The network for 'blood coagulation fibrin clot formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blood coagulation fibrin clot formation

A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.

NameDescriptionProbabilityFunc Analog Organism
fggfibrinogen, gamma polypeptide0.768
fgbfibrinogen, B beta polypeptide0.660
c9complement component 90.445
fgafibrinogen alpha chain0.433
apomapolipoprotein M0.428
ambplalpha-1-microglobulin/bikunin precursor, like0.325
cfhl4complement factor H like 40.312
vtnbvitronectin b0.229
gipgastric inhibitory polypeptide0.229
cfbcomplement factor B0.137
LOC796447hypothetical protein LOC7964470.127
plod1aprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a0.104
ucp1uncoupling protein 10.086
antxr1anthrax toxin receptor 10.085
nr1h5nuclear receptor subfamily 1, group H, member 50.081
ces2carboxylesterase 2 (intestine, liver)0.073
bhmtbetaine-homocysteine methyltransferase0.071
hao1hydroxyacid oxidase (glycolate oxidase) 10.067
gpt2lglutamic pyruvate transaminase (alanine aminotransferase) 2, like0.066
apobapolipoprotein B0.063
ftcdformiminotransferase cyclodeaminase0.063
serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.041
shbgsex hormone binding globulin0.038
vaspvasodilator-stimulated phosphoprotein0.038
f5coagulation factor V0.037
arl4caADP-ribosylation factor-like 4Ca0.036
hapln1ahyaluronan and proteoglycan link protein 1a0.033
f7coagulation factor VII0.032
serpind1serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 10.030
aqp12aquaporin 120.027
mpxmyeloid-specific peroxidase0.026
fbn2bfibrillin 2b0.024
itih2inter-alpha (globulin) inhibitor H20.023
frem1aFras1 related extracellular matrix 1a0.023
fetubfetuin B0.023
pklrpyruvate kinase, liver and RBC0.023
apoc2apolipoprotein C-II0.022
lmnalamin A0.022
nav3neuron navigator 30.021
ghrbgrowth hormone receptor b0.021
fabp10afatty acid binding protein 10a, liver basic0.020
angpt1angiopoietin 10.020
apoa1apolipoprotein A-I0.019
rbp4retinol binding protein 4, plasma0.019
serpinc1serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 10.019
apoa4apolipoprotein A-IV0.018
wnt10awingless-type MMTV integration site family, member 10a0.018
masp2mannan-binding lectin serine peptidase 20.017
bfbcomplement component bfb0.017
hoxa11ahomeo box A11a0.017
itgb1b.2integrin, beta 1b.20.016
cdkl1cyclin-dependent kinase-like 1 (CDC2-related kinase)0.015
angpt2angiopoietin 20.014
smyd3SET and MYND domain containing 30.013
ghragrowth hormone receptor a0.013
mat1amethionine adenosyltransferase I, alpha0.013
tcf7transcription factor 7 (T-cell specific, HMG-box)0.012
procprotein C (inactivator of coagulation factors Va and VIIIa)0.012
LOC100149559complement C1q-like protein 4-like0.012
scdstearoyl-CoA desaturase (delta-9-desaturase)0.011
kng1kininogen 10.011
igfbp2ainsulin-like growth factor binding protein 2a0.011
insrbinsulin receptor b0.011
slit2slit (Drosophila) homolog 20.011
fesfeline sarcoma oncogene0.011
LOC567384interferon-induced protein with tetratricopeptide repeats 5-like0.010
myl7myosin, light polypeptide 7, regulatory0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cfhcomplement factor H0.041
Fggfibrinogen gamma chain0.039
Cfbcomplement factor B0.023
C1scomplement component 1, s subcomponent0.016
C1rcomplement component 1, r subcomponent0.015
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.015
C3complement component 30.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism