The network for 'establishment or maintenance of polarity of embryonic epithelium' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment or maintenance of polarity of embryonic epithelium

Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.

NameDescriptionProbabilityFunc Analog Organism
crb2acrumbs homolog 2a0.858
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.523
epb41l5erythrocyte membrane protein band 4.1 like 50.447
s1pr2sphingosine-1-phosphate receptor 20.425
prkciprotein kinase C, iota0.315
mibmind bomb0.279
wnt7bbwingless-type MMTV integration site family, member 7Bb0.270
vangl2vang-like 2 (van gogh, Drosophila)0.252
dlg1discs, large (Drosophila) homolog 10.227
gpc4glypican 40.210
lamc1laminin, gamma 10.181
apcadenomatosis polyposis coli0.170
disp1dispatched homolog 1 (Drosophila)0.153
scribscribbled homolog (Drosophila)0.136
hpcahippocalcin0.122
utrnutrophin0.122
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.113
pde10aphosphodiesterase 10A0.113
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.088
sb:cb472sb:cb4720.086
dpysl2bdihydropyrimidinase-like 2b0.083
stilTAL1 (SCL) interrupting locus0.080
LOC100003514protein kinase C alpha type-like0.074
skianuclear oncoprotein skia0.072
wnt3wingless-type MMTV integration site family, member 30.067
aldh4a1aldehyde dehydrogenase 4 family, member A10.065
fam43bfamily with sequence similarity 43, member B0.065
guca1cguanylate cyclase activator 1C0.064
suv420h2suppressor of variegation 4-20 homolog 2 (Drosophila)0.063
lmbrd2aLMBR1 domain containing 2a0.060
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.060
slc45a2solute carrier family 45, member 20.060
si:ch211-232m7.1si:ch211-232m7.10.059
tnikbTRAF2 and NCK interacting kinase b0.059
slc37a4asolute carrier family 37 (glucose-6-phosphate transporter), member 4a0.058
mxi1max interacting protein0.055
b4galt4UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 40.055
mapk1mitogen-activated protein kinase 10.055
ccm2cerebral cavernous malformation 20.054
dctn1adynactin 1a0.053
insrbinsulin receptor b0.051
zgc:110298zgc:1102980.049
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.048
pkp2plakophilin 20.048
cyp2aa4cytochrome P450, family 2, subfamily AA, polypeptide 40.047
slc1a4solute carrier family 1 (glutamate/neutral amino acid transporter), member 40.046
dzip1DAZ interacting protein 10.045
acp5bacid phosphatase 5b, tartrate resistant0.044
zgc:112986zgc:1129860.043
zgc:112180zgc:1121800.043
cry2bcryptochrome 2b0.042
ilkintegrin linked kinase0.041
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.040
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.039
oxsr1boxidative-stress responsive 1b0.038
prkceaprotein kinase C, epsilon a0.038
axin1axin 10.038
castcalpastatin0.037
sardhsarcosine dehydrogenase0.037
abca5ATP-binding cassette, sub-family A (ABC1), member 50.037
lrrfip2leucine rich repeat (in FLII) interacting protein 20.037
crb3bcrumbs homolog 3b0.037
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.036
chmchoroideremia0.035
ankrd12ankyrin repeat domain 120.035
plcg1phospholipase C, gamma 10.035
si:ch211-197h24.9si:ch211-197h24.90.034
map2k4amitogen-activated protein kinase kinase 4a0.034
lama1laminin, alpha 10.034
nortnotch-regulated transcript0.034
tpm1tropomyosin 1 (alpha)0.034
dlg2discs, large (Drosophila) homolog 20.034
slc24a5solute carrier family 24, member 50.033
pdgfrb2platelet derived growth factor receptor beta 20.033
bonbonnie and clyde0.033
nadl1.1neural adhesion molecule L1.10.033
prkcbbprotein kinase C, beta b0.033
shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.033
b3galt2UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 20.032
impdh1ainosine 5'-phosphate dehydrogenase 1a0.032
si:dkey-246k9.1si:dkey-246k9.10.032
si:dkeyp-84f11.5si:dkeyp-84f11.50.031
grk7aG-protein-coupled receptor kinase 7a0.030
flot1flotillin 10.030
si:dkey-69h6.7si:dkey-69h6.70.030
prkcdprotein kinase C, delta0.030
zgc:85939zgc:859390.029
zgc:114199zgc:1141990.029
zgc:153148zgc:1531480.029
zgc:112079zgc:1120790.028
vclvinculin0.028
tsc1atuberous sclerosis 1a0.028
uevldUEV and lactate/malate dehyrogenase domains0.028
clyblcitrate lyase beta-like0.027
zyg11zyg-11 homolog (C. elegans)0.027
csadcysteine sulfinic acid decarboxylase0.027
rhpn2rhophilin, Rho GTPase binding protein 20.027
ripk2receptor-interacting serine-threonine kinase 20.027
tmf1TATA element modulatory factor 10.027
dpp7dipeptidyl-peptidase 70.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
grhgrainy head0.064
sdtstardust0.024
mmymummy0.018
rokRho-kinase0.015
kkvkrotzkopf verkehrt0.012
bunbunched0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gdnfglial cell line derived neurotrophic factor0.929
Pax2paired box gene 20.917
Fgf8fibroblast growth factor 80.762
Wnt4wingless-related MMTV integration site 40.720
Gli3GLI-Kruppel family member GLI30.442
Tbrachyury0.438
Dkk1dickkopf homolog 1 (Xenopus laevis)0.434
Wnt3awingless-related MMTV integration site 3A0.415
Lmx1bLIM homeobox transcription factor 1 beta0.311
Lhx1LIM homeobox protein 10.281
Fgf18fibroblast growth factor 180.277
Pax8paired box gene 80.269
Wnt6wingless-related MMTV integration site 60.265
Hoxa13homeobox A130.176
Pou3f3POU domain, class 3, transcription factor 30.168
Hmx3H6 homeobox 30.166
Shhsonic hedgehog0.161
Ror2receptor tyrosine kinase-like orphan receptor 20.154
Wnt10bwingless related MMTV integration site 10b0.142
Klklotho0.120
Twist2twist homolog 2 (Drosophila)0.117
Foxn1forkhead box N10.116
Gli1GLI-Kruppel family member GLI10.116
Wnt2bwingless related MMTV integration site 2b0.110
Ephb2Eph receptor B20.109
Clic3chloride intracellular channel 30.100
Emid2EMI domain containing 20.094
Kcnh3potassium voltage-gated channel, subfamily H (eag-related), member 30.094
Bmp7bone morphogenetic protein 70.093
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.092
Hoxa11homeobox A110.087
Sim2single-minded homolog 2 (Drosophila)0.083
Hoxd13homeobox D130.083
Lmx1aLIM homeobox transcription factor 1 alpha0.081
Pcsk5proprotein convertase subtilisin/kexin type 50.081
Emx2empty spiracles homolog 2 (Drosophila)0.080
Pou3f1POU domain, class 3, transcription factor 10.079
Barx1BarH-like homeobox 10.079
Gli2GLI-Kruppel family member GLI20.079
Cd151CD151 antigen0.077
Col13a1collagen, type XIII, alpha 10.076
Amhr2anti-Mullerian hormone type 2 receptor0.075
Btbd17BTB (POZ) domain containing 170.074
Efna4ephrin A40.072
Fzd10frizzled homolog 10 (Drosophila)0.071
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.070
Acanaggrecan0.070
Foxd2forkhead box D20.069
Tbx2T-box 20.069
Hoxd9homeobox D90.067
Pitx1paired-like homeodomain transcription factor 10.067
Emx1empty spiracles homolog 1 (Drosophila)0.066
Pitx3paired-like homeodomain transcription factor 30.063
Wnt9awingless-type MMTV integration site 9A0.062
Ptpn14protein tyrosine phosphatase, non-receptor type 140.061
Tead3TEA domain family member 30.061
Hoxd11homeobox D110.061
3110079O15RikRIKEN cDNA 3110079O15 gene0.060
Bnc1basonuclin 10.060
Foxf1aforkhead box F1a0.059
Col22a1collagen, type XXII, alpha 10.058
Barx2BarH-like homeobox 20.058
Trp73transformation related protein 730.058
Neurog1neurogenin 10.058
Vstm2bV-set and transmembrane domain containing 2B0.057
Zbtb7czinc finger and BTB domain containing 7C0.057
UncxUNC homeobox0.056
Nognoggin0.055
Npas1neuronal PAS domain protein 10.055
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.054
Hoxa10homeobox A100.054
Hoxc9homeobox C90.053
Adra2badrenergic receptor, alpha 2b0.052
Foxn4forkhead box N40.050
Alx4aristaless-like homeobox 40.050
Tcfap2ctranscription factor AP-2, gamma0.050
Rargretinoic acid receptor, gamma0.049
Hsd11b2hydroxysteroid 11-beta dehydrogenase 20.049
Otx1orthodenticle homolog 1 (Drosophila)0.049
Tctex1d4Tctex1 domain containing 40.048
Efna2ephrin A20.048
Tgfatransforming growth factor alpha0.047
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.046
Pkn2protein kinase N20.045
Amhanti-Mullerian hormone0.045
Col4a3collagen, type IV, alpha 30.045
Foxb1forkhead box B10.044
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.043
Sox9SRY-box containing gene 90.043
BC024139cDNA sequence BC0241390.042
BikBCL2-interacting killer0.042
Irs1insulin receptor substrate 10.042
Nkx6-1NK6 homeobox 10.042
Fgf15fibroblast growth factor 150.041
Dlx4distal-less homeobox 40.041
Zfp651zinc finger protein 6510.041
Epha1Eph receptor A10.041
Usp9xubiquitin specific peptidase 9, X chromosome0.040
Fzd8frizzled homolog 8 (Drosophila)0.040
Sox3SRY-box containing gene 30.039
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism