The network for 'immune system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.993
kdrlkinase insert domain receptor like0.978
runx1runt-related transcription factor 10.976
tpm4tropomyosin 40.966
pea3ETS-domain transcription factor pea30.962
LOC566708FL cytokine receptor-like0.955
wnt10awingless-type MMTV integration site family, member 10a0.937
spns2spinster homolog 2 (Drosophila)0.937
shhasonic hedgehog a0.903
ikzf1IKAROS family zinc finger 1 (Ikaros)0.901
mpxmyeloid-specific peroxidase0.883
tbx16T-box gene 160.881
neo1neogenin 10.872
rhogbras homolog gene family, member Gb0.870
tie1endothelium-specific receptor tyrosine kinase 10.870
cmybtranscription factor cmyb0.863
hbbe1.1hemoglobin beta embryonic-1.10.857
edn1endothelin 10.850
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.845
tp53tumor protein p530.830
plcg1phospholipase C, gamma 10.830
sema3aasemaphorin 3aa0.828
hoxb2ahomeo box B2a0.825
trpv6transient receptor potential cation channel, subfamily V, member 60.809
mychmyelocytomatosis oncogene homolog0.809
rpl23aribosomal protein L23a0.805
pkd2polycystic kidney disease 20.801
tal1T-cell acute lymphocytic leukemia 10.793
ptprcprotein tyrosine phosphatase, receptor type, C0.793
gdnfglial cell derived neurotrophic factor0.788
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.780
pycardPYD and CARD domain containing0.778
alas2aminolevulinate, delta-, synthetase 20.777
slc4a1asolute carrier family 4, anion exchanger, member 1a0.775
pcnaproliferating cell nuclear antigen0.763
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.751
fzd10frizzled homolog 100.751
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.741
efnb2aephrin B2a0.731
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.724
tp63tumor protein p630.724
per3period homolog 3 (Drosophila)0.720
rab11fip4aRAB11 family interacting protein 4 (class II) a0.720
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.712
mstnbmyostatin b0.711
sfrp1asecreted frizzled-related protein 1a0.709
aplnrbapelin receptor b0.707
pitx2paired-like homeodomain transcription factor 20.705
wnt2bbwingless-type MMTV integration site family, member 2Bb0.703
rargaretinoic acid receptor gamma a0.701
gata1aGATA binding protein 1a0.692
runx2arunt-related transcription factor 2a0.681
cdh5cadherin 50.673
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.673
eomesaeomesodermin homolog a0.668
tfr1atransferrin receptor 1a0.664
osr1odd-skipped related 1 (Drosophila)0.662
s1pr2sphingosine-1-phosphate receptor 20.658
tgfb3transforming growth factor, beta 30.657
hnf1baHNF1 homeobox Ba0.638
gata3GATA-binding protein 30.637
metmet proto-oncogene (hepatocyte growth factor receptor)0.630
runx2brunt-related transcription factor 2b0.630
hoxb3ahomeo box B3a0.627
grem2gremlin 2, cysteine knot superfamily0.620
dkk1bdickkopf 1b0.619
wt1awilms tumor 1a0.618
mtmr8myotubularin related protein 80.616
fgf8afibroblast growth factor 8 a0.611
socs1suppressor of cytokine signaling 10.610
acvr1lactivin A receptor, type I like0.609
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.603
socs3asuppressor of cytokine signaling 3a0.601
hhiphedgehog interacting protein0.601
wnt11rwingless-type MMTV integration site family, member 11, related0.600
gh1growth hormone 10.595
junbjun B proto-oncogene0.594
LOC100151531zinc finger protein Gfi-1b-like0.594
osr2odd-skipped related 2 (Drosophila)0.591
wt1bwilms tumor 1b0.591
myd88myeloid differentiation primary response gene (88)0.590
nfe2nuclear factor, erythroid-derived 20.588
hand2heart and neural crest derivatives expressed transcript 20.586
npm1nucleophosmin 10.585
znfl2azinc finger-like gene 2a0.583
sox2SRY-box containing gene 20.580
tlr3toll-like receptor 30.574
vegfcvascular endothelial growth factor c0.570
ptprkprotein tyrosine phosphatase, receptor type, K0.569
cdx4caudal type homeo box transcription factor 40.566
rag1recombination activating gene 10.565
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.564
ldb2aLIM-domain binding factor 2a0.559
hoxa1ahomeo box A1a0.556
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PGRP-LCPeptidoglycan recognition protein LC0.999
EgfrEpidermal growth factor receptor0.997
DreddDeath related ced-3/Nedd2-like protein0.995
grassGram-positive Specific Serine protease0.987
BG4CG12297 gene product from transcript CG12297-RA0.985
SPESpatzle-Processing Enzyme0.980
Myd88CG2078 gene product from transcript CG2078-RA0.980
Rac1CG2248 gene product from transcript CG2248-RA0.980
drkdownstream of receptor kinase0.977
Cdc42CG12530 gene product from transcript CG12530-RA0.976
Akt1CG4006 gene product from transcript CG4006-RA0.975
PvrPDGF- and VEGF-receptor related0.964
AGO2Argonaute 20.962
Pi3K92ECG4141 gene product from transcript CG4141-RB0.959
Atg1Autophagy-specific gene 10.950
Sp7Serine protease 70.948
PGRP-SAPeptidoglycan recognition protein SA0.946
Mpk2CG5475 gene product from transcript CG5475-RB0.946
dcodiscs overgrown0.944
Pp2B-14DProtein phosphatase 2B at 14D0.944
Rac2CG8556 gene product from transcript CG8556-RA0.943
Spn27ASerpin 27A0.936
Dhc64CDynein heavy chain 64C0.929
snostrawberry notch0.929
aopanterior open0.928
ik2IkappaB kinase-like 20.923
ird5immune response deficient 50.918
Src42ASrc oncogene at 42A0.915
norpAno receptor potential A0.906
ird1immune response deficient 10.894
Fmr1CG6203 gene product from transcript CG6203-RC0.893
G-oalpha47AG protein oalpha 47A0.889
imdimmune deficiency0.885
CG11376CG11376 gene product from transcript CG11376-RA0.882
cicubitus interruptus0.878
slmbsupernumerary limbs0.875
shotshort stop0.870
CG32185CG32185 gene product from transcript CG32185-RA0.867
l(2)gllethal (2) giant larvae0.866
Tab2TAK1-associated binding protein 20.865
foxoforkhead box, sub-group O0.859
lunaCG33473 gene product from transcript CG33473-RB0.854
IrcImmune-regulated catalase0.849
trolterribly reduced optic lobes0.846
DptBDiptericin B0.835
proPO-A1prophenol oxidase A10.834
HsfHeat shock factor0.833
ShcSHC-adaptor protein0.832
GNBP3Gram-negative bacteria binding protein 30.830
E(spl)Enhancer of split0.830
PGRP-SDCG7496 gene product from transcript CG7496-RA0.826
LanALaminin A0.809
l(3)mbnlethal (3) malignant blood neoplasm0.805
AlkCG8250 gene product from transcript CG8250-RA0.799
HLHm7E(spl) region transcript m70.799
PtenCG5671 gene product from transcript CG5671-RB0.790
mib1mind bomb 10.787
Snr1Snf5-related 10.786
S6kRPS6-p70-protein kinase0.781
eaterCG6124 gene product from transcript CG6124-RB0.779
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-DaRT1 class II, locus Da0.963
Hckhemopoietic cell kinase0.951
Cd53Cd53 molecule0.917
Ccr5chemokine (C-C motif) receptor 50.911
RT1-BaRT1 class II, locus Ba0.903
Ptafrplatelet-activating factor receptor0.881
Ptprcprotein tyrosine phosphatase, receptor type, C0.858
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.853
Lyz2lysozyme 20.840
RT1-Db1RT1 class II, locus Db10.827
Casp1caspase 10.823
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.800
Prf1perforin 1 (pore forming protein)0.779
Cd37CD37 molecule0.761
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.757
Il1binterleukin 1 beta0.736
Il8rbinterleukin 8 receptor, beta0.728
Lcp1lymphocyte cytosolic protein 10.719
Mmp12matrix metallopeptidase 120.718
Ccl4chemokine (C-C motif) ligand 40.696
Fcnbficolin B0.687
Sellselectin L0.680
Cpb2carboxypeptidase B2 (plasma)0.669
Phkg1phosphorylase kinase, gamma 10.669
Cd68Cd68 molecule0.666
Klf6Kruppel-like factor 60.660
C5ar1complement component 5a receptor 10.659
P2ry14purinergic receptor P2Y, G-protein coupled, 140.657
Inpp5dinositol polyphosphate-5-phosphatase D0.654
Ly86lymphocyte antigen 860.652
Cd44Cd44 molecule0.646
Stat3signal transducer and activator of transcription 30.646
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.625
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.616
Ctsscathepsin S0.616
Cd247Cd247 molecule0.612
Ccr2chemokine (C-C motif) receptor 20.608
Cxcl2chemokine (C-X-C motif) ligand 20.607
Cxcr3chemokine (C-X-C motif) receptor 30.605
Prrx1paired related homeobox 10.602
Adora2aadenosine A2a receptor0.594
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.584
Vcam1vascular cell adhesion molecule 10.579
Ncf1neutrophil cytosolic factor 10.575
Gpnmbglycoprotein (transmembrane) nmb0.573
Prl8a7prolactin family 8, subfamily a, member 70.570
Actbactin, beta0.564
Neurl3neuralized homolog 3 (Drosophila)0.559
Cd4Cd4 molecule0.558
Itgamintegrin, alpha M0.537
Arl11ADP-ribosylation factor-like 110.536
Ccl2chemokine (C-C motif) ligand 20.531
Calcrcalcitonin receptor0.527
Ripk3receptor-interacting serine-threonine kinase 30.527
Foxd3forkhead box D30.527
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.524
Icam1intercellular adhesion molecule 10.517
Cybbcytochrome b-245, beta polypeptide0.515
Ccr1chemokine (C-C motif) receptor 10.509
Junbjun B proto-oncogene0.507
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.505
Tbxas1thromboxane A synthase 1, platelet0.504
Hcls1hematopoietic cell specific Lyn substrate 10.502
Igh-6immunoglobulin heavy chain 60.497
Apoa5apolipoprotein A-V0.491
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.491
Dnase1l3deoxyribonuclease 1-like 30.490
Dynll1dynein light chain LC8-type 10.488
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.483
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.476
RT1-N3RT1 class Ib, locus N30.474
Il2rginterleukin 2 receptor, gamma0.472
Gja4gap junction protein, alpha 40.472
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.470
LOC100364854similar to RIKEN cDNA A430107P09 gene-like0.468
Mpeg1macrophage expressed 10.466
Ptger2prostaglandin E receptor 2 (subtype EP2)0.464
Csf1colony stimulating factor 1 (macrophage)0.463
Cxcl10chemokine (C-X-C motif) ligand 100.455
Rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.455
Mrc1mannose receptor, C type 10.446
Tnni2troponin I type 2 (skeletal, fast)0.446
Il6interleukin 60.446
Aif1allograft inflammatory factor 10.446
Clec9aC-type lectin domain family 9, member a0.442
Napsanapsin A aspartic peptidase0.436
Adam17ADAM metallopeptidase domain 170.434
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.433
Igsf6immunoglobulin superfamily, member 60.433
FaslgFas ligand (TNF superfamily, member 6)0.430
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.425
Gzmkgranzyme K0.423
Tlr4toll-like receptor 40.422
Lcp2lymphocyte cytosolic protein 20.422
Fgd2FYVE, RhoGEF and PH domain containing 20.417
Itgb2integrin, beta 20.415
F2rl2coagulation factor II (thrombin) receptor-like 20.414
Cd3gCD3 molecule, gamma0.413
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism