The network for 'purine nucleoside triphosphate biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine nucleoside triphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.

NameDescriptionProbabilityFunc Analog Organism
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.525
aldocbaldolase C, fructose-bisphosphate, b0.394
hk1hexokinase 10.110
ldb3bLIM domain binding 3b0.109
pabpc1bpoly A binding protein, cytoplasmic 1 b0.089
pgk1phosphoglycerate kinase 10.077
eno1enolase 1, (alpha)0.073
atp5gATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)0.071
zgc:165344zgc:1653440.054
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.053
ndufa4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 40.052
atp2a1lATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like0.051
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.049
gpiaglucose phosphate isomerase a0.043
pgam2phosphoglycerate mutase 2 (muscle)0.041
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.041
zgc:91930zgc:919300.040
tpi1btriosephosphate isomerase 1b0.039
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.036
tfectranscription factor EC0.035
idh2isocitrate dehydrogenase 2 (NADP+), mitochondrial0.034
zgc:92631zgc:926310.034
dlstdihydrolipoamide S-succinyltransferase0.032
zgc:152873zgc:1528730.031
eef2l2eukaryotic translation elongation factor 2, like 20.030
atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.030
pvalb1parvalbumin 10.030
pabpc4poly(A) binding protein, cytoplasmic 4 (inducible form)0.029
hccsholocytochrome c synthase0.029
socs3bsuppressor of cytokine signaling 3b0.029
terttelomerase reverse transcriptase0.028
pvalb4parvalbumin 40.028
aco2aconitase 2, mitochondrial0.028
pvalb2parvalbumin 20.026
mdh1bmalate dehydrogenase 1b, NAD (soluble)0.025
junjun proto-oncogene0.025
pvalb3parvalbumin 30.024
zgc:111961zgc:1119610.024
anxa11aannexin A11a0.023
zgc:63976zgc:639760.022
casq2calsequestrin 20.022
myl10myosin, light chain 10, regulatory0.022
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.021
tmem38atransmembrane protein 38A0.020
zgc:64133zgc:641330.020
LOC5609446-phosphofructokinase type C-like0.020
ldb3aLIM-domain binding factor 3a0.019
slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.018
pdha1apyruvate dehydrogenase (lipoamide) alpha 1a0.018
hspa9heat shock protein 90.018
mibp2muscle-specific beta 1 integrin binding protein 20.018
pdhxpyruvate dehydrogenase complex, component X0.018
ogdhoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)0.017
tomm34translocase of outer mitochondrial membrane 340.017
mybpc2bmyosin binding protein C, fast type b0.017
impdh1binosine 5'-phosphate dehydrogenase 1b0.016
tyrp1btyrosinase-related protein 1b0.016
cox6a1cytochrome c oxidase subunit VIa polypeptide 10.016
mycl1bv-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b0.016
myl1myosin, light chain 1, alkali; skeletal, fast0.015
rlbp1bretinaldehyde binding protein 1b0.015
lhcgrluteinizing hormone/choriogonadotropin receptor0.015
LOC555482tachykinin receptor 3-like0.015
marsmethionine-tRNA synthetase0.014
zgc:100919zgc:1009190.014
pygmbphosphorylase, glycogen (muscle) b0.014
fxr2fragile X mental retardation, autosomal homolog 20.014
prdx4peroxiredoxin 40.014
cox8acytochrome c oxidase subunit 8a0.014
ucp3uncoupling protein 30.014
vdac2voltage-dependent anion channel 20.014
socs3asuppressor of cytokine signaling 3a0.014
pgpphosphoglycolate phosphatase0.013
metap1methionyl aminopeptidase 10.013
tkttransketolase0.013
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.013
keap1akelch-like ECH-associated protein 1a0.013
aox3aldehyde oxidase 30.013
rarsarginyl-tRNA synthetase0.013
ldhalactate dehydrogenase A40.013
slc25a25asolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a0.013
eef2kelongation factor-2 kinase0.013
zgc:162329zgc:1623290.013
pcsk5aproprotein convertase subtilisin/kexin type 5a0.013
ssbSjogren syndrome antigen B (autoantigen La)0.013
zfp36l1bzinc finger protein 36, C3H type-like 1b0.013
rpl3ribosomal protein L30.013
cav3caveolin 30.012
mylz3myosin, light polypeptide 3, skeletal muscle0.012
junbjun B proto-oncogene0.012
dhtkd1dehydrogenase E1 and transketolase domain containing 10.012
zgc:101724zgc:1017240.012
gclcglutamate-cysteine ligase, catalytic subunit0.012
mycamyelocytomatosis oncogene a0.012
hoxa9bhomeo box A9b0.012
srflserum response factor like0.012
byslbystin-like0.011
zgc:77235zgc:772350.011
atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.011
pgam1bphosphoglycerate mutase 1b0.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
atp-5Protein ATP-50.017
atp-2Protein ATP-20.016
ant-1.1Protein ANT-1.10.011
isp-1Protein ISP-10.011
F58F12.1Protein F58F12.10.011
cyc-2.1Protein CYC-2.10.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
blwbellwether0.102
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.050
ATPsyn-bATP synthase, subunit b0.047
CG10664CG10664 gene product from transcript CG10664-RB0.042
l(1)G0230lethal (1) G02300.039
GlyPGlycogen phosphorylase0.022
ATPsyn-gammaATP synthase-gamma chain0.022
Pglym78Phosphoglyceromutase0.015
CG11876CG11876 gene product from transcript CG11876-RA0.015
PgkPhosphoglycerate kinase0.015
Cyt-c-pCytochrome c proximal0.014
porinCG6647 gene product from transcript CG6647-RA0.014
EnoEnolase0.014
CG3321CG3321 gene product from transcript CG3321-RC0.013
ScsalphaSuccinyl coenzyme A synthetase alpha subunit0.013
CG7145CG7145 gene product from transcript CG7145-RD0.012
CG8709CG8709 gene product from transcript CG8709-RK0.011
trioCG18214 gene product from transcript CG18214-RA0.011
levyCG17280 gene product from transcript CG17280-RA0.011
CadNCadherin-N0.010
Spn27ASerpin 27A0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.597
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.369
TPI1triosephosphate isomerase 10.211
PHB2prohibitin 20.199
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.186
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.109
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.103
COX4I1cytochrome c oxidase subunit IV isoform 10.084
ATP5LATP synthase, H+ transporting, mitochondrial Fo complex, subunit G0.063
UQCRC1ubiquinol-cytochrome c reductase core protein I0.049
ENGendoglin0.045
CYC1cytochrome c-10.044
VDAC2voltage-dependent anion channel 20.042
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 50.040
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.034
NDUFB9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa0.031
ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d0.029
PGK1phosphoglycerate kinase 10.025
EIF4A1eukaryotic translation initiation factor 4A10.025
GPIglucose-6-phosphate isomerase0.024
ESRRGestrogen-related receptor gamma0.022
PPARGperoxisome proliferator-activated receptor gamma0.020
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.019
IMMTinner membrane protein, mitochondrial0.019
COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)0.017
FSTL1follistatin-like 10.017
QARSglutaminyl-tRNA synthetase0.017
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.016
ENO1enolase 1, (alpha)0.015
CHCHD2coiled-coil-helix-coiled-coil-helix domain containing 20.014
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.014
ATP5G1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)0.014
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.014
COX5Acytochrome c oxidase subunit Va0.013
EIF3Keukaryotic translation initiation factor 3, subunit K0.012
UQCRHubiquinol-cytochrome c reductase hinge protein0.011
UQCRQubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa0.011
MRPL37mitochondrial ribosomal protein L370.011
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.011
DBIdiazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)0.010
DDTD-dopachrome tautomerase0.010
KIFAP3kinesin-associated protein 30.010
CCDC90Bcoiled-coil domain containing 90B0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.540
Tpi1triosephosphate isomerase 10.309
Gpi1glucose phosphate isomerase 10.185
Pkm2pyruvate kinase, muscle0.140
Gm5506predicted gene 55060.083
Pgk1phosphoglycerate kinase 10.071
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.068
Aldoaaldolase A, fructose-bisphosphate0.062
Ldhalactate dehydrogenase A0.045
Pnp2purine-nucleoside phosphorylase 20.044
Trp53transformation related protein 530.028
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.025
Cscitrate synthase0.024
Aco2aconitase 2, mitochondrial0.021
Il6stinterleukin 6 signal transducer0.018
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.018
Pgam1phosphoglycerate mutase 10.017
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.016
Leprleptin receptor0.015
Ppargperoxisome proliferator activated receptor gamma0.014
Uqcrc1ubiquinol-cytochrome c reductase core protein 10.013
Pfklphosphofructokinase, liver, B-type0.011
Cyc1cytochrome c-10.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.412
Aldoaaldolase A, fructose-bisphosphate0.089
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.052
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.051
Mdh1malate dehydrogenase 1, NAD (soluble)0.051
Psma7proteasome (prosome, macropain) subunit, alpha type 70.042
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.035
Nhp2NHP2 ribonucleoprotein homolog (yeast)0.025
Mrps7mitochondrial ribosomal protein S70.024
Oaz1ornithine decarboxylase antizyme 10.024
Cox4i1cytochrome c oxidase subunit IV isoform 10.021
Ldhalactate dehydrogenase A0.014
Atp5g3ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)0.014
Fabp5fatty acid binding protein 5, epidermal0.012
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.011
Pgam1phosphoglycerate mutase 1 (brain)0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ATP4Atp4p1.000
ATP1Atp1p0.999
ATP5Atp5p0.985
ATP20Atp20p0.981
ATP18Atp18p0.969
ATP3Atp3p0.950
ATP2Atp2p0.948
ATP17Atp17p0.747
ATP16Atp16p0.741
ATP15Atp15p0.703
ATP14Atp14p0.448
ATP7Atp7p0.447
QCR2Qcr2p0.402
COX9Cox9p0.376
PET9Pet9p0.338
INH1Inh1p0.273
NDE1Nde1p0.212
QCR6Qcr6p0.179
MIR1Mir1p0.156
ATP6Atp6p0.147
LSC1Lsc1p0.126
TIM11Tim11p0.123
COX4Cox4p0.089
COX7Cox7p0.066
RPM2Rpm2p0.051
COX8Cox8p0.046
ATP8Atp8p0.045
HOR2Hor2p0.035
YPL247Chypothetical protein0.034
SRD1Srd1p0.032
PRY1Pry1p0.032
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.030
HEM15Hem15p0.029
YLR162Whypothetical protein0.027
YLR264C-Ahypothetical protein0.026
CUP1-1Cup1-1p0.026
YOL038C-Ahypothetical protein0.024
LEU2Leu2p0.023
YAR068Whypothetical protein0.023
ARP10Arp10p0.023
LEU5Leu5p0.022
YJR120Whypothetical protein0.022
UPS3Ups3p0.022
GYL1Gyl1p0.022
TPO4Tpo4p0.021
YDL241Whypothetical protein0.020
SPL2Spl2p0.020
AGC1Agc1p0.020
MER1Mer1p0.019
CAM1Cam1p0.019
ALD4Ald4p0.019
HXT7Hxt7p0.019
ZPS1Zps1p0.018
YLR042Chypothetical protein0.018
HXT3Hxt3p0.018
AUA1Aua1p0.017
KNH1Knh1p0.017
CPD1Cpd1p0.017
YPR157Whypothetical protein0.017
YAR066Whypothetical protein0.016
YBR013Chypothetical protein0.016
YCL057C-Ahypothetical protein0.016
YPL014Whypothetical protein0.015
GDH1Gdh1p0.014
ARG8Arg8p0.014
COX6Cox6p0.014
ICS2Ics2p0.014
FMT1Fmt1p0.014
HPF1Hpf1p0.013
MF(ALPHA)2Mf(alpha)2p0.013
YOL014Whypothetical protein0.013
HAP4Hap4p0.013
YOL013W-Ahypothetical protein0.013
PIR1Pir1p0.012
COX2Cox2p0.012
YML003Whypothetical protein0.012
CWP1Cwp1p0.012
BSC1Bsc1p0.012
SNO3Sno3p0.012
OPT2Opt2p0.012
IZH4Izh4p0.012
MDH1Mdh1p0.012
YPL067Chypothetical protein0.012
YIR035Chypothetical protein0.012
YPR096Chypothetical protein0.012
YLR040Chypothetical protein0.011
BI4Bi4p0.011
SCM4Scm4p0.011
MDM36Mdm36p0.011
DIC1Dic1p0.011
TIR3Tir3p0.011
PLB1Plb1p0.011
YJL107Chypothetical protein0.010
RRN5Rrn5p0.010
RNP1Rnp1p0.010
YGL006W-Ahypothetical protein0.010
YAL064Whypothetical protein0.010
NRG2Nrg2p0.010
ENO2Eno2p0.010