IMP
Process View
The network for 'positive regulation of bone remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of bone remodeling
Any process that activates or increases the frequency, rate or extent of bone remodeling.
| Name | Description | Probability | Func Analog Organism |
|---|
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Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.074 | |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.044 | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.038 | |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.021 | |
| ITK | IL2-inducible T-cell kinase | 0.016 | |
| SH3BP4 | SH3-domain binding protein 4 | 0.015 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.015 | |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.013 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.012 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.010 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.010 |
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Mus musculus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ltbp2 | latent transforming growth factor beta binding protein 2 | 0.729 | |
| Col1a1 | collagen, type I, alpha 1 | 0.432 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.398 | |
| Eln | elastin | 0.352 | |
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.340 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.316 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.307 | |
| Cav1 | caveolin 1, caveolae protein | 0.302 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.278 | |
| Agtr2 | angiotensin II receptor, type 2 | 0.272 | |
| Itgb3 | integrin beta 3 | 0.264 | |
| Cd22 | CD22 antigen | 0.244 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.227 | |
| Fbn1 | fibrillin 1 | 0.222 | |
| Gja1 | gap junction protein, alpha 1 | 0.218 | |
| Hic1 | hypermethylated in cancer 1 | 0.198 | |
| Jag1 | jagged 1 | 0.192 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.159 | |
| Mmp2 | matrix metallopeptidase 2 | 0.146 | |
| Lox | lysyl oxidase | 0.145 | |
| Adam15 | a disintegrin and metallopeptidase domain 15 (metargidin) | 0.141 | |
| Pomc | pro-opiomelanocortin-alpha | 0.126 | |
| Igk | immunoglobulin kappa chain complex | 0.119 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.110 | |
| Idua | iduronidase, alpha-L- | 0.102 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.102 | |
| Xcr1 | chemokine (C motif) receptor 1 | 0.100 | |
| Foxc2 | forkhead box C2 | 0.093 | |
| Ldlr | low density lipoprotein receptor | 0.091 | |
| Bmp1 | bone morphogenetic protein 1 | 0.090 | |
| Col6a2 | collagen, type VI, alpha 2 | 0.087 | |
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.083 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.082 | |
| Adam12 | a disintegrin and metallopeptidase domain 12 (meltrin alpha) | 0.079 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.078 | |
| Thbs2 | thrombospondin 2 | 0.076 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.075 | |
| Ngp | neutrophilic granule protein | 0.072 | |
| Mc5r | melanocortin 5 receptor | 0.068 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.067 | |
| Pax1 | paired box gene 1 | 0.065 | |
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.059 | |
| Col6a1 | collagen, type VI, alpha 1 | 0.058 | |
| Pdgfb | platelet derived growth factor, B polypeptide | 0.058 | |
| Ciita | class II transactivator | 0.052 | |
| Mcam | melanoma cell adhesion molecule | 0.051 | |
| Aebp1 | AE binding protein 1 | 0.050 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.050 | |
| Ctsk | cathepsin K | 0.050 | |
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.050 | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.049 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.049 | |
| Ppargc1b | peroxisome proliferative activated receptor, gamma, coactivator 1 beta | 0.049 | |
| Egfr | epidermal growth factor receptor | 0.049 | |
| Jup | junction plakoglobin | 0.047 | |
| Wisp2 | WNT1 inducible signaling pathway protein 2 | 0.047 | |
| Creb3l1 | cAMP responsive element binding protein 3-like 1 | 0.046 | |
| Prg3 | proteoglycan 3 | 0.045 | |
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.044 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.042 | |
| Gp5 | glycoprotein 5 (platelet) | 0.042 | |
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.041 | |
| Col6a3 | collagen, type VI, alpha 3 | 0.041 | |
| C1qtnf1 | C1q and tumor necrosis factor related protein 1 | 0.040 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.040 | |
| Wwp1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.040 | |
| Fn1 | fibronectin 1 | 0.039 | |
| Axin1 | axin 1 | 0.038 | |
| Mageb3 | melanoma antigen, family B, 3 | 0.037 | |
| Vipr2 | vasoactive intestinal peptide receptor 2 | 0.037 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.037 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.037 | |
| Fut7 | fucosyltransferase 7 | 0.035 | |
| Sod3 | superoxide dismutase 3, extracellular | 0.035 | |
| Apoe | apolipoprotein E | 0.035 | |
| Prlr | prolactin receptor | 0.035 | |
| Col5a1 | collagen, type V, alpha 1 | 0.035 | |
| Tgfbr1 | transforming growth factor, beta receptor I | 0.035 | |
| Col1a2 | collagen, type I, alpha 2 | 0.035 | |
| Lama5 | laminin, alpha 5 | 0.034 | |
| Lamc2 | laminin, gamma 2 | 0.034 | |
| Npy1r | neuropeptide Y receptor Y1 | 0.034 | |
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.034 | |
| Ccr1l1 | chemokine (C-C motif) receptor 1-like 1 | 0.033 | |
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.033 | |
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.033 | |
| Slc11a2 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 0.032 | |
| Epha6 | Eph receptor A6 | 0.032 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.031 | |
| Itga5 | integrin alpha 5 (fibronectin receptor alpha) | 0.030 | |
| Svep1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.030 | |
| Star | steroidogenic acute regulatory protein | 0.030 | |
| Ddr2 | discoidin domain receptor family, member 2 | 0.029 | |
| Lat | linker for activation of T cells | 0.029 | |
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.029 | |
| C5ar1 | complement component 5a receptor 1 | 0.028 | |
| Hbegf | heparin-binding EGF-like growth factor | 0.028 | |
| Igj | immunoglobulin joining chain | 0.027 | |
| Chad | chondroadherin | 0.027 | |
| Cd180 | CD180 antigen | 0.027 |