The network for 'heterocycle biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

heterocycle biosynthetic process

The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.995
pitx3paired-like homeodomain transcription factor 30.989
tbx18T-box 180.988
gli1GLI-Kruppel family member 10.987
ndr2nodal-related 20.985
smyhc1slow myosin heavy chain 10.983
pcnaproliferating cell nuclear antigen0.983
tbx20T-box 200.983
foxa2forkhead box A20.982
notch1anotch homolog 1a0.976
foxi1forkhead box I10.975
kdrlkinase insert domain receptor like0.964
lmx1b.1LIM homeobox transcription factor 1, beta 10.962
etv2ets variant gene 20.961
whsc1Wolf-Hirschhorn syndrome candidate 10.960
tal1T-cell acute lymphocytic leukemia 10.958
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.955
dlx5adistal-less homeobox gene 5a0.954
klf4Kruppel-like factor 40.953
foxd3forkhead box D30.951
snai1asnail homolog 1a (Drosophila)0.944
fgf3fibroblast growth factor 30.943
pcdh18bprotocadherin 18b0.939
gata6GATA-binding protein 60.938
her8ahairy-related 8a0.938
egr1early growth response 10.934
otx1borthodenticle homolog 1b0.931
spry4sprouty (Drosophila) homolog 40.924
hnf1baHNF1 homeobox Ba0.921
sox17SRY-box containing gene 170.916
bocbrother of CDO0.907
pax3apaired box gene 3a0.907
eomesaeomesodermin homolog a0.904
fezf2FEZ family zinc finger 20.903
oxtloxytocin-like0.903
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.902
lef1lymphocyte enhancer binding factor 10.898
her7hairy and enhancer of split related-70.898
mespamesoderm posterior a0.894
otpaorthopedia homolog a0.887
twist3twist30.887
rxrbbretinoid x receptor, beta b0.881
otx2orthodenticle homolog 20.871
robo3roundabout homolog 30.866
sox32SRY-box containing gene 320.866
esr2aestrogen receptor 2a0.864
dlx2adistal-less homeobox gene 2a0.859
bmp4bone morphogenetic protein 40.858
runx2brunt-related transcription factor 2b0.856
brd4bromodomain containing 40.855
cry1acryptochrome 1a0.854
ptf1apancreas specific transcription factor, 1a0.853
snai1bsnail homolog 1b (Drosophila)0.849
gpr126G protein-coupled receptor 1260.848
dlddeltaD0.848
shhbsonic hedgehog b0.846
lhx5LIM homeobox 50.837
emx3empty spiracles homeobox 30.837
lft1lefty10.834
per2period homolog 2 (Drosophila)0.823
nr2e1nuclear receptor subfamily 2, group E, member 10.818
zic1zic family member 1 (odd-paired homolog, Drosophila)0.816
irx4biroquois homeobox protein 4b0.815
olfm2olfactomedin 20.810
nanos3nanos homolog 30.810
tll1tolloid-like 10.809
nkx2.5NK2 transcription factor related 50.803
rargbretinoic acid receptor, gamma b0.799
pitx2paired-like homeodomain transcription factor 20.785
hoxd4ahomeo box D4a0.774
atoh1batonal homolog 1b0.773
oprm1opioid receptor, mu 10.773
nrg2aneuregulin 2a0.771
foxj1aforkhead box J1a0.763
pax8paired box gene 80.759
six1bsine oculis homeobox homolog 1b0.758
rx3retinal homeobox gene 30.758
brd2abromodomain-containing 2a0.756
mecomMDS1 and EVI1 complex locus0.754
foxa3forkhead box A30.754
mab21l2mab-21-like 20.752
runx2arunt-related transcription factor 2a0.747
mstnbmyostatin b0.746
raraaretinoic acid receptor, alpha a0.745
chdchordin0.744
arandrogen receptor0.740
ascl1aachaete-scute complex-like 1a (Drosophila)0.738
dlcdeltaC0.737
zic2bzic family member 2 (odd-paired homolog, Drosophila) b0.735
hand2heart and neural crest derivatives expressed transcript 20.732
isl1islet10.729
ntn1anetrin 1a0.729
cav1caveolin 10.729
prox1prospero-related homeobox gene 10.727
clockclock0.725
sox7SRY-box containing gene 70.722
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.718
rarabretinoic acid receptor, alpha b0.718
loxl2blysyl oxidase-like 2b0.715
fzd7afrizzled homolog 7a0.712
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.998
nhr-49Protein NHR-490.983
elt-6Protein ELT-60.978
hlh-2Protein HLH-20.934
pha-4Protein PHA-40.929
nhr-67Protein NHR-670.923
nhr-2Protein NHR-20.889
cnd-1Protein CND-10.848
npp-2Protein NPP-20.846
ceh-20Protein CEH-200.844
fkh-2Protein FKH-20.840
dlk-1Protein DLK-10.750
hda-2Protein HDA-20.746
let-502Protein LET-5020.736
mep-1Protein MEP-10.717
vab-3Protein VAB-30.704
egl-46Protein EGL-460.699
srgp-1Protein SRGP-10.699
F39B2.1Protein F39B2.10.693
zip-7Protein ZIP-70.686
rad-26Protein RAD-260.686
wrm-1Protein WRM-10.678
ten-1Protein TEN-10.677
egl-13Protein EGL-130.671
daf-14Protein DAF-140.671
lin-35Protein LIN-350.667
his-16Protein HIS-160.666
set-2Protein SET-20.656
npp-19Protein NPP-190.653
bet-1Protein BET-10.635
ztf-2Protein ZTF-20.624
R07E4.5Protein R07E4.50.606
his-1Protein HIS-10.604
his-64Protein HIS-640.597
skp-1Protein SKP-10.589
npp-7Protein NPP-70.585
cam-1Protein CAM-10.581
egl-27Protein EGL-270.549
hcp-3Protein HCP-30.547
smp-1Protein SMP-10.544
cfim-2Protein CFIM-20.533
nhr-6Protein NHR-60.530
patr-1Protein PATR-10.530
T28F4.1Protein T28F4.10.518
pop-1Protein POP-10.514
F53F10.2Protein F53F10.20.501
rpb-11Protein RPB-110.497
mab-5Protein MAB-50.491
ceh-27Protein CEH-270.489
sma-6Protein SMA-60.483
pmk-1Protein PMK-10.482
peb-1Protein PEB-10.476
gei-4Protein GEI-40.468
pkg-1Protein PKG-10.466
scc-1Protein SCC-10.465
flh-2Protein FLH-20.465
daf-1Protein DAF-10.458
hif-1Protein HIF-10.452
lin-11Protein LIN-110.451
ida-1Protein IDA-10.442
ceh-32Protein CEH-320.441
eya-1Protein EYA-10.439
attf-2Protein ATTF-20.432
lin-36Protein LIN-360.429
Y48E1A.1Protein Y48E1A.10.429
his-61Protein HIS-610.426
hlh-1Protein HLH-10.426
daf-11Protein DAF-110.419
unc-83Protein UNC-830.416
lin-17Protein LIN-170.416
plk-3Protein PLK-30.407
mls-2Protein MLS-20.403
pbrm-1Protein PBRM-10.403
sams-4Protein SAMS-40.400
lin-29Protein LIN-290.399
F40F4.7Protein F40F4.70.398
imb-2Protein IMB-20.397
unc-62Protein UNC-620.388
isw-1Protein ISW-10.385
mat-3Protein MAT-30.383
T09B4.5Protein T09B4.50.382
tag-260Protein TAG-2600.377
his-38Protein HIS-380.377
rsp-1Protein RSP-10.375
klp-16Protein KLP-160.374
myo-3Protein MYO-30.374
lin-66Protein LIN-660.371
cpt-1Protein CPT-10.367
sur-2Protein SUR-20.365
his-3Protein HIS-30.361
rpn-1Protein RPN-10.360
unc-73Protein UNC-730.357
ogt-1Protein OGT-10.357
zyg-9Protein ZYG-90.356
rpt-3Protein RPT-30.355
emb-5Protein EMB-50.354
mix-1Protein MIX-10.353
apr-1Protein APR-10.353
sma-9Protein SMA-90.352
lin-2Protein LIN-20.352
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism