The network for 'reproductive process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reproductive process

A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 30.888
shhasonic hedgehog a0.774
dusp6dual specificity phosphatase 60.723
piwil1piwi-like 1 (Drosophila)0.673
alcambactivated leukocyte cell adhesion molecule b0.673
sox9aSRY-box containing gene 9a0.645
foxa2forkhead box A20.617
gli1GLI-Kruppel family member 10.614
sox3SRY-box containing gene 30.596
fgfr1afibroblast growth factor receptor 1a0.592
jag2jagged 20.581
evx1even-skipped homeobox 10.568
pax8paired box gene 80.568
aurkbaurora kinase B0.563
pbx4pre-B-cell leukemia transcription factor 40.536
fn1fibronectin 10.535
vasavasa homolog0.533
her6hairy-related 60.519
nop58NOP58 ribonucleoprotein homolog (yeast)0.507
crabp2acellular retinoic acid binding protein 2, a0.505
aldh1a2aldehyde dehydrogenase 1 family, member A20.481
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.462
six1bsine oculis homeobox homolog 1b0.461
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.460
gro1groucho 10.449
eif3geukaryotic translation initiation factor 3, subunit G0.446
robo3roundabout homolog 30.421
snrpcsmall nuclear ribonucleoprotein polypeptide C0.416
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.412
smad1MAD homolog 1 (Drosophila)0.405
tll1tolloid-like 10.405
gdf6agrowth differentiation factor 6a0.405
mibmind bomb0.404
ntn1anetrin 1a0.403
fanclFanconi anemia, complementation group L0.386
ptgs1prostaglandin-endoperoxide synthase 10.359
ndr2nodal-related 20.353
cct7chaperonin containing TCP1, subunit 7 (eta)0.333
osr1odd-skipped related 1 (Drosophila)0.328
sox32SRY-box containing gene 320.326
sox2SRY-box containing gene 20.314
cyp19a1acytochrome P450, family 19, subfamily A, polypeptide 1a0.310
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.308
e2f5E2F transcription factor 50.306
myhz2myosin, heavy polypeptide 2, fast muscle specific0.302
otx1borthodenticle homolog 1b0.293
hhiphedgehog interacting protein0.289
tp53tumor protein p530.285
myf5myogenic factor 50.282
twist1atwist1a0.264
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.262
pea3ETS-domain transcription factor pea30.259
chdchordin0.259
ascl1aachaete-scute complex-like 1a (Drosophila)0.258
prox1prospero-related homeobox gene 10.248
hoxa13bhomeo box A13b0.246
rspo1R-spondin homolog (Xenopus laevis)0.237
wnt11rwingless-type MMTV integration site family, member 11, related0.236
prnprs3prion protein, related sequence 30.235
muskmuscle, skeletal, receptor tyrosine kinase0.233
tardbpTAR DNA binding protein0.228
zff9zinc finger protein 90.227
s1pr2sphingosine-1-phosphate receptor 20.224
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.220
pkd2polycystic kidney disease 20.218
twist3twist30.218
bucbucky ball0.218
spry4sprouty (Drosophila) homolog 40.218
gpr126G protein-coupled receptor 1260.217
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.214
tfap2atranscription factor AP-2 alpha0.213
eif3deukaryotic translation initiation factor 3, subunit D0.212
unc5bunc-5 homolog B (C. elegans)0.209
six4bsine oculis homeobox homolog 4b0.206
eif3ceukaryotic translation initiation factor 3, subunit C0.204
pobpartial optokinetic response b0.203
sox9bSRY-box containing gene 9b0.202
notch1anotch homolog 1a0.199
bmp15bone morphogenetic protein 150.199
wt1awilms tumor 1a0.198
eomesaeomesodermin homolog a0.198
cdc26cell division cycle 26 homolog0.196
bmp2abone morphogenetic protein 2a0.195
sart3squamous cell carcinoma antigen recognised by T cells 30.194
sfrp1asecreted frizzled-related protein 1a0.192
gpiaglucose phosphate isomerase a0.183
sec61al1Sec61 alpha like 10.182
sf3b5splicing factor 3b, subunit 50.180
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.179
dynlrb1dynein, light chain, roadblock-type 10.179
foxi1forkhead box I10.178
notch3notch homolog 30.176
axin2axin 2 (conductin, axil)0.175
setbSET translocation (myeloid leukemia-associated) B0.174
pax7apaired box gene 7a0.173
restRE1-silencing transcription factor0.173
bmp4bone morphogenetic protein 40.173
dharmadharma0.168
piwil2piwi-like 2 (Drosophila)0.166
trpv6transient receptor potential cation channel, subfamily V, member 60.164
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.999
CREBBPCREB binding protein0.988
ESR1estrogen receptor 10.988
SP1Sp1 transcription factor0.987
EGFRepidermal growth factor receptor0.983
TP53tumor protein p530.972
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.959
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.954
RB1retinoblastoma 10.950
U2AF1U2 small nuclear RNA auxiliary factor 10.949
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.930
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.906
CDK2cyclin-dependent kinase 20.902
HDAC1histone deacetylase 10.894
CAV1caveolin 1, caveolae protein, 22kDa0.856
SMAD4SMAD family member 40.855
BRCA2breast cancer 2, early onset0.847
PABPC1poly(A) binding protein, cytoplasmic 10.812
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.795
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.776
ATXN1ataxin 10.765
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.751
RNPS1RNA binding protein S1, serine-rich domain0.748
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.725
SRPK1SRSF protein kinase 10.711
RPA1replication protein A1, 70kDa0.709
PTPN1protein tyrosine phosphatase, non-receptor type 10.691
ATF2activating transcription factor 20.681
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.678
QKIquaking homolog, KH domain RNA binding (mouse)0.677
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.655
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.654
EP300E1A binding protein p3000.654
SMAD3SMAD family member 30.635
ARandrogen receptor0.632
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.612
EEDembryonic ectoderm development0.603
PTPN11protein tyrosine phosphatase, non-receptor type 110.595
SRPK2SRSF protein kinase 20.593
SRSF1serine/arginine-rich splicing factor 10.576
NCOR1nuclear receptor corepressor 10.576
DNMT1DNA (cytosine-5-)-methyltransferase 10.575
NCOR2nuclear receptor corepressor 20.570
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)0.564
FLNAfilamin A, alpha0.561
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.544
GSK3Bglycogen synthase kinase 3 beta0.529
MCM7minichromosome maintenance complex component 70.520
MAPTmicrotubule-associated protein tau0.504
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.500
SRSF2serine/arginine-rich splicing factor 20.476
PRPF3PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)0.475
TFDP1transcription factor Dp-10.472
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.470
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.458
SNRPA1small nuclear ribonucleoprotein polypeptide A'0.455
FN1fibronectin 10.452
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.452
MAPK14mitogen-activated protein kinase 140.451
CCNA2cyclin A20.440
CALM1calmodulin 1 (phosphorylase kinase, delta)0.430
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.427
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.424
EIF3Beukaryotic translation initiation factor 3, subunit B0.417
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.399
E2F1E2F transcription factor 10.393
MCM3minichromosome maintenance complex component 30.383
PRPF4PRP4 pre-mRNA processing factor 4 homolog (yeast)0.381
TCP1t-complex 10.364
CCT2chaperonin containing TCP1, subunit 2 (beta)0.350
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.344
WAPALwings apart-like homolog (Drosophila)0.342
RBM39RNA binding motif protein 390.339
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.337
CHERPcalcium homeostasis endoplasmic reticulum protein0.327
INSRinsulin receptor0.325
RARAretinoic acid receptor, alpha0.321
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.320
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.317
SNW1SNW domain containing 10.309
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.308
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.307
FGFR2fibroblast growth factor receptor 20.306
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.305
CCT7chaperonin containing TCP1, subunit 7 (eta)0.301
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.298
WDR5WD repeat domain 50.296
FGFR1fibroblast growth factor receptor 10.295
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.291
GTPBP4GTP binding protein 40.289
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.289
SNRPGsmall nuclear ribonucleoprotein polypeptide G0.282
CD63CD63 molecule0.280
SRRM1serine/arginine repetitive matrix 10.279
ACTBactin, beta0.278
SMC3structural maintenance of chromosomes 30.277
CCT8chaperonin containing TCP1, subunit 8 (theta)0.277
COPS8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)0.269
PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)0.268
LRRK2leucine-rich repeat kinase 20.268
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slco2a1solute carrier organic anion transporter family, member 2a10.839
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.810
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.758
Gjb3gap junction protein, beta 30.583
Eef2eukaryotic translation elongation factor 20.555
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.536
Il8rbinterleukin 8 receptor, beta0.520
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.509
Trhrthyrotropin releasing hormone receptor0.495
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.485
Hoxa2homeo box A20.482
Chrm1cholinergic receptor, muscarinic 10.470
Bmp6bone morphogenetic protein 60.468
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.463
Tshbthyroid stimulating hormone, beta0.463
Zic1Zic family member 1 (odd-paired homolog, Drosophila)0.460
Scnn1bsodium channel, nonvoltage-gated 1, beta0.459
Col10a1collagen, type X, alpha 10.458
Bcl2B-cell CLL/lymphoma 20.452
Adra2aadrenergic, alpha-2A-, receptor0.450
Ddr1discoidin domain receptor tyrosine kinase 10.448
Cpxm2carboxypeptidase X (M14 family), member 20.440
Prl3d1Prolactin family 3, subfamily d, member 10.439
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.437
LOC246267resection-induced TPI (rs11)0.436
Insrrinsulin receptor-related receptor0.431
Gcnt3glucosaminyl (N-acetyl) transferase 3, mucin type0.430
Grk4G protein-coupled receptor kinase 40.429
Edn1endothelin 10.424
Anxa4annexin A40.423
Ptgs2prostaglandin-endoperoxide synthase 20.420
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.419
Olr857olfactory receptor 8570.418
Ghsrgrowth hormone secretagogue receptor0.418
Bmp7bone morphogenetic protein 70.418
Cd80Cd80 molecule0.418
Smgbneonatal submandibular gland protein B0.413
Prdm2PR domain containing 2, with ZNF domain0.412
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.411
Lhbluteinizing hormone beta0.408
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.406
Zfp36zinc finger protein 360.406
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.405
Igfbp5insulin-like growth factor binding protein 50.404
Gja1gap junction protein, alpha 10.404
Gpx3glutathione peroxidase 30.401
Ednrbendothelin receptor type B0.400
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.399
Odf4outer dense fiber of sperm tails 40.398
Il12binterleukin 12B0.396
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.396
Il3interleukin 30.394
Prpg1proline-rich proteoglycan 10.391
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.390
Il1rninterleukin 1 receptor antagonist0.387
Itgb1integrin, beta 10.386
Fosl1fos-like antigen 10.385
Trhr2thyrotropin releasing hormone receptor 20.384
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.378
Igfbp6insulin-like growth factor binding protein 60.378
Neurod2neurogenic differentiation 20.376
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.375
Mc4rmelanocortin 4 receptor0.372
Kcnc2potassium voltage gated channel, Shaw-related subfamily, member 20.370
Pdpnpodoplanin0.366
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.365
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.365
Sgp158proline-rich glycoprotein (sgp158)0.365
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.361
Ttc36tetratricopeptide repeat domain 360.360
Slc22a7solute carrier family 22 (organic anion transporter), member 70.359
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.358
Accn2amiloride-sensitive cation channel 2, neuronal0.356
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.355
Defb1defensin beta 10.353
Myl9myosin, light chain 9, regulatory0.352
Twist2twist homolog 2 (Drosophila)0.350
Ppypancreatic polypeptide0.349
Tgfbr2transforming growth factor, beta receptor II0.349
Gastgastrin0.348
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.347
Pitx3paired-like homeodomain 30.344
Oxtroxytocin receptor0.343
Aqp9aquaporin 90.341
Plauplasminogen activator, urokinase0.339
Cand1cullin-associated and neddylation-dissociated 10.338
Foxd1forkhead box D10.338
Kcnk3potassium channel, subfamily K, member 30.336
Gucy2fguanylate cyclase 2F0.335
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.335
Duox2dual oxidase 20.335
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.334
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.333
Foxi2forkhead box I20.329
Anxa2annexin A20.329
Sprr1alsmall proline-rich protein 1A-like0.329
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.328
Psg29pregnancy-specific glycoprotein 290.328
Fbxo23F-box only protein 230.326
Alpialkaline phosphatase, intestinal0.325
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
STE4Ste4p0.981
FAR1Far1p0.978
CDC24Cdc24p0.973
AGA1Aga1p0.970
SST2Sst2p0.965
FUS2Fus2p0.955
SPA2Spa2p0.952
FUS3Fus3p0.920
AGA2Aga2p0.916
FUS1Fus1p0.909
HHT1Hht1p0.899
SPO21Spo21p0.893
BEM1Bem1p0.892
CLA4Cla4p0.886
FIG2Fig2p0.877
HSP82Hsp82p0.829
CSI1Csi1p0.825
STE18Ste18p0.807
STE5Ste5p0.801
BMH2Bmh2p0.799
KAR5Kar5p0.799
FIG1Fig1p0.784
SSK1Ssk1p0.773
GIP1Gip1p0.770
MFA1Mfa1p0.765
MYO5Myo5p0.756
KIN1Kin1p0.741
GLC7Glc7p0.740
SSK2Ssk2p0.722
STE2Ste2p0.709
SPS22Sps22p0.693
CCT3Cct3p0.677
DIT2Dit2p0.673
STE20Ste20p0.658
PCI8Pci8p0.633
VPS13Vps13p0.620
CCT8Cct8p0.599
STE7Ste7p0.592
SLT2Slt2p0.587
BOI1Boi1p0.586
CRZ1Crz1p0.582
STE3Ste3p0.574
YDJ1Ydj1p0.571
LSG1Lsg1p0.561
PBS2Pbs2p0.534
RAS2Ras2p0.528
MSN2Msn2p0.503
TCP1Tcp1p0.483
MYO2Myo2p0.475
STE11Ste11p0.463
OSW1Osw1p0.454
DIT1Dit1p0.449
ADY3Ady3p0.448
FAR3Far3p0.439
SPT15Spt15p0.436
RAD53Rad53p0.436
SAW1Saw1p0.428
FAR7Far7p0.416
MPC54Mpc54p0.415
CWP2Cwp2p0.412
RHO1Rho1p0.412
RRI1Rri1p0.410
MKK2Mkk2p0.402
CNB1Cnb1p0.397
RPD3Rpd3p0.396
CMD1Cmd1p0.389
CHS3Chs3p0.387
CRR1Crr1p0.378
OSW2Osw2p0.377
GSC2Gsc2p0.369
PTP2Ptp2p0.369
HHF2Hhf2p0.364
FKS3Fks3p0.363
MF(ALPHA)1Mf(alpha)1p0.354
GPA1Gpa1p0.352
RAD9Rad9p0.351
SPO71Spo71p0.351
SNF1Snf1p0.346
GIM3Gim3p0.344
SIR4Sir4p0.341
POL32Pol32p0.341
CCT5Cct5p0.340
SSA3Ssa3p0.340
TPK1Tpk1p0.340
RGS2Rgs2p0.335
ACT1Act1p0.329
NPL6Npl6p0.328
PKH2Pkh2p0.326
HSL1Hsl1p0.321
MATALPHA1Matalpha1p0.319
EXO1Exo1p0.317
DTR1Dtr1p0.316
GFA1Gfa1p0.316
SNC2Snc2p0.316
PDS1Pds1p0.312
SLK19Slk19p0.309
SPR3Spr3p0.309
SWI4Swi4p0.306
PRB1Prb1p0.303
SNF12Snf12p0.302