The network for 'embryonic organ development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic organ development

Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 11.000
mibmind bomb1.000
cdh2cadherin 2, neuronal1.000
shhasonic hedgehog a1.000
fgf8afibroblast growth factor 8 a1.000
foxi1forkhead box I11.000
flhfloating head1.000
bmp2bbone morphogenetic protein 2b0.999
pax2apaired box gene 2a0.999
crabp2acellular retinoic acid binding protein 2, a0.999
prdm1aPR domain containing 1a, with ZNF domain0.999
lft2lefty20.999
dlx2adistal-less homeobox gene 2a0.998
bmp4bone morphogenetic protein 40.998
hand2heart and neural crest derivatives expressed transcript 20.998
tal1T-cell acute lymphocytic leukemia 10.998
gli2aGLI-Kruppel family member GLI2a0.998
fgf3fibroblast growth factor 30.997
tp53tumor protein p530.997
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.997
sox9aSRY-box containing gene 9a0.996
sox32SRY-box containing gene 320.995
kdrlkinase insert domain receptor like0.995
cdoncell adhesion molecule-related/down-regulated by oncogenes0.995
fn1fibronectin 10.995
gata3GATA-binding protein 30.995
isl1islet10.994
pkd2polycystic kidney disease 20.993
eya1eyes absent homolog 10.993
hnf1baHNF1 homeobox Ba0.993
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.992
tfap2atranscription factor AP-2 alpha0.992
lamb1alaminin, beta 1a0.992
aldh1a2aldehyde dehydrogenase 1 family, member A20.991
twist1atwist1a0.990
spawsouthpaw0.989
notch1anotch homolog 1a0.988
notch2notch homolog 20.988
edn1endothelin 10.987
lmx1b.1LIM homeobox transcription factor 1, beta 10.987
wnt11wingless-type MMTV integration site family, member 110.986
hoxa2bhomeo box A2b0.985
slit3slit (Drosophila) homolog 30.984
sox1aSRY-box containing gene 1a0.983
fras1Fraser syndrome 10.982
lef1lymphocyte enhancer binding factor 10.981
irx1airoquois homeobox protein 1, a0.981
dlx3bdistal-less homeobox gene 3b0.980
irx1biroquois homeobox protein 1, b0.979
myod1myogenic differentiation 10.978
notch3notch homolog 30.977
fbn2bfibrillin 2b0.976
tp63tumor protein p630.973
gdf6agrowth differentiation factor 6a0.973
hoxd4ahomeo box D4a0.973
six4bsine oculis homeobox homolog 4b0.973
jag1bjagged 1b0.973
shhbsonic hedgehog b0.970
ndr2nodal-related 20.963
tcf7transcription factor 7 (T-cell specific, HMG-box)0.962
pitx3paired-like homeodomain transcription factor 30.961
foxd3forkhead box D30.961
ptch1patched 10.959
pitx2paired-like homeodomain transcription factor 20.959
gata5GATA-binding protein 50.959
her6hairy-related 60.958
dlx5adistal-less homeobox gene 5a0.958
disp1dispatched homolog 1 (Drosophila)0.958
twist3twist30.957
atoh1aatonal homolog 1a0.953
hoxb5bhomeo box B5b0.952
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.951
znf703zinc finger protein 7030.948
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.948
pax6apaired box gene 6a0.946
hhexhematopoietically expressed homeobox0.946
hoxb3ahomeo box B3a0.945
fgfr4fibroblast growth factor receptor 40.944
runx2brunt-related transcription factor 2b0.943
dkk1bdickkopf 1b0.940
msxemuscle segment homeobox E0.937
hoxa3ahomeo box A3a0.936
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.935
mmp2matrix metalloproteinase 20.934
smad5MAD homolog 5 (Drosophila)0.933
sox2SRY-box containing gene 20.930
rgmaRGM domain family, member A0.927
tbx16T-box gene 160.925
sema3dsemaphorin 3d0.925
fgfr1afibroblast growth factor receptor 1a0.923
tbx18T-box 180.922
bmp2abone morphogenetic protein 2a0.921
otop1otopetrin 10.919
col5a2lcollagen, type V, alpha 2-like0.917
smosmoothened homolog (Drosophila)0.917
hapln1ahyaluronan and proteoglycan link protein 1a0.914
csadcysteine sulfinic acid decarboxylase0.912
ccnd1cyclin D10.912
wnt9awingless-type MMTV integration site family, member 9A0.912
col27a1acollagen, type XXVII, alpha 1a0.912
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-73Protein UNC-730.052
egl-18Protein EGL-180.038
trim-9Protein TRIM-90.026
pha-4Protein PHA-40.022
bar-1Protein BAR-10.020
hlh-1Protein HLH-10.018
egl-27Protein EGL-270.014
unc-53Protein UNC-530.014
lin-40Protein LIN-400.013
osm-5Protein OSM-50.013
glp-1Protein GLP-10.011
CELE_Y41E3.11Protein Y41E3.110.011
lin-17Protein LIN-170.011
ceh-32Protein CEH-320.011
mig-6Protein MIG-60.011
lev-1Protein LEV-10.011
hbl-1Protein HBL-10.011
cct-7Protein CCT-70.010
nhr-25Protein NHR-250.010
eor-2Protein EOR-20.010
pry-1Protein PRY-10.010
sma-6Protein SMA-60.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
wgwingless0.999
NNotch0.993
cicubitus interruptus0.988
dshdishevelled0.979
putpunt0.947
enengrailed0.930
zfh1Zn finger homeodomain 10.917
htlheartless0.917
Rac1CG2248 gene product from transcript CG2248-RA0.905
Fas2Fasciclin 20.905
tintinman0.900
crbcrumbs0.900
sdscalloped0.893
armarmadillo0.889
eyeyeless0.864
emcextra macrochaetae0.850
HandCG18144 gene product from transcript CG18144-RA0.798
EgfrEpidermal growth factor receptor0.779
LanB2Laminin B20.778
tkvthickveins0.776
nkdnaked cuticle0.771
Doc2Dorsocross20.749
MadMothers against dpp0.730
roboroundabout0.712
eyaeyes absent0.709
E(spl)Enhancer of split0.705
dppdecapentaplegic0.702
slp1sloppy paired 10.675
rapretina aberrant in pattern0.667
lealeak0.638
SerSerrate0.631
stumpsCG31317 gene product from transcript CG31317-RC0.580
spispitz0.580
fngfringe0.566
tshteashirt0.563
UbxUltrabithorax0.551
mewmultiple edematous wings0.550
atoatonal0.545
LanB1CG7123 gene product from transcript CG7123-RA0.520
sosine oculis0.481
LanALaminin A0.479
TlToll0.467
dacdachshund0.459
panpangolin0.454
domdomino0.454
DllDistal-less0.448
nmonemo0.441
ushu-shaped0.440
AntpAntennapedia0.437
zipzipper0.428
SmoxSmad on X0.427
Sra-1specifically Rac1-associated protein 10.427
Ptp69DProtein tyrosine phosphatase 69D0.422
dadaughterless0.398
phlpole hole0.388
opaodd paired0.383
bskbasket0.378
mammastermind0.369
shishibire0.364
araaraucan0.360
kniknirps0.353
dsdachsous0.352
exexpanded0.344
PvrPDGF- and VEGF-receptor related0.338
coscosta0.336
mirrmirror0.335
babobaboon0.327
HLHm7E(spl) region transcript m70.315
NetBNetrin-B0.313
dmdiminutive0.310
KrKruppel0.310
Su(var)2-10Suppressor of variegation 2-100.310
vgvestigial0.304
bibifid0.303
DfdDeformed0.296
linlines0.292
arrarrow0.289
LLobe0.282
midmidline0.274
eveeven skipped0.272
fjfour-jointed0.271
bazbazooka0.256
frcfringe connection0.247
TolloCG6890 gene product from transcript CG6890-RA0.246
gcmglial cells missing0.244
HLHmbetaE(spl) region transcript mbeta0.244
Akt1CG4006 gene product from transcript CG4006-RA0.243
OptixCG18455 gene product from transcript CG18455-RA0.236
mysmyospheroid0.233
ykiyorkie0.230
effeffete0.227
coracoracle0.226
Su(H)Suppressor of Hairless0.217
bab2CG9102 gene product from transcript CG9102-RA0.215
PtenCG5671 gene product from transcript CG5671-RB0.211
ttvtout-velu0.211
vvlventral veins lacking0.198
hbshibris0.198
Wnt4Wnt oncogene analog 40.188
fasfaint sausage0.186
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p530.998
SMAD3SMAD family member 30.990
CREBBPCREB binding protein0.989
EP300E1A binding protein p3000.987
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.957
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.924
SP1Sp1 transcription factor0.914
ESR1estrogen receptor 10.908
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.907
TAL1T-cell acute lymphocytic leukemia 10.896
MDM2Mdm2 p53 binding protein homolog (mouse)0.868
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.800
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.788
COL1A1collagen, type I, alpha 10.786
SMAD2SMAD family member 20.778
RB1retinoblastoma 10.723
ZFYVE9zinc finger, FYVE domain containing 90.697
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.697
NR4A1nuclear receptor subfamily 4, group A, member 10.686
JAG1jagged 10.681
NOTCH1notch 10.669
SIN3ASIN3 homolog A, transcription regulator (yeast)0.668
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.642
RXRAretinoid X receptor, alpha0.628
BMP2bone morphogenetic protein 20.565
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.563
SMAD4SMAD family member 40.553
NCOR1nuclear receptor corepressor 10.529
HOXB5homeobox B50.529
GSK3Bglycogen synthase kinase 3 beta0.529
SKILSKI-like oncogene0.517
TCF4transcription factor 40.515
EPAS1endothelial PAS domain protein 10.509
JUNjun proto-oncogene0.467
RBBP4retinoblastoma binding protein 40.460
RUNX1runt-related transcription factor 10.442
TCF12transcription factor 120.418
PMLpromyelocytic leukemia0.409
MMP14matrix metallopeptidase 14 (membrane-inserted)0.398
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.371
GATA4GATA binding protein 40.351
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.348
NCOA1nuclear receptor coactivator 10.341
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.329
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.312
NRP1neuropilin 10.293
PRKCZprotein kinase C, zeta0.287
FSTL1follistatin-like 10.277
COL2A1collagen, type II, alpha 10.276
MTA1metastasis associated 10.276
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.272
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.270
COL3A1collagen, type III, alpha 10.266
TNRC6Atrinucleotide repeat containing 6A0.255
ATF2activating transcription factor 20.254
VEGFAvascular endothelial growth factor A0.239
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.237
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.226
E2F7E2F transcription factor 70.221
CXCL3chemokine (C-X-C motif) ligand 30.211
DAXXdeath-domain associated protein0.210
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.209
APCadenomatous polyposis coli0.198
MTA3metastasis associated 1 family, member 30.194
HOXA11homeobox A110.194
LAMB1laminin, beta 10.194
PIAS1protein inhibitor of activated STAT, 10.192
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.191
SMAD1SMAD family member 10.188
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.182
HIPK2homeodomain interacting protein kinase 20.181
SKIv-ski sarcoma viral oncogene homolog (avian)0.178
COL4A1collagen, type IV, alpha 10.177
HDAC1histone deacetylase 10.177
ATXN1ataxin 10.175
CTGFconnective tissue growth factor0.171
MYOD1myogenic differentiation 10.170
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.163
HOXB6homeobox B60.155
HOXA5homeobox A50.154
ARNTaryl hydrocarbon receptor nuclear translocator0.150
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.150
E2F8E2F transcription factor 80.150
COL5A1collagen, type V, alpha 10.150
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.149
CALCAcalcitonin-related polypeptide alpha0.149
TP73tumor protein p730.148
HOXA10homeobox A100.144
KRT18keratin 180.139
WDR5WD repeat domain 50.138
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.138
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.135
NCOR2nuclear receptor corepressor 20.134
HIC1hypermethylated in cancer 10.132
COPAcoatomer protein complex, subunit alpha0.131
TBX5T-box 50.129
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.128
EGR1early growth response 10.124
SOX2SRY (sex determining region Y)-box 20.123
CENPJcentromere protein J0.123
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism