The network for 'monoamine transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

monoamine transport

The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NameDescriptionProbabilityFunc Analog Organism
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.997
crhcorticotropin releasing hormone0.920
prom1aprominin 1a0.885
ddcdopa decarboxylase0.782
nlgn4bneuroligin 4b0.772
nlgn1neuroligin 10.678
drd2bdopamine receptor D2b0.530
dab1adisabled homolog 1a (Drosophila)0.412
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.409
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.394
sim1asingle-minded homolog 1a (Drosophila)0.381
chrna6cholinergic receptor, nicotinic, alpha 60.370
zgc:193504zgc:1935040.312
hcrtr2hypocretin (orexin) receptor 20.312
fevFEV (ETS oncogene family)0.310
hspb9heat shock protein, alpha-crystallin-related, 90.303
si:ch211-209p5.2si:ch211-209p5.20.293
tph2tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)0.256
nadl1.2neural adhesion molecule L1.20.249
LOC100002342carboxypeptidase A6-like0.237
recql5RecQ protein-like 50.225
hspb2heat shock protein, alpha-crystallin-related, b20.216
slc6a5solute carrier family 6 (neurotransmitter transporter, glycine), member 50.214
slc6a4asolute carrier family 6 (neurotransmitter transporter, serotonin), member 4A0.205
hsp70heat shock cognate 70-kd protein0.199
blmBloom syndrome0.195
slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.183
ryr2aryanodine receptor 2a (cardiac)0.182
htr1ab5-hydroxytryptamine (serotonin) receptor 1A b0.180
epoerythropoietin0.180
tmietransmembrane inner ear0.176
esrrgaestrogen-related receptor gamma a0.174
lhx3LIM homeobox 30.173
slc30a2solute carrier family 30 (zinc transporter), member 20.171
cpa4carboxypeptidase A40.171
hspb11heat shock protein, alpha-crystallin-related, b110.167
slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b0.160
nrxn2aneurexin 2a0.153
chatcholine acetyltransferase0.150
lhx6LIM homeobox 60.147
drd2ldopamine receptor D2 like0.144
drd2adopamine receptor D2a0.137
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.135
wnt2bawingless-type MMTV integration site family, member 2Ba0.133
sncgasynuclein, gamma a0.133
nlgn4aneuroligin 4a0.129
maomonoamine oxidase0.123
ncs1bneuronal calcium sensor 1b0.123
crhbpcorticotropin releasing hormone binding protein0.115
htr1bd5-hydroxytryptamine (serotonin) receptor 1bd0.115
stx1bsyntaxin 1B0.114
gfra1bgdnf family receptor alpha 1b0.113
cnr1cannabinoid receptor 10.111
oxtloxytocin-like0.111
sema3fbsemaphorin 3fb0.110
atoh1batonal homolog 1b0.105
zgc:112180zgc:1121800.103
opn4aopsin 4a (melanopsin)0.102
lpar1lysophosphatidic acid receptor 10.102
uts1urotensin 10.098
egr1early growth response 10.097
ucn3lurocortin 3, like0.097
zgc:172246zgc:1722460.089
hcrthypocretin (orexin) neuropeptide precursor0.084
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.084
zgc:77409zgc:774090.084
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.083
gdnfglial cell derived neurotrophic factor0.082
foxp2forkhead box P20.079
sema3absemaphorin 3ab0.077
gad2glutamate decarboxylase 20.075
prom1bprominin 1 b0.074
prok2prokineticin 20.074
LOC565839tumor necrosis factor alpha-induced protein 2-like0.073
valopbvertebrate ancient long opsin b0.071
gsx1GS homeobox 10.070
vtg1vitellogenin 10.069
msi1musashi homolog 1 (Drosophila)0.069
drd3dopamine receptor D30.067
LOC100331502melanopsin-B-like0.066
th2tyrosine hydroxylase 20.065
phox2bpaired-like homeobox 2b0.065
cyp1acytochrome P450, family 1, subfamily A0.065
ca10acarbonic anhydrase Xa0.063
ndel1anudE nuclear distribution gene E homolog like 1 (A. nidulans) A0.063
eps8l3EPS8-like 30.063
vegfabvascular endothelial growth factor Ab0.063
gad1bglutamate decarboxylase 1b0.062
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.060
barhl1.1BarH-like 1.10.058
gpm6aaglycoprotein M6Aa0.057
LOC568691opsin-3-like0.055
ghrlghrelin/obestatin preprohormone0.055
dpysl5bdihydropyrimidinase-like 5b0.055
limk1LIM domain kinase 10.055
avplarginine vasopressin-like0.054
fabp7afatty acid binding protein 7, brain, a0.053
kmokynurenine 3-monooxygenase0.053
drd1dopamine receptor D10.053
pi4kbphosphatidylinositol 4-kinase, catalytic, beta0.053
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cat-2Protein CAT-20.026
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SYKspleen tyrosine kinase0.994
PTPN6protein tyrosine phosphatase, non-receptor type 60.977
DRD2dopamine receptor D20.976
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.844
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.748
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.716
ADORA2Aadenosine A2a receptor0.614
UBASH3Bubiquitin associated and SH3 domain containing B0.589
PILRApaired immunoglobin-like type 2 receptor alpha0.538
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.489
DHCR77-dehydrocholesterol reductase0.467
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.304
LCKlymphocyte-specific protein tyrosine kinase0.290
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.253
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.217
PICK1protein interacting with PRKCA 10.207
SIGLEC7sialic acid binding Ig-like lectin 70.181
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.163
HIPK2homeodomain interacting protein kinase 20.124
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.123
FADS2fatty acid desaturase 20.108
VAC14Vac14 homolog (S. cerevisiae)0.105
PTAFRplatelet-activating factor receptor0.083
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.078
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.066
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.061
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.060
EPORerythropoietin receptor0.057
FBXO7F-box protein 70.052
PRKCGprotein kinase C, gamma0.047
HK3hexokinase 3 (white cell)0.041
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.035
HDAC6histone deacetylase 60.031
TOR1AIP2torsin A interacting protein 20.030
PRLHRprolactin releasing hormone receptor0.028
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.027
TPPPtubulin polymerization promoting protein0.027
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.027
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.025
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.023
SNCAIPsynuclein, alpha interacting protein0.019
SH3BP2SH3-domain binding protein 20.019
NSFN-ethylmaleimide-sensitive factor0.018
BLNKB-cell linker0.017
FCGR2CFc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)0.017
NECAB2N-terminal EF-hand calcium binding protein 20.017
TYMPthymidine phosphorylase0.016
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.016
CCR1chemokine (C-C motif) receptor 10.016
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 10.016
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.015
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.015
CD33CD33 molecule0.015
SIRPB1signal-regulatory protein beta 10.014
MAST1microtubule associated serine/threonine kinase 10.014
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.013
MAPTmicrotubule-associated protein tau0.013
ZNF746zinc finger protein 7460.013
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.013
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.012
ATXN7L3ataxin 7-like 30.012
SOD1superoxide dismutase 1, soluble0.011
NLRP3NLR family, pyrin domain containing 30.011
TREM1triggering receptor expressed on myeloid cells 10.010
APLP1amyloid beta (A4) precursor-like protein 10.010
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.010
SYN1synapsin I0.010
RHOrhodopsin0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 31.000
Drd2dopamine receptor D20.993
Ppargperoxisome proliferator activated receptor gamma0.835
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.831
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.820
Slc12a1solute carrier family 12, member 10.797
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.776
Adora2aadenosine A2a receptor0.745
Emx1empty spiracles homolog 1 (Drosophila)0.681
Oprm1opioid receptor, mu 10.634
Chrm3cholinergic receptor, muscarinic 3, cardiac0.605
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.588
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.583
Grid1glutamate receptor, ionotropic, delta 10.571
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.548
Pnpla2patatin-like phospholipase domain containing 20.481
MefvMediterranean fever0.399
Cd247CD247 antigen0.375
Hcsthematopoietic cell signal transducer0.366
Ren1renin 1 structural0.362
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.357
Adrb1adrenergic receptor, beta 10.346
Drd1adopamine receptor D1A0.327
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.308
Krtap5-1keratin associated protein 5-10.305
Klklotho0.303
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.301
Hrh1histamine receptor H10.299
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.295
Gcgrglucagon receptor0.280
Plp1proteolipid protein (myelin) 10.280
Sncasynuclein, alpha0.270
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.267
Slc22a6solute carrier family 22 (organic anion transporter), member 60.260
Trem3triggering receptor expressed on myeloid cells 30.256
Trpv1transient receptor potential cation channel, subfamily V, member 10.255
Cckbrcholecystokinin B receptor0.245
Smyd1SET and MYND domain containing 10.232
Chrna4cholinergic receptor, nicotinic, alpha polypeptide 40.224
Appamyloid beta (A4) precursor protein0.211
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.210
Leprleptin receptor0.210
Nos1nitric oxide synthase 1, neuronal0.209
Npy2rneuropeptide Y receptor Y20.207
Slc6a20bsolute carrier family 6 (neurotransmitter transporter), member 20B0.204
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.203
Adrb3adrenergic receptor, beta 30.200
Mioxmyo-inositol oxygenase0.197
Chrm1cholinergic receptor, muscarinic 1, CNS0.195
Lhx3LIM homeobox protein 30.190
Ighimmunoglobulin heavy chain complex0.188
Apoeapolipoprotein E0.184
Mfn2mitofusin 20.183
Syn2synapsin II0.182
Nodalnodal0.176
Kitkit oncogene0.172
Ntsr2neurotensin receptor 20.171
Cd22CD22 antigen0.170
Thtyrosine hydroxylase0.169
Gsx1GS homeobox 10.165
Clockcircadian locomotor output cycles kaput0.164
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.163
Adra2badrenergic receptor, alpha 2b0.159
Mas1MAS1 oncogene0.159
Agrpagouti related protein0.154
Kcns2K+ voltage-gated channel, subfamily S, 20.151
Gpr3G-protein coupled receptor 30.151
Shc3src homology 2 domain-containing transforming protein C30.144
Acsm2acyl-CoA synthetase medium-chain family member 20.143
Syt6synaptotagmin VI0.140
Mbmyoglobin0.139
TyrobpTYRO protein tyrosine kinase binding protein0.136
Slc6a18solute carrier family 6 (neurotransmitter transporter), member 180.135
Col4a3collagen, type IV, alpha 30.134
Clcnkachloride channel Ka0.133
Gpr83G protein-coupled receptor 830.132
Gjc2gap junction protein, gamma 20.131
Arntlaryl hydrocarbon receptor nuclear translocator-like0.129
Zfp92zinc finger protein 920.126
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.126
Gjd2gap junction protein, delta 20.125
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.125
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.122
Inhbcinhibin beta-C0.121
Sstr4somatostatin receptor 40.120
Acheacetylcholinesterase0.120
Gpr33G protein-coupled receptor 330.118
Chrna10cholinergic receptor, nicotinic, alpha polypeptide 100.118
Scn10asodium channel, voltage-gated, type X, alpha0.117
Tbxa2rthromboxane A2 receptor0.114
Nr2e1nuclear receptor subfamily 2, group E, member 10.114
Inpp5dinositol polyphosphate-5-phosphatase D0.114
Crhr1corticotropin releasing hormone receptor 10.113
Htr45 hydroxytryptamine (serotonin) receptor 40.112
Htr3a5-hydroxytryptamine (serotonin) receptor 3A0.109
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.107
Sypl2synaptophysin-like 20.106
Esr1estrogen receptor 1 (alpha)0.105
Krt12keratin 120.104
Ccl2chemokine (C-C motif) ligand 20.103
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.751
Oprk1opioid receptor, kappa 10.300
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.299
Slc7a3solute carrier family 7 (cationic amino acid transporter, y+ system), member 30.186
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.168
FevFEV (ETS oncogene family)0.159
Chrnb1cholinergic receptor, nicotinic, beta 1 (muscle)0.159
Gria2glutamate receptor, ionotropic, AMPA 20.157
Ghrhrgrowth hormone releasing hormone receptor0.144
Esr1estrogen receptor 10.138
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.136
Olr416olfactory receptor 4160.135
Csf3colony stimulating factor 3 (granulocyte)0.124
Grm2glutamate receptor, metabotropic 20.123
Drd2dopamine receptor D20.121
Gcm1glial cells missing homolog 1 (Drosophila)0.117
Atp7bATPase, Cu++ transporting, beta polypeptide0.116
UncxUNC homeobox0.116
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.115
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.113
Pitx3paired-like homeodomain 30.110
Slc22a25solute carrier family 22, member 250.110
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.100
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.099
Smad3SMAD family member 30.096
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.093
Esr2estrogen receptor 2 (ER beta)0.092
Cacng5calcium channel, voltage-dependent, gamma subunit 50.089
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.087
LOC286987hemiferrin, transferrin-like protein0.086
Kcng1potassium voltage-gated channel, subfamily G, member 10.086
Adora1adenosine A1 receptor0.084
Mmp7matrix metallopeptidase 70.084
Dlg4discs, large homolog 4 (Drosophila)0.084
Olr1361olfactory receptor 13610.083
Prm3protamine 30.082
RGD1565859RGD15658590.080
Dock8dedicator of cytokinesis 80.079
Crhbpcorticotropin releasing hormone binding protein0.078
Olr1078olfactory receptor 10780.078
Tbxa2rthromboxane A2 receptor0.078
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.077
Mylk2myosin light chain kinase 20.075
Chrnecholinergic receptor, nicotinic, epsilon0.073
Tacr2tachykinin receptor 20.073
Crhr2corticotropin releasing hormone receptor 20.072
Zg16zymogen granule protein 160.069
Phkg1phosphorylase kinase, gamma 10.069
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.069
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.068
Scn5asodium channel, voltage-gated, type V, alpha subunit0.068
Folh1folate hydrolase 10.067
Chrndcholinergic receptor, nicotinic, delta0.066
Slc22a7solute carrier family 22 (organic anion transporter), member 70.066
Acrv1acrosomal vesicle protein 10.065
Fam65afamily with sequence similarity 65, member A0.065
Tpbpatrophoblast specific protein alpha0.065
Gcgglucagon0.064
Chrnb2cholinergic receptor, nicotinic, beta 2 (neuronal)0.063
Il2rainterleukin 2 receptor, alpha0.062
Gfra2GDNF family receptor alpha 20.062
Spp2secreted phosphoprotein 20.061
Prlhrprolactin releasing hormone receptor0.060
Psg19pregnancy specific glycoprotein 190.060
Kcnb2potassium voltage gated channel, Shab-related subfamily, member 20.060
Slc6a18solute carrier family 6, member 180.060
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.060
Adora2aadenosine A2a receptor0.059
Atp2c2ATPase, Ca++ transporting, type 2C, member 20.058
Trhr2thyrotropin releasing hormone receptor 20.058
Pzppregnancy-zone protein0.057
Hrh2histamine receptor H 20.057
Avparginine vasopressin0.056
Vom2r53vomeronasal 2 receptor, 530.056
Gpr12G protein-coupled receptor 120.056
Htr3a5-hydroxytryptamine (serotonin) receptor 3a0.056
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.055
Rin1Ras and Rab interactor 10.055
Hcrthypocretin0.055
Aqp2aquaporin 2 (collecting duct)0.054
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.054
Tontonin0.053
Pomcproopiomelanocortin0.053
Vom2r27vomeronasal 2 receptor, 270.053
Rgs9regulator of G-protein signaling 90.053
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.052
Hist1h2aahistone cluster 1, H2aa0.052
Grpgastrin releasing peptide0.052
Prss1protease, serine, 1 (trypsin 1)0.052
Chrna7cholinergic receptor, nicotinic, alpha 70.052
Prlprolactin0.052
Slc30a2solute carrier family 30 (zinc transporter), member 20.051
Vipvasoactive intestinal peptide0.051
Cmklr1chemokine-like receptor 10.050
LOC100362817rCG33447-like0.050
Slco2b1solute carrier organic anion transporter family, member 2b10.049
Zp1zona pellucida glycoprotein 1 (sperm receptor)0.049
Tnfrsf8tumor necrosis factor receptor superfamily, member 80.049
Pou3f4POU class 3 homeobox 40.048
Pde1bphosphodiesterase 1B, calmodulin-dependent0.048
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism