The network for 'nephron morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nephron morphogenesis

The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.

NameDescriptionProbabilityFunc Analog Organism
osr2odd-skipped related 2 (Drosophila)0.964
wt1bwilms tumor 1b0.943
wnt5bwingless-type MMTV integration site family, member 5b0.861
pax2apaired box gene 2a0.852
spry1sprouty homolog 1 (Drosophila)0.816
her12hairy-related 120.803
foxd3forkhead box D30.798
bmp2abone morphogenetic protein 2a0.788
gyltl1bglycosyltransferase-like 1b0.763
eya1eyes absent homolog 10.761
sim1asingle-minded homolog 1a (Drosophila)0.748
gbx2gastrulation brain homeo box 20.712
bmp2bbone morphogenetic protein 2b0.709
shhasonic hedgehog a0.688
aplnrbapelin receptor b0.681
hnf1bbHNF1 homeobox Bb0.677
wnt1wingless-type MMTV integration site family, member 10.654
hoxa9bhomeo box A9b0.647
bmp4bone morphogenetic protein 40.635
wnt10awingless-type MMTV integration site family, member 10a0.633
wnt2bawingless-type MMTV integration site family, member 2Ba0.619
hoxd4ahomeo box D4a0.602
notch1anotch homolog 1a0.577
tbx1T-box 10.575
lhx1aLIM homeobox 1a0.543
pcdh8protocadherin 80.539
hmx1H6 homeo box 10.527
mecomMDS1 and EVI1 complex locus0.518
coblcordon-bleu homolog (mouse)0.499
aldh1a2aldehyde dehydrogenase 1 family, member A20.498
dkk1bdickkopf 1b0.476
hmx3homeo box (H6 family) 30.462
wnt3awingless-type MMTV integration site family, member 3A0.459
sox9bSRY-box containing gene 9b0.447
nr2e1nuclear receptor subfamily 2, group E, member 10.437
fgf10afibroblast growth factor 10a0.421
lrrc50leucine rich repeat containing 500.416
msxbmuscle segment homeobox B0.413
prdm1aPR domain containing 1a, with ZNF domain0.409
ism1isthmin 10.407
wt1awilms tumor 1a0.406
fgf3fibroblast growth factor 30.398
six4asine oculis homeobox homolog 4a0.372
osr1odd-skipped related 1 (Drosophila)0.372
her15.1hairy and enhancer of split-related 15.10.355
hmx4H6 family homeobox 40.350
spry2sprouty homolog 20.339
six4bsine oculis homeobox homolog 4b0.337
pea3ETS-domain transcription factor pea30.336
sox21aSRY-box containing gene 21a0.329
hoxa13bhomeo box A13b0.316
hs3st3b1aheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a0.301
wnt2bbwingless-type MMTV integration site family, member 2Bb0.295
atoh1aatonal homolog 1a0.294
fgf17fibroblast growth factor 170.287
dusp6dual specificity phosphatase 60.283
myod1myogenic differentiation 10.276
etv2ets variant gene 20.267
jag2jagged 20.266
pax8paired box gene 80.264
notch3notch homolog 30.262
snai1asnail homolog 1a (Drosophila)0.254
nkx3.2NK3 homeobox 20.250
foxj1aforkhead box J1a0.248
hmx2H6 family homeobox 20.238
wnt4awingless-type MMTV integration site family, member 4a0.238
lef1lymphocyte enhancer binding factor 10.238
eya4eyes absent homolog 4 (Drosophila)0.225
hoxc6ahomeo box C6a0.222
klf4Kruppel-like factor 40.221
wnt9bwingless-type MMTV integration site family, member 9B0.221
foxo3bforkhead box O3b0.215
six1bsine oculis homeobox homolog 1b0.215
ptgs1prostaglandin-endoperoxide synthase 10.212
robo3roundabout homolog 30.202
ndr2nodal-related 20.197
hoxa9ahomeo box A9a0.190
foxn4forkhead box N40.187
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.187
lzts2aleucine zipper, putative tumor suppressor 2a0.178
tbx5aT-box 5a0.175
gdnfglial cell derived neurotrophic factor0.175
prrx1bpaired related homeobox 1b0.168
hoxd9ahomeo box D9a0.167
sox9aSRY-box containing gene 9a0.167
dlx6adistal-less homeobox gene 6a0.165
hoxd12ahomeo box D12a0.164
grhl2agrainyhead-like 2a (Drosophila)0.162
mesp2mesoderm posterior 2 homolog (mouse)0.161
hoxd13ahomeo box D13a0.157
vegfaavascular endothelial growth factor Aa0.156
her5hairy-related 50.151
pitx3paired-like homeodomain transcription factor 30.147
wnt3wingless-type MMTV integration site family, member 30.146
epb4.1l4erythrocyte protein band 4.1-like 40.144
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
cicubitus interruptus0.994
HLHmdeltaE(spl) region transcript mdelta0.949
HLHm7E(spl) region transcript m70.914
E(spl)Enhancer of split0.777
eyaeyes absent0.766
bowlbrother of odd with entrails limited0.738
HLHmbetaE(spl) region transcript mbeta0.725
slp1sloppy paired 10.689
emcextra macrochaetae0.650
HLHm3E(spl) region transcript m30.631
malphaE(spl) region transcript malpha0.583
Abd-BAbdominal B0.575
HLHmgammaE(spl) region transcript mgamma0.559
m2E(spl) region transcript m20.519
EgfrEpidermal growth factor receptor0.494
oddodd skipped0.463
DadDaughters against dpp0.433
sosine oculis0.423
argosCG4531 gene product from transcript CG4531-RA0.381
bibbig brain0.348
18w18 wheeler0.252
opaodd paired0.247
osaCG7467 gene product from transcript CG7467-RD0.223
emsempty spiracles0.202
nocno ocelli0.200
HcfHost cell factor0.181
dallydivision abnormally delayed0.149
bab2CG9102 gene product from transcript CG9102-RA0.140
eveeven skipped0.138
gcmglial cells missing0.133
elBelbow B0.122
sogshort gastrulation0.120
JIL-1CG6297 gene product from transcript CG6297-RA0.116
bab1bric a brac 10.107
slp2sloppy paired 20.106
TomTwin of m40.105
dvedefective proventriculus0.104
HLHm5E(spl) region transcript m50.102
hipkhomeodomain interacting protein kinase0.102
taptarget of Poxn0.092
CatsupCatecholamines up0.091
RhoGAP100FCG1976 gene product from transcript CG1976-RB0.088
aopanterior open0.079
MadMothers against dpp0.073
Myd88CG2078 gene product from transcript CG2078-RA0.071
vvlventral veins lacking0.070
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 21.000
CUL3cullin 30.969
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.909
FGFR1fibroblast growth factor receptor 10.847
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.773
FGF10fibroblast growth factor 100.764
WNK4WNK lysine deficient protein kinase 40.750
KLHL3kelch-like 3 (Drosophila)0.721
FGF1fibroblast growth factor 1 (acidic)0.682
FSTL1follistatin-like 10.659
KLHL12kelch-like 12 (Drosophila)0.637
BMPR1Abone morphogenetic protein receptor, type IA0.599
NR4A1nuclear receptor subfamily 4, group A, member 10.529
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.506
SMAD3SMAD family member 30.497
PKD2polycystic kidney disease 2 (autosomal dominant)0.440
MEIS1Meis homeobox 10.408
MEIS2Meis homeobox 20.398
NKX2-1NK2 homeobox 10.340
PLCG1phospholipase C, gamma 10.329
PKD1polycystic kidney disease 1 (autosomal dominant)0.326
PAX8paired box 80.318
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.285
NRP1neuropilin 10.278
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.240
NR4A3nuclear receptor subfamily 4, group A, member 30.228
SOX2SRY (sex determining region Y)-box 20.220
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.218
DAPK1death-associated protein kinase 10.214
TIMP3TIMP metallopeptidase inhibitor 30.209
FGF8fibroblast growth factor 8 (androgen-induced)0.195
TSC22D4TSC22 domain family, member 40.175
NR4A2nuclear receptor subfamily 4, group A, member 20.166
ADAM17ADAM metallopeptidase domain 170.162
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.154
MEOX1mesenchyme homeobox 10.152
FGF4fibroblast growth factor 40.150
MAGED2melanoma antigen family D, 20.128
GLIS2GLIS family zinc finger 20.125
KLHL2kelch-like 2, Mayven (Drosophila)0.119
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.119
FGF18fibroblast growth factor 180.114
WNT1wingless-type MMTV integration site family, member 10.103
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.098
BCL2L1BCL2-like 10.098
PAX2paired box 20.080
CSNK1Ecasein kinase 1, epsilon0.074
COL2A1collagen, type II, alpha 10.071
HOXB5homeobox B50.068
BMP7bone morphogenetic protein 70.067
BMP2bone morphogenetic protein 20.065
BHLHE40basic helix-loop-helix family, member e400.059
NGFRnerve growth factor receptor0.056
FGF3fibroblast growth factor 30.055
HOXA11homeobox A110.052
TGFBR1transforming growth factor, beta receptor 10.051
PAX3paired box 30.050
HMGA2high mobility group AT-hook 20.049
HNF1AHNF1 homeobox A0.045
BMP4bone morphogenetic protein 40.044
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.044
HOXA10homeobox A100.043
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.041
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.040
SOX1SRY (sex determining region Y)-box 10.039
SNAI1snail homolog 1 (Drosophila)0.039
DVL1dishevelled, dsh homolog 1 (Drosophila)0.039
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.038
FOXA2forkhead box A20.036
DVL3dishevelled, dsh homolog 3 (Drosophila)0.036
PAPPApregnancy-associated plasma protein A, pappalysin 10.035
SIM2single-minded homolog 2 (Drosophila)0.034
LBX1ladybird homeobox 10.033
FGF2fibroblast growth factor 2 (basic)0.033
PARVAparvin, alpha0.033
FGFR3fibroblast growth factor receptor 30.031
NFE2L2nuclear factor (erythroid-derived 2)-like 20.031
HOXD13homeobox D130.031
FGF7fibroblast growth factor 70.030
TAOK1TAO kinase 10.030
LMO4LIM domain only 40.029
TRPC1transient receptor potential cation channel, subfamily C, member 10.029
CLDN4claudin 40.029
INHBBinhibin, beta B0.028
FRS2fibroblast growth factor receptor substrate 20.028
DUSP6dual specificity phosphatase 60.028
NEDD4neural precursor cell expressed, developmentally down-regulated 40.026
HES2hairy and enhancer of split 2 (Drosophila)0.026
PRMT6protein arginine methyltransferase 60.026
WNT7Awingless-type MMTV integration site family, member 7A0.024
MED28mediator complex subunit 280.023
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.023
TGFB3transforming growth factor, beta 30.023
PAX7paired box 70.023
TGFB2transforming growth factor, beta 20.023
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax2paired box gene 21.000
Fgfr2fibroblast growth factor receptor 21.000
Hoxd11homeobox D111.000
Lhx1LIM homeobox protein 11.000
Bcl2B-cell leukemia/lymphoma 21.000
Gli3GLI-Kruppel family member GLI31.000
Hoxa11homeobox A110.999
Wt1Wilms tumor 1 homolog0.999
Foxc1forkhead box C10.999
Fgf8fibroblast growth factor 80.999
Otx2orthodenticle homolog 2 (Drosophila)0.999
Pax8paired box gene 80.998
Retret proto-oncogene0.998
Foxc2forkhead box C20.997
Tbx1T-box 10.997
Bmp4bone morphogenetic protein 40.996
Emx2empty spiracles homolog 2 (Drosophila)0.996
Hand2heart and neural crest derivatives expressed transcript 20.996
Pbx1pre B-cell leukemia transcription factor 10.996
Tcf21transcription factor 210.995
Gdnfglial cell line derived neurotrophic factor0.994
Pitx2paired-like homeodomain transcription factor 20.990
Smad6MAD homolog 6 (Drosophila)0.990
Tbx3T-box 30.989
Ren1renin 1 structural0.988
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.986
Tbx2T-box 20.985
Gli2GLI-Kruppel family member GLI20.985
Nr5a1nuclear receptor subfamily 5, group A, member 10.981
Hand1heart and neural crest derivatives expressed transcript 10.979
Ctnnb1catenin (cadherin associated protein), beta 10.978
Pax3paired box gene 30.977
Isl1ISL1 transcription factor, LIM/homeodomain0.976
Rargretinoic acid receptor, gamma0.975
Msx1homeobox, msh-like 10.975
Jag1jagged 10.972
Eya1eyes absent 1 homolog (Drosophila)0.971
Hes1hairy and enhancer of split 1 (Drosophila)0.966
Otx1orthodenticle homolog 1 (Drosophila)0.966
Hoxa1homeobox A10.965
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.957
Lef1lymphoid enhancer binding factor 10.950
Bmp7bone morphogenetic protein 70.949
Tgfb2transforming growth factor, beta 20.945
Hoxd3homeobox D30.942
Fgfr1fibroblast growth factor receptor 10.942
Hoxb6homeobox B60.941
Hoxd13homeobox D130.941
Dkk1dickkopf homolog 1 (Xenopus laevis)0.940
Ror2receptor tyrosine kinase-like orphan receptor 20.938
Hoxd9homeobox D90.934
Hoxa2homeobox A20.926
Hoxd4homeobox D40.925
Hoxa9homeobox A90.923
Hoxb3homeobox B30.923
Gata6GATA binding protein 60.915
Bnc1basonuclin 10.908
Ascl1achaete-scute complex homolog 1 (Drosophila)0.902
Wnt4wingless-related MMTV integration site 40.895
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.890
Rxraretinoid X receptor alpha0.889
Sox2SRY-box containing gene 20.880
Meox2mesenchyme homeobox 20.863
Rarbretinoic acid receptor, beta0.863
Foxa2forkhead box A20.861
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.855
Sox7SRY-box containing gene 70.842
Hoxb5homeobox B50.842
Foxg1forkhead box G10.840
En1engrailed 10.837
Hoxc5homeobox C50.824
Wnt5awingless-related MMTV integration site 5A0.812
Wnt6wingless-related MMTV integration site 60.811
Gbx2gastrulation brain homeobox 20.808
Gata4GATA binding protein 40.799
Gli1GLI-Kruppel family member GLI10.795
Hoxc4homeobox C40.792
Gas1growth arrest specific 10.790
Hoxa10homeobox A100.790
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.785
Hes5hairy and enhancer of split 5 (Drosophila)0.781
Rararetinoic acid receptor, alpha0.772
Hoxa13homeobox A130.767
Foxd2forkhead box D20.762
Efnb2ephrin B20.762
Hoxa3homeobox A30.758
Nos3nitric oxide synthase 3, endothelial cell0.752
Hoxd8homeobox D80.751
Lmx1bLIM homeobox transcription factor 1 beta0.751
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.748
Pax6paired box gene 60.747
Hoxb4homeobox B40.745
Vegfavascular endothelial growth factor A0.734
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.721
Hoxb2homeobox B20.715
Hoxd10homeobox D100.711
Flt4FMS-like tyrosine kinase 40.711
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nek9NIMA (never in mitosis gene a)- related kinase 90.078
Lims1LIM and senescent cell antigen-like domains 10.035
Acacbacetyl-Coenzyme A carboxylase beta0.032
Hoxc4homeo box C40.030
Il1r1interleukin 1 receptor, type I0.027
Trhr2thyrotropin releasing hormone receptor 20.024
Prrx1paired related homeobox 10.024
Igf2insulin-like growth factor 20.023
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.022
Glra1glycine receptor, alpha 10.022
Prph2peripherin 20.022
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.022
Clec11aC-type lectin domain family 11, member a0.021
Prdm2PR domain containing 2, with ZNF domain0.021
Ece1endothelin converting enzyme 10.019
C4bcomplement component 4B (Chido blood group)0.019
Cngb1cyclic nucleotide gated channel beta 10.018
Ddr1discoidin domain receptor tyrosine kinase 10.018
Gjd2gap junction protein, delta 20.017
Tpsb2tryptase beta 20.016
Cntfrciliary neurotrophic factor receptor0.016
Igfbp3insulin-like growth factor binding protein 30.016
Nos3nitric oxide synthase 3, endothelial cell0.016
Insrrinsulin receptor-related receptor0.015
Galr2galanin receptor 20.015
Gna15guanine nucleotide binding protein, alpha 150.015
Flt1FMS-related tyrosine kinase 10.014
Krt5keratin 50.014
Nr5a1nuclear receptor subfamily 5, group A, member 10.014
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.014
Wnt6wingless-type MMTV integration site family, member 60.013
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.013
Srd5a2steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)0.013
Igtpinterferon gamma induced GTPase0.013
Muc1mucin 1, cell surface associated0.013
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.013
Agtr2angiotensin II receptor, type 20.013
Sod3superoxide dismutase 3, extracellular0.012
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.012
Sardhsarcosine dehydrogenase0.012
Ascl1achaete-scute complex homolog 1 (Drosophila)0.012
Baiap2BAI1-associated protein 20.012
Tln1talin 10.012
Jak2Janus kinase 20.011
Tgfbr2transforming growth factor, beta receptor II0.011
Onecut1one cut homeobox 10.011
Igfbp5insulin-like growth factor binding protein 50.011
Itpr2inositol 1,4,5-triphosphate receptor, type 20.011
Rnf213ring finger protein 2130.011
Dctn4dynactin 40.011
Gpr20G protein-coupled receptor 200.011
Ptger3prostaglandin E receptor 3 (subtype EP3)0.010
St8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.010
Tcf12transcription factor 120.010
Irs1insulin receptor substrate 10.010
Sox17SRY (sex determining region Y)-box 170.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism