The network for 'embryonic digestive tract morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic digestive tract morphogenesis

The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.

NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.993
hnf1baHNF1 homeobox Ba0.937
pax2apaired box gene 2a0.932
fgf8afibroblast growth factor 8 a0.927
shhasonic hedgehog a0.755
aldh1a2aldehyde dehydrogenase 1 family, member A20.568
ptch1patched 10.542
ptch2patched 20.526
mibmind bomb0.496
gata5GATA-binding protein 50.473
tp53tumor protein p530.434
wnt5bwingless-type MMTV integration site family, member 5b0.388
col8a1acollagen, type VIII, alpha 1a0.383
dlx2adistal-less homeobox gene 2a0.298
smosmoothened homolog (Drosophila)0.290
ndr2nodal-related 20.285
osr2odd-skipped related 2 (Drosophila)0.255
snai1bsnail homolog 1b (Drosophila)0.242
tll1tolloid-like 10.235
rfx2regulatory factor X, 2 (influences HLA class II expression)0.224
sim1asingle-minded homolog 1a (Drosophila)0.213
bmp2bbone morphogenetic protein 2b0.207
ihhaIndian hedgehog homolog a0.196
notch1anotch homolog 1a0.189
gata6GATA-binding protein 60.187
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.186
vangl2vang-like 2 (van gogh, Drosophila)0.182
bmp4bone morphogenetic protein 40.164
nkx2.2aNK2 transcription factor related 2a0.161
wnt2bbwingless-type MMTV integration site family, member 2Bb0.148
jag1bjagged 1b0.136
fgf3fibroblast growth factor 30.133
hhexhematopoietically expressed homeobox0.133
ahctf1AT hook containing transcription factor 10.131
lmo4aLIM domain only 4a0.131
hnf4ahepatocyte nuclear factor 4, alpha0.128
wnt1wingless-type MMTV integration site family, member 10.121
hand2heart and neural crest derivatives expressed transcript 20.120
sfrp5secreted frizzled-related protein 50.119
plcg1phospholipase C, gamma 10.119
wnt8bwingless-type MMTV integration site family, member 8b0.119
col11a2collagen type XI alpha-20.112
efnb1ephrin B10.110
foxa2forkhead box A20.109
tbx16T-box gene 160.109
dlx4adistal-less homeobox gene 4a0.108
znfl2azinc finger-like gene 2a0.107
fzd8afrizzled homolog 8a0.106
rbpms2RNA binding protein with multiple splicing 20.105
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.102
dlx4bdistal-less homeobox gene 4b0.099
lhx1aLIM homeobox 1a0.098
wnt2bawingless-type MMTV integration site family, member 2Ba0.098
gpc4glypican 40.096
sox17SRY-box containing gene 170.095
foxj1aforkhead box J1a0.091
fli1afriend leukemia integration 1a0.090
pkd2polycystic kidney disease 20.088
bocbrother of CDO0.087
has3hyaluronan synthase 30.086
pax8paired box gene 80.085
cse1lchromosome segregation 1-like (S. cerevisiae)0.083
cdh2cadherin 2, neuronal0.082
rpa1replication protein A10.082
orgoogenesis-related gene0.080
tbx24T-box 240.079
pitx2paired-like homeodomain transcription factor 20.079
prp19PRP19/PSO4 homolog (S. cerevisiae)0.078
tfap2atranscription factor AP-2 alpha0.077
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.076
sema3aasemaphorin 3aa0.075
hmx4H6 family homeobox 40.073
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.071
sox32SRY-box containing gene 320.071
sox2SRY-box containing gene 20.069
grem2gremlin 2, cysteine knot superfamily0.069
cdx4caudal type homeo box transcription factor 40.068
dnmt7DNA (cytosine-5-)-methyltransferase 70.068
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.067
pth2parathyroid hormone 20.065
ventventral expressed homeobox0.064
sox10SRY-box containing gene 100.064
apex1APEX nuclease (multifunctional DNA repair enzyme) 10.063
dbx1adeveloping brain homeobox 1a0.063
dlx3bdistal-less homeobox gene 3b0.063
nkx2.5NK2 transcription factor related 50.063
notch3notch homolog 30.061
arnt2aryl hydrocarbon receptor nuclear translocator 20.060
ascl1aachaete-scute complex-like 1a (Drosophila)0.060
foxa1forkhead box A10.059
hoxa2bhomeo box A2b0.056
pou5f1POU domain, class 5, transcription factor 10.056
dlx5adistal-less homeobox gene 5a0.056
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
cicubitus interruptus0.954
Rho1CG8416 gene product from transcript CG8416-RB0.527
aopanterior open0.268
Ras85DRas oncogene at 85D0.177
eyaeyes absent0.085
Akt1CG4006 gene product from transcript CG4006-RA0.065
frcfringe connection0.063
JraJun-related antigen0.062
Cdc42CG12530 gene product from transcript CG12530-RA0.050
S6kRPS6-p70-protein kinase0.047
Rac2CG8556 gene product from transcript CG8556-RA0.040
Rac1CG2248 gene product from transcript CG2248-RA0.038
CblCG7037 gene product from transcript CG7037-RB0.034
Tsc1CG6147 gene product from transcript CG6147-RA0.032
ik2IkappaB kinase-like 20.023
HLH54FCG5005 gene product from transcript CG5005-RA0.020
Mekk1CG7717 gene product from transcript CG7717-RB0.015
Kap-alpha3karyopherin alpha30.014
Rab5Rab-protein 50.012
cpbcapping protein beta0.011
EgfrEpidermal growth factor receptor0.011
maskmultiple ankyrin repeats single KH domain0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SIN3ASIN3 homolog A, transcription regulator (yeast)0.995
RBBP4retinoblastoma binding protein 40.986
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.971
RBBP7retinoblastoma binding protein 70.955
HDAC1histone deacetylase 10.911
JUNjun proto-oncogene0.870
NR2E3nuclear receptor subfamily 2, group E, member 30.834
MAP2K4mitogen-activated protein kinase kinase 40.831
FGF10fibroblast growth factor 100.576
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.566
FGF1fibroblast growth factor 1 (acidic)0.547
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.467
PKP4plakophilin 40.354
RBL2retinoblastoma-like 2 (p130)0.347
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.341
ARRB1arrestin, beta 10.316
APCadenomatous polyposis coli0.297
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.279
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.254
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.171
SKIv-ski sarcoma viral oncogene homolog (avian)0.166
FGF7fibroblast growth factor 70.165
MTA2metastasis associated 1 family, member 20.156
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.154
RBL1retinoblastoma-like 1 (p107)0.151
CDK9cyclin-dependent kinase 90.139
CREBBPCREB binding protein0.124
HIC1hypermethylated in cancer 10.118
CBX1chromobox homolog 10.117
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.101
CBX5chromobox homolog 50.098
TRIP6thyroid hormone receptor interactor 60.094
PSEN1presenilin 10.091
YY1YY1 transcription factor0.091
TRRAPtransformation/transcription domain-associated protein0.089
FGFR1fibroblast growth factor receptor 10.087
MAPK8mitogen-activated protein kinase 80.086
SUZ12suppressor of zeste 12 homolog (Drosophila)0.084
STAG2stromal antigen 20.084
MAP3K1mitogen-activated protein kinase kinase kinase 10.078
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.076
RNF8ring finger protein 80.073
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.068
SIRT1sirtuin 10.060
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.060
GATAD2BGATA zinc finger domain containing 2B0.059
XPO7exportin 70.056
NCOR1nuclear receptor corepressor 10.056
TNIKTRAF2 and NCK interacting kinase0.056
ARRB2arrestin, beta 20.056
ESR1estrogen receptor 10.052
HDAC3histone deacetylase 30.051
RB1retinoblastoma 10.050
MYBBP1AMYB binding protein (P160) 1a0.049
NCF2neutrophil cytosolic factor 20.048
FOXF2forkhead box F20.048
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.046
MAP3K5mitogen-activated protein kinase kinase kinase 50.046
SAP30Sin3A-associated protein, 30kDa0.043
FOXF1forkhead box F10.043
SUFUsuppressor of fused homolog (Drosophila)0.040
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.040
FOXC1forkhead box C10.039
TCF4transcription factor 40.037
PDGFCplatelet derived growth factor C0.037
CHD4chromodomain helicase DNA binding protein 40.037
JUPjunction plakoglobin0.036
MBD3methyl-CpG binding domain protein 30.036
TBL3transducin (beta)-like 30.036
PPP1R16Aprotein phosphatase 1, regulatory (inhibitor) subunit 16A0.035
TP53BP2tumor protein p53 binding protein, 20.035
GLIS2GLIS family zinc finger 20.035
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein)0.035
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.034
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.034
MTA3metastasis associated 1 family, member 30.034
PDGFAplatelet-derived growth factor alpha polypeptide0.033
MAPK14mitogen-activated protein kinase 140.032
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.032
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.031
RUNX3runt-related transcription factor 30.030
CDK2AP1cyclin-dependent kinase 2 associated protein 10.030
GLI1GLI family zinc finger 10.029
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.029
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.029
TJP2tight junction protein 2 (zona occludens 2)0.028
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.027
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.027
DNMT1DNA (cytosine-5-)-methyltransferase 10.026
STK36serine/threonine kinase 360.025
MTA1metastasis associated 10.025
XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble0.024
KLF13Kruppel-like factor 130.023
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.023
MMP16matrix metallopeptidase 16 (membrane-inserted)0.023
TBX2T-box 20.022
COTL1coactosin-like 1 (Dictyostelium)0.022
APLP1amyloid beta (A4) precursor-like protein 10.022
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.998
Fgfr2fibroblast growth factor receptor 20.991
Gli3GLI-Kruppel family member GLI30.973
Fgf10fibroblast growth factor 100.971
Sox2SRY-box containing gene 20.967
Pax3paired box gene 30.933
Ctnnb1catenin (cadherin associated protein), beta 10.923
Lef1lymphoid enhancer binding factor 10.832
Hes1hairy and enhancer of split 1 (Drosophila)0.804
Meox2mesenchyme homeobox 20.791
Fgfr3fibroblast growth factor receptor 30.785
Bmp4bone morphogenetic protein 40.706
Sox9SRY-box containing gene 90.694
Gli2GLI-Kruppel family member GLI20.657
Tbx3T-box 30.656
Prrx1paired related homeobox 10.647
Fgf8fibroblast growth factor 80.611
Smad6MAD homolog 6 (Drosophila)0.588
Sall4sal-like 4 (Drosophila)0.477
Pitx2paired-like homeodomain transcription factor 20.436
Eya1eyes absent 1 homolog (Drosophila)0.426
Fgf9fibroblast growth factor 90.379
Pitx1paired-like homeodomain transcription factor 10.360
Ror2receptor tyrosine kinase-like orphan receptor 20.356
Tbx2T-box 20.351
Gata6GATA binding protein 60.327
Ptenphosphatase and tensin homolog0.297
Zeb1zinc finger E-box binding homeobox 10.291
Sox7SRY-box containing gene 70.274
Otx2orthodenticle homolog 2 (Drosophila)0.270
Hand1heart and neural crest derivatives expressed transcript 10.262
Pax2paired box gene 20.246
Twist2twist homolog 2 (Drosophila)0.241
Hoxd13homeobox D130.241
Alx4aristaless-like homeobox 40.226
Foxc1forkhead box C10.218
Hhexhematopoietically expressed homeobox0.207
Ikzf1IKAROS family zinc finger 10.204
Trp53transformation related protein 530.187
Pax6paired box gene 60.183
Insm1insulinoma-associated 10.183
Hoxa13homeobox A130.177
Fgf3fibroblast growth factor 30.177
Smad4MAD homolog 4 (Drosophila)0.175
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.174
Kdrkinase insert domain protein receptor0.172
Ezh2enhancer of zeste homolog 2 (Drosophila)0.168
Gscgoosecoid homeobox0.165
Tcf21transcription factor 210.164
Shesrc homology 2 domain-containing transforming protein E0.160
Hic1hypermethylated in cancer 10.150
Wnt5awingless-related MMTV integration site 5A0.148
Foxc2forkhead box C20.145
Nkx2-1NK2 homeobox 10.142
Ascl1achaete-scute complex homolog 1 (Drosophila)0.141
Gata4GATA binding protein 40.139
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.136
Efnb2ephrin B20.133
Rargretinoic acid receptor, gamma0.131
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.130
Fgfr1fibroblast growth factor receptor 10.129
Nf1neurofibromatosis 10.128
Hdac2histone deacetylase 20.109
Ptch1patched homolog 10.107
Wnt3awingless-related MMTV integration site 3A0.106
Chd7chromodomain helicase DNA binding protein 70.105
Msx1homeobox, msh-like 10.103
Edn3endothelin 30.099
Pkdccprotein kinase domain containing, cytoplasmic0.098
Tgfb2transforming growth factor, beta 20.097
Vegfavascular endothelial growth factor A0.096
Epha1Eph receptor A10.091
Tal1T-cell acute lymphocytic leukemia 10.091
Tcf3transcription factor 30.089
Gdnfglial cell line derived neurotrophic factor0.089
Six2sine oculis-related homeobox 2 homolog (Drosophila)0.088
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.087
Pou3f3POU domain, class 3, transcription factor 30.086
Hdac1histone deacetylase 10.084
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.082
Msx2homeobox, msh-like 20.081
Hoxa2homeobox A20.079
Sox11SRY-box containing gene 110.077
Hand2heart and neural crest derivatives expressed transcript 20.076
Vangl2vang-like 2 (van gogh, Drosophila)0.075
Hspg2perlecan (heparan sulfate proteoglycan 2)0.072
Trp63transformation related protein 630.071
Pthlhparathyroid hormone-like peptide0.070
Gas1growth arrest specific 10.069
Tcfap2atranscription factor AP-2, alpha0.069
Hoxa1homeobox A10.069
Gbx2gastrulation brain homeobox 20.068
Ren1renin 1 structural0.066
Rarbretinoic acid receptor, beta0.064
Hmx1H6 homeobox 10.064
Robo3roundabout homolog 3 (Drosophila)0.063
JunJun oncogene0.063
Emx1empty spiracles homolog 1 (Drosophila)0.061
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism