The network for 'proton transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proton transport

The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Danio rerio
NameDescriptionProbabilityFunc Analog Organism
atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.318
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.210
cox5abcytochrome c oxidase subunit Vab0.181
cox8acytochrome c oxidase subunit 8a0.171
ca15acarbonic anhydrase XV a0.070
pahphenylalanine hydroxylase0.063
osr2odd-skipped related 2 (Drosophila)0.062
actn2actinin, alpha 20.053
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.042
cox6a1cytochrome c oxidase subunit VIa polypeptide 10.041
slc4a4asolute carrier family 4, member 4a0.038
zgc:111961zgc:1119610.036
cx39.9connexin 39.90.034
atp6v1g1ATPase, H+ transporting, V1 subunit G isoform 10.034
slc4a1bsolute carrier family 4, anion exchanger, member 1b0.027
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.026
fgf20bfibroblast growth factor 20b0.026
zgc:73293zgc:732930.024
ndfip1Nedd4 family interacting protein 10.023
atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.022
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.022
pdzk1PDZ domain containing 10.021
cdh17cadherin 17, LI cadherin (liver-intestine)0.020
slc25a3asolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a0.018
atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.018
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.018
stra6stimulated by retinoic acid gene 6 homolog (mouse)0.017
cap2CAP, adenylate cyclase-associated protein, 2 (yeast)0.017
zgc:194876zgc:1948760.016
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.016
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.016
uqcrbubiquinol-cytochrome c reductase binding protein0.016
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.015
slc26a1solute carrier family 26 (sulfate transporter), member 10.015
alx4aaristaless-like homeobox 4a0.014
LOC100332034NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like0.014
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.011
aco2aconitase 2, mitochondrial0.011
gja3gap junction protein, alpha 30.011
slc4a2asolute carrier family 4, anion exchanger, member 2a0.011
chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.010
zgc:92631zgc:926310.010
slc13a1solute carrier family 13 (sodium/sulphate symporters), member 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Vha55Vacuolar H[+]-ATPase 55kD B subunit0.421
Vha26Vacuolar H[+]-ATPase 26kD E subunit0.119
VhaSFDVacuolar H[+]-ATPase SFD subunit0.074
a5antennal protein 50.068
l(1)G0230lethal (1) G02300.045
l(2)06225lethal (2) 062250.036
ATPsyn-gammaATP synthase-gamma chain0.028
CG10664CG10664 gene product from transcript CG10664-RB0.028
mttmangetout0.022
VhaPPA1-1CG7007 gene product from transcript CG7007-RA0.021
AGO2Argonaute 20.018
EfTuMElongation factor Tu mitochondrial0.018
Cyt-c-pCytochrome c proximal0.017
ATPsyn-bATP synthase, subunit b0.016
Hsc70-5Heat shock protein cognate 50.015
AconAconitase0.014
l(2)35Dilethal (2) 35Di0.012
slifslimfast0.012
Vps35Vacuolar protein sorting 350.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)0.838
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.785
COX5Bcytochrome c oxidase subunit Vb0.734
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.551
ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d0.517
COX6B1cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)0.352
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.341
COX7A2cytochrome c oxidase subunit VIIa polypeptide 2 (liver)0.265
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.213
COX8Acytochrome c oxidase subunit VIIIA (ubiquitous)0.198
COX4I1cytochrome c oxidase subunit IV isoform 10.181
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.180
COX2cytochrome c oxidase subunit II0.164
ATP5G1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)0.162
COX1cytochrome c oxidase subunit I0.158
COX7Bcytochrome c oxidase subunit VIIb0.150
UQCRQubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa0.147
CYC1cytochrome c-10.112
SETD8SET domain containing (lysine methyltransferase) 80.106
COX5Acytochrome c oxidase subunit Va0.103
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.103
CHCHD2coiled-coil-helix-coiled-coil-helix domain containing 20.100
UQCRC1ubiquinol-cytochrome c reductase core protein I0.100
NDUFA4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa0.094
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.082
ATP5J2ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F20.079
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.073
NDUFB2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa0.072
ATP6V1DATPase, H+ transporting, lysosomal 34kDa, V1 subunit D0.066
UQCR10ubiquinol-cytochrome c reductase, complex III subunit X0.062
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.061
PARK7Parkinson disease (autosomal recessive, early onset) 70.051
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.051
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E10.048
TBC1D10ATBC1 domain family, member 10A0.045
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.041
NDUFB9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa0.038
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.036
ND2MTND20.036
NDUFC2NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa0.033
EPB42erythrocyte membrane protein band 4.20.033
PRDX2peroxiredoxin 20.033
NDUFB1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa0.029
SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 10.029
ATP5EATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit0.027
MRPS15mitochondrial ribosomal protein S150.027
CA4carbonic anhydrase IV0.027
ANXA7annexin A70.024
NDUFA3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa0.023
ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a10.023
YBX1Y box binding protein 10.023
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.022
CLN3ceroid-lipofuscinosis, neuronal 30.021
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.021
EZRezrin0.020
GRPEL1GrpE-like 1, mitochondrial (E. coli)0.020
SOD1superoxide dismutase 1, soluble0.019
UQCRHubiquinol-cytochrome c reductase hinge protein0.018
NDUFA7NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa0.018
CHP2calcineurin B homologous protein 20.017
UBE4Aubiquitination factor E4A (UFD2 homolog, yeast)0.017
ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A0.017
CCDC56coiled-coil domain containing 560.016
COX6Ccytochrome c oxidase subunit VIc0.015
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.015
EIF3Ieukaryotic translation initiation factor 3, subunit I0.014
PSAPprosaposin0.014
PLEKHB2pleckstrin homology domain containing, family B (evectins) member 20.013
PDZK1PDZ domain containing 10.013
DDTD-dopachrome tautomerase0.013
RAI1retinoic acid induced 10.012
ODC1ornithine decarboxylase 10.012
NDUFC1NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa0.012
ATP6ATP synthase F0 subunit 60.012
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.012
SIGMAR1sigma non-opioid intracellular receptor 10.012
C2orf18chromosome 2 open reading frame 180.012
ANXA9annexin A90.011
NAGKN-acetylglucosamine kinase0.011
NDUFA6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa0.011
COX6A1cytochrome c oxidase subunit VIa polypeptide 10.011
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc34a1solute carrier family 34 (sodium phosphate), member 10.860
Neurod1neurogenic differentiation 10.791
Kiss1KiSS-1 metastasis-suppressor0.599
Spna1spectrin alpha 10.401
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.345
Pax6paired box gene 60.329
Ascl1achaete-scute complex homolog 1 (Drosophila)0.311
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.305
Cox5bcytochrome c oxidase, subunit Vb0.304
Aco2aconitase 2, mitochondrial0.246
Ptf1apancreas specific transcription factor, 1a0.223
Hbb-b1hemoglobin, beta adult major chain0.218
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.213
Hand2heart and neural crest derivatives expressed transcript 20.207
Neurod4neurogenic differentiation 40.187
Msx1homeobox, msh-like 10.184
Umoduromodulin0.183
Ank1ankyrin 1, erythroid0.167
Hand1heart and neural crest derivatives expressed transcript 10.151
Atp6v1b2ATPase, H+ transporting, lysosomal V1 subunit B20.143
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.142
Nhlh1nescient helix loop helix 10.134
Dlx6distal-less homeobox 60.131
Neurog2neurogenin 20.118
Cyc1cytochrome c-10.113
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.113
Atp6v0bATPase, H+ transporting, lysosomal V0 subunit B0.112
Gscgoosecoid homeobox0.110
Vamp2vesicle-associated membrane protein 20.102
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.099
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.096
Atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.092
Pax9paired box gene 90.087
Slc17a1solute carrier family 17 (sodium phosphate), member 10.086
Uqcrc1ubiquinol-cytochrome c reductase core protein 10.085
Evx1even skipped homeotic gene 1 homolog0.084
Atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.083
Tbx1T-box 10.075
Isl1ISL1 transcription factor, LIM/homeodomain0.075
Otx2orthodenticle homolog 2 (Drosophila)0.072
Kcnk3potassium channel, subfamily K, member 30.071
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.071
Clstn1calsyntenin 10.069
Neurog3neurogenin 30.068
Foxi1forkhead box I10.067
Prrx1paired related homeobox 10.065
Mab21l2mab-21-like 2 (C. elegans)0.065
Cideccell death-inducing DFFA-like effector c0.064
Prph2peripherin 20.064
MecomMDS1 and EVI1 complex locus0.061
Cftrcystic fibrosis transmembrane conductance regulator homolog0.060
BspryB-box and SPRY domain containing0.059
Pdzd3PDZ domain containing 30.059
Slc4a1solute carrier family 4 (anion exchanger), member 10.059
BC031181cDNA sequence BC0311810.056
Slc32a1solute carrier family 32 (GABA vesicular transporter), member 10.056
Rspo2R-spondin 2 homolog (Xenopus laevis)0.056
Sim2single-minded homolog 2 (Drosophila)0.055
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.055
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.054
Phb2prohibitin 20.054
Prrx2paired related homeobox 20.053
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.053
Fgf8fibroblast growth factor 80.052
Cckbrcholecystokinin B receptor0.052
Pdx1pancreatic and duodenal homeobox 10.052
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.052
Eporerythropoietin receptor0.051
Smosmoothened homolog (Drosophila)0.048
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.047
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.046
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.046
Crygacrystallin, gamma A0.045
Prox1prospero-related homeobox 10.044
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.044
Ostaorganic solute transporter alpha0.043
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.043
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.043
Hbb-b2hemoglobin, beta adult minor chain0.042
Etv2ets variant gene 20.042
Fgf4fibroblast growth factor 40.042
Asb9ankyrin repeat and SOCS box-containing 90.042
Gata1GATA binding protein 10.042
Tcfap2atranscription factor AP-2, alpha0.041
Atp6v1hATPase, H+ transporting, lysosomal V1 subunit H0.041
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.039
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.039
Dlx2distal-less homeobox 20.039
Lmx1bLIM homeobox transcription factor 1 beta0.039
Atp6v1e1ATPase, H+ transporting, lysosomal V1 subunit E10.039
Slc4a4solute carrier family 4 (anion exchanger), member 40.039
Klf1Kruppel-like factor 1 (erythroid)0.038
Slc26a7solute carrier family 26, member 70.038
Exoc6exocyst complex component 60.038
Prr15proline rich 150.037
Cscitrate synthase0.037
Prphperipherin0.037
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.036
Scnn1gsodium channel, nonvoltage-gated 1 gamma0.035
Il9rinterleukin 9 receptor0.035
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ATP1Atp1p0.997
ATP4Atp4p0.995
ATP2Atp2p0.921
ATP5Atp5p0.872
ATP7Atp7p0.835
ENA5Ena5p0.785
ATP18Atp18p0.775
ATP20Atp20p0.740
PET9Pet9p0.634
VMA13Vma13p0.586
VMA1Vma1p0.541
ATP15Atp15p0.533
ENA2Ena2p0.520
ATP16Atp16p0.501
VMA5Vma5p0.492
ATP17Atp17p0.482
ATP3Atp3p0.464
ATP14Atp14p0.453
AFG3Afg3p0.300
NDE1Nde1p0.251
TIM11Tim11p0.171
ATP6Atp6p0.158
COX8Cox8p0.131
COX9Cox9p0.131
MDM38Mdm38p0.131
MIR1Mir1p0.098
INH1Inh1p0.095
IMD2Imd2p0.087
COX7Cox7p0.085
VMA4Vma4p0.080
SFB3Sfb3p0.078
USA1Usa1p0.071
COX4Cox4p0.068
TNA1Tna1p0.057
LCB2Lcb2p0.057
PEX2Pex2p0.055
MDM32Mdm32p0.049
YER064Chypothetical protein0.048
ENA1Ena1p0.047
SPF1Spf1p0.045
PDC5Pdc5p0.044
RPM2Rpm2p0.043
HOR2Hor2p0.042
PMA1Pma1p0.040
GDH3Gdh3p0.040
ARR3Arr3p0.040
YLR264C-Ahypothetical protein0.039
SRD1Srd1p0.038
ATP8Atp8p0.038
YNL217Whypothetical protein0.037
MLS1Mls1p0.037
ZPR1Zpr1p0.036
YHR033Whypothetical protein0.035
QCR6Qcr6p0.035
COX13Cox13p0.035
YLR162Whypothetical protein0.034
HXK2Hxk2p0.033
YCL057C-Ahypothetical protein0.033
KHA1Kha1p0.033
YJR120Whypothetical protein0.032
YOL038C-Ahypothetical protein0.032
YHR078Whypothetical protein0.032
GSC2Gsc2p0.032
COX2Cox2p0.031
ZPS1Zps1p0.031
ADH2Adh2p0.031
YJL107Chypothetical protein0.030
MER1Mer1p0.030
LEU2Leu2p0.030
UPS3Ups3p0.030
OPT2Opt2p0.029
HPF1Hpf1p0.029
KNH1Knh1p0.028
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.028
CUP1-1Cup1-1p0.028
ARP10Arp10p0.027
CWP1Cwp1p0.027
PDC6Pdc6p0.027
YOL014Whypothetical protein0.027
BI4Bi4p0.026
YAR068Whypothetical protein0.026
ICS2Ics2p0.026
NEO1Neo1p0.026
HXT3Hxt3p0.026
SGE1Sge1p0.026
SNG1Sng1p0.026
YEL073Chypothetical protein0.025
BSC2Bsc2p0.025
ARO10Aro10p0.025
YBR013Chypothetical protein0.025
CAM1Cam1p0.025
YDR387Chypothetical protein0.025
FMT1Fmt1p0.025
LRO1Lro1p0.024
MRH1Mrh1p0.024
ALY1Aly1p0.024
SIM1Sim1p0.024
AUA1Aua1p0.024
QCR2Qcr2p0.023
AIM13Aim13p0.023