The network for 'muscle cell fate determination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

muscle cell fate determination

The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.

NameDescriptionProbabilityFunc Analog Organism
tbx5aT-box 5a0.956
notch1anotch homolog 1a0.645
pax2apaired box gene 2a0.624
alcamaactivated leukocyte cell adhesion molecule a0.501
bmp4bone morphogenetic protein 40.471
tbx20T-box 200.458
smyd1bSET and MYND domain containing 1b0.410
jag1bjagged 1b0.354
cadm3cell adhesion molecule 30.279
tfap2atranscription factor AP-2 alpha0.239
hoxc6ahomeo box C6a0.225
mef2camyocyte enhancer factor 2ca0.224
cdh2cadherin 2, neuronal0.210
rereaarginine-glutamic acid dipeptide (RE) repeats a0.200
ttnatitin a0.198
ptch1patched 10.188
mibmind bomb0.183
gli1GLI-Kruppel family member 10.160
gata6GATA-binding protein 60.156
tbx2bT-box 2b0.145
ephb3aeph receptor B3a0.143
flot1flotillin 10.129
hand2heart and neural crest derivatives expressed transcript 20.128
hoxa9ahomeo box A9a0.121
tbx18T-box 180.118
hey2hairy/enhancer-of-split related with YRPW motif 20.114
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.102
vangl2vang-like 2 (van gogh, Drosophila)0.098
ptch2patched 20.094
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.094
dlx3bdistal-less homeobox gene 3b0.094
fgf10afibroblast growth factor 10a0.090
fn1fibronectin 10.087
slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.084
shhasonic hedgehog a0.083
lamb1alaminin, beta 1a0.080
mecomMDS1 and EVI1 complex locus0.078
dag1dystroglycan 10.075
mef2cbmyocyte enhancer factor 2cb0.073
unc45bunc-45 homolog B (C. elegans)0.070
tbx2aT-box gene 2a0.068
nkx2.5NK2 transcription factor related 50.068
xirp2axin actin-binding repeat containing 2a0.066
foxn4forkhead box N40.064
tbx1T-box 10.063
lhx3LIM homeobox 30.062
shisa2shisa homolog 2 (Xenopus laevis)0.059
ndrg4N-myc downstream regulated gene 40.058
plxna4plexin A40.058
foxc1aforkhead box C1a0.058
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.058
pax6bpaired box gene 6b0.057
traf4atnf receptor-associated factor 4a0.056
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.056
hoxb5ahomeo box B5a0.054
gata3GATA-binding protein 30.052
fgf24fibroblast growth factor 240.052
etv2ets variant gene 20.051
pcdh10bprotocadherin 10b0.048
lamb2laminin, beta 2 (laminin S)0.047
sall4sal-like 4 (Drosophila)0.047
tbx24T-box 240.044
vgll4lvestigial like 4 like0.043
tgfb3transforming growth factor, beta 30.042
robo3roundabout homolog 30.042
tbx5bT-box 5b0.039
six4bsine oculis homeobox homolog 4b0.039
nkx3.2NK3 homeobox 20.039
vcanaversican a0.038
myf5myogenic factor 50.037
kdrlkinase insert domain receptor like0.037
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.036
pitx3paired-like homeodomain transcription factor 30.036
foxd3forkhead box D30.036
rxrgaretinoid x receptor, gamma a0.036
hey1hairy/enhancer-of-split related with YRPW motif 10.035
lama4laminin, alpha 40.035
prox1prospero-related homeobox gene 10.035
evx1even-skipped homeobox 10.034
foxi1forkhead box I10.033
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.033
sox9aSRY-box containing gene 9a0.032
dyx1c1dyslexia susceptibility 1 candidate 10.032
pth2parathyroid hormone 20.032
kitakit receptor a0.032
dnmt4DNA (cytosine-5-)-methyltransferase 40.032
frem3Fras1 related extracellular matrix 30.031
cdh5cadherin 50.030
fli1afriend leukemia integration 1a0.029
neurod4neurogenic differentiation 40.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism