The network for 'cell migration to the midline involved in heart development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell migration to the midline involved in heart development

The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.

NameDescriptionProbabilityFunc Analog Organism
gata6GATA-binding protein 60.696
tbx20T-box 200.664
has2hyaluronan synthase 20.589
si:ch211-235f6.2si:ch211-235f6.20.575
gata5GATA-binding protein 50.549
tal1T-cell acute lymphocytic leukemia 10.517
gata2aGATA-binding protein 2a0.516
irx5airoquois homeobox protein 5a0.510
wu:fv91b12wu:fv91b120.485
pitx2paired-like homeodomain transcription factor 20.475
sox3SRY-box containing gene 30.415
tbx1T-box 10.409
robo3roundabout homolog 30.400
runx1runt-related transcription factor 10.333
kdrlkinase insert domain receptor like0.314
slit2slit (Drosophila) homolog 20.314
mespbmesoderm posterior b0.273
fn1fibronectin 10.267
mespamesoderm posterior a0.246
alas2aminolevulinate, delta-, synthetase 20.246
cmybtranscription factor cmyb0.240
her7hairy and enhancer of split related-70.200
spawsouthpaw0.189
sox4bSRY-box containing gene 4b0.182
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.171
nr2f2nuclear receptor subfamily 2, group F, member 20.164
hbbe1.1hemoglobin beta embryonic-1.10.152
igf1rainsulin-like growth factor 1a receptor0.149
tbx6T-box gene 60.145
slit1aslit homolog 1a (Drosophila)0.142
ndr2nodal-related 20.138
fli1afriend leukemia integration 1a0.134
lmo2LIM domain only 2 (rhombotin-like 1)0.132
pcdh8protocadherin 80.129
flt4fms-related tyrosine kinase 40.124
hand2heart and neural crest derivatives expressed transcript 20.121
foxa1forkhead box A10.120
sox19aSRY-box containing gene 19a0.109
sox19bSRY-box containing gene 19b0.106
nr2f1anuclear receptor subfamily 2, group F, member 1a0.106
foxa3forkhead box A30.100
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.096
cd99l2CD99 antigen-like 20.096
bmp2abone morphogenetic protein 2a0.093
slit1bslit homolog 1b (Drosophila)0.091
fezf2FEZ family zinc finger 20.091
alpialkaline phosphatase, intestinal0.086
tie1endothelium-specific receptor tyrosine kinase 10.086
pcdh10aprotocadherin 10a0.084
fgfrl1bfibroblast growth factor receptor-like 1b0.081
sox32SRY-box containing gene 320.081
tmem2transmembrane protein 20.080
zic2bzic family member 2 (odd-paired homolog, Drosophila) b0.080
gata3GATA-binding protein 30.077
foxd3forkhead box D30.075
spry4sprouty (Drosophila) homolog 40.075
hhexhematopoietically expressed homeobox0.074
edn1endothelin 10.074
cdh2cadherin 2, neuronal0.073
etv2ets variant gene 20.073
her1hairy-related 10.072
sox11aSRY-box containing gene 11a0.072
ventventral expressed homeobox0.071
tfap2atranscription factor AP-2 alpha0.070
drldraculin0.067
nkx2.5NK2 transcription factor related 50.066
zeb2azinc finger E-box binding homeobox 2a0.066
znf503zinc finger protein 5030.065
snai1bsnail homolog 1b (Drosophila)0.064
fgfr2fibroblast growth factor receptor 20.061
egr1early growth response 10.060
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.060
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.059
hspb12heat shock protein, alpha-crystallin-related, b120.057
neo1neogenin 10.053
myf5myogenic factor 50.053
hey2hairy/enhancer-of-split related with YRPW motif 20.053
tll1tolloid-like 10.053
mecomMDS1 and EVI1 complex locus0.050
pax2apaired box gene 2a0.046
aplnrbapelin receptor b0.046
lfnglunatic fringe homolog0.045
ripply1ripply10.045
alcambactivated leukocyte cell adhesion molecule b0.044
mef2cbmyocyte enhancer factor 2cb0.044
dlcdeltaC0.042
lingo1bleucine rich repeat and Ig domain containing 1b0.042
oepone-eyed pinhead0.042
sfrp1asecreted frizzled-related protein 1a0.042
igfbp3insulin-like growth factor binding protein 30.041
efnb3bephrin B3b0.041
angpt1angiopoietin 10.041
jag2jagged 20.040
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.040
spon2aspondin 2a, extracellular matrix protein0.039
acvr1bactivin A receptor, type IB0.039
aplnraapelin receptor a0.038
rargbretinoic acid receptor, gamma b0.038
hbae1hemoglobin alpha embryonic-10.037
rasgef1baRasGEF domain family, member 1Ba0.037
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Tgfb2transforming growth factor, beta 20.997
Hand2heart and neural crest derivatives expressed transcript 20.997
Mesp1mesoderm posterior 10.996
Rxraretinoid X receptor alpha0.996
Gata6GATA binding protein 60.994
Vegfavascular endothelial growth factor A0.993
Slit3slit homolog 3 (Drosophila)0.991
Ece1endothelin converting enzyme 10.982
Fgf8fibroblast growth factor 80.981
Pitx2paired-like homeodomain transcription factor 20.976
Foxc2forkhead box C20.964
Acvr1activin A receptor, type 10.960
Hey2hairy/enhancer-of-split related with YRPW motif 20.930
Jag1jagged 10.909
Zfpm2zinc finger protein, multitype 20.907
Bmp4bone morphogenetic protein 40.905
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.871
Robo2roundabout homolog 2 (Drosophila)0.779
Rararetinoic acid receptor, alpha0.774
Pax3paired box gene 30.765
Tbx1T-box 10.707
Hoxa3homeobox A30.694
Sox9SRY-box containing gene 90.635
Gata4GATA binding protein 40.608
Rarbretinoic acid receptor, beta0.607
Foxc1forkhead box C10.542
Ptpn11protein tyrosine phosphatase, non-receptor type 110.535
Fgfr1fibroblast growth factor receptor 10.517
Isl1ISL1 transcription factor, LIM/homeodomain0.486
Nrp1neuropilin 10.434
Smosmoothened homolog (Drosophila)0.420
Hand1heart and neural crest derivatives expressed transcript 10.404
Robo1roundabout homolog 1 (Drosophila)0.338
Meox2mesenchyme homeobox 20.308
Hey1hairy/enhancer-of-split related with YRPW motif 10.235
Klf3Kruppel-like factor 3 (basic)0.232
Prrx1paired related homeobox 10.226
Tcfap2atranscription factor AP-2, alpha0.224
Hoxa1homeobox A10.215
Rargretinoic acid receptor, gamma0.210
Ednraendothelin receptor type A0.210
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.207
Nos3nitric oxide synthase 3, endothelial cell0.188
Ntf3neurotrophin 30.187
Tgfbr2transforming growth factor, beta receptor II0.175
Nodalnodal0.166
Plxnd1plexin D10.138
Hhexhematopoietically expressed homeobox0.135
Slit2slit homolog 2 (Drosophila)0.124
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.119
Chrdchordin0.118
Prrx2paired related homeobox 20.113
Hoxa13homeobox A130.101
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.083
Ptk2PTK2 protein tyrosine kinase 20.078
Smad6MAD homolog 6 (Drosophila)0.057
Slit1slit homolog 1 (Drosophila)0.054
Shesrc homology 2 domain-containing transforming protein E0.049
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.048
Chd7chromodomain helicase DNA binding protein 70.045
Nkx2-6NK2 transcription factor related, locus 6 (Drosophila)0.043
Efna1ephrin A10.042
Gscgoosecoid homeobox0.039
Kdrkinase insert domain protein receptor0.038
Epha1Eph receptor A10.036
Sox4SRY-box containing gene 40.033
Gli2GLI-Kruppel family member GLI20.033
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.033
Hoxa2homeobox A20.033
Mkl2MKL/myocardin-like 20.031
Egfrepidermal growth factor receptor0.029
Eya1eyes absent 1 homolog (Drosophila)0.028
Gja5gap junction protein, alpha 50.027
Sox18SRY-box containing gene 180.025
Tbx3T-box 30.024
Sox7SRY-box containing gene 70.022
Bmpr1abone morphogenetic protein receptor, type 1A0.022
Adam17a disintegrin and metallopeptidase domain 170.021
Fshrfollicle stimulating hormone receptor0.021
Ptprbprotein tyrosine phosphatase, receptor type, B0.020
Gja1gap junction protein, alpha 10.020
Snai1snail homolog 1 (Drosophila)0.019
Gata5GATA binding protein 50.019
Msx1homeobox, msh-like 10.019
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.018
Gbx2gastrulation brain homeobox 20.017
Amhanti-Mullerian hormone0.017
Cdh5cadherin 50.017
Wnt3awingless-related MMTV integration site 3A0.017
Tcf21transcription factor 210.017
Fgfr2fibroblast growth factor receptor 20.016
Pparaperoxisome proliferator activated receptor alpha0.016
Lrp1low density lipoprotein receptor-related protein 10.016
Epha3Eph receptor A30.016
Ltbp1latent transforming growth factor beta binding protein 10.015
Cxcr7chemokine (C-X-C motif) receptor 70.015
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.014
Efnb2ephrin B20.014
Dll4delta-like 4 (Drosophila)0.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism