The network for 'larval heart development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

larval heart development

The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.

NameDescriptionProbabilityFunc Analog Organism
itgb1b.2integrin, beta 1b.20.940
nrp1bneuropilin 1b0.850
itgb1bintegrin, beta 1b0.845
nrp1aneuropilin 1a0.800
itgavintegrin, alpha V0.472
egr1early growth response 10.472
itgb1aintegrin, beta 1a0.448
itgb1b.1integrin, beta 1b.10.360
slit3slit (Drosophila) homolog 30.332
nrp2aneuropilin 2a0.320
ptger2aprostaglandin E receptor 2a (subtype EP2)0.201
sox9aSRY-box containing gene 9a0.193
antxr1anthrax toxin receptor 10.191
tfectranscription factor EC0.169
tgfb3transforming growth factor, beta 30.157
efnb2aephrin B2a0.143
igfbp6binsulin-like growth factor binding protein 6b0.123
nrp2bneuropilin 2b0.119
rargaretinoic acid receptor gamma a0.112
esrrgaestrogen-related receptor gamma a0.086
LOC100003330melanocortin-2 receptor accessory protein 2-like0.082
skianuclear oncoprotein skia0.080
igfbp6ainsulin-like growth factor binding protein 6a0.074
egr2bearly growth response 2b0.057
tcf4transcription factor 40.055
efna2ephrin A20.055
lpar1lysophosphatidic acid receptor 10.053
edn1endothelin 10.051
ldb2aLIM-domain binding factor 2a0.048
loxl3blysyl oxidase-like 3b0.044
prickle2prickle-like 2 (Drosophila)0.044
mef2dmyocyte enhancer factor 2d0.038
jam2bjunctional adhesion molecule 2b0.038
rxfp1relaxin/insulin-like family peptide receptor 10.037
angpt1angiopoietin 10.034
phox2bpaired-like homeobox 2b0.032
ptger1aprostaglandin E receptor 1, subtype EP1a0.032
trpv6transient receptor potential cation channel, subfamily V, member 60.030
zdhhc8bzinc finger, DHHC-type containing 8b0.030
jhdm1dajumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)0.030
smoc1SPARC related modular calcium binding 10.030
hdac4histone deacetylase 40.029
smg7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)0.029
pdcd11programmed cell death 110.029
stmn4stathmin-like 40.029
rdh8lretinol dehydrogenase 8 like0.028
dopey1dopey family member 10.028
rbfox1RNA binding protein, fox-1 homolog (C. elegans) 10.026
fgf24fibroblast growth factor 240.026
agrpagouti related protein homolog0.026
smtnbsmoothelin b0.025
pcsk5bproprotein convertase subtilisin/kexin type 5b0.024
ugt5a5UDP glucuronosyltransferase 5 family, polypeptide A50.024
spry4sprouty (Drosophila) homolog 40.024
hoxc6bhomeo box C6b0.024
slc16a1solute carrier family 16 (monocarboxylic acid transporters), member 10.024
lifrbleukemia inhibitory factor receptor alpha b0.023
ptgs1prostaglandin-endoperoxide synthase 10.023
mkxamohawk homeobox a0.022
lamc3laminin, gamma 30.021
plxnb2aplexin b2a0.021
tgfb2transforming growth factor, beta 20.021
bmperBMP binding endothelial regulator0.021
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.021
sema3fasemaphorin 3fa0.021
pax7bpaired box gene 7b0.020
nr4a2bnuclear receptor subfamily 4, group A, member 2b0.019
cdh6cadherin 60.018
mc5rbmelanocortin 5b receptor0.018
avpr1barginine vasopressin receptor 1B0.018
slc39a1solute carrier family 39 (zinc transporter), member 10.018
rbp7bretinol binding protein 7b, cellular0.017
tbpTATA box binding protein0.017
hapln1ahyaluronan and proteoglycan link protein 1a0.017
sumo2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.017
vegfcvascular endothelial growth factor c0.017
lhx6LIM homeobox 60.017
chrna4cholinergic receptor, nicotinic, alpha 40.016
rdh10aretinol dehydrogenase 10a0.016
mecomMDS1 and EVI1 complex locus0.016
il6stinterleukin 6 signal transducer0.016
plxna3plexin A30.016
vaspvasodilator-stimulated phosphoprotein0.015
abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 50.015
tmf1TATA element modulatory factor 10.015
ugt2a5UDP glucuronosyltransferase 2 family, polypeptide A50.014
tubgcp6tubulin, gamma complex associated protein 60.014
jam2ajunctional adhesion molecule 2a0.014
insrbinsulin receptor b0.014
bmpr1bbbone morphogenetic protein receptor, type 1bb0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
HLH54FCG5005 gene product from transcript CG5005-RA0.194
Mef2Myocyte enhancer factor 20.140
fasfaint sausage0.116
stumpsCG31317 gene product from transcript CG31317-RC0.100
wbwing blister0.096
LanB1CG7123 gene product from transcript CG7123-RA0.036
GripGlutamate receptor binding protein0.025
DadDaughters against dpp0.023
mewmultiple edematous wings0.023
zfh1Zn finger homeodomain 10.015
LanALaminin A0.014
HandCG18144 gene product from transcript CG18144-RA0.014
CG11592CG11592 gene product from transcript CG11592-RA0.013
MrtfMyocardin-related transcription factor0.013
plexBplexin B0.011
Pvf2PDGF- and VEGF-related factor 20.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism