The network for 'radial glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

radial glial cell differentiation

The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.

NameDescriptionProbabilityFunc Analog Organism
fzd8afrizzled homolog 8a0.973
notch3notch homolog 30.968
dladeltaA0.725
her6hairy-related 60.720
fzd7afrizzled homolog 7a0.642
axin2axin 2 (conductin, axil)0.617
fzd7bfrizzled homolog 7b0.614
sox2SRY-box containing gene 20.554
her15.1hairy and enhancer of split-related 15.10.537
sfrp1asecreted frizzled-related protein 1a0.533
her12hairy-related 120.476
pea3ETS-domain transcription factor pea30.473
notch1anotch homolog 1a0.444
dlcdeltaC0.430
eya1eyes absent homolog 10.420
cxcr4achemokine (C-X-C motif) receptor 4a0.382
cdh2cadherin 2, neuronal0.288
hey1hairy/enhancer-of-split related with YRPW motif 10.275
foxc1aforkhead box C1a0.213
dlddeltaD0.199
notch2notch homolog 20.192
ascl1bachaete-scute complex-like 1b (Drosophila)0.189
fgf3fibroblast growth factor 30.187
lmo4aLIM domain only 4a0.173
jag1bjagged 1b0.172
gli2aGLI-Kruppel family member GLI2a0.165
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.163
stmstarmaker0.161
ephb4aeph receptor B4a0.158
dag1dystroglycan 10.151
sox3SRY-box containing gene 30.149
pak1p21/Cdc42/Rac1-activated kinase 10.147
ephb3aeph receptor B3a0.146
cxcr4bchemokine (C-X-C motif), receptor 4b0.135
msi1musashi homolog 1 (Drosophila)0.132
lmx1b.1LIM homeobox transcription factor 1, beta 10.131
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.126
klf4Kruppel-like factor 40.119
crabp2bcellular retinoic acid binding protein 2, b0.115
wif1wnt inhibitory factor 10.113
sesn1sestrin 10.111
ascl1aachaete-scute complex-like 1a (Drosophila)0.110
ephb4beph receptor B4b0.104
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.104
dlbdeltaB0.103
nrarpanotch-regulated ankyrin repeat protein a0.101
lamc1laminin, gamma 10.099
wlswntless homolog (Drosophila)0.097
scube2signal peptide, CUB domain, EGF-like 20.093
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.093
gyltl1bglycosyltransferase-like 1b0.090
tpbgltrophoblast glycoprotein-like0.089
six1bsine oculis homeobox homolog 1b0.086
tcf7transcription factor 7 (T-cell specific, HMG-box)0.085
neurog1neurogenin 10.085
six2asine oculis-related homeobox 2a0.084
wnt5bwingless-type MMTV integration site family, member 5b0.082
six4bsine oculis homeobox homolog 4b0.082
ptpraprotein tyrosine phosphatase, receptor type, A0.081
brd2abromodomain-containing 2a0.075
otx1borthodenticle homolog 1b0.071
fgfr1afibroblast growth factor receptor 1a0.069
rorbRAR-related orphan receptor B0.069
hsp47heat shock protein 470.068
nrarpbnotch-regulated ankyrin repeat protein b0.068
lft1lefty10.066
gro1groucho 10.064
fzd2frizzled homolog 20.064
bmp4bone morphogenetic protein 40.063
traf4atnf receptor-associated factor 4a0.063
her1hairy-related 10.061
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.058
twist2twist20.055
hesx1homeo box (expressed in ES cells) 10.053
fgf17fibroblast growth factor 170.050
twist1atwist1a0.049
hoxa13bhomeo box A13b0.048
jag2jagged 20.047
ccnd1cyclin D10.047
wnt11wingless-type MMTV integration site family, member 110.046
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.046
znf703zinc finger protein 7030.046
fezf2FEZ family zinc finger 20.046
eya2eyes absent homolog 2 (Drosophila)0.046
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.045
mmp2matrix metalloproteinase 20.045
tmpoathymopoietin a0.044
amotl2aangiomotin like 2a0.044
ptch1patched 10.044
gro2groucho 20.043
rxrgaretinoid x receptor, gamma a0.043
sox11aSRY-box containing gene 11a0.042
arnt2aryl hydrocarbon receptor nuclear translocator 20.042
tbx6T-box gene 60.042
mibmind bomb0.040
efnb3bephrin B3b0.040
hes6hairy and enhancer of split 6 (Drosophila)0.039
acvr1bactivin A receptor, type IB0.039
sulf1sulfatase 10.038
lama5laminin, alpha 50.037
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI31.000
Fgfr2fibroblast growth factor receptor 20.989
Shhsonic hedgehog0.989
Lef1lymphoid enhancer binding factor 10.964
Ctnnb1catenin (cadherin associated protein), beta 10.952
Fgfr1fibroblast growth factor receptor 10.911
Pax2paired box gene 20.868
Cdkn1bcyclin-dependent kinase inhibitor 1B0.782
Pax3paired box gene 30.755
Sox2SRY-box containing gene 20.732
Stat5bsignal transducer and activator of transcription 5B0.731
Pitx2paired-like homeodomain transcription factor 20.591
Gli2GLI-Kruppel family member GLI20.483
Foxc1forkhead box C10.450
Prrx1paired related homeobox 10.438
Nognoggin0.407
Otx2orthodenticle homolog 2 (Drosophila)0.385
Emx2empty spiracles homolog 2 (Drosophila)0.373
Foxg1forkhead box G10.346
Tbx3T-box 30.322
Fgfr3fibroblast growth factor receptor 30.317
Zeb1zinc finger E-box binding homeobox 10.302
Eya1eyes absent 1 homolog (Drosophila)0.300
Bmp4bone morphogenetic protein 40.291
Emx1empty spiracles homolog 1 (Drosophila)0.288
Arandrogen receptor0.274
Msx2homeobox, msh-like 20.274
Dlx5distal-less homeobox 50.269
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.267
Ror2receptor tyrosine kinase-like orphan receptor 20.267
Msx1homeobox, msh-like 10.266
Ptch1patched homolog 10.254
Chd7chromodomain helicase DNA binding protein 70.248
Sox9SRY-box containing gene 90.246
Fgf10fibroblast growth factor 100.216
Pax6paired box gene 60.211
Hes1hairy and enhancer of split 1 (Drosophila)0.208
Trp63transformation related protein 630.204
Irf9interferon regulatory factor 90.184
Smosmoothened homolog (Drosophila)0.173
Twist2twist homolog 2 (Drosophila)0.161
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.135
Lrp6low density lipoprotein receptor-related protein 60.130
Stat3signal transducer and activator of transcription 30.119
Stat5asignal transducer and activator of transcription 5A0.107
Leprleptin receptor0.101
Bmp7bone morphogenetic protein 70.090
Vangl2vang-like 2 (van gogh, Drosophila)0.090
Jag1jagged 10.077
Il6stinterleukin 6 signal transducer0.077
Runx2runt related transcription factor 20.069
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.060
Psen1presenilin 10.058
Otx1orthodenticle homolog 1 (Drosophila)0.057
Pbx1pre B-cell leukemia transcription factor 10.056
Rararetinoic acid receptor, alpha0.056
Tgfb2transforming growth factor, beta 20.055
Rarbretinoic acid receptor, beta0.054
Dll1delta-like 1 (Drosophila)0.053
Rargretinoic acid receptor, gamma0.052
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.052
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.049
Prrx2paired related homeobox 20.048
Gata3GATA binding protein 30.047
Rac1RAS-related C3 botulinum substrate 10.047
Gscgoosecoid homeobox0.046
Tbx15T-box 150.046
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.046
Fgf8fibroblast growth factor 80.044
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.041
Lmx1aLIM homeobox transcription factor 1 alpha0.041
Meox2mesenchyme homeobox 20.040
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.040
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.040
Tcf7transcription factor 7, T-cell specific0.039
Prlrprolactin receptor0.038
Ghrgrowth hormone receptor0.037
Fgf9fibroblast growth factor 90.035
Smad6MAD homolog 6 (Drosophila)0.032
Gas1growth arrest specific 10.032
Wnt5awingless-related MMTV integration site 5A0.032
Gbx2gastrulation brain homeobox 20.032
Retret proto-oncogene0.031
Foxp3forkhead box P30.030
Ptk7PTK7 protein tyrosine kinase 70.027
Apcadenomatosis polyposis coli0.025
En1engrailed 10.025
Sox11SRY-box containing gene 110.024
Bmp2bone morphogenetic protein 20.023
Pthlhparathyroid hormone-like peptide0.023
Hoxa1homeobox A10.023
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.023
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.022
Fzd1frizzled homolog 1 (Drosophila)0.022
Ptenphosphatase and tensin homolog0.022
JunJun oncogene0.022
Lepleptin0.021
Lhx1LIM homeobox protein 10.021
Hoxd11homeobox D110.021
Pax9paired box gene 90.021
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism