The network for 'respiratory electron transport chain' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

respiratory electron transport chain

A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.

NameDescriptionProbabilityFunc Analog Organism
ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.969
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.799
uqcrbubiquinol-cytochrome c reductase binding protein0.790
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.770
etfaelectron-transfer-flavoprotein, alpha polypeptide0.665
ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.571
pdhbpyruvate dehydrogenase (lipoamide) beta0.570
zgc:111961zgc:1119610.568
uqcrc1ubiquinol-cytochrome c reductase core protein I0.556
chchd2coiled-coil-helix-coiled-coil-helix domain containing 20.543
ndufb8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 80.472
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.453
ivdisovaleryl Coenzyme A dehydrogenase0.447
slc25a11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.409
zgc:112340zgc:1123400.395
pdha1apyruvate dehydrogenase (lipoamide) alpha 1a0.374
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.341
ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.328
zgc:73329zgc:733290.313
cox7ccytochrome c oxidase, subunit VIIc0.312
cox8acytochrome c oxidase subunit 8a0.247
aco2aconitase 2, mitochondrial0.231
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.230
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.227
zgc:73198zgc:731980.223
ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.221
cox4i1cytochrome c oxidase subunit IV isoform 10.205
uqcrc2bubiquinol-cytochrome c reductase core protein IIb0.203
ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.195
gbasglioblastoma amplified sequence0.153
cox5abcytochrome c oxidase subunit Vab0.146
zgc:66391zgc:663910.138
sarsseryl-tRNA synthetase0.124
suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.123
acadlacyl-Coenzyme A dehydrogenase, long chain0.120
ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 60.117
uqcrc2aubiquinol-cytochrome c reductase core protein IIa0.115
hsp90a.2heat shock protein 90-alpha 20.112
lrpprcleucine-rich PPR-motif containing0.111
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.110
atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.102
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.099
got2aglutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)0.097
cyc1cytochrome c-10.090
LOC100333064cytochrome b-c1 complex subunit 9-like0.082
idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.075
zgc:77820zgc:778200.075
zgc:100908zgc:1009080.074
ATP8ATP synthase 80.072
sod1superoxide dismutase 1, soluble0.072
ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex 50.071
si:ch211-239j9.2si:ch211-239j9.20.071
LOC402883hypothetical protein LOC4028830.065
zgc:114172zgc:1141720.064
cox5aacytochrome c oxidase subunit Vaa0.063
dlstdihydrolipoamide S-succinyltransferase0.062
cox7a2cytochrome c oxidase, subunit VIIa 20.062
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.060
prdx3peroxiredoxin 30.059
slc2a12solute carrier family 2 (facilitated glucose transporter), member 120.056
ndufa10NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 100.053
ndufs5NADH dehydrogenase (ubiquinone) Fe-S protein 50.053
sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.052
arfip2bADP-ribosylation factor interacting protein 2b0.048
gpx4aglutathione peroxidase 4a0.048
atp5lATP synthase, H+ transporting, mitochondrial F0 complex, subunit g0.047
acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.045
tpi1btriosephosphate isomerase 1b0.045
acaa2acetyl-CoA acyltransferase 20.044
ndufa9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 90.043
ocrloculocerebrorenal syndrome of Lowe0.042
tardbpTAR DNA binding protein0.042
tp53tumor protein p530.041
slco1d1solute carrier organic anion transporter family, member 1D10.038
surf1surfeit 10.037
zgc:64133zgc:641330.037
psip1PC4 and SFRS1 interacting protein 10.037
ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.035
chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.035
zgc:110155zgc:1101550.034
slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.034
LOC100332034NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like0.034
LOC100536349lysophospholipid acyltransferase LPCAT4-like0.033
phbprohibitin0.033
golga5golgi autoantigen, golgin subfamily a, 50.032
amtaminomethyltransferase0.032
zgc:92631zgc:926310.030
mibmind bomb0.029
zgc:92030zgc:920300.029
atp5gATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)0.029
pccbpropionyl Coenzyme A carboxylase, beta polypeptide0.028
si:ch211-236l14.3si:ch211-236l14.30.028
cacnb2acalcium channel, voltage-dependent, beta 2a0.028
uqcr11ubiquinol-cytochrome c reductase, complex III subunit XI0.028
wdr45WD repeat domain 450.027
lamb2laminin, beta 2 (laminin S)0.027
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.027
ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)0.027
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.026
mutmethylmalonyl Coenzyme A mutase0.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
prdx-3Protein PRDX-30.063
clpp-1Protein CLPP-10.045
ucr-1Protein UCR-10.036
CELE_F59C6.5Protein F59C6.50.034
dlst-1Protein DLST-10.025
kat-1Protein KAT-10.022
R07H5.8Protein R07H5.80.020
rpia-1Protein RPIA-10.017
Y53G8AL.2Protein Y53G8AL.20.017
C30H6.7Protein C30H6.70.016
F26E4.6Protein F26E4.60.016
atp-5Protein ATP-50.016
F42G8.10Protein F42G8.100.015
F58F12.1Protein F58F12.10.015
F45H10.2Protein F45H10.20.014
immt-1Protein IMMT-10.013
nuo-2Protein NUO-20.012
R53.5Protein R53.50.011
F36A2.7Protein F36A2.70.011
CELE_Y69A2AR.18Protein Y69A2AR.180.011
C34B2.8Protein C34B2.80.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dj-1betaCG1349 gene product from transcript CG1349-RA0.324
SdhBSuccinate dehydrogenase B0.313
ND75NADH:ubiquinone reductase 75kD subunit precursor0.249
Sod2Superoxide dismutase 2 (Mn)0.246
CG9140CG9140 gene product from transcript CG9140-RA0.123
CG12079CG12079 gene product from transcript CG12079-RA0.110
ND42NADH:ubiquinone reductase 42kD subunit precursor0.106
CG3683CG3683 gene product from transcript CG3683-RC0.091
ATPsyn-bATP synthase, subunit b0.091
AconAconitase0.087
l(2)35Dilethal (2) 35Di0.082
CG6020CG6020 gene product from transcript CG6020-RA0.078
EnoEnolase0.077
CG12203CG12203 gene product from transcript CG12203-RA0.061
CG8818CG8818 gene product from transcript CG8818-RA0.060
SdhCSuccinate dehydrogenase C0.058
CG3731CG3731 gene product from transcript CG3731-RA0.051
l(3)03670lethal (3) 036700.049
OscpOligomycin sensitivity-conferring protein0.044
TpiTriose phosphate isomerase0.038
CG5703CG5703 gene product from transcript CG5703-RA0.038
porinCG6647 gene product from transcript CG6647-RA0.036
l(1)G0334lethal (1) G03340.031
ATPsyn-gammaATP synthase-gamma chain0.029
ScsalphaSuccinyl coenzyme A synthetase alpha subunit0.027
l(3)neo18lethal (3) neo180.025
Gpo-1Glycerophosphate oxidase-10.025
CG10664CG10664 gene product from transcript CG10664-RB0.022
PgkPhosphoglycerate kinase0.021
bdgbedraggled0.019
NP15.6CG6008 gene product from transcript CG6008-RA0.018
CG11876CG11876 gene product from transcript CG11876-RA0.017
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.017
CG9399CG9399 gene product from transcript CG9399-RC0.017
CG3192CG3192 gene product from transcript CG3192-RA0.016
CG9350CG9350 gene product from transcript CG9350-RA0.016
CG30415CG30415 gene product from transcript CG30415-RA0.015
Prx5Peroxiredoxin 50.014
CG2076CG2076 gene product from transcript CG2076-RA0.014
l(1)G0156lethal (1) G01560.013
CG5548CG5548 gene product from transcript CG5548-RA0.013
levyCG17280 gene product from transcript CG17280-RA0.012
kermitCG11546 gene product from transcript CG11546-RB0.012
CG10219CG10219 gene product from transcript CG10219-RA0.012
Mlc2Myosin light chain 20.012
CG3321CG3321 gene product from transcript CG3321-RC0.011
SsadhSuccinic semialdehyde dehydrogenase0.011
PgiPhosphoglucose isomerase0.011
CG6439CG6439 gene product from transcript CG6439-RA0.010
Cyt-c-pCytochrome c proximal0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HDAC2histone deacetylase 20.683
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.613
NDUFS7NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)0.517
UQCRC1ubiquinol-cytochrome c reductase core protein I0.232
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.216
COX5Acytochrome c oxidase subunit Va0.204
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.172
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.157
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.126
COX6Ccytochrome c oxidase subunit VIc0.089
COX5Bcytochrome c oxidase subunit Vb0.084
NDUFB1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa0.080
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.074
UQCRC2ubiquinol-cytochrome c reductase core protein II0.072
UQCRHubiquinol-cytochrome c reductase hinge protein0.059
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.058
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.055
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.048
ESRRGestrogen-related receptor gamma0.043
PPARGperoxisome proliferator-activated receptor gamma0.035
COX7Bcytochrome c oxidase subunit VIIb0.033
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.033
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.031
IMMTinner membrane protein, mitochondrial0.028
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.024
NDUFA9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa0.022
SIN3ASIN3 homolog A, transcription regulator (yeast)0.022
COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)0.022
NDUFB5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa0.021
NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa0.020
HDAC1histone deacetylase 10.018
NDUFA4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa0.017
SUCLA2succinate-CoA ligase, ADP-forming, beta subunit0.013
FBXO7F-box protein 70.012
COX7A2cytochrome c oxidase subunit VIIa polypeptide 2 (liver)0.012
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.011
NDUFS4NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)0.011
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.011
NDUFA1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
COX4Cox4p0.994
SDH2Sdh2p0.993
RIP1Rip1p0.974
COR1Cor1p0.974
PET9Pet9p0.949
COX6Cox6p0.945
CYT1Cyt1p0.918
COX12Cox12p0.896
QCR2Qcr2p0.818
COX13Cox13p0.780
COX9Cox9p0.698
QCR9Qcr9p0.621
COX2Cox2p0.573
COX5ACox5ap0.564
SDH3Sdh3p0.490
QCR7Qcr7p0.470
QCR6Qcr6p0.427
INH1Inh1p0.410
CYC1Cyc1p0.385
QCR10Qcr10p0.355
ATP6Atp6p0.350
COX1Cox1p0.329
NDE1Nde1p0.281
QCR8Qcr8p0.277
ODC1Odc1p0.267
ACB1Acb1p0.195
COBCobp0.104
CIR2Cir2p0.081
SDH4Sdh4p0.078
YEL073Chypothetical protein0.077
ATP1Atp1p0.070
SHY1Shy1p0.068
AIM33Aim33p0.067
MDH1Mdh1p0.066
RPM2Rpm2p0.065
ATP18Atp18p0.065
HUG1Hug1p0.064
BI4Bi4p0.062
ATP2Atp2p0.062
MSS51Mss51p0.059
TIM11Tim11p0.054
CCP1Ccp1p0.053
COX8Cox8p0.053
YHR140Whypothetical protein0.052
PCL9Pcl9p0.052
ICS2Ics2p0.045
ATP3Atp3p0.042
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.041
COX15Cox15p0.036
COX3Cox3p0.035
AIM38Aim38p0.035
FRE7Fre7p0.034
AQY1Aqy1p0.034
SRD1Srd1p0.034
YLR264C-Ahypothetical protein0.033
ATP20Atp20p0.031
YAR028Whypothetical protein0.031
CUP1-1Cup1-1p0.030
ATP8Atp8p0.030
SDH1Sdh1p0.029
YLR040Chypothetical protein0.029
ATP16Atp16p0.028
HOR7Hor7p0.028
LEU2Leu2p0.028
YLR132Chypothetical protein0.027
YGL010Whypothetical protein0.027
YLR162Whypothetical protein0.027
COA3Coa3p0.027
CYC7Cyc7p0.026
ICY1Icy1p0.025
ARP10Arp10p0.025
URA3Ura3p0.025
MER1Mer1p0.024
YAR068Whypothetical protein0.024
AI1Ai1p0.024
YOL038C-Ahypothetical protein0.023
YGR205Whypothetical protein0.023
ARG8Arg8p0.023
ICL1Icl1p0.022
CCC1Ccc1p0.022
LEU5Leu5p0.022
YLR042Chypothetical protein0.022
YOR342Chypothetical protein0.022
CRP1Crp1p0.022
YML6Yml6p0.022
REE1Ree1p0.022
YIA6Yia6p0.022
HPF1Hpf1p0.021
CTR3Ctr3p0.021
YPR098Chypothetical protein0.021
FMT1Fmt1p0.021
TCM62Tcm62p0.021
YOL013W-Ahypothetical protein0.020
BSC1Bsc1p0.020
WSC4Wsc4p0.020
ZPS1Zps1p0.020
AUA1Aua1p0.019
SCM4Scm4p0.019
YBR013Chypothetical protein0.019
ADY2Ady2p0.019