The network for 'vesicle targeting' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

vesicle targeting

The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Atg2Autophagy-specific gene 20.065
PcafCG4107 gene product from transcript CG4107-RA0.033
baibaiser0.024
Atg1Autophagy-specific gene 10.021
StimStromal interaction molecule0.016
Cip4CG15015 gene product from transcript CG15015-RA0.012
CHOp24CG3564 gene product from transcript CG3564-RA0.011
ash2absent, small, or homeotic discs 20.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SURF4surfeit 40.356
CUL3cullin 30.305
DAPK1death-associated protein kinase 10.148
ARF4ADP-ribosylation factor 40.092
SEC24DSEC24 family, member D (S. cerevisiae)0.068
PKP4plakophilin 40.067
BTBD10BTB (POZ) domain containing 100.065
KBTBD7kelch repeat and BTB (POZ) domain containing 70.058
GORASP2golgi reassembly stacking protein 2, 55kDa0.053
WNK4WNK lysine deficient protein kinase 40.048
COPB1coatomer protein complex, subunit beta 10.045
PSEN2presenilin 2 (Alzheimer disease 4)0.043
SPOPspeckle-type POZ protein0.042
TMED2transmembrane emp24 domain trafficking protein 20.036
NFE2L2nuclear factor (erythroid-derived 2)-like 20.035
ARCN1archain 10.029
TRIP6thyroid hormone receptor interactor 60.024
FLNBfilamin B, beta0.020
COPAcoatomer protein complex, subunit alpha0.020
DLG4discs, large homolog 4 (Drosophila)0.020
MLPHmelanophilin0.017
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.014
COPB2coatomer protein complex, subunit beta 2 (beta prime)0.014
PRMT6protein arginine methyltransferase 60.011
CUL2cullin 20.010
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Notch2Notch gene homolog 2 (Drosophila)0.244
Ncstnnicastrin0.149
Notch1Notch gene homolog 1 (Drosophila)0.138
Erlin2ER lipid raft associated 20.054
Aph1aanterior pharynx defective 1a homolog (C. elegans)0.032
Psen1presenilin 10.032
Mks1Meckel syndrome, type 10.032
Tctn1tectonic family member 10.030
Psen2presenilin 20.025
Sytl5synaptotagmin-like 50.020
Appamyloid beta (A4) precursor protein0.020
Smad4MAD homolog 4 (Drosophila)0.016
Ctnnb1catenin (cadherin associated protein), beta 10.014
Smad1MAD homolog 1 (Drosophila)0.013
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ERV25Erv25p0.073
SEC24Sec24p0.036
ERP4Erp4p0.031
SEC16Sec16p0.027
SAR1Sar1p0.023
EMP24Emp24p0.019
SED5Sed5p0.018
SEC31Sec31p0.016
ERP3Erp3p0.016
SFB2Sfb2p0.016
SEC13Sec13p0.016
YPT1Ypt1p0.014
CPT1Cpt1p0.013
GYL1Gyl1p0.011
VPS74Vps74p0.010