The network for 'cellular component maintenance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular component maintenance

The organization process that preserves a cellular component in a stable functional or structural state.

NameDescriptionProbabilityFunc Analog Organism
nlgn2aneuroligin 2a0.622
nlgn4bneuroligin 4b0.621
nlgn2bneuroligin 2b0.596
mbpmyelin basic protein0.509
mapk1mitogen-activated protein kinase 10.502
bmp4bone morphogenetic protein 40.380
LOC100003514protein kinase C alpha type-like0.219
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.215
mpzmyelin protein zero0.185
smad1MAD homolog 1 (Drosophila)0.171
shhasonic hedgehog a0.156
cdh6cadherin 60.144
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.139
trpm7transient receptor potential cation channel, subfamily M, member 70.131
frem2aFras1 related extracellular matrix protein 2a0.125
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.116
brd2abromodomain-containing 2a0.106
cdh10cadherin 10, type 2 (T2-cadherin)0.104
ntrk2aneurotrophic tyrosine kinase, receptor, type 2a0.101
nlgn3aneuroligin 3a0.098
il1binterleukin 1, beta and interleukin 1, beta0.096
ptpraprotein tyrosine phosphatase, receptor type, A0.096
mitfamicrophthalmia-associated transcription factor a0.092
mapk3mitogen-activated protein kinase 30.090
vcpvalosin containing protein0.082
LOC100007758novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)0.080
acvr1lactivin A receptor, type I like0.080
nrg1neuregulin 10.079
guca1cguanylate cyclase activator 1C0.077
lama5laminin, alpha 50.073
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.072
drd1dopamine receptor D10.071
gap43growth associated protein 430.070
esyt3extended synaptotagmin-like protein 30.069
mgllmonoglyceride lipase0.068
kitakit receptor a0.068
alcamaactivated leukocyte cell adhesion molecule a0.066
epb41l5erythrocyte membrane protein band 4.1 like 50.064
jag2jagged 20.063
pax7bpaired box gene 7b0.063
hnf1baHNF1 homeobox Ba0.061
npepl1aminopeptidase-like 10.059
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.059
csf3rcolony stimulating factor 3 receptor (granulocyte)0.057
cadm1acell adhesion molecule 1a0.056
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.056
ptpn6protein tyrosine phosphatase, non-receptor type 60.055
csrp1acysteine and glycine-rich protein 1a0.055
epcamepithelial cell adhesion molecule0.054
dab1adisabled homolog 1a (Drosophila)0.053
pls1plastin 1 (I isoform)0.053
ndrg1N-myc downstream regulated gene 10.053
LOC555504novel protocadherin protein0.052
arf2ADP-ribosylation factor 20.050
synpo2lbsynaptopodin 2-like b0.050
ef1aelongation factor 1-alpha0.049
myl1myosin, light chain 1, alkali; skeletal, fast0.049
ntrk2bneurotrophic tyrosine kinase, receptor, type 2b0.049
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.048
stat3signal transduction and activation of transcription 30.047
asb8ankyrin repeat and SOCS box-containing 80.047
enpp6ectonucleotide pyrophosphatase/phosphodiesterase 60.047
ctnnb1catenin (cadherin-associated protein), beta 10.047
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.046
pkp3plakophilin 30.045
sox9aSRY-box containing gene 9a0.044
cdh1cadherin 1, epithelial0.042
mmp9matrix metalloproteinase 90.042
scn1basodium channel, voltage-gated, type I, beta a0.040
entpd3ectonucleoside triphosphate diphosphohydrolase 30.040
abca12ATP-binding cassette, sub-family A (ABC1), member 120.040
bmp2bbone morphogenetic protein 2b0.039
hnf1bbHNF1 homeobox Bb0.039
ryr2aryanodine receptor 2a (cardiac)0.039
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.038
rcn1reticulocalbin 1, EF-hand calcium binding domain0.038
hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase0.038
fgf8afibroblast growth factor 8 a0.038
jam2ajunctional adhesion molecule 2a0.038
nadl1.1neural adhesion molecule L1.10.038
cacnb3acalcium channel, voltage-dependent, beta 3a0.037
plxnb2aplexin b2a0.037
lppLIM domain containing preferred translocation partner in lipoma0.036
acy3.2aspartoacylase (aminocyclase) 3.20.035
alcambactivated leukocyte cell adhesion molecule b0.035
ckmbcreatine kinase, muscle b0.035
mapk12mitogen-activated protein kinase 120.035
plp1bproteolipid protein 1b0.034
cntn2contactin 20.034
lmo7aLIM domain only 7a0.033
ube4bubiquitination factor E4B, UFD2 homolog (S. cerevisiae)0.033
prkczprotein kinase C, zeta0.033
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ina-1Protein INA-10.031
lex-1Protein LEX-10.027
vab-1Protein VAB-10.020
unc-73Protein UNC-730.015
snt-1Protein SNT-10.013
CELE_Y37A1B.17Protein Y37A1B.170.012
hsr-9Protein HSR-90.012
pat-3Protein PAT-30.010
C08B11.8Protein C08B11.80.010
F47A4.5Protein F47A4.50.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
beta-Specbeta Spectrin0.080
unc-104CG8566 gene product from transcript CG8566-RB0.077
Snap25Synapse protein 250.050
Dhc64CDynein heavy chain 64C0.044
Rac2CG8556 gene product from transcript CG8556-RA0.030
HiraCG12153 gene product from transcript CG12153-RA0.025
CG5720CG5720 gene product from transcript CG5720-RA0.022
psidinphagocyte signaling impaired0.021
jebjelly belly0.019
S6kRPS6-p70-protein kinase0.019
exo84CG6095 gene product from transcript CG6095-RA0.018
fwdfour wheel drive0.017
Arf79FADP ribosylation factor 79F0.016
AlkCG8250 gene product from transcript CG8250-RA0.016
endoAendophilin A0.016
Pde8Phosphodiesterase 80.016
trioCG18214 gene product from transcript CG18214-RA0.016
Hr51Hormone receptor 510.015
onecutCG1922 gene product from transcript CG1922-RA0.015
neuroliginCG13772 gene product from transcript CG13772-RA0.015
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.014
MrtfMyocardin-related transcription factor0.014
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.014
Klp68DKinesin-like protein at 68D0.014
Syx1ASyntaxin 1A0.014
rev7CG2948 gene product from transcript CG2948-RA0.014
Rab5Rab-protein 50.014
GluRIIAGlutamate receptor IIA0.014
RpI135RNA polymerase I 135kD subunit0.014
Spn27ASerpin 27A0.013
witwishful thinking0.013
Vhlvon Hippel-Lindau0.013
Su(var)2-10Suppressor of variegation 2-100.013
MTF-1Metal response element-binding Transcription Factor-10.012
Sop2Suppressor of profilin 20.012
PvrPDGF- and VEGF-receptor related0.012
trptransient receptor potential0.012
CG9063CG9063 gene product from transcript CG9063-RA0.012
CG12187CG12187 gene product from transcript CG12187-RA0.011
Nrx-1Neurexin 10.011
Fer248 related 20.011
ird1immune response deficient 10.011
rtGEFrho-type guanine exchange factor0.011
Pros54Proteasome 54kD subunit0.011
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.011
kat-60L1katanin p60-like 10.011
Rab3Rab-protein 30.011
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.010
EphrinCG1862 gene product from transcript CG1862-RA0.010
DscamDown syndrome cell adhesion molecule0.010
CG17082CG17082 gene product from transcript CG17082-RD0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.112
DNM2dynamin 20.064
SH3KBP1SH3-domain kinase binding protein 10.059
CTNND1catenin (cadherin-associated protein), delta 10.039
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.038
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.033
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.020
VEGFAvascular endothelial growth factor A0.017
WASLWiskott-Aldrich syndrome-like0.016
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.012
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.012
MARK3MAP/microtubule affinity-regulating kinase 30.012
SNX9sorting nexin 90.011
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Itgb1integrin beta 1 (fibronectin receptor beta)0.561
Lama5laminin, alpha 50.200
SrcRous sarcoma oncogene0.161
Ptk2PTK2 protein tyrosine kinase 20.123
Pacsin1protein kinase C and casein kinase substrate in neurons 10.115
Mapk3mitogen-activated protein kinase 30.083
Grb2growth factor receptor bound protein 20.079
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.060
Bcar1breast cancer anti-estrogen resistance 10.055
Cd151CD151 antigen0.051
Tgfbr2transforming growth factor, beta receptor II0.050
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.045
Itgb3integrin beta 30.041
Cx3cr1chemokine (C-X3-C) receptor 10.040
Stx12syntaxin 120.040
Vegfavascular endothelial growth factor A0.039
Myo6myosin VI0.039
Itga3integrin alpha 30.037
Nckap1lNCK associated protein 1 like0.035
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.035
FybFYN binding protein0.034
Ncf1neutrophil cytosolic factor 10.034
Vhlvon Hippel-Lindau tumor suppressor0.033
Ephb2Eph receptor B20.033
Ptprfprotein tyrosine phosphatase, receptor type, F0.030
Dlg4discs, large homolog 4 (Drosophila)0.029
Sh3gl2SH3-domain GRB2-like 20.029
Tjp1tight junction protein 10.029
Col4a3collagen, type IV, alpha 30.028
Mapk1mitogen-activated protein kinase 10.027
L1camL1 cell adhesion molecule0.027
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.027
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.027
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.026
Itgb2integrin beta 20.026
Ccdc64bcoiled-coil domain containing 64B0.025
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.025
Dlgap1discs, large (Drosophila) homolog-associated protein 10.025
Wwc1WW, C2 and coiled-coil domain containing 10.023
C1qacomplement component 1, q subcomponent, alpha polypeptide0.022
Laptm5lysosomal-associated protein transmembrane 50.021
Pdgfbplatelet derived growth factor, B polypeptide0.021
Dok1docking protein 10.020
Notch2Notch gene homolog 2 (Drosophila)0.020
Atp9aATPase, class II, type 9A0.020
Ptk7PTK7 protein tyrosine kinase 70.020
Tnks1bp1tankyrase 1 binding protein 10.020
Slit2slit homolog 2 (Drosophila)0.019
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.019
Smurf2SMAD specific E3 ubiquitin protein ligase 20.019
Col12a1collagen, type XII, alpha 10.019
Prkcbprotein kinase C, beta0.018
Cacnb3calcium channel, voltage-dependent, beta 3 subunit0.018
Wdr1WD repeat domain 10.018
Dlg2discs, large homolog 2 (Drosophila)0.018
Accn1amiloride-sensitive cation channel 1, neuronal (degenerin)0.018
Peg3paternally expressed 30.017
Baz1abromodomain adjacent to zinc finger domain 1A0.017
Rhoaras homolog gene family, member A0.017
Jam3junction adhesion molecule 30.017
Esrp2epithelial splicing regulatory protein 20.016
Mknk1MAP kinase-interacting serine/threonine kinase 10.016
Ctnnb1catenin (cadherin associated protein), beta 10.016
Hs1bp3HCLS1 binding protein 30.016
Epha2Eph receptor A20.016
Lyz2lysozyme 20.016
Dusp6dual specificity phosphatase 60.015
Creb3l1cAMP responsive element binding protein 3-like 10.015
Selplgselectin, platelet (p-selectin) ligand0.015
Itga6integrin alpha 60.015
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.015
WaslWiskott-Aldrich syndrome-like (human)0.015
Ptk2bPTK2 protein tyrosine kinase 2 beta0.015
Itgb4integrin beta 40.015
Lmnalamin A0.015
Pfn2profilin 20.015
Aplp1amyloid beta (A4) precursor-like protein 10.015
Map4k1mitogen-activated protein kinase kinase kinase kinase 10.015
Chpfchondroitin polymerizing factor0.015
Rasal3RAS protein activator like 30.015
Nos3nitric oxide synthase 3, endothelial cell0.014
Esrp1epithelial splicing regulatory protein 10.014
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.014
Inainternexin neuronal intermediate filament protein, alpha0.014
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.013
Numbnumb gene homolog (Drosophila)0.013
Capn5calpain 50.013
Npy1rneuropeptide Y receptor Y10.013
Arhgap1Rho GTPase activating protein 10.013
Lcp2lymphocyte cytosolic protein 20.013
Arhgap31Rho GTPase activating protein 310.013
Lrp5low density lipoprotein receptor-related protein 50.013
Ptgfrnprostaglandin F2 receptor negative regulator0.012
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.012
Pld4phospholipase D family, member 40.012
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Sh3gl2SH3-domain GRB2-like 20.114
Pdk2pyruvate dehydrogenase kinase, isozyme 20.047
Gria2glutamate receptor, ionotropic, AMPA 20.035
Nucb1nucleobindin 10.034
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.033
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.033
Mapk3mitogen activated protein kinase 30.032
Stxbp1syntaxin binding protein 10.032
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.031
Gna12guanine nucleotide binding protein (G protein) alpha 120.030
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.029
March8membrane-associated ring finger (C3HC4) 80.028
CamkvCaM kinase-like vesicle-associated0.028
Gcc2GRIP and coiled-coil domain containing 20.028
Sorbs2sorbin and SH3 domain containing 20.027
Tecrtrans-2,3-enoyl-CoA reductase0.027
Ucp2uncoupling protein 2 (mitochondrial, proton carrier)0.024
Bin1bridging integrator 10.024
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.023
Sept6septin 60.023
Fam69bfamily with sequence similarity 69, member B0.021
Nrcamneuronal cell adhesion molecule0.021
Mapk1mitogen activated protein kinase 10.020
Sptbn2spectrin, beta, non-erythrocytic 20.019
Cdc27cell division cycle 27 homolog (S. cerevisiae)0.019
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.018
Prkcaprotein kinase C, alpha0.018
Sptan1spectrin, alpha, non-erythrocytic 10.018
Dync1i2dynein cytoplasmic 1 intermediate chain 20.018
Lcp1lymphocyte cytosolic protein 10.018
Prkacaprotein kinase, cAMP-dependent, catalytic, alpha0.017
Inainternexin neuronal intermediate filament protein, alpha0.017
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.017
C1qccomplement component 1, q subcomponent, C chain0.016
Nlgn3neuroligin 30.016
Itgb2integrin, beta 20.016
Ap3s1adaptor-related protein complex 3, sigma 1 subunit0.016
SvopSV2 related protein0.016
Dlgap1discs, large (Drosophila) homolog-associated protein 10.016
Pld4phospholipase D family, member 40.016
Faahfatty acid amide hydrolase0.016
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.016
Rab15RAB15, member RAS oncogene family0.016
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.015
Grip1glutamate receptor interacting protein 10.015
Itgb4integrin, beta 40.015
Gakcyclin G associated kinase0.015
Cldn4claudin 40.015
Lynx1Ly6/neurotoxin 10.015
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.015
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.015
Dctn5dynactin 50.015
Ate1arginyltransferase 10.015
Rab11bRAB11B, member RAS oncogene family0.015
Cnrip1cannabinoid receptor interacting protein 10.015
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.015
Necap1NECAP endocytosis associated 10.015
Emr1EGF-like module containing, mucin-like, hormone receptor-like 10.014
Exoc7exocyst complex component 70.014
Lin7blin-7 homolog b (C. elegans)0.014
Slc12a5solute carrier family 12 (potassium-chloride transporter), member 50.014
Ak1adenylate kinase 10.014
AxlAxl receptor tyrosine kinase0.014
Ptpn18protein tyrosine phosphatase, non-receptor type 180.014
Cept1choline/ethanolamine phosphotransferase 10.014
Itsn1intersectin 1 (SH3 domain protein)0.014
RGD1306772similar to RIKEN cDNA 1110008J030.014
Robo2roundabout homolog 2 (Drosophila)0.014
Gng10guanine nucleotide binding protein (G protein), gamma 100.014
Tmco3transmembrane and coiled-coil domains 30.014
Folr2folate receptor 2 (fetal)0.014
Cpt1acarnitine palmitoyltransferase 1a, liver0.013
Scamp2secretory carrier membrane protein 20.013
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.013
Itgamintegrin, alpha M0.013
Lamp2lysosomal-associated membrane protein 20.013
Gria3glutamate receptor, ionotrophic, AMPA 30.013
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.013
Hdac11histone deacetylase 110.013
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.013
Plscr3phospholipid scramblase 30.013
Herc3hect domain and RLD 30.013
Prickle2prickle homolog 2 (Drosophila)0.013
Prlrprolactin receptor0.013
Shroom2shroom family member 20.013
Grm3glutamate receptor, metabotropic 30.013
Ppp1r9aprotein phosphatase 1, regulatory (inhibitor) subunit 9A0.013
Ube2d2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.013
Smek1SMEK homolog 1, suppressor of mek1 (Dictyostelium)0.013
Synrgsynergin, gamma0.013
Efnb2ephrin B20.013
CartptCART prepropeptide0.013
Dlg3discs, large homolog 3 (Drosophila)0.013
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.013
Grik2glutamate receptor, ionotropic, kainate 20.013
Arf6ADP-ribosylation factor 60.013
Eef1a2eukaryotic translation elongation factor 1 alpha 20.012
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism