The network for 'positive regulation of tyrosine phosphorylation of stat protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of tyrosine phosphorylation of stat protein

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

NameDescriptionProbabilityFunc Analog Organism
mpxmyeloid-specific peroxidase0.510
prox1prospero-related homeobox gene 10.452
il6stinterleukin 6 signal transducer0.199
cmybtranscription factor cmyb0.159
csf1racolony stimulating factor 1 receptor, a0.146
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.128
otpborthopedia homolog b0.066
pmelapremelanosome protein a0.053
mitfamicrophthalmia-associated transcription factor a0.050
cbfbcore-binding factor, beta subunit0.047
pax7bpaired box gene 7b0.047
tnfrsf18tumor necrosis factor receptor superfamily, member 180.046
insm1ainsulinoma-associated 1a0.041
actc1bactin, alpha, cardiac muscle 1b0.040
scn1bbsodium channel, voltage-gated, type I, beta b0.037
trpm7transient receptor potential cation channel, subfamily M, member 70.035
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.033
her15.1hairy and enhancer of split-related 15.10.033
cdh6cadherin 60.031
scrt2scratch homolog 2, zinc finger protein (Drosophila)0.031
dmrt2adoublesex and mab-3 related transcription factor 2a0.031
il7rinterleukin 7 receptor0.031
ltkleukocyte tyrosine kinase0.030
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.029
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.029
gria1aglutamate receptor, ionotropic, AMPA 1a0.029
il6rinterleukin 6 receptor0.029
sema6dlsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like0.027
ndel1anudE nuclear distribution gene E homolog like 1 (A. nidulans) A0.027
oprd1bopioid receptor, delta 1b0.026
slc4a1bsolute carrier family 4, anion exchanger, member 1b0.026
insm1binsulinoma-associated 1b0.026
lmx1b.1LIM homeobox transcription factor 1, beta 10.025
six1bsine oculis homeobox homolog 1b0.025
cav1caveolin 10.025
mecomMDS1 and EVI1 complex locus0.024
nr2f6bnuclear receptor subfamily 2, group F, member 6b0.023
pcdh17protocadherin 170.023
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.023
zbtb10zinc finger and BTB domain containing 100.023
il4rinterleukin 4 receptor0.023
mapk15mitogen-activated protein kinase 150.023
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.022
tlr3toll-like receptor 30.022
runx3runt-related transcription factor 30.021
socs1suppressor of cytokine signaling 10.021
lin28alin-28 homolog A (C. elegans)0.020
s100tS100 calcium binding protein T0.020
socs3asuppressor of cytokine signaling 3a0.020
adcyap1r1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I0.020
kitlgakit ligand a0.020
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.019
stat3signal transduction and activation of transcription 30.019
ahcyl2S-adenosylhomocysteine hydrolase-like 20.019
fgf19fibroblast growth factor 190.019
s1pr2sphingosine-1-phosphate receptor 20.018
zswim5zinc finger, SWIM-type containing 50.017
chrna6cholinergic receptor, nicotinic, alpha 60.017
cyyr1cysteine and tyrosine-rich protein 10.017
aox3aldehyde oxidase 30.017
ctbp2lC-terminal binding protein 2, like0.017
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.016
kitakit receptor a0.016
emx3empty spiracles homeobox 30.016
tnfrsfatumor necrosis factor receptor superfamily, member a0.016
foxj1aforkhead box J1a0.016
ifi35interferon-induced protein 350.015
dnm2dynamin 20.015
cd247lCD247 antigen like0.014
mesp2mesoderm posterior 2 homolog (mouse)0.014
ccr12.2chemokine (C-C motif) receptor 12.20.014
hoxb5ahomeo box B5a0.014
abl1c-abl oncogene 1, non-receptor tyrosine kinase0.014
cpa5carboxypeptidase A50.014
iclp1invariant chain-like protein 10.014
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto0.014
tnfsf10l2tumor necrosis factor (ligand) superfamily, member 10 like 20.014
radilRap GTPase interactor0.014
cadm1acell adhesion molecule 1a0.014
dlx5adistal-less homeobox gene 5a0.013
elovl4aelongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a0.013
traf4atnf receptor-associated factor 4a0.013
LOC567405novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)0.013
gfi1.1growth factor independent 1.10.013
nlgn2bneuroligin 2b0.013
ptk6aPTK6 protein tyrosine kinase 6a0.013
cd247CD247 antigen0.013
irf3interferon regulatory factor 30.013
LOC553366hypothetical protein LOC5533660.013
wnk1WNK lysine deficient protein kinase 10.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
SOCS3suppressor of cytokine signaling 30.993
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.989
CASP10caspase 10, apoptosis-related cysteine peptidase0.970
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.955
IL6interleukin 6 (interferon, beta 2)0.946
TRAF1TNF receptor-associated factor 10.929
IL4Rinterleukin 4 receptor0.924
JAK2Janus kinase 20.896
FGF1fibroblast growth factor 1 (acidic)0.850
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.824
CCR5chemokine (C-C motif) receptor 50.816
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.761
TRADDTNFRSF1A-associated via death domain0.747
IGF1Rinsulin-like growth factor 1 receptor0.735
CCL4chemokine (C-C motif) ligand 40.717
TNFtumor necrosis factor0.706
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.706
CASP8caspase 8, apoptosis-related cysteine peptidase0.704
GH1growth hormone 10.679
SHC1SHC (Src homology 2 domain containing) transforming protein 10.668
NR4A1nuclear receptor subfamily 4, group A, member 10.664
ICAM1intercellular adhesion molecule 10.654
CXCL9chemokine (C-X-C motif) ligand 90.639
FADDFas (TNFRSF6)-associated via death domain0.639
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.626
VEGFAvascular endothelial growth factor A0.607
TRAF5TNF receptor-associated factor 50.550
SYKspleen tyrosine kinase0.547
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.539
CCL8chemokine (C-C motif) ligand 80.467
IL23Ainterleukin 23, alpha subunit p190.463
GRB2growth factor receptor-bound protein 20.463
CCL2chemokine (C-C motif) ligand 20.461
GAB1GRB2-associated binding protein 10.459
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.448
PTPN11protein tyrosine phosphatase, non-receptor type 110.438
CXCL2chemokine (C-X-C motif) ligand 20.409
PLCG1phospholipase C, gamma 10.394
IL1Binterleukin 1, beta0.394
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.357
IL8interleukin 80.343
TNFSF10tumor necrosis factor (ligand) superfamily, member 100.315
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.312
CSH2chorionic somatomammotropin hormone 20.300
CCL7chemokine (C-C motif) ligand 70.291
HDAC2histone deacetylase 20.276
TRAF2TNF receptor-associated factor 20.265
EPORerythropoietin receptor0.263
CFLARCASP8 and FADD-like apoptosis regulator0.262
IL10interleukin 100.253
STAT4signal transducer and activator of transcription 40.248
INSRinsulin receptor0.240
LATlinker for activation of T cells0.224
JAK1Janus kinase 10.210
CDH5cadherin 5, type 2 (vascular endothelium)0.207
SOCS1suppressor of cytokine signaling 10.201
CXCL10chemokine (C-X-C motif) ligand 100.195
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.185
NRP1neuropilin 10.184
CCL5chemokine (C-C motif) ligand 50.182
CAV1caveolin 1, caveolae protein, 22kDa0.181
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.180
CSHL1chorionic somatomammotropin hormone-like 10.177
CXCL3chemokine (C-X-C motif) ligand 30.170
IL2RGinterleukin 2 receptor, gamma0.168
GAB2GRB2-associated binding protein 20.166
GH2growth hormone 20.166
IGF2Rinsulin-like growth factor 2 receptor0.164
CCL13chemokine (C-C motif) ligand 130.148
IRS1insulin receptor substrate 10.139
CCL11chemokine (C-C motif) ligand 110.137
CCR7chemokine (C-C motif) receptor 70.136
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.134
SLAMF1signaling lymphocytic activation molecule family member 10.133
CSF1colony stimulating factor 1 (macrophage)0.126
IL12Ainterleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)0.115
WIPF1WAS/WASL interacting protein family, member 10.114
GHRgrowth hormone receptor0.110
CXCL13chemokine (C-X-C motif) ligand 130.109
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.105
SELEselectin E0.101
IDEinsulin-degrading enzyme0.094
STAT5Asignal transducer and activator of transcription 5A0.090
FGFR1fibroblast growth factor receptor 10.089
CCR1chemokine (C-C motif) receptor 10.088
CCL3chemokine (C-C motif) ligand 30.084
PGFplacental growth factor0.084
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.083
VCAM1vascular cell adhesion molecule 10.083
CXCL11chemokine (C-X-C motif) ligand 110.082
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.081
CXCL5chemokine (C-X-C motif) ligand 50.081
APPamyloid beta (A4) precursor protein0.078
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.076
CD40CD40 molecule, TNF receptor superfamily member 50.075
UBASH3Bubiquitin associated and SH3 domain containing B0.072
CCL22chemokine (C-C motif) ligand 220.070
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ikzf1IKAROS family zinc finger 10.946
Emx1empty spiracles homolog 1 (Drosophila)0.840
Rag1recombination activating gene 10.821
Ifnginterferon gamma0.819
Tnftumor necrosis factor0.815
Csf1colony stimulating factor 1 (macrophage)0.731
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.647
Inpp5dinositol polyphosphate-5-phosphatase D0.585
Il10interleukin 100.504
Ptpn11protein tyrosine phosphatase, non-receptor type 110.469
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.450
Emx2empty spiracles homolog 2 (Drosophila)0.400
Col1a1collagen, type I, alpha 10.399
Vegfavascular endothelial growth factor A0.395
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.347
Il2rginterleukin 2 receptor, gamma chain0.345
Stat3signal transducer and activator of transcription 30.332
Fgf8fibroblast growth factor 80.321
Lyz2lysozyme 20.302
Nos3nitric oxide synthase 3, endothelial cell0.245
FasFas (TNF receptor superfamily member 6)0.244
Tgfb1transforming growth factor, beta 10.229
Nos2nitric oxide synthase 2, inducible0.228
Cd19CD19 antigen0.222
Prf1perforin 1 (pore forming protein)0.215
Ptprcprotein tyrosine phosphatase, receptor type, C0.193
Lhx3LIM homeobox protein 30.168
CblCasitas B-lineage lymphoma0.167
Pax2paired box gene 20.164
Ptenphosphatase and tensin homolog0.157
TcraT-cell receptor alpha chain0.145
Otx2orthodenticle homolog 2 (Drosophila)0.143
Mmp9matrix metallopeptidase 90.138
Tgfbr2transforming growth factor, beta receptor II0.128
Esr1estrogen receptor 1 (alpha)0.123
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.108
Gli3GLI-Kruppel family member GLI30.101
Itgb1integrin beta 1 (fibronectin receptor beta)0.089
Kitkit oncogene0.087
Nr5a1nuclear receptor subfamily 5, group A, member 10.083
Foxc2forkhead box C20.079
Foxn1forkhead box N10.076
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.075
Retret proto-oncogene0.074
Pitx2paired-like homeodomain transcription factor 20.071
Stat6signal transducer and activator of transcription 60.065
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.065
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.064
Trp53transformation related protein 530.061
Foxh1forkhead box H10.059
Foxp3forkhead box P30.059
Sox2SRY-box containing gene 20.058
Cdkn1bcyclin-dependent kinase inhibitor 1B0.055
Myd88myeloid differentiation primary response gene 880.053
Jag1jagged 10.051
Foxc1forkhead box C10.051
Leprleptin receptor0.049
Map3k14mitogen-activated protein kinase kinase kinase 140.048
Jak2Janus kinase 20.047
Pax6paired box gene 60.047
Gdnfglial cell line derived neurotrophic factor0.046
Cd44CD44 antigen0.042
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.040
Fgd1FYVE, RhoGEF and PH domain containing 10.037
Tlr4toll-like receptor 40.036
Ctnnb1catenin (cadherin associated protein), beta 10.036
Lcklymphocyte protein tyrosine kinase0.035
Pax3paired box gene 30.034
Gbx2gastrulation brain homeobox 20.034
Chd7chromodomain helicase DNA binding protein 70.033
Grb2growth factor receptor bound protein 20.032
Il2rbinterleukin 2 receptor, beta chain0.032
Adam17a disintegrin and metallopeptidase domain 170.032
Otx1orthodenticle homolog 1 (Drosophila)0.031
Hes5hairy and enhancer of split 5 (Drosophila)0.030
Nrg1neuregulin 10.030
Fgfr1fibroblast growth factor receptor 10.029
Il2interleukin 20.029
Foxg1forkhead box G10.029
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.029
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.029
Sox10SRY-box containing gene 100.028
Ccl2chemokine (C-C motif) ligand 20.028
Ighimmunoglobulin heavy chain complex0.027
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.027
FybFYN binding protein0.027
Eya1eyes absent 1 homolog (Drosophila)0.027
Il27rainterleukin 27 receptor, alpha0.026
Fcgr2bFc receptor, IgG, low affinity IIb0.026
Isl1ISL1 transcription factor, LIM/homeodomain0.025
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.025
Latlinker for activation of T cells0.025
Cdh5cadherin 50.024
Cd40CD40 antigen0.024
Lifleukemia inhibitory factor0.023
Cd247CD247 antigen0.023
Gata4GATA binding protein 40.023
Itgb2integrin beta 20.023
Socs1suppressor of cytokine signaling 10.023
Irf1interferon regulatory factor 10.022
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism