The network for 'negative regulation of protein transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NameDescriptionProbabilityFunc Analog Organism
capns1acalpain, small subunit 1 a0.790
igf1rbinsulin-like growth factor 1b receptor0.642
anxa1cannexin A1c0.589
nf1aneurofibromin 1a0.514
anxa1bannexin A1b0.359
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.320
appaamyloid beta (A4) precursor protein a0.283
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.260
krt4keratin 40.253
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.250
plk1polo-like kinase 1 (Drosophila)0.235
cdc20cell division cycle 20 homolog0.228
ext2exostoses (multiple) 20.217
sulf1sulfatase 10.215
lfnglunatic fringe homolog0.200
esrraestrogen-related receptor alpha0.196
capns1bcalpain, small subunit 1 b0.194
gdf6agrowth differentiation factor 6a0.190
ip6k2inositol hexaphosphate kinase 20.185
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.183
anxa1aannexin A1a0.182
LOC100535549cytoplasmic polyadenylation element-binding protein 4-like0.182
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.170
actr1ARP1 actin-related protein 1, centractin (yeast)0.167
krt5keratin 50.158
cdh1cadherin 1, epithelial0.151
aplnraapelin receptor a0.147
nuf2NUF2, NDC80 kinetochore complex component, homolog0.147
prox1prospero-related homeobox gene 10.145
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.142
abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 50.141
cldneclaudin e0.140
wlswntless homolog (Drosophila)0.136
anxa2aannexin A2a0.132
ptgs2aprostaglandin-endoperoxide synthase 2a0.131
btg2B-cell translocation gene 20.129
sepw2bselenoprotein W, 2b0.128
esrp1epithelial splicing regulatory protein 10.128
cd63Cd63 antigen0.125
rbm22RNA binding motif protein 220.124
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.123
nf1bneurofibromin 1b0.122
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.121
sdprbserum deprivation response b0.120
adra2cadrenergic, alpha-2C-, receptor0.120
trpv4transient receptor potential cation channel, subfamily V, member 40.120
thrabthyroid hormone receptor alpha b0.117
meis1myeloid ecotropic viral integration 10.117
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.116
idsiduronate 2-sulfatase0.115
jag2jagged 20.114
pik3r3phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)0.112
drd2adopamine receptor D2a0.110
LOC567452G protein-coupled receptor kinase 5-like0.110
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.109
tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.107
gli2aGLI-Kruppel family member GLI2a0.105
fbn2bfibrillin 2b0.105
cox8acytochrome c oxidase subunit 8a0.101
tuba1tubulin, alpha 10.101
zeb1zinc finger E-box binding homeobox 10.101
her1hairy-related 10.101
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.101
sdpraserum deprivation response a0.100
foxj1aforkhead box J1a0.099
ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.096
epas1bendothelial PAS domain protein 1b0.095
ddx3DEAD (Asp-Glu-Ala-Asp) box polypeptide 30.092
birc5abaculoviral IAP repeat-containing 5a0.091
nr2f6bnuclear receptor subfamily 2, group F, member 6b0.091
ints6integrator complex subunit 60.090
thraathyroid hormone receptor alpha a0.090
ahnakAHNAK nucleoprotein0.089
uspl1ubiquitin specific peptidase like 10.088
capn9calpain 90.087
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.086
vgll4lvestigial like 4 like0.085
ptmaaprothymosin, alpha a0.084
srfserum response factor0.082
adra2badrenergic, alpha-2B-, receptor0.081
dynlrb1dynein, light chain, roadblock-type 10.081
cfl1cofilin 1 (non-muscle)0.081
ppp2r5eaprotein phosphatase 2, regulatory subunit B', epsilon isoform a0.079
pkp3plakophilin 30.079
fzd5frizzled homolog 50.078
ptgesprostaglandin E synthase0.078
anxa13annexin A130.078
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.077
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.993
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.978
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.962
GSK3Bglycogen synthase kinase 3 beta0.953
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.931
C1QAcomplement component 1, q subcomponent, A chain0.867
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.862
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.820
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.788
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.766
YAP1Yes-associated protein 10.742
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.730
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.699
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.660
NEDD4neural precursor cell expressed, developmentally down-regulated 40.627
ANXA1annexin A10.627
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.584
DTX3Ldeltex 3-like (Drosophila)0.549
FBXW11F-box and WD repeat domain containing 110.494
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.460
SMAD2SMAD family member 20.452
CREBBPCREB binding protein0.432
MDM2Mdm2 p53 binding protein homolog (mouse)0.424
MAP3K5mitogen-activated protein kinase kinase kinase 50.416
MAP3K3mitogen-activated protein kinase kinase kinase 30.411
RNF11ring finger protein 110.391
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.357
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.352
FLNAfilamin A, alpha0.339
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.331
SMURF2SMAD specific E3 ubiquitin protein ligase 20.325
PMLpromyelocytic leukemia0.314
IGF1Rinsulin-like growth factor 1 receptor0.295
BTRCbeta-transducin repeat containing0.295
PILRApaired immunoglobin-like type 2 receptor alpha0.295
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.294
HIPK2homeodomain interacting protein kinase 20.294
SMAD7SMAD family member 70.292
TP53tumor protein p530.285
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.273
MED15mediator complex subunit 150.266
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.261
HIPK3homeodomain interacting protein kinase 30.246
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.241
PKD2polycystic kidney disease 2 (autosomal dominant)0.239
S100A10S100 calcium binding protein A100.232
IQGAP1IQ motif containing GTPase activating protein 10.220
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.217
AXLAXL receptor tyrosine kinase0.217
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.211
CHUKconserved helix-loop-helix ubiquitous kinase0.210
CAV1caveolin 1, caveolae protein, 22kDa0.204
TNFAIP3tumor necrosis factor, alpha-induced protein 30.203
MAP3K1mitogen-activated protein kinase kinase kinase 10.203
SMAD4SMAD family member 40.194
SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.194
TNIP2TNFAIP3 interacting protein 20.186
PSEN1presenilin 10.184
PAX3paired box 30.182
SMN1survival of motor neuron 1, telomeric0.175
RARAretinoic acid receptor, alpha0.172
C1QCcomplement component 1, q subcomponent, C chain0.166
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.155
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.150
UBCubiquitin C0.149
MAP3K8mitogen-activated protein kinase kinase kinase 80.149
PKD1polycystic kidney disease 1 (autosomal dominant)0.147
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.146
ZNF263zinc finger protein 2630.139
ANXA7annexin A70.135
APOC1apolipoprotein C-I0.130
MAP2K5mitogen-activated protein kinase kinase 50.126
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.126
SKP1S-phase kinase-associated protein 10.122
TRIM39tripartite motif containing 390.118
POU3F2POU class 3 homeobox 20.116
ADORA2Aadenosine A2a receptor0.114
CDC25Bcell division cycle 25 homolog B (S. pombe)0.113
DAXXdeath-domain associated protein0.107
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.106
PRDX1peroxiredoxin 10.105
TUBA1Atubulin, alpha 1a0.104
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.104
PSEN2presenilin 2 (Alzheimer disease 4)0.104
IRS1insulin receptor substrate 10.098
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.097
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.096
ERBB2IPerbb2 interacting protein0.093
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.093
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.093
ACTN4actinin, alpha 40.092
CSKc-src tyrosine kinase0.092
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.091
CKAP5cytoskeleton associated protein 50.091
LZTS2leucine zipper, putative tumor suppressor 20.089
PLSCR1phospholipid scramblase 10.088
ARRB1arrestin, beta 10.086
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Casp4caspase 4, apoptosis-related cysteine peptidase0.753
Casp1caspase 10.703
Apcadenomatosis polyposis coli0.578
Pax8paired box gene 80.467
Ctnnb1catenin (cadherin associated protein), beta 10.449
Esr1estrogen receptor 1 (alpha)0.368
S1pr2sphingosine-1-phosphate receptor 20.283
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.264
Rargretinoic acid receptor, gamma0.230
Ghrgrowth hormone receptor0.229
Grb10growth factor receptor bound protein 100.224
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.195
Trp63transformation related protein 630.166
Ptenphosphatase and tensin homolog0.160
Traf1TNF receptor-associated factor 10.153
Pdcd1programmed cell death 10.152
Axin1axin 10.139
Bcl6B-cell leukemia/lymphoma 60.138
Gbp2guanylate binding protein 20.135
Gli3GLI-Kruppel family member GLI30.131
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.130
Duox2dual oxidase 20.126
Wnt5awingless-related MMTV integration site 5A0.122
Thrbthyroid hormone receptor beta0.117
Trp53transformation related protein 530.115
Rararetinoic acid receptor, alpha0.113
Tnftumor necrosis factor0.113
Dlg2discs, large homolog 2 (Drosophila)0.102
Smosmoothened homolog (Drosophila)0.099
Dlg4discs, large homolog 4 (Drosophila)0.099
Twist2twist homolog 2 (Drosophila)0.097
Nedd4neural precursor cell expressed, developmentally down-regulated 40.096
Dlg1discs, large homolog 1 (Drosophila)0.095
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.092
Arandrogen receptor0.090
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.086
Ntn1netrin 10.085
Cdkn1bcyclin-dependent kinase inhibitor 1B0.081
Il1rl1interleukin 1 receptor-like 10.081
Rnf115ring finger protein 1150.078
Gbp7guanylate binding protein 70.077
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.074
WwoxWW domain-containing oxidoreductase0.073
RrasHarvey rat sarcoma oncogene, subgroup R0.069
Irf7interferon regulatory factor 70.068
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.068
Prlrprolactin receptor0.068
Serpinb9serine (or cysteine) peptidase inhibitor, clade B, member 90.067
Ikbkbinhibitor of kappaB kinase beta0.066
Bcap31B-cell receptor-associated protein 310.066
Ltalymphotoxin A0.066
Txndc17thioredoxin domain containing 170.065
Gli2GLI-Kruppel family member GLI20.062
Gpr33G protein-coupled receptor 330.062
Traf2TNF receptor-associated factor 20.060
Fgfr2fibroblast growth factor receptor 20.060
Nr0b2nuclear receptor subfamily 0, group B, member 20.060
Gopcgolgi associated PDZ and coiled-coil motif containing0.059
Ifit2interferon-induced protein with tetratricopeptide repeats 20.059
Rxraretinoid X receptor alpha0.059
Col4a5collagen, type IV, alpha 50.059
Fzd8frizzled homolog 8 (Drosophila)0.058
Il12rb2interleukin 12 receptor, beta 20.058
Fgf10fibroblast growth factor 100.058
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.058
Meox2mesenchyme homeobox 20.057
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.055
Irs1insulin receptor substrate 10.055
Gbp6guanylate binding protein 60.054
Gbp3guanylate binding protein 30.053
Mdm2transformed mouse 3T3 cell double minute 20.052
Rarbretinoic acid receptor, beta0.052
Ifi203interferon activated gene 2030.052
Zfp316zinc finger protein 3160.052
Phldb2pleckstrin homology-like domain, family B, member 20.052
Mndalmyeloid nuclear differentiation antigen like0.052
Tigd5tigger transposable element derived 50.051
Igtpinterferon gamma induced GTPase0.051
Iigp1interferon inducible GTPase 10.051
Rbl2retinoblastoma-like 20.051
Traf6TNF receptor-associated factor 60.050
Fgfr1fibroblast growth factor receptor 10.049
Add1adducin 1 (alpha)0.049
Apoeapolipoprotein E0.049
Asah1N-acylsphingosine amidohydrolase 10.049
Lag3lymphocyte-activation gene 30.049
Bglapbone gamma carboxyglutamate protein0.048
Rnh1ribonuclease/angiogenin inhibitor 10.048
Irgm2immunity-related GTPase family M member 20.047
Ahraryl-hydrocarbon receptor0.047
Gpr132G protein-coupled receptor 1320.046
Clk1CDC-like kinase 10.046
Ikbkginhibitor of kappaB kinase gamma0.045
Cd274CD274 antigen0.045
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae)0.045
Zfp444zinc finger protein 4440.045
B2mbeta-2 microglobulin0.044
Ncam1neural cell adhesion molecule 10.042
Ifih1interferon induced with helicase C domain 10.042
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
S100a10S100 calcium binding protein A100.455
Lgals3lectin, galactoside-binding, soluble, 30.226
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.115
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.062
siat7Dalpha-2,6-sialyltransferase ST6GalNAc IV0.061
S100a6S100 calcium binding protein A60.061
Cd151CD151 molecule (Raph blood group)0.056
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.055
Nckap1NCK-associated protein 10.044
Fabp4fatty acid binding protein 4, adipocyte0.043
Ptp4a1protein tyrosine phosphatase type IVA, member 10.042
Stat5bsignal transducer and activator of transcription 5B0.041
Anxa1annexin A10.040
Anxa2annexin A20.035
Trim17tripartite motif-containing 170.033
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.033
Sdc3syndecan 30.032
Rhobras homolog gene family, member B0.031
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.030
Anxa5annexin A50.028
Junbjun B proto-oncogene0.027
Capn2calpain 20.027
S100a11S100 calcium binding protein A11 (calizzarin)0.027
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.025
Rararetinoic acid receptor, alpha0.024
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.022
Stat6signal transducer and activator of transcription 60.021
Prnpprion protein0.021
Klf9Kruppel-like factor 90.021
Itpr2inositol 1,4,5-triphosphate receptor, type 20.019
Cacna1icalcium channel, voltage-dependent, T type, alpha 1I subunit0.018
LOC683077similar to praja1, RING-H2 motif containing0.017
Myadmmyeloid-associated differentiation marker0.017
Ccl2chemokine (C-C motif) ligand 20.017
Rab7aRAB7A, member RAS oncogene family0.016
Slc14a2solute carrier family 14 (urea transporter), member 20.016
Apbb1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.016
Olr1654olfactory receptor 16540.016
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.015
Edn2endothelin 20.015
Neurl2neuralized homolog 2 (Drosophila)0.015
Rc3h2ring finger and CCCH-type zinc finger domains 20.015
Rab11aRAB11a, member RAS oncogene family0.015
Epn2epsin 20.014
Ideinsulin degrading enzyme0.014
Ifrd1interferon-related developmental regulator 10.014
Tnip1TNFAIP3 interacting protein 10.014
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.014
Ccdc91coiled-coil domain containing 910.014
Csnk1g2casein kinase 1, gamma 20.014
Pfkpphosphofructokinase, platelet0.014
Rexo2REX2, RNA exonuclease 2 homolog (S. cerevisiae)0.014
Sgk1serum/glucocorticoid regulated kinase 10.013
Acsm5acyl-CoA synthetase medium-chain family member 50.013
Nedd4neural precursor cell expressed, developmentally down-regulated 40.013
Mpripmyosin phosphatase Rho interacting protein0.013
Pcnxl3pecanex-like 3 (Drosophila)0.013
Cacng4calcium channel, voltage-dependent, gamma subunit 40.013
Usp14ubiquitin specific peptidase 140.013
Vegfavascular endothelial growth factor A0.013
Vom1r97vomeronasal 1 receptor 970.012
Mipmajor intrinsic protein of lens fiber0.012
Oaz2ornithine decarboxylase antizyme 20.012
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.012
Lpllipoprotein lipase0.012
Mark2MAP/microtubule affinity-regulating kinase 20.012
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.012
Ctnna1catenin (cadherin associated protein), alpha 10.012
Lphn1latrophilin 10.012
Taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.012
Pgm1phosphoglucomutase 10.012
Pitpnaphosphatidylinositol transfer protein, alpha0.012
Psmb7proteasome (prosome, macropain) subunit, beta type 70.012
Snx3sorting nexin 30.012
Ahraryl hydrocarbon receptor0.011
Cnn3calponin 3, acidic0.011
ZwintZW10 interactor0.011
RragaRas-related GTP binding A0.011
Ptpn11protein tyrosine phosphatase, non-receptor type 110.011
Cpsf6cleavage and polyadenylation specific factor 60.011
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.011
Fam189bfamily with sequence similarity 189, member B0.011
Cnga4cyclic nucleotide gated channel alpha 40.011
Gdi1GDP dissociation inhibitor 10.011
Tgfbr3transforming growth factor, beta receptor III0.011
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.011
Avparginine vasopressin0.011
Nrd1nardilysin 10.011
Ireb2iron responsive element binding protein 20.011
Dcaf8DDB1 and CUL4 associated factor 80.011
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.011
Rnf14ring finger protein 140.010
Foxi2forkhead box I20.010
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.010
Errfi1ERBB receptor feedback inhibitor 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism