, alpha 20.383
rpl6ribosomal protein L60.378
hhiphedgehog interacting protein0.378
pold1polymerase (DNA directed), delta 1, catalytic subunit0.377
u2af1U2(RNU2) small nuclear RNA auxiliary factor 10.375
wnt4awingless-type MMTV integration site family, member 4a0.370
spry2sprouty homolog 20.367
bcl2l1bcl2-like 10.365
sass6spindle assembly 6 homolog (C. elegans)0.365
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.364
rps8aribosomal protein S8a0.362
notch3notch homolog 30.362
lhx1aLIM homeobox 1a0.354
gli1GLI-Kruppel family member 10.345
rpl23aribosomal protein L23a0.345
eya1eyes absent homolog 10.344
notch1anotch homolog 1a0.335
rps5ribosomal protein S50.335
dusp6dual specificity phosphatase 60.335
smc3structural maintenance of chromosomes 30.335
rpl35ribosomal protein L350.334
mibmind bomb0.332
ctnnb1catenin (cadherin-associated protein), beta 10.332
map2k4amitogen-activated protein kinase kinase 4a0.323
cxcr4bchemokine (C-X-C motif), receptor 4b0.320
ccna2cyclin A20.317
ncapd2non-SMC condensin I complex, subunit D20.315
dnmt5DNA (cytosine-5-)-methyltransferase 50.311
rpl36ribosomal protein L360.310
sf3b1splicing factor 3b, subunit 10.308
rps18ribosomal protein S180.307
dtldenticleless homolog (Drosophila)0.307
sox4aSRY-box containing gene 4a0.301
myf5myogenic factor 50.300
foxj1aforkhead box J1a0.298
rps11ribosomal protein S110.295
tgfb3transforming growth factor, beta 30.286
dag1dystroglycan 10.285
pax6bpaired box gene 6b0.275
snrnp27small nuclear ribonucleoprotein 27 (U4/U6.U5)0.275
tal1T-cell acute lymphocytic leukemia 10.269
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.267
sall4sal-like 4 (Drosophila)0.266
ptch2patched 20.262
prkczprotein kinase C, zeta0.261
rpl4ribosomal protein L40.257
fbn2bfibrillin 2b0.253
ncapgnon-SMC condensin I complex, subunit G0.250
atoh1aatonal homolog 1a0.247
sox11aSRY-box containing gene 11a0.247
lmx1b.1LIM homeobox transcription factor 1, beta 10.246
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.244
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.243
epb41l5erythrocyte membrane protein band 4.1 like 50.238
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
npp-1Protein NPP-10.990
gpr-1Protein GPR-10.988
cye-1Protein CYE-10.970
goa-1Protein GOA-10.959
wrm-1Protein WRM-10.949
hgrs-1Protein HGRS-10.942
atn-1Protein ATN-10.941
gpr-2Protein GPR-20.925
hcp-1Protein HCP-10.917
par-5Protein PAR-50.915
dao-5Protein DAO-50.912
ran-1Protein RAN-10.901
cyk-4Protein CYK-40.900
inx-3Protein INX-30.885
lin-5Protein LIN-50.875
R11A8.7Protein R11A8.70.875
ndc-80Protein NDC-800.861
sas-5Protein SAS-50.854
zyg-9Protein ZYG-90.852
apr-1Protein APR-10.852
elt-6Protein ELT-60.849
cec-5Protein CEC-50.847
knl-1Protein KNL-10.844
spdl-1Protein SPDL-10.837
scc-3Protein SCC-30.824
skp-1Protein SKP-10.823
pmk-1Protein PMK-10.821
teg-4Protein TEG-40.820
D1081.8Protein D1081.80.820
rsa-1Protein RSA-10.813
brc-1Protein BRC-10.793
let-99Protein LET-990.784
rpl-18Protein RPL-180.779
mat-3Protein MAT-30.777
CELE_D1054.14Protein D1054.140.763
klp-19Protein KLP-190.762
rpl-7Protein RPL-70.762
mel-28Protein MEL-280.759
retr-1Protein RETR-10.755
rnr-1Protein RNR-10.749
jmjd-1.2Protein JMJD-1.20.747
cls-2Protein CLS-20.744
CELE_C56A3.8Protein C56A3.80.742
dna-2Protein DNA-20.742
kle-2Protein KLE-20.741
npp-3Protein NPP-30.739
hcp-2Protein HCP-20.737
mcm-5Protein MCM-50.732
cgh-1Protein CGH-10.732
xpo-2Protein XPO-20.731
lin-12Protein LIN-120.730
tbb-1Protein TBB-10.723
tbg-1Protein TBG-10.723
mig-5Protein MIG-50.720
spt-5Protein SPT-50.713
mom-2Protein MOM-20.713
tam-1Protein TAM-10.712
him-10Protein HIM-100.710
ZK430.7Protein ZK430.70.709
bub-1Protein BUB-10.707
egl-18Protein EGL-180.704
prp-8Protein PRP-80.700
zyg-11Protein ZYG-110.699
rsa-2Protein RSA-20.689
mex-5Protein MEX-50.688
set-2Protein SET-20.688
klp-16Protein KLP-160.686
rars-1Protein RARS-10.679
set-1Protein SET-10.677
swsn-7Protein SWSN-70.676
cku-80Protein CKU-800.669
adr-1Protein ADR-10.668
rla-0Protein RLA-00.662
Y49F6B.9Protein Y49F6B.90.657
pri-1Protein PRI-10.650
mix-1Protein MIX-10.649
pal-1Protein PAL-10.645
tim-1Protein TIM-10.645
mex-3Protein MEX-30.640
rpa-2Protein RPA-20.639
him-1Protein HIM-10.636
rpl-6Protein RPL-60.635
T08A11.2Protein T08A11.20.633
knl-2Protein KNL-20.633
hpl-2Protein HPL-20.631
smc-4Protein SMC-40.630
H21P03.2Protein H21P03.20.628
rskn-1Protein RSKN-10.627
rpl-14Protein RPL-140.625
mag-1Protein MAG-10.624
rpl-4Protein RPL-40.624
ZC434.8Protein ZC434.80.624
attf-2Protein ATTF-20.624
F22G12.5Protein F22G12.50.622
hmg-4Protein HMG-40.620
rps-5Protein RPS-50.619
rme-2Protein RME-20.619
F35F11.1Protein F35F11.10.616
brd-1Protein BRD-10.613
gla-3Protein GLA-30.610
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pfn1profilin 10.906
Arf6ADP-ribosylation factor 60.782
Eif4heukaryotic translation initiation factor 4H0.674
Tpm3tropomyosin 3, gamma0.572
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.505
Fgfr1Fibroblast growth factor receptor 10.470
Exoc5exocyst complex component 50.469
Tpm4tropomyosin 40.466
Mapk1mitogen activated protein kinase 10.384
Top2atopoisomerase (DNA) II alpha0.380
Hk1hexokinase 10.372
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.365
Cdk2cyclin dependent kinase 20.317
Tubb5tubulin, beta 50.314
Ap2m1adaptor-related protein complex 2, mu 1 subunit0.298
Stip1stress-induced phosphoprotein 10.296
Jak2Janus kinase 20.284
Taok1TAO kinase 10.273
Mapre1microtubule-associated protein, RP/EB family, member 10.268
Csnk2bcasein kinase 2, beta polypeptide0.266
Actr3ARP3 actin-related protein 3 homolog (yeast)0.264
Mapk3mitogen activated protein kinase 30.254
Ptbp1polypyrimidine tract binding protein 10.229
Impdh2IMP (inosine monophosphate) dehydrogenase 20.228
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.220
Cenpicentromere protein I0.210
Cand1cullin-associated and neddylation-dissociated 10.207
Ccnd1cyclin D10.198
Dnm1ldynamin 1-like0.196
Ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.196
Id3inhibitor of DNA binding 30.185
Rap1bRAP1B, member of RAS oncogene family0.185
Ptgs2prostaglandin-endoperoxide synthase 20.181
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.177
Eef2eukaryotic translation elongation factor 20.177
Myh9myosin, heavy chain 9, non-muscle0.176
Fkbp1aFK506 binding protein 1a0.172
Gja5gap junction protein, alpha 50.167
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.165
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.164
Mdm2Mdm2 p53 binding protein homolog (mouse)0.164
Dlgap5discs, large (Drosophila) homolog-associated protein 50.159
Cfpcomplement factor properdin0.158
Dctn4dynactin 40.155
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.152
Rhoaras homolog gene family, member A0.152
CnbpCCHC-type zinc finger, nucleic acid binding protein0.150
Stxbp1syntaxin binding protein 10.145
Dnm1dynamin 10.144
Csnk1dcasein kinase 1, delta0.143
Btg2BTG family, member 20.143
Ptmaprothymosin alpha0.142
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.139
Myo1bmyosin Ib0.138
Gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2 like 10.136
Casp2caspase 20.134
OgtO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.130
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.130
Csnk1g3casein kinase 1, gamma 30.129
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.128
Actbactin, beta0.127
Myo1cmyosin IC0.124
Tspyl1TSPY-like 10.124
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.124
Pcnaproliferating cell nuclear antigen0.123
Nfianuclear factor I/A0.121
Ccnd3cyclin D30.121
Tmsb10thymosin, beta 100.121
Sf3a3splicing factor 3a, subunit 30.119
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.118
Akt1v-akt murine thymoma viral oncogene homolog 10.117
Nap1l1nucleosome assembly protein 1-like 10.114
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.112
JunJun oncogene0.111
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.111
Acta2smooth muscle alpha-actin0.111
Rpl23ribosomal protein L230.110
Ptov1prostate tumor overexpressed 10.110
Rps5ribosomal protein S50.108
Tpm2tropomyosin 2, beta0.107
Phka1phosphorylase kinase, alpha 10.106
Gjb3gap junction protein, beta 30.106
Dynll1dynein light chain LC8-type 10.106
Ubcubiquitin C0.105
Cdk4cyclin-dependent kinase 40.105
Brsk1BR serine/threonine kinase 10.104
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.104
Nup88nucleoporin 880.104
Mpripmyosin phosphatase Rho interacting protein0.104
Stxbp5syntaxin binding protein 5 (tomosyn)0.103
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.103
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.103
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.103
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.102
Smad2SMAD family member 20.101
Rpl11ribosomal protein L110.100
Lifrleukemia inhibitory factor receptor alpha0.099
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism