The network for 'regulation of muscle hypertrophy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of muscle hypertrophy

Any process that modulates the frequency, rate or extent of muscle hypertrophy.

NameDescriptionProbabilityFunc Analog Organism
hspb8heat shock protein, alpha-crystallin-related, b80.081
hspb9heat shock protein, alpha-crystallin-related, 90.080
hspb11heat shock protein, alpha-crystallin-related, b110.069
recql5RecQ protein-like 50.061
hspb1heat shock protein, alpha-crystallin-related, 10.043
igfbp1binsulin-like growth factor binding protein 1b0.043
arpc3actin related protein 2/3 complex, subunit 30.041
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.038
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.036
adrb2aadrenergic receptor, beta 2a0.035
arpc5bactin related protein 2/3 complex, subunit 5B0.033
vtg1vitellogenin 10.031
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.030
ctsl1acathepsin L, 1 a0.030
gpiaglucose phosphate isomerase a0.030
actn1actinin, alpha 10.030
slc30a2solute carrier family 30 (zinc transporter), member 20.029
cpa4carboxypeptidase A40.028
blmBloom syndrome0.028
dynlt3dynein, light chain, Tctex-type 30.027
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.026
ela2elastase 20.026
eif1axbeukaryotic translation initiation factor 1A, X-linked, b0.026
igfbp1ainsulin-like growth factor binding protein 1a0.025
hspb6heat shock protein, alpha-crystallin-related, b60.025
copebcore promoter element binding protein0.024
hspb2heat shock protein, alpha-crystallin-related, b20.024
cryaacrystallin, alpha A0.024
diaph2diaphanous homolog 2 (Drosophila)0.023
cdc42cell division cycle 420.022
c1ql4lcomplement component 1, q subcomponent-like 4 like0.022
hspb12heat shock protein, alpha-crystallin-related, b120.021
mt2metallothionein 20.020
slc6a4asolute carrier family 6 (neurotransmitter transporter, serotonin), member 4A0.020
hsp70heat shock cognate 70-kd protein0.019
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.019
tdhL-threonine dehydrogenase0.019
m17IL-6 subfamily cytokine M170.018
iqgap1IQ motif containing GTPase activating protein 10.018
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.018
igfbp3insulin-like growth factor binding protein 30.017
krt18keratin 180.017
tomm40translocase of outer mitochondrial membrane 40 homolog (yeast)0.016
LOC100149148novel protein similar to myosin heavy chain 4 (myhc4)0.016
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.016
fasFas (TNF receptor superfamily, member 6)0.016
arpc4lactin related protein 2/3 complex, subunit 4, like0.016
casq2calsequestrin 20.016
hspb7heat shock protein family, alpha-crystallin-related, b70.015
myhz2myosin, heavy polypeptide 2, fast muscle specific0.015
syt11asynaptotagmin XIa0.015
nap1l4anucleosome assembly protein 1-like 4a0.015
smyhc1slow myosin heavy chain 10.015
lgals2alectin, galactoside-binding, soluble, 2a0.015
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.015
crybb1crystallin, beta B10.014
tmietransmembrane inner ear0.014
ndufa4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 40.014
slc6a5solute carrier family 6 (neurotransmitter transporter, glycine), member 50.014
LOC798872deiodinase 30.014
ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.013
gstt1bglutathione S-transferase theta 1b0.013
hdlbphigh density lipoprotein-binding protein (vigilin)0.013
ddtD-dopachrome tautomerase0.013
aldoaaaldolase a, fructose-bisphosphate, a0.013
twf1atwinfilin, actin-binding protein, homolog 1a0.013
LOC100000862UPF0466 protein C22orf32 homolog, mitochondrial-like0.013
naa50N(alpha)-acetyltransferase 50, NatE catalytic subunit0.013
psenenpresenilin enhancer 2 homolog0.013
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.013
gnb5bguanine nucleotide binding protein (G protein), beta 5b0.013
papss2b3'-phosphoadenosine 5'-phosphosulfate synthase 2b0.013
testestis derived transcript (3 LIM domains)0.012
nr2e3nuclear receptor subfamily 2, group E, member 30.012
baxabcl2-associated X protein, a0.012
LOC564872monocarboxylate transporter 7-like0.012
onecut1one cut domain, family member 10.012
sncgasynuclein, gamma a0.012
lifrbleukemia inhibitory factor receptor alpha b0.012
smyhc2slow myosin heavy chain 20.012
nrn1neuritin 10.012
anxa6annexin A60.012
il1binterleukin 1, beta and interleukin 1, beta0.012
prdx4peroxiredoxin 40.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.479
NCOA1nuclear receptor coactivator 10.323
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.293
ITGB1BP3integrin beta 1 binding protein 30.189
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.168
VPS29vacuolar protein sorting 29 homolog (S. cerevisiae)0.125
BMPR1Bbone morphogenetic protein receptor, type IB0.067
CRYABcrystallin, alpha B0.065
TRPC3transient receptor potential cation channel, subfamily C, member 30.057
C3orf15chromosome 3 open reading frame 150.053
ACTN1actinin, alpha 10.049
IGF2Rinsulin-like growth factor 2 receptor0.041
CALCAcalcitonin-related polypeptide alpha0.033
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.033
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.032
HSPB8heat shock 22kDa protein 80.029
DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 110.021
CIAPIN1cytokine induced apoptosis inhibitor 10.021
ATXN1ataxin 10.021
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.021
PKD2polycystic kidney disease 2 (autosomal dominant)0.020
BAG3BCL2-associated athanogene 30.020
DLG2discs, large homolog 2 (Drosophila)0.019
VASPvasodilator-stimulated phosphoprotein0.018
SF3B4splicing factor 3b, subunit 4, 49kDa0.017
CYLDcylindromatosis (turban tumor syndrome)0.015
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.015
MBNL1muscleblind-like (Drosophila)0.014
MTORmechanistic target of rapamycin (serine/threonine kinase)0.014
SF3B3splicing factor 3b, subunit 3, 130kDa0.013
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.013
GRIA4glutamate receptor, ionotrophic, AMPA 40.013
FAF1Fas (TNFRSF6) associated factor 10.012
ERBB2IPerbb2 interacting protein0.012
MAPK6mitogen-activated protein kinase 60.011
TMF1TATA element modulatory factor 10.011
PRKCQprotein kinase C, theta0.011
EFTUD2elongation factor Tu GTP binding domain containing 20.011
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.010
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.010
ITPR3inositol 1,4,5-trisphosphate receptor, type 30.010
NRIP1nuclear receptor interacting protein 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ednraendothelin receptor type A0.495
Bmp4bone morphogenetic protein 40.236
Ppargperoxisome proliferator activated receptor gamma0.190
Dmddystrophin, muscular dystrophy0.153
Gdf5growth differentiation factor 50.143
Esr1estrogen receptor 1 (alpha)0.132
Nos1nitric oxide synthase 1, neuronal0.122
Leprleptin receptor0.122
Ptprbprotein tyrosine phosphatase, receptor type, B0.083
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.083
Agtr1aangiotensin II receptor, type 1a0.080
Rock2Rho-associated coiled-coil containing protein kinase 20.078
Drd2dopamine receptor D20.076
Hivep2human immunodeficiency virus type I enhancer binding protein 20.075
Cav1caveolin 1, caveolae protein0.073
Vegfavascular endothelial growth factor A0.065
Ghrgrowth hormone receptor0.062
Vdrvitamin D receptor0.057
Plin1perilipin 10.057
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)0.055
Axin1axin 10.054
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.052
Vav3vav 3 oncogene0.050
Fgfr3fibroblast growth factor receptor 30.048
Timp1tissue inhibitor of metalloproteinase 10.047
Abcc9ATP-binding cassette, sub-family C (CFTR/MRP), member 90.044
Runx2runt related transcription factor 20.043
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.042
Apcadenomatosis polyposis coli0.042
Nos2nitric oxide synthase 2, inducible0.041
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.041
Map3k5mitogen-activated protein kinase kinase kinase 50.040
Ror2receptor tyrosine kinase-like orphan receptor 20.040
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.039
Ptrfpolymerase I and transcript release factor0.039
Mef2amyocyte enhancer factor 2A0.037
Ednrbendothelin receptor type B0.037
Adrb3adrenergic receptor, beta 30.037
Csf1colony stimulating factor 1 (macrophage)0.035
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.034
Adipoqadiponectin, C1Q and collagen domain containing0.032
Nos3nitric oxide synthase 3, endothelial cell0.032
Lama2laminin, alpha 20.031
Pnpla2patatin-like phospholipase domain containing 20.030
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.029
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.029
Gucy1b3guanylate cyclase 1, soluble, beta 30.028
Prrx1paired related homeobox 10.028
Il1r1interleukin 1 receptor, type I0.027
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.027
Smad3MAD homolog 3 (Drosophila)0.027
Siah2seven in absentia 20.027
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.026
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.026
Gsk3bglycogen synthase kinase 3 beta0.025
Lrp6low density lipoprotein receptor-related protein 60.024
Gdf6growth differentiation factor 60.024
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.024
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.024
Epas1endothelial PAS domain protein 10.024
Gdf1growth differentiation factor 10.024
Ptch1patched homolog 10.023
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.022
Ptgs2prostaglandin-endoperoxide synthase 20.022
Aprtadenine phosphoribosyl transferase0.022
Cideccell death-inducing DFFA-like effector c0.022
Snx13sorting nexin 130.021
Grxcr1glutaredoxin, cysteine rich 10.021
Apoeapolipoprotein E0.021
Mtap2microtubule-associated protein 20.020
Scn7asodium channel, voltage-gated, type VII, alpha0.020
Actr3ARP3 actin-related protein 3 homolog (yeast)0.020
Lrrk2leucine-rich repeat kinase 20.019
Pcsk6proprotein convertase subtilisin/kexin type 60.019
Cacna1hcalcium channel, voltage-dependent, T type, alpha 1H subunit0.019
Mkl2MKL/myocardin-like 20.019
Pdlim3PDZ and LIM domain 30.019
Lhfplipoma HMGIC fusion partner0.019
Ptprmprotein tyrosine phosphatase, receptor type, M0.019
Tgfbr2transforming growth factor, beta receptor II0.018
Bmp5bone morphogenetic protein 50.018
Cxcl12chemokine (C-X-C motif) ligand 120.018
Col14a1collagen, type XIV, alpha 10.018
Kcnk2potassium channel, subfamily K, member 20.017
Fkbp3FK506 binding protein 30.017
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.017
Lifleukemia inhibitory factor0.016
Ren1renin 1 structural0.016
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.016
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.016
Fam49bfamily with sequence similarity 49, member B0.016
Zswim6zinc finger, SWIM domain containing 60.016
Bicd2bicaudal D homolog 2 (Drosophila)0.016
Trim55tripartite motif-containing 550.016
Tomm20translocase of outer mitochondrial membrane 20 homolog (yeast)0.015
Nppbnatriuretic peptide type B0.015
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism