The network for 'blood vessel endothelial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blood vessel endothelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.

NameDescriptionProbabilityFunc Analog Organism
mibmind bomb0.930
tbx1T-box 10.919
cdh2cadherin 2, neuronal0.757
her7hairy and enhancer of split related-70.662
tbx16T-box gene 160.477
tal1T-cell acute lymphocytic leukemia 10.412
gli2aGLI-Kruppel family member GLI2a0.358
kdrlkinase insert domain receptor like0.275
notch3notch homolog 30.250
fgf8afibroblast growth factor 8 a0.234
ptch1patched 10.195
krit1KRIT1, ankyrin repeat containing0.172
tbx24T-box 240.172
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.146
dll4delta-like 4 (Drosophila)0.140
wnt5bwingless-type MMTV integration site family, member 5b0.131
plcg1phospholipase C, gamma 10.115
hnf1baHNF1 homeobox Ba0.109
tp53tumor protein p530.098
ntlano tail a0.096
her3hairy-related 30.093
coblcordon-bleu homolog (mouse)0.085
fli1afriend leukemia integration 1a0.082
etv2ets variant gene 20.080
msgn1mesogenin 10.078
gata1aGATA binding protein 1a0.075
foxn4forkhead box N40.074
tbx5aT-box 5a0.070
nkx2.5NK2 transcription factor related 50.070
wnt11wingless-type MMTV integration site family, member 110.067
rad21RAD21 homolog (S. pombe)0.065
her12hairy-related 120.063
myod1myogenic differentiation 10.061
notch1anotch homolog 1a0.057
bmp4bone morphogenetic protein 40.056
sarsseryl-tRNA synthetase0.054
rxrgaretinoid x receptor, gamma a0.053
her15.1hairy and enhancer of split-related 15.10.049
tnnt2atroponin T2a, cardiac0.047
pdlim3bPDZ and LIM domain 3b0.043
cdx4caudal type homeo box transcription factor 40.042
cxcr4achemokine (C-X-C motif) receptor 4a0.041
cmlc1cardiac myosin light chain-10.040
her9hairy-related 90.038
shhasonic hedgehog a0.038
edn1endothelin 10.037
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.037
tnnc1atroponin C type 1a (slow)0.036
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.034
tbx6T-box gene 60.034
dusp5dual specificity phosphatase 50.033
scube2signal peptide, CUB domain, EGF-like 20.029
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.029
fancd2Fanconi anemia, complementation group D20.027
smad3bMAD, mothers against decapentaplegic homolog 3b (Drosophila)0.026
six4bsine oculis homeobox homolog 4b0.026
vsx2visual system homeobox 20.026
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.026
cmybtranscription factor cmyb0.023
flhfloating head0.023
has2hyaluronan synthase 20.022
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.022
fgfr1afibroblast growth factor receptor 1a0.022
supt6hsuppressor of Ty 6 homolog0.022
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.022
trpv4transient receptor potential cation channel, subfamily V, member 40.022
nrarpanotch-regulated ankyrin repeat protein a0.021
mychmyelocytomatosis oncogene homolog0.020
tbx20T-box 200.020
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.020
jag1bjagged 1b0.020
myf5myogenic factor 50.020
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.020
crb2acrumbs homolog 2a0.020
pld1aphospholipase D1a0.019
gbx2gastrulation brain homeo box 20.019
eya1eyes absent homolog 10.018
aldh1a2aldehyde dehydrogenase 1 family, member A20.018
cd99l2CD99 antigen-like 20.018
sesn1sestrin 10.018
gli1GLI-Kruppel family member 10.018
hey2hairy/enhancer-of-split related with YRPW motif 20.018
hoxb1bhomeo box B1b0.018
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.018
nppanatriuretic peptide precursor A0.017
gro2groucho 20.017
hhexhematopoietically expressed homeobox0.017
ndr2nodal-related 20.017
tbx18T-box 180.017
vegfaavascular endothelial growth factor Aa0.016
sox7SRY-box containing gene 70.016
unc45bunc-45 homolog B (C. elegans)0.016
birc2baculoviral IAP repeat-containing 20.016
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.016
fn1fibronectin 10.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Notch1Notch gene homolog 1 (Drosophila)1.000
Notch2Notch gene homolog 2 (Drosophila)0.999
Jag1jagged 10.996
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.991
Psen1presenilin 10.988
Efnb2ephrin B20.968
Dll1delta-like 1 (Drosophila)0.949
Foxc1forkhead box C10.752
Hand2heart and neural crest derivatives expressed transcript 20.632
Gata4GATA binding protein 40.605
Ctnnb1catenin (cadherin associated protein), beta 10.450
Dll4delta-like 4 (Drosophila)0.414
Hey2hairy/enhancer-of-split related with YRPW motif 20.409
Foxc2forkhead box C20.362
Itgb1integrin beta 1 (fibronectin receptor beta)0.349
Pax3paired box gene 30.339
Hes1hairy and enhancer of split 1 (Drosophila)0.259
Fgfr1fibroblast growth factor receptor 10.248
Psen2presenilin 20.243
Nos3nitric oxide synthase 3, endothelial cell0.212
Tgfb2transforming growth factor, beta 20.185
Zfpm2zinc finger protein, multitype 20.101
Rb1retinoblastoma 10.100
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.097
Ntf3neurotrophin 30.096
Fgfr2fibroblast growth factor receptor 20.091
Ptf1apancreas specific transcription factor, 1a0.085
Shhsonic hedgehog0.078
Chd7chromodomain helicase DNA binding protein 70.070
Vangl2vang-like 2 (van gogh, Drosophila)0.064
Pitx2paired-like homeodomain transcription factor 20.054
Fgf8fibroblast growth factor 80.054
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.051
Notch3Notch gene homolog 3 (Drosophila)0.048
Gja1gap junction protein, alpha 10.048
Egfl7EGF-like domain 70.045
Hand1heart and neural crest derivatives expressed transcript 10.042
Hspg2perlecan (heparan sulfate proteoglycan 2)0.039
Pkd1polycystic kidney disease 1 homolog0.038
Gli2GLI-Kruppel family member GLI20.037
Tbx1T-box 10.034
Vegfavascular endothelial growth factor A0.033
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.032
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.031
Ptpn11protein tyrosine phosphatase, non-receptor type 110.031
Lama5laminin, alpha 50.031
Jag2jagged 20.026
Ednraendothelin receptor type A0.023
Ptch1patched homolog 10.023
Sox9SRY-box containing gene 90.022
Hif1ahypoxia inducible factor 1, alpha subunit0.022
Nr2f2nuclear receptor subfamily 2, group F, member 20.020
Hey1hairy/enhancer-of-split related with YRPW motif 10.019
Foxo1forkhead box O10.019
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.017
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.017
Msx1homeobox, msh-like 10.016
Meox2mesenchyme homeobox 20.015
Cdkn1bcyclin-dependent kinase inhibitor 1B0.013
Zeb1zinc finger E-box binding homeobox 10.012
Zfp362zinc finger protein 3620.012
Bmp4bone morphogenetic protein 40.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism