The network for 'regulation of peptidyl tyrosine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of peptidyl tyrosine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

NameDescriptionProbabilityFunc Analog Organism
trpm7transient receptor potential cation channel, subfamily M, member 70.641
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.544
ikzf1IKAROS family zinc finger 1 (Ikaros)0.480
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.441
mpxmyeloid-specific peroxidase0.437
osr2odd-skipped related 2 (Drosophila)0.403
card9caspase recruitment domain family, member 90.392
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.340
zgc:64051zgc:640510.339
il6stinterleukin 6 signal transducer0.338
cdh6cadherin 60.320
runx3runt-related transcription factor 30.310
ghragrowth hormone receptor a0.301
spna2spectrin alpha 20.291
si:dkey-8l13.4si:dkey-8l13.40.271
nod1nucleotide-binding oligomerization domain containing 10.245
kbpkif1-binding protein0.240
ltkleukocyte tyrosine kinase0.239
nrp2bneuropilin 2b0.237
cmybtranscription factor cmyb0.231
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.230
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.226
ighz2immunoglobulin heavy constant zeta20.220
fbln4fibulin 40.219
fn1bfibronectin 1b0.211
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.207
il6rinterleukin 6 receptor0.196
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.195
adcyap1aadenylate cyclase activating polypeptide 1a0.190
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.188
lef1lymphocyte enhancer binding factor 10.181
sox10SRY-box containing gene 100.179
entpd1ectonucleoside triphosphate diphosphohydrolase 10.169
fn1fibronectin 10.162
sdcbpsyndecan binding protein (syntenin)0.159
hgfbhepatocyte growth factor b0.156
tnfrsfatumor necrosis factor receptor superfamily, member a0.155
neurodneurogenic differentiation0.153
LOC555739serine/threonine-protein kinase LMTK1-like0.147
ptgs1prostaglandin-endoperoxide synthase 10.145
coro1acoronin, actin binding protein, 1A0.144
psen1presenilin 10.144
sb:cb429sb:cb4290.143
stat3signal transduction and activation of transcription 30.138
cxcr4bchemokine (C-X-C motif), receptor 4b0.137
atp2b4ATPase, Ca++ transporting, plasma membrane 40.136
nrp2aneuropilin 2a0.136
dlcdeltaC0.133
arpc1bactin related protein 2/3 complex, subunit 1B0.130
metmet proto-oncogene (hepatocyte growth factor receptor)0.129
itgb1aintegrin, beta 1a0.127
lyzlysozyme0.127
pfn1profilin 10.127
tpst1tyrosylprotein sulfotransferase 10.126
nrp1aneuropilin 1a0.126
igf1insulin-like growth factor 10.124
pax7bpaired box gene 7b0.124
mfn2mitofusin 20.123
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.123
hs6st1bheparan sulfate 6-O-sulfotransferase 1b0.122
slc4a4asolute carrier family 4, member 4a0.119
ahcyl1S-adenosylhomocysteine hydrolase-like 10.117
ccbe1collagen and calcium binding EGF domains 10.116
jag1bjagged 1b0.114
ntn2netrin 20.111
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.110
st8sia6ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 60.110
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.109
angptl2angiopoietin-like 20.109
nrg1neuregulin 10.109
msi1musashi homolog 1 (Drosophila)0.108
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.108
si:dkey-27i16.2si:dkey-27i16.20.107
iclp1invariant chain-like protein 10.107
irf9interferon regulatory factor 90.107
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.105
cotl1coactosin-like 1 (Dictyostelium)0.105
mitfamicrophthalmia-associated transcription factor a0.105
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.103
rhoubras homolog gene family, member Ub0.103
acheacetylcholinesterase0.103
llgl2lethal giant larvae homolog 2 (Drosophila)0.103
lims1LIM and senescent cell antigen-like domains 10.100
arl4abADP-ribosylation factor-like 4ab0.100
LOC100149353transient receptor potential cation channel subfamily M member 6-like0.100
rykreceptor-like tyrosine kinase0.099
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.098
tal1T-cell acute lymphocytic leukemia 10.096
si:ch211-89f7.4si:ch211-89f7.40.096
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.095
LOC557072caspase recruitment domain-containing protein 11-like0.094
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.094
lmx1b.1LIM homeobox transcription factor 1, beta 10.092
rcv1recoverin0.092
disp1dispatched homolog 1 (Drosophila)0.092
shbgsex hormone binding globulin0.091
prnprs3prion protein, related sequence 30.090
hoxb1ahomeo box B1a0.089
opn1sw1opsin 1 (cone pigments), short-wave-sensitive 10.088
col7a1lcollagen type VII alpha 1-like0.088
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
HLHm7E(spl) region transcript m70.771
E(spl)Enhancer of split0.613
Pi3K92ECG4141 gene product from transcript CG4141-RB0.608
HLHmbetaE(spl) region transcript mbeta0.576
HLHmdeltaE(spl) region transcript mdelta0.539
mbcmyoblast city0.465
scbscab0.424
htlheartless0.318
HLHmgammaE(spl) region transcript mgamma0.294
Socs36ESuppressor of cytokine signaling at 36E0.266
Src42ASrc oncogene at 42A0.261
HLHm3E(spl) region transcript m30.153
CblCG7037 gene product from transcript CG7037-RB0.140
shnschnurri0.131
drkdownstream of receptor kinase0.122
SaraSmad anchor for receptor activation0.115
chicoCG5686 gene product from transcript CG5686-RB0.097
rhorhomboid0.093
auxauxillin0.086
Src64BSrc oncogene at 64B0.084
SmoxSmad on X0.071
stumpsCG31317 gene product from transcript CG31317-RC0.060
wtswarts0.054
rlrolled0.051
rolsrolling pebbles0.050
RASSF8CG5053 gene product from transcript CG5053-RA0.049
howheld out wings0.048
inaDinactivation no afterpotential D0.045
krzkurtz0.045
HLHm5E(spl) region transcript m50.044
par-1CG8201 gene product from transcript CG8201-RA0.043
zfh1Zn finger homeodomain 10.043
phlpole hole0.042
Su(H)Suppressor of Hairless0.042
RalaRas-related protein0.042
KrnKeren0.038
slprslipper0.037
babobaboon0.036
argosCG4531 gene product from transcript CG4531-RA0.035
Btk29ABtk family kinase at 29A0.034
ninaCneither inactivation nor afterpotential C0.033
Adf1Adh transcription factor 10.031
CG12734CG12734 gene product from transcript CG12734-RA0.031
numbCG3779 gene product from transcript CG3779-RB0.031
malphaE(spl) region transcript malpha0.030
cv-2crossveinless 20.030
Tm1Tropomyosin 10.029
wocwithout children0.029
Stat92ESignal-transducer and activator of transcription protein at 92E0.028
SnooSno oncogene0.027
NFATNFAT homolog0.027
TomTwin of m40.027
m2E(spl) region transcript m20.027
scscute0.026
Atg1Autophagy-specific gene 10.026
fs(1)hfemale sterile (1) homeotic0.026
Fas2Fasciclin 20.026
ash2absent, small, or homeotic discs 20.025
CG5794CG5794 gene product from transcript CG5794-RB0.025
spasspastin0.025
Rac2CG8556 gene product from transcript CG8556-RA0.024
Pk61CProtein kinase 61C0.024
ctaconcertina0.023
eIF-4EEukaryotic initiation factor 4E0.022
ShcSHC-adaptor protein0.022
Tsf2Transferrin 20.021
RelRelish0.021
TORCCG6064 gene product from transcript CG6064-RA0.021
CG12424CG12424 gene product from transcript CG12424-RC0.020
sbbscribbler0.020
hppyhappyhour0.020
knknot0.020
kuzkuzbanian0.020
Akap200A kinase anchor protein 2000.019
ruroughoid0.019
hrghiiragi0.018
srpserpent0.018
NetBNetrin-B0.018
stepsteppke0.018
RagACG11968 gene product from transcript CG11968-RA0.017
nmonemo0.017
spispitz0.017
CG4030CG4030 gene product from transcript CG4030-RA0.017
CG3573CG3573 gene product from transcript CG3573-RA0.016
DadDaughters against dpp0.016
sogshort gastrulation0.016
ninaEneither inactivation nor afterpotential E0.016
Pvf1PDGF- and VEGF-related factor 10.016
SosSon of sevenless0.016
CG9247CG9247 gene product from transcript CG9247-RA0.016
CG14614CG14614 gene product from transcript CG14614-RA0.016
kek1kekkon-10.016
vvlventral veins lacking0.015
unkunkempt0.015
Vrp1Verprolin 10.015
tankyraseCG4719 gene product from transcript CG4719-RA0.015
ushu-shaped0.015
ChroChromator0.015
taitaiman0.015
WnkCG7177 gene product from transcript CG7177-RA0.014
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
GRB2growth factor receptor-bound protein 21.000
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.999
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.999
PLCG1phospholipase C, gamma 10.997
PTPN1protein tyrosine phosphatase, non-receptor type 10.996
SYKspleen tyrosine kinase0.996
SHC1SHC (Src homology 2 domain containing) transforming protein 10.995
GHRgrowth hormone receptor0.988
FGFR2fibroblast growth factor receptor 20.981
PTPRCprotein tyrosine phosphatase, receptor type, C0.976
NCK1NCK adaptor protein 10.974
BTKBruton agammaglobulinemia tyrosine kinase0.972
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.967
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.965
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.965
FGF1fibroblast growth factor 1 (acidic)0.952
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.941
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.934
LCKlymphocyte-specific protein tyrosine kinase0.926
GRB7growth factor receptor-bound protein 70.924
TEKTEK tyrosine kinase, endothelial0.921
TRAF1TNF receptor-associated factor 10.918
FHL2four and a half LIM domains 20.917
VEGFAvascular endothelial growth factor A0.915
FN1fibronectin 10.891
LATlinker for activation of T cells0.889
SPRR2Asmall proline-rich protein 2A0.885
VAV1vav 1 guanine nucleotide exchange factor0.884
TRAF2TNF receptor-associated factor 20.879
METmet proto-oncogene (hepatocyte growth factor receptor)0.861
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.852
PTK2PTK2 protein tyrosine kinase 20.845
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.825
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.812
BIRC3baculoviral IAP repeat containing 30.812
BCAR1breast cancer anti-estrogen resistance 10.810
PTPN6protein tyrosine phosphatase, non-receptor type 60.809
PLAUplasminogen activator, urokinase0.806
BCL2B-cell CLL/lymphoma 20.794
FGFR1fibroblast growth factor receptor 10.787
ICAM1intercellular adhesion molecule 10.785
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.772
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.754
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.745
NRP1neuropilin 10.725
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.723
NCKAP1NCK-associated protein 10.712
ESR1estrogen receptor 10.710
SOCS1suppressor of cytokine signaling 10.709
SNX9sorting nexin 90.700
EZRezrin0.682
AXLAXL receptor tyrosine kinase0.658
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.655
IL6interleukin 6 (interferon, beta 2)0.653
FADDFas (TNFRSF6)-associated via death domain0.615
BLNKB-cell linker0.610
EPHA2EPH receptor A20.609
CDC37cell division cycle 37 homolog (S. cerevisiae)0.607
CASP8caspase 8, apoptosis-related cysteine peptidase0.606
PTPRBprotein tyrosine phosphatase, receptor type, B0.602
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.591
IER3immediate early response 30.571
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.566
MTORmechanistic target of rapamycin (serine/threonine kinase)0.548
CCR5chemokine (C-C motif) receptor 50.542
TRADDTNFRSF1A-associated via death domain0.534
TAL1T-cell acute lymphocytic leukemia 10.527
CD44CD44 molecule (Indian blood group)0.527
VCAM1vascular cell adhesion molecule 10.522
NTRK1neurotrophic tyrosine kinase, receptor, type 10.516
SOCS3suppressor of cytokine signaling 30.514
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.502
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.492
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.489
MPDZmultiple PDZ domain protein0.488
CCL2chemokine (C-C motif) ligand 20.485
SH3BP2SH3-domain binding protein 20.482
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.478
CD28CD28 molecule0.467
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.466
FLNAfilamin A, alpha0.461
ENGendoglin0.456
RIN1Ras and Rab interactor 10.453
YAP1Yes-associated protein 10.439
PLAURplasminogen activator, urokinase receptor0.426
CASP10caspase 10, apoptosis-related cysteine peptidase0.419
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.416
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.395
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.391
SH2D4ASH2 domain containing 4A0.390
IL8interleukin 80.389
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.388
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.385
PTPN11protein tyrosine phosphatase, non-receptor type 110.380
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Il6stinterleukin 6 signal transducer0.992
Cd44CD44 antigen0.990
Ctnnb1catenin (cadherin associated protein), beta 10.987
Stat3signal transducer and activator of transcription 30.978
Ephb2Eph receptor B20.959
Tnftumor necrosis factor0.935
Emx1empty spiracles homolog 1 (Drosophila)0.926
Kitkit oncogene0.921
Smad3MAD homolog 3 (Drosophila)0.909
Ppargperoxisome proliferator activated receptor gamma0.907
Tlr4toll-like receptor 40.900
Dab1disabled homolog 1 (Drosophila)0.898
Foxn1forkhead box N10.884
Il10interleukin 100.864
Myd88myeloid differentiation primary response gene 880.851
Appamyloid beta (A4) precursor protein0.844
Notch1Notch gene homolog 1 (Drosophila)0.824
Plcg1phospholipase C, gamma 10.807
Ptpn11protein tyrosine phosphatase, non-receptor type 110.801
Cd28CD28 antigen0.789
Csf1colony stimulating factor 1 (macrophage)0.788
Dll1delta-like 1 (Drosophila)0.784
Inpp5dinositol polyphosphate-5-phosphatase D0.776
Axin1axin 10.776
Apcadenomatosis polyposis coli0.773
Leprleptin receptor0.767
Prf1perforin 1 (pore forming protein)0.762
SrcRous sarcoma oncogene0.755
Nos3nitric oxide synthase 3, endothelial cell0.753
Vangl2vang-like 2 (van gogh, Drosophila)0.748
Apoeapolipoprotein E0.743
Grb2growth factor receptor bound protein 20.735
Gsk3bglycogen synthase kinase 3 beta0.732
Il6interleukin 60.725
Lcklymphocyte protein tyrosine kinase0.712
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.711
Emx2empty spiracles homolog 2 (Drosophila)0.706
Mmp9matrix metallopeptidase 90.705
Slamf1signaling lymphocytic activation molecule family member 10.705
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.702
Ptk2PTK2 protein tyrosine kinase 20.662
Latlinker for activation of T cells0.644
Klklotho0.631
Rag1recombination activating gene 10.625
Ifnginterferon gamma0.621
CblCasitas B-lineage lymphoma0.609
Stat5asignal transducer and activator of transcription 5A0.603
Wnt7awingless-related MMTV integration site 7A0.583
Ptenphosphatase and tensin homolog0.544
Gli3GLI-Kruppel family member GLI30.542
Nos2nitric oxide synthase 2, inducible0.528
Trp53transformation related protein 530.525
Il1r1interleukin 1 receptor, type I0.510
Wnt5awingless-related MMTV integration site 5A0.504
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.496
Lhx3LIM homeobox protein 30.493
Gata5GATA binding protein 50.492
FasFas (TNF receptor superfamily member 6)0.490
Adam17a disintegrin and metallopeptidase domain 170.487
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.478
Itgb1integrin beta 1 (fibronectin receptor beta)0.447
Dvl3dishevelled 3, dsh homolog (Drosophila)0.446
Cdkn1bcyclin-dependent kinase inhibitor 1B0.421
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.419
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.416
Pgrprogesterone receptor0.412
Hes5hairy and enhancer of split 5 (Drosophila)0.412
Foxf1aforkhead box F1a0.406
Lhx1LIM homeobox protein 10.406
Prnpprion protein0.404
Esr1estrogen receptor 1 (alpha)0.402
Efnb2ephrin B20.394
Nodalnodal0.391
Sfrp2secreted frizzled-related protein 20.390
Tekendothelial-specific receptor tyrosine kinase0.388
Psen1presenilin 10.382
Bmp1bone morphogenetic protein 10.371
Egfrepidermal growth factor receptor0.365
Tbx3T-box 30.354
Ighimmunoglobulin heavy chain complex0.350
Ednrbendothelin receptor type B0.345
Smad6MAD homolog 6 (Drosophila)0.344
Kcnh3potassium voltage-gated channel, subfamily H (eag-related), member 30.338
Pax2paired box gene 20.337
Mtormechanistic target of rapamycin (serine/threonine kinase)0.326
Lyz2lysozyme 20.321
Icosinducible T-cell co-stimulator0.320
Flt4FMS-like tyrosine kinase 40.319
Nlrp3NLR family, pyrin domain containing 30.318
Foxp3forkhead box P30.315
Pax8paired box gene 80.314
Npy1rneuropeptide Y receptor Y10.313
Ptprcprotein tyrosine phosphatase, receptor type, C0.313
Cd19CD19 antigen0.310
S1pr1sphingosine-1-phosphate receptor 10.308
Dock1dedicator of cytokinesis 10.307
Plxnd1plexin D10.305
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.304
Itgb2integrin beta 20.303
Socs1suppressor of cytokine signaling 10.303
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nedd4neural precursor cell expressed, developmentally down-regulated 40.019
Ly86lymphocyte antigen 860.019
Hckhemopoietic cell kinase0.016
Nfibnuclear factor I/B0.013
Ripk3receptor-interacting serine-threonine kinase 30.013
Pld4phospholipase D family, member 40.012
Ptafrplatelet-activating factor receptor0.012
Slfn2schlafen 20.012
Rgs9regulator of G-protein signaling 90.012
Cxcr4chemokine (C-X-C motif) receptor 40.011
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.011
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.011
Neurl3neuralized homolog 3 (Drosophila)0.011
Sh2b3SH2B adaptor protein 30.011
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.011
Cd53Cd53 molecule0.011
Pla2g2cphospholipase A2, group IIC0.011
Il1r1interleukin 1 receptor, type I0.011
Grifingalectin-related inter-fiber protein0.011
Bmp6bone morphogenetic protein 60.011
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.011
Nr5a2nuclear receptor subfamily 5, group A, member 20.010
Csf1colony stimulating factor 1 (macrophage)0.010
Stat3signal transducer and activator of transcription 30.010
Jak1Janus kinase 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism