IMP
Process View
The network for 'negative regulation of striated muscle contraction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of striated muscle contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.
| Name | Description | Probability | Func Analog Organism |
|---|
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| HDAC6 | histone deacetylase 6 | 1.000 | |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.994 | |
| PDE6G | phosphodiesterase 6G, cGMP-specific, rod, gamma | 0.164 | |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 0.139 | |
| PRKCA | protein kinase C, alpha | 0.116 | |
| ATP13A2 | ATPase type 13A2 | 0.112 | |
| KCNIP3 | Kv channel interacting protein 3, calsenilin | 0.103 | |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 | 0.068 | |
| MIIP | migration and invasion inhibitory protein | 0.060 | |
| CANX | calnexin | 0.059 | |
| ADORA2A | adenosine A2a receptor | 0.058 | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.044 | |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.042 | |
| LDB3 | LIM domain binding 3 | 0.036 | |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.032 | |
| HDAC11 | histone deacetylase 11 | 0.032 | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.029 | |
| HTT | huntingtin | 0.028 | |
| SIRT2 | sirtuin 2 | 0.026 | |
| SH3BP1 | SH3-domain binding protein 1 | 0.023 | |
| PYGM | phosphorylase, glycogen, muscle | 0.022 | |
| ZMYM3 | zinc finger, MYM-type 3 | 0.020 | |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.020 | |
| TAZ | tafazzin | 0.020 | |
| HMOX2 | heme oxygenase (decycling) 2 | 0.019 | |
| G6PD | glucose-6-phosphate dehydrogenase | 0.019 | |
| ADRBK2 | adrenergic, beta, receptor kinase 2 | 0.019 | |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant | 0.018 | |
| CTTN | cortactin | 0.017 | |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.017 | |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.017 | |
| ACTN3 | actinin, alpha 3 | 0.015 | |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.015 | |
| POLH | polymerase (DNA directed), eta | 0.015 | |
| CSK | c-src tyrosine kinase | 0.015 | |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.015 | |
| GMIP | GEM interacting protein | 0.015 | |
| ARHGAP4 | Rho GTPase activating protein 4 | 0.014 | |
| TNNC1 | troponin C type 1 (slow) | 0.013 | |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.013 | |
| TNNT3 | troponin T type 3 (skeletal, fast) | 0.013 | |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.013 | |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | 0.013 | |
| EGF | epidermal growth factor | 0.013 | |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.012 | |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.012 | |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta | 0.012 | |
| PRSS23 | protease, serine, 23 | 0.012 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.012 | |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.011 | |
| TRABD | TraB domain containing | 0.011 | |
| EIF1 | eukaryotic translation initiation factor 1 | 0.011 | |
| LPAR2 | lysophosphatidic acid receptor 2 | 0.011 | |
| TNNC2 | troponin C type 2 (fast) | 0.011 | |
| NBEAL2 | neurobeachin-like 2 | 0.011 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.010 | |
| RGS14 | regulator of G-protein signaling 14 | 0.010 | |
| ATF2 | activating transcription factor 2 | 0.010 |
Loading network...
Rattus norvegicus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cdc42bpb | CDC42 binding protein kinase beta (DMPK-like) | 0.059 | |
| Ank2 | ankyrin 2, neuronal | 0.050 | |
| Pctk1 | PCTAIRE protein kinase 1 | 0.045 | |
| Pfkfb4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.037 | |
| Adora1 | adenosine A1 receptor | 0.027 | |
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.025 | |
| Gzmb | granzyme B | 0.022 | |
| Strn | striatin, calmodulin binding protein | 0.022 | |
| Git1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.021 | |
| Trim28 | tripartite motif-containing 28 | 0.020 | |
| Atxn3 | ataxin 3 | 0.019 | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.019 | |
| Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.018 | |
| Il8rb | interleukin 8 receptor, beta | 0.018 | |
| Pemt | phosphatidylethanolamine N-methyltransferase | 0.017 | |
| Cx3cr1 | chemokine (C-X3-C motif) receptor 1 | 0.017 | |
| Sparcl1 | SPARC-like 1 (hevin) | 0.017 | |
| Camta2 | calmodulin binding transcription activator 2 | 0.016 | |
| Slc1a3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.014 | |
| Tfec | transcription factor EC | 0.014 | |
| Smad3 | SMAD family member 3 | 0.013 | |
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.012 | |
| Ptms | parathymosin | 0.012 | |
| Aqp4 | aquaporin 4 | 0.012 | |
| Shox2 | short stature homeobox 2 | 0.012 | |
| Mbp | myelin basic protein | 0.012 | |
| Olig1 | oligodendrocyte transcription factor 1 | 0.011 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.011 | |
| Ptafr | platelet-activating factor receptor | 0.011 | |
| Sfrp4 | secreted frizzled-related protein 4 | 0.011 |