The network for 'dorsal ventral axon guidance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dorsal ventral axon guidance

The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.

Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-73Protein UNC-730.881
mig-2Protein MIG-20.487
ced-10Protein CED-100.449
unc-6Protein UNC-60.412
rig-6Protein RIG-60.412
syg-1Protein SYG-10.362
ceh-20Protein CEH-200.352
unc-9Protein UNC-90.301
ina-1Protein INA-10.294
unc-5Protein UNC-50.232
sdn-1Protein SDN-10.177
ncam-1Protein NCAM-10.176
gap-2Protein GAP-20.161
lin-17Protein LIN-170.134
pqe-1Protein PQE-10.133
ptp-3Protein PTP-30.129
F21C10.7Protein F21C10.70.123
cwn-1Protein CWN-10.115
jmjc-1Protein JMJC-10.113
trim-9Protein TRIM-90.113
tag-241Protein TAG-2410.098
nud-2Protein NUD-20.094
zoo-1Protein ZOO-10.088
sax-3Protein SAX-30.083
gmeb-1Protein GMEB-10.082
T28F4.1Protein T28F4.10.082
mab-5Protein MAB-50.082
sem-5Protein SEM-50.069
unc-41Protein UNC-410.068
kin-32Protein KIN-320.066
T24B8.3Protein T24B8.30.065
kal-1Protein KAL-10.064
F36A2.13Protein F36A2.130.063
syd-9Protein SYD-90.062
ten-1Protein TEN-10.057
ttyh-1Protein TTYH-10.057
C11E4.6Protein C11E4.60.046
gck-2Protein GCK-20.044
F22D3.2Protein F22D3.20.042
atat-2Protein ATAT-20.041
tir-1Protein TIR-10.041
unc-53Protein UNC-530.041
cst-1Protein CST-10.039
F09A5.4Protein F09A5.40.039
max-1Protein MAX-10.039
F53B3.5Protein F53B3.50.038
set-18Protein SET-180.038
F19C7.8Protein F19C7.80.038
daf-19Protein DAF-190.036
CELE_C33A12.3Protein C33A12.30.034
unc-112Protein UNC-1120.034
T12E12.3Protein T12E12.30.033
sad-1Protein SAD-10.033
somi-1Protein SOMI-10.032
let-19Protein LET-190.032
set-25Protein SET-250.032
T02E9.5Protein T02E9.50.031
unc-120Protein UNC-1200.031
unc-108Protein UNC-1080.030
etr-1Protein ETR-10.030
lam-2Protein LAM-20.030
hmg-11Protein HMG-110.029
unc-68Protein UNC-680.029
rig-3Protein RIG-30.029
slo-1Protein SLO-10.028
R90.1Protein R90.10.028
afd-1Protein AFD-10.026
sel-7Protein SEL-70.026
nlr-1Protein NLR-10.026
efn-2Protein EFN-20.026
pat-3Protein PAT-30.026
rnp-7Protein RNP-70.026
klp-11Protein KLP-110.025
ugt-57Protein UGT-570.025
let-60Protein LET-600.025
plx-2Protein PLX-20.025
CELE_T13H5.1Protein T13H5.10.025
ctn-1Protein CTN-10.025
ddr-2Protein DDR-20.024
epi-1Protein EPI-10.024
ast-1Protein AST-10.024
kpc-1Protein KPC-10.024
stn-1Protein STN-10.024
pqn-42Protein PQN-420.024
F57F4.4Protein F57F4.40.023
F29A7.4Protein F29A7.40.023
C32E8.3Protein C32E8.30.023
CELE_B0285.3Protein B0285.30.022
F11D5.1Protein F11D5.10.022
T25B9.3Protein T25B9.30.022
fmi-1Protein FMI-10.021
R04B3.2Protein R04B3.20.021
CELE_C01B10.9Protein C01B10.90.021
F54D8.6Protein F54D8.60.021
F58H1.5Protein F58H1.50.021
mig-10Protein MIG-100.021
F32D8.3Protein F32D8.30.020
unc-36Protein UNC-360.020
arl-3Protein ARL-30.020
rap-1Protein RAP-10.020
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
roboroundabout0.998
trioCG18214 gene product from transcript CG18214-RA0.997
lealeak0.991
enaenabled0.979
dockdreadlocks0.964
Sema-1aCG18405 gene product from transcript CG18405-RD0.933
commcommissureless0.923
lolalongitudinals lacking0.819
AblAbl tyrosine kinase0.793
frafrazzled0.750
tutlturtle0.719
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.715
DscamDown syndrome cell adhesion molecule0.595
slislit0.587
CadNCadherin-N0.460
prosprospero0.413
Rac1CG2248 gene product from transcript CG2248-RA0.409
SoxNSoxNeuro0.390
pod1CG4532 gene product from transcript CG4532-RF0.386
Trim9CG31721 gene product from transcript CG31721-RB0.379
drlderailed0.376
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.312
stanstarry night0.296
plexBplexin B0.288
elavembryonic lethal abnormal vision0.274
kuzkuzbanian0.273
reporeversed polarity0.255
SdcSyndecan0.242
rictorrapamycin-insensitive companion of Tor0.239
Ptp69DProtein tyrosine phosphatase 69D0.236
Cdc42CG12530 gene product from transcript CG12530-RA0.233
mbcmyoblast city0.222
spensplit ends0.220
Wnt5Wnt oncogene analog 50.216
plexAplexin A0.187
otkoff-track0.174
mewmultiple edematous wings0.165
HemHEM-protein0.164
Rho1CG8416 gene product from transcript CG8416-RB0.151
LIMK1LIM-kinase10.150
midmidline0.148
stumpsCG31317 gene product from transcript CG31317-RC0.143
simsingle-minded0.140
sqzsqueeze0.140
babobaboon0.135
retnretained0.132
vndventral nervous system defective0.132
CapsCalcium activated protein for secretion0.132
unc-5CG8166 gene product from transcript CG8166-RA0.131
nerfin-1nervous fingers 10.128
NetBNetrin-B0.125
shotshort stop0.122
NrgNeuroglian0.119
chicchickadee0.115
Fas2Fasciclin 20.099
Ten-mTenascin major0.098
ttktramtrack0.097
rokRho-kinase0.097
gcmglial cells missing0.096
robo3CG5423 gene product from transcript CG5423-RA0.095
jingCG9397 gene product from transcript CG9397-RI0.087
emsempty spiracles0.078
l(2)k16918lethal (2) k169180.067
tuptailup0.062
pntpointed0.061
Nrx-IVNeurexin IV0.059
miramiranda0.058
nvynervy0.058
PakPAK-kinase0.058
Sema-2aCG4700 gene product from transcript CG4700-RC0.057
SmoxSmad on X0.053
MicalMolecule interacting with CasL0.049
sidesidestep0.047
EphrinCG1862 gene product from transcript CG1862-RA0.046
hkbhuckebein0.045
G-oalpha47AG protein oalpha 47A0.044
wbwing blister0.042
LanALaminin A0.042
exexextra-extra0.042
zfh1Zn finger homeodomain 10.039
fogfolded gastrulation0.039
NrtNeurotactin0.038
ococelliless0.038
aopanterior open0.037
Fas3Fasciclin 30.037
EphEph receptor tyrosine kinase0.037
par-1CG8201 gene product from transcript CG8201-RA0.036
CG9650CG9650 gene product from transcript CG9650-RG0.034
CG12424CG12424 gene product from transcript CG12424-RC0.034
fasfaint sausage0.033
jebjelly belly0.033
NetANetrin-A0.032
argosCG4531 gene product from transcript CG4531-RA0.030
Ptp52FCG18243 gene product from transcript CG18243-RB0.030
InRInsulin-like receptor0.030
hipkhomeodomain interacting protein kinase0.030
Nedd4CG42279 gene product from transcript CG42279-RJ0.029
Arf79FADP ribosylation factor 79F0.029
form3formin 30.028
taitaiman0.026
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Robo1roundabout homolog 1 (Drosophila)1.000
Slit3slit homolog 3 (Drosophila)1.000
Slit2slit homolog 2 (Drosophila)1.000
Robo2roundabout homolog 2 (Drosophila)1.000
Gli2GLI-Kruppel family member GLI20.973
Dccdeleted in colorectal carcinoma0.972
Vaspvasodilator-stimulated phosphoprotein0.970
Gli3GLI-Kruppel family member GLI30.968
Unc5cunc-5 homolog C (C. elegans)0.959
Slit1slit homolog 1 (Drosophila)0.935
Enahenabled homolog (Drosophila)0.902
Tbx4T-box 40.900
Bhlhe22basic helix-loop-helix family, member e220.853
Shhsonic hedgehog0.847
Ntn1netrin 10.809
EvlEna-vasodilator stimulated phosphoprotein0.800
Pitx1paired-like homeodomain transcription factor 10.791
Fgf8fibroblast growth factor 80.739
Lmx1bLIM homeobox transcription factor 1 beta0.696
Isl1ISL1 transcription factor, LIM/homeodomain0.692
Tbx3T-box 30.590
Zfpm2zinc finger protein, multitype 20.464
Msx2homeobox, msh-like 20.458
Pitx2paired-like homeodomain transcription factor 20.456
Fgfr2fibroblast growth factor receptor 20.436
En1engrailed 10.401
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.394
Otx2orthodenticle homolog 2 (Drosophila)0.387
Sox11SRY-box containing gene 110.367
Lhx3LIM homeobox protein 30.355
Ephb2Eph receptor B20.342
Foxc1forkhead box C10.334
Pax6paired box gene 60.328
Twist2twist homolog 2 (Drosophila)0.319
Mark1MAP/microtubule affinity-regulating kinase 10.318
Mmp16matrix metallopeptidase 160.294
Mesp1mesoderm posterior 10.279
Hoxa13homeobox A130.275
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.267
Fgf10fibroblast growth factor 100.267
Smpd3sphingomyelin phosphodiesterase 3, neutral0.255
Wdr1WD repeat domain 10.254
Bmpr1abone morphogenetic protein receptor, type 1A0.245
Grb10growth factor receptor bound protein 100.233
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.227
Pax3paired box gene 30.225
Sox9SRY-box containing gene 90.215
Gata4GATA binding protein 40.210
Auts2autism susceptibility candidate 20.204
Emx1empty spiracles homolog 1 (Drosophila)0.198
Msnmoesin0.194
Nfatc4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 40.193
Hand1heart and neural crest derivatives expressed transcript 10.192
Ctnnb1catenin (cadherin associated protein), beta 10.190
Fbn2fibrillin 20.189
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.185
Tbx1T-box 10.179
Foxh1forkhead box H10.167
Cdh4cadherin 40.162
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.162
Tead3TEA domain family member 30.159
Drd2dopamine receptor D20.159
Sall4sal-like 4 (Drosophila)0.156
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.154
Rhogras homolog gene family, member G0.151
Ebf3early B-cell factor 30.149
Ptk7PTK7 protein tyrosine kinase 70.148
Foxc2forkhead box C20.147
Nognoggin0.145
Zic3zinc finger protein of the cerebellum 30.141
Efsembryonal Fyn-associated substrate0.138
Dlk1delta-like 1 homolog (Drosophila)0.136
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.134
Efna2ephrin A20.132
Tcfap2ctranscription factor AP-2, gamma0.130
Myo10myosin X0.128
Cbln1cerebellin 1 precursor protein0.128
Gli1GLI-Kruppel family member GLI10.125
Capn6calpain 60.124
Lef1lymphoid enhancer binding factor 10.119
Shox2short stature homeobox 20.119
Tgfb2transforming growth factor, beta 20.118
Col22a1collagen, type XXII, alpha 10.115
Myf5myogenic factor 50.113
Ncam1neural cell adhesion molecule 10.111
Obsl1obscurin-like 10.110
Arhgap1Rho GTPase activating protein 10.108
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.107
Cotl1coactosin-like 1 (Dictyostelium)0.106
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.105
Srgap1SLIT-ROBO Rho GTPase activating protein 10.103
Tcfap2atranscription factor AP-2, alpha0.103
Hoxd13homeobox D130.100
Dbx1developing brain homeobox 10.100
Ednraendothelin receptor type A0.099
Gpc6glypican 60.098
Vegfavascular endothelial growth factor A0.097
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.096
Nodalnodal0.092
Gbx2gastrulation brain homeobox 20.091
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Camk2n2calcium/calmodulin-dependent protein kinase II inhibitor 20.735
Foxd4forkhead box D40.266
Chrnb2cholinergic receptor, nicotinic, beta 2 (neuronal)0.182
Robo1roundabout homolog 1 (Drosophila)0.182
Foxe3forkhead box E30.181
Hpcal4hippocalcin-like 40.175
Barhl2BarH-like homeobox 20.166
Mipmajor intrinsic protein of lens fiber0.133
Hmga2high mobility group AT-hook 20.128
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.085
Galr3galanin receptor 30.072
Crybb2crystallin, beta B20.069
Slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.068
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.066
Gjb4gap junction protein, beta 40.063
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.063
Chrm1cholinergic receptor, muscarinic 10.062
Cntfrciliary neurotrophic factor receptor0.061
Runx3runt-related transcription factor 30.060
Lim2lens intrinsic membrane protein 20.060
Hes3hairy and enhancer of split 3 (Drosophila)0.054
Dccdeleted in colorectal carcinoma0.048
Epha8Eph receptor A80.046
Begainbrain-enriched guanylate kinase-associated0.046
Unc5aunc-5 homolog A (C. elegans)0.045
Pgcprogastricsin (pepsinogen C)0.044
Crybb3crystallin, beta B30.043
Gpr182G protein-coupled receptor 1820.040
Gcm1glial cells missing homolog 1 (Drosophila)0.039
Sdc3syndecan 30.038
Foxi2forkhead box I20.037
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.037
Pou6f1POU class 6 homeobox 10.036
Grm5glutamate receptor, metabotropic 50.036
Scarf2scavenger receptor class F, member 20.036
Cnn1calponin 1, basic, smooth muscle0.035
Syn1synapsin I0.035
Sgp158proline-rich glycoprotein (sgp158)0.035
Sema6csema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C0.035
Gdf11growth differentiation factor 110.033
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.033
Prlhprolactin releasing hormone0.033
Lin7blin-7 homolog b (C. elegans)0.032
Nr0b2nuclear receptor subfamily 0, group B, member 20.031
Pyypeptide YY (mapped)0.030
LOC679931hypothetical protein LOC6799310.030
Thpothrombopoietin0.030
Gna11guanine nucleotide binding protein, alpha 110.030
Gria1glutamate receptor, ionotropic, AMPA 10.029
Aanatarylalkylamine N-acetyltransferase0.028
Nxph3neurexophilin 30.028
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.026
Ttntitin0.026
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.025
Bhlha15basic helix-loop-helix family, member a150.025
Cryba2crystallin, beta A20.024
F2rl3coagulation factor II (thrombin) receptor-like 30.023
Nxph4neurexophilin 40.023
Grk4G protein-coupled receptor kinase 40.023
Ppp1r9aprotein phosphatase 1, regulatory (inhibitor) subunit 9A0.023
Fgf22fibroblast growth factor 220.023
Atp2c1ATPase, Ca++ transporting, type 2C, member 10.022
RGD1305627hypothetical LOC3144670.022
Dlg4discs, large homolog 4 (Drosophila)0.021
Ghsrgrowth hormone secretagogue receptor0.021
Matkmegakaryocyte-associated tyrosine kinase0.021
Tgfb3transforming growth factor, beta 30.021
Aqp5aquaporin 50.021
Myh1myosin, heavy polypeptide 1, skeletal muscle, adult0.021
Pgrprogesterone receptor0.021
Pdcphosducin0.020
Foxd1forkhead box D10.020
Myh13myosin, heavy chain 13, skeletal muscle0.020
Acracrosin0.020
Zcchc3zinc finger, CCHC domain containing 30.020
Mgat3mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase0.020
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.020
Mapk15mitogen-activated protein kinase 150.019
Hapln1hyaluronan and proteoglycan link protein 10.019
Clec11aC-type lectin domain family 11, member a0.019
Mapk4mitogen-activated protein kinase 40.019
Lmod1leiomodin 1 (smooth muscle)0.019
Nlgn3neuroligin 30.019
Aardalanine and arginine rich domain containing protein0.019
Bvesblood vessel epicardial substance0.018
Galntl1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 10.018
Nlgn2neuroligin 20.018
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.018
Dpp6dipeptidylpeptidase 60.018
Fabp6fatty acid binding protein 6, ileal0.018
Sox17SRY (sex determining region Y)-box 170.018
Aqp2aquaporin 2 (collecting duct)0.018
Megf6multiple EGF-like-domains 60.018
Rbp2retinol binding protein 2, cellular0.018
Crhbpcorticotropin releasing hormone binding protein0.018
Prxperiaxin0.017
Esr2estrogen receptor 2 (ER beta)0.017
Amhanti-Mullerian hormone0.017
Crybb1crystallin, beta B10.017
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism