The network for 'extracellular matrix assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

extracellular matrix assembly

The aggregation, arrangement and bonding together of the extracellular matrix.

NameDescriptionProbabilityFunc Analog Organism
ptch1patched 10.659
ptch2patched 20.613
lamb1alaminin, beta 1a0.122
prdm5PR domain containing 50.096
col2a1acollagen type II, alpha-1a0.075
tbx24T-box 240.074
furinafurin (paired basic amino acid cleaving enzyme) a0.073
pdlim4PDZ and LIM domain 40.071
itgb3bintegrin beta 3b0.065
ntd5ntl-dependent gene 50.064
bmp1abone morphogenetic protein 1a0.061
tbx20T-box 200.060
fam20bfamily with sequence similarity 20, member B (H. sapiens)0.051
bmp2abone morphogenetic protein 2a0.049
igf1rbinsulin-like growth factor 1b receptor0.048
pax7apaired box gene 7a0.045
tfe3atranscription factor binding to IGHM enhancer 3a0.042
fabp6fatty acid binding protein 6, ileal (gastrotropin)0.041
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.040
fn1fibronectin 10.039
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.038
vsx2visual system homeobox 20.037
chatcholine acetyltransferase0.036
tll1tolloid-like 10.034
spon2aspondin 2a, extracellular matrix protein0.033
plp1aproteolipid protein 1a0.033
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.031
rad21RAD21 homolog (S. pombe)0.030
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.029
mpllmyeloproliferative leukemia virus oncogene, like0.029
mgpmatrix Gla protein0.028
tcf7transcription factor 7 (T-cell specific, HMG-box)0.027
sh3gl1bSH3-domain GRB2-like 1b0.027
ptpraprotein tyrosine phosphatase, receptor type, A0.026
her7hairy and enhancer of split related-70.026
alpialkaline phosphatase, intestinal0.026
chrm2acholinergic receptor, muscarinic 2a0.025
rnasel1ribonuclease like 10.025
rag1recombination activating gene 10.025
vtg3vitellogenin 3, phosvitinless0.023
notch3notch homolog 30.023
tuba8l3tubulin, alpha 8 like 30.023
alpalkaline phosphatase0.022
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.022
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.022
fabp2fatty acid binding protein 2, intestinal0.022
mbpmyelin basic protein0.021
mfn2mitofusin 20.021
xylt1xylosyltransferase 10.021
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.021
oprm1opioid receptor, mu 10.021
plp1bproteolipid protein 1b0.020
lppLIM domain containing preferred translocation partner in lipoma0.020
crb2acrumbs homolog 2a0.020
hmcn1hemicentin 10.020
trpm7transient receptor potential cation channel, subfamily M, member 70.020
ca8carbonic anhydrase VIII0.019
wif1wnt inhibitory factor 10.019
mibmind bomb0.019
smad3bMAD, mothers against decapentaplegic homolog 3b (Drosophila)0.019
mpzmyelin protein zero0.019
bmp6bone morphogenetic protein 60.019
terttelomerase reverse transcriptase0.019
ptprfprotein tyrosine phosphatase, receptor type, F0.019
rspo1R-spondin homolog (Xenopus laevis)0.019
prkczprotein kinase C, zeta0.019
sesn1sestrin 10.019
hgdhomogentisate 1,2-dioxygenase0.019
tbx18T-box 180.018
sox9bSRY-box containing gene 9b0.018
dnmt6DNA (cytosine-5-)-methyltransferase 60.018
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.018
hnf1aHNF1 homeobox a0.018
ntrk2bneurotrophic tyrosine kinase, receptor, type 2b0.018
gpr126G protein-coupled receptor 1260.018
gle1GLE1 RNA export mediator homolog (yeast)0.018
bambibBMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b0.017
dag1dystroglycan 10.017
LOC100537340cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like0.017
myhc4myosin heavy chain 40.017
fasFas (TNF receptor superfamily, member 6)0.017
cnr1cannabinoid receptor 10.017
pcsk5bproprotein convertase subtilisin/kexin type 5b0.017
smad9MAD homolog 9 (Drosophila)0.017
fgf4fibroblast growth factor 40.017
nav3neuron navigator 30.017
ikzf1IKAROS family zinc finger 1 (Ikaros)0.017
timp2atissue inhibitor of metalloproteinase 2a0.017
ptgs1prostaglandin-endoperoxide synthase 10.017
igf2ainsulin-like growth factor 2a0.017
gdf6agrowth differentiation factor 6a0.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Vm26AbVitelline membrane 26Ab0.894
dec-1defective chorion 10.853
fs(1)Nfemale sterile (1) Nasrat0.822
EgfrEpidermal growth factor receptor0.652
Vm26AaVitelline membrane 26Aa0.226
fs(1)M3female sterile (1) M30.217
CG11505CG11505 gene product from transcript CG11505-RA0.195
FemcoatCG15573 gene product from transcript CG15573-RB0.160
Vm34CaVitelline membrane 34Ca0.138
LamCLamin C0.136
Cp36Chorion protein 360.109
Cg25CCollagen type IV0.091
CG13550CG13550 gene product from transcript CG13550-RA0.084
Cad99CCG31009 gene product from transcript CG31009-RB0.057
MESR4Misexpression suppressor of ras 40.055
Yp2Yolk protein 20.049
CG3457CG3457 gene product from transcript CG3457-RA0.041
ash1absent, small, or homeotic discs 10.040
CG14303CG14303 gene product from transcript CG14303-RA0.039
BicCBicaudal C0.035
Yp3Yolk protein 30.035
CycJCyclin J0.033
CG12398CG12398 gene product from transcript CG12398-RA0.032
mewmultiple edematous wings0.030
eveeven skipped0.026
Mef2Myocyte enhancer factor 20.026
CG13992CG13992 gene product from transcript CG13992-RB0.025
l(2)05510lethal (2) 055100.024
SpxSpliceosomal protein on the X0.022
Su(var)3-7Suppressor of variegation 3-70.022
CG13998CG13998 gene product from transcript CG13998-RA0.021
spz5spatzle 50.018
wbwing blister0.017
Cp38Chorion protein 380.017
dltdiscs lost0.016
Prat2Phosphoribosylamidotransferase 20.015
cicubitus interruptus0.015
Ranbp11CG33139 gene product from transcript CG33139-RA0.014
Cp15Chorion protein 150.014
Fcp3CFollicle cell protein 3C0.014
CG6927CG6927 gene product from transcript CG6927-RA0.014
myoglianinCG1838 gene product from transcript CG1838-RD0.014
CG8709CG8709 gene product from transcript CG8709-RK0.013
GABA-B-R2metabotropic GABA-B receptor subtype 20.013
CG5669CG5669 gene product from transcript CG5669-RA0.013
Nup160Nucleoporin 1600.013
CG4020CG4020 gene product from transcript CG4020-RA0.013
sosine oculis0.013
hdhumpty dumpty0.012
trpmltransient receptor potential mucolipin0.012
Cp7FbChorion protein b at 7F0.012
CG13042CG13042 gene product from transcript CG13042-RA0.012
APP-BP1beta-Amyloid precursor protein binding protein 10.012
CG11674CG11674 gene product from transcript CG11674-RA0.012
enokenoki mushroom0.012
Vm32EVitelline membrane 32E0.011
CG5278CG5278 gene product from transcript CG5278-RA0.011
Bre1CG10542 gene product from transcript CG10542-RA0.011
Cpr12ACuticular protein 12A0.011
Muc4BMucin 4B0.011
CG32834CG32834 gene product from transcript CG32834-RB0.011
MED24Mediator complex subunit 240.011
Pde8Phosphodiesterase 80.010
YT521-BCG12076 gene product from transcript CG12076-RB0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FBN1fibrillin 10.131
TEKTEK tyrosine kinase, endothelial0.103
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.054
FLNAfilamin A, alpha0.030
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.027
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.019
FN1fibronectin 10.018
FBLN1fibulin 10.018
CTGFconnective tissue growth factor0.014
LTBP2latent transforming growth factor beta binding protein 20.013
FGAfibrinogen alpha chain0.012
LAMB1laminin, beta 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fbn1fibrillin 10.882
Pax3paired box gene 30.699
Gli3GLI-Kruppel family member GLI30.345
Hspg2perlecan (heparan sulfate proteoglycan 2)0.314
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.220
Notch3Notch gene homolog 3 (Drosophila)0.194
Tgfb1i1transforming growth factor beta 1 induced transcript 10.164
Ltbp4latent transforming growth factor beta binding protein 40.149
Gli2GLI-Kruppel family member GLI20.136
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.132
Nid1nidogen 10.108
Lama5laminin, alpha 50.107
Fgfr1fibroblast growth factor receptor 10.104
Loxlysyl oxidase0.103
Ror2receptor tyrosine kinase-like orphan receptor 20.102
Col2a1collagen, type II, alpha 10.086
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.082
Tenc1tensin like C1 domain-containing phosphatase0.079
Col6a2collagen, type VI, alpha 20.075
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.073
Col11a1collagen, type XI, alpha 10.066
Egfl7EGF-like domain 70.065
Fgfr2fibroblast growth factor receptor 20.064
Ltbp2latent transforming growth factor beta binding protein 20.061
Foxc1forkhead box C10.054
Tgfbr2transforming growth factor, beta receptor II0.052
Loxl1lysyl oxidase-like 10.051
Dll4delta-like 4 (Drosophila)0.048
Npr2natriuretic peptide receptor 20.047
Lamb1laminin B10.047
Col1a1collagen, type I, alpha 10.047
Fgf8fibroblast growth factor 80.047
Tcfap2atranscription factor AP-2, alpha0.046
Lamb2laminin, beta 20.045
Pcsk5proprotein convertase subtilisin/kexin type 50.044
Mfap4microfibrillar-associated protein 40.043
Smosmoothened homolog (Drosophila)0.043
Col6a1collagen, type VI, alpha 10.040
Fbln2fibulin 20.040
Vegfavascular endothelial growth factor A0.039
Pkd1polycystic kidney disease 1 homolog0.035
Hes1hairy and enhancer of split 1 (Drosophila)0.035
Fgfr3fibroblast growth factor receptor 30.034
Mrc2mannose receptor, C type 20.032
Sod3superoxide dismutase 3, extracellular0.031
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.029
Sox11SRY-box containing gene 110.028
Col8a1collagen, type VIII, alpha 10.028
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.027
Mmp2matrix metallopeptidase 20.026
Atoh7atonal homolog 7 (Drosophila)0.025
Adcy4adenylate cyclase 40.024
Pthlhparathyroid hormone-like peptide0.023
Gata4GATA binding protein 40.023
Nf1neurofibromatosis 10.023
Npr3natriuretic peptide receptor 30.022
Phldb1pleckstrin homology-like domain, family B, member 10.022
Sorbs3sorbin and SH3 domain containing 30.022
Angptl2angiopoietin-like 20.022
Shesrc homology 2 domain-containing transforming protein E0.022
Col4a2collagen, type IV, alpha 20.022
Col6a3collagen, type VI, alpha 30.021
Fbln5fibulin 50.021
Bnc1basonuclin 10.020
Col4a1collagen, type IV, alpha 10.020
Bmp4bone morphogenetic protein 40.020
Gas1growth arrest specific 10.020
Lama2laminin, alpha 20.020
Trp63transformation related protein 630.020
Adamts2a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20.019
Notch1Notch gene homolog 1 (Drosophila)0.019
Pdgfbplatelet derived growth factor, B polypeptide0.019
Mcammelanoma cell adhesion molecule0.019
Cachd1cache domain containing 10.019
Fbn2fibrillin 20.018
Alx4aristaless-like homeobox 40.018
Jag1jagged 10.018
Prelpproline arginine-rich end leucine-rich repeat0.018
Fzd2frizzled homolog 2 (Drosophila)0.018
Htra3HtrA serine peptidase 30.018
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.017
Wfikkn1WAP, FS, Ig, KU, and NTR-containing protein 10.017
Sox9SRY-box containing gene 90.017
Pax6paired box gene 60.017
Nbl1neuroblastoma, suppression of tumorigenicity 10.017
Aoc3amine oxidase, copper containing 30.017
Igfbp5insulin-like growth factor binding protein 50.017
Scarf2scavenger receptor class F, member 20.016
Steap3STEAP family member 30.016
Ltbp1latent transforming growth factor beta binding protein 10.016
Igfbp6insulin-like growth factor binding protein 60.016
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.016
Dll1delta-like 1 (Drosophila)0.015
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.015
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism