The network for 'nephron tubule morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nephron tubule morphogenesis

The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.

NameDescriptionProbabilityFunc Analog Organism
osr2odd-skipped related 2 (Drosophila)0.987
pax2apaired box gene 2a0.971
shhasonic hedgehog a0.960
foxd3forkhead box D30.939
wt1bwilms tumor 1b0.934
bmp2bbone morphogenetic protein 2b0.906
wt1awilms tumor 1a0.852
hey1hairy/enhancer-of-split related with YRPW motif 10.840
notch3notch homolog 30.836
cdh2cadherin 2, neuronal0.824
wnt5bwingless-type MMTV integration site family, member 5b0.808
tbx1T-box 10.787
bmp2abone morphogenetic protein 2a0.772
hoxd4ahomeo box D4a0.772
chdchordin0.737
hoxa9bhomeo box A9b0.712
bmp4bone morphogenetic protein 40.705
spry1sprouty homolog 1 (Drosophila)0.700
myod1myogenic differentiation 10.699
eya1eyes absent homolog 10.692
wnt1wingless-type MMTV integration site family, member 10.678
wnt2bawingless-type MMTV integration site family, member 2Ba0.655
fgf10afibroblast growth factor 10a0.650
lef1lymphocyte enhancer binding factor 10.647
etv2ets variant gene 20.641
prdm1aPR domain containing 1a, with ZNF domain0.599
nkx3.2NK3 homeobox 20.598
gyltl1bglycosyltransferase-like 1b0.597
robo3roundabout homolog 30.596
hoxa9ahomeo box A9a0.588
tbx16T-box gene 160.572
osr1odd-skipped related 1 (Drosophila)0.568
hoxd10ahomeo box D10a0.545
hoxa13bhomeo box A13b0.532
gbx2gastrulation brain homeo box 20.530
hmx2H6 family homeobox 20.524
itga3bintegrin, alpha 3b0.510
sesn1sestrin 10.493
lhx1aLIM homeobox 1a0.484
hoxd11ahomeo box D11a0.483
hoxa10bhomeo box A10b0.479
wnt10awingless-type MMTV integration site family, member 10a0.465
fgf8afibroblast growth factor 8 a0.460
twist1btwist1b0.453
sim1asingle-minded homolog 1a (Drosophila)0.452
hhiphedgehog interacting protein0.424
hoxa11ahomeo box A11a0.418
vegfaavascular endothelial growth factor Aa0.417
tbx18T-box 180.408
mecomMDS1 and EVI1 complex locus0.402
notch1anotch homolog 1a0.395
itgavintegrin, alpha V0.391
jag2jagged 20.389
twist1atwist1a0.372
tll1tolloid-like 10.372
hoxd13ahomeo box D13a0.371
gdnfglial cell derived neurotrophic factor0.363
aldh1a2aldehyde dehydrogenase 1 family, member A20.361
pcdh8protocadherin 80.356
fgf3fibroblast growth factor 30.350
hoxd12ahomeo box D12a0.347
six4bsine oculis homeobox homolog 4b0.346
bmp1abone morphogenetic protein 1a0.340
ism1isthmin 10.338
rfx2regulatory factor X, 2 (influences HLA class II expression)0.337
hoxa13ahomeo box A13a0.330
lrrc50leucine rich repeat containing 500.328
myf5myogenic factor 50.323
mibmind bomb0.319
hnf1bbHNF1 homeobox Bb0.316
wnt2bbwingless-type MMTV integration site family, member 2Bb0.310
antxr1anthrax toxin receptor 10.309
prrx1bpaired related homeobox 1b0.299
snai1asnail homolog 1a (Drosophila)0.295
aplnrbapelin receptor b0.281
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.281
jag1bjagged 1b0.276
ptgs1prostaglandin-endoperoxide synthase 10.275
wnt3awingless-type MMTV integration site family, member 3A0.271
eng1aengrailed 1a0.259
wnt4awingless-type MMTV integration site family, member 4a0.258
pea3ETS-domain transcription factor pea30.257
six4asine oculis homeobox homolog 4a0.257
twist3twist30.253
hoxd9ahomeo box D9a0.252
flrfleer0.251
sox10SRY-box containing gene 100.247
evx1even-skipped homeobox 10.234
runx2brunt-related transcription factor 2b0.228
pcdh17protocadherin 170.222
msxbmuscle segment homeobox B0.221
hmx1H6 homeo box 10.213
igfbp3insulin-like growth factor binding protein 30.210
evx2even-skipped homeobox 20.206
tbx5aT-box 5a0.206
wnt3wingless-type MMTV integration site family, member 30.206
foxo3bforkhead box O3b0.202
six2asine oculis-related homeobox 2a0.200
per2period homolog 2 (Drosophila)0.196
mitfamicrophthalmia-associated transcription factor a0.196
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
wgwingless1.000
cicubitus interruptus0.999
hhhedgehog0.999
hthhomothorax0.974
HLHm7E(spl) region transcript m70.967
enengrailed0.964
HLHmdeltaE(spl) region transcript mdelta0.949
E(spl)Enhancer of split0.870
bowlbrother of odd with entrails limited0.858
SerSerrate0.854
kniknirps0.824
dsdachsous0.809
argosCG4531 gene product from transcript CG4531-RA0.805
vgvestigial0.796
DfdDeformed0.786
EgfrEpidermal growth factor receptor0.773
emcextra macrochaetae0.692
osoutstretched0.604
HLHmgammaE(spl) region transcript mgamma0.580
fngfringe0.573
m2E(spl) region transcript m20.536
HLHmbetaE(spl) region transcript mbeta0.500
oddodd skipped0.483
bibbig brain0.462
UbxUltrabithorax0.459
TomTwin of m40.453
DadDaughters against dpp0.425
panpangolin0.403
atoatonal0.391
HLHm3E(spl) region transcript m30.390
tshteashirt0.371
Fas2Fasciclin 20.365
ssspineless0.357
slp1sloppy paired 10.340
prosprospero0.339
nocno ocelli0.337
gtgiant0.333
HLHm5E(spl) region transcript m50.330
MadMothers against dpp0.323
opaodd paired0.314
ftfat0.311
tuptailup0.241
kluklumpfuss0.240
dppdecapentaplegic0.230
eyaeyes absent0.225
gcmglial cells missing0.222
scscute0.221
AntpAntennapedia0.215
brkbrinker0.210
runrunt0.207
sbbscribbler0.207
snasnail0.203
alaristaless0.203
bibifid0.200
malphaE(spl) region transcript malpha0.195
sogshort gastrulation0.189
ococelliless0.181
shnschnurri0.179
sosine oculis0.177
DllDistal-less0.174
emsempty spiracles0.172
egeagle0.169
putpunt0.165
dacdachshund0.164
discodisconnected0.162
18w18 wheeler0.162
JIL-1CG6297 gene product from transcript CG6297-RA0.160
araaraucan0.154
nkdnaked cuticle0.151
sggshaggy0.150
kuzkuzbanian0.150
bynbrachyenteron0.147
gbbglass bottom boat0.139
Nrx-IVNeurexin IV0.137
witwishful thinking0.133
CG3563CG3563 gene product from transcript CG3563-RA0.133
btlbreathless0.130
invinvected0.129
bab2CG9102 gene product from transcript CG9102-RA0.129
fjfour-jointed0.129
grogroucho0.121
aopanterior open0.116
eveeven skipped0.115
frafrazzled0.114
porporcupine0.114
taptarget of Poxn0.111
exexpanded0.110
tlltailless0.109
abd-Aabdominal A0.108
hkbhuckebein0.108
tratransformer0.104
eyeyeless0.104
mbcmyoblast city0.096
nubnubbin0.095
dydusky0.094
exdextradenticle0.093
B-H1BarH10.093
lablabial0.092
twitwist0.092
l(2)gllethal (2) giant larvae0.092
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 21.000
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.954
FSTL1follistatin-like 10.876
NR4A1nuclear receptor subfamily 4, group A, member 10.876
EGR1early growth response 10.874
FGF10fibroblast growth factor 100.793
FGF1fibroblast growth factor 1 (acidic)0.789
KLHL3kelch-like 3 (Drosophila)0.782
VEGFAvascular endothelial growth factor A0.769
EGR3early growth response 30.717
WNK4WNK lysine deficient protein kinase 40.700
BMPR1Abone morphogenetic protein receptor, type IA0.688
KLHL12kelch-like 12 (Drosophila)0.624
CUL3cullin 30.619
DAPK1death-associated protein kinase 10.601
EGR2early growth response 20.573
MEIS1Meis homeobox 10.567
PKD2polycystic kidney disease 2 (autosomal dominant)0.480
MEOX1mesenchyme homeobox 10.425
PKD1polycystic kidney disease 1 (autosomal dominant)0.402
MEIS2Meis homeobox 20.398
FGFR1fibroblast growth factor receptor 10.337
FGF8fibroblast growth factor 8 (androgen-induced)0.306
NKX2-1NK2 homeobox 10.292
SKILSKI-like oncogene0.284
TSC22D4TSC22 domain family, member 40.257
SMAD3SMAD family member 30.221
ADAM17ADAM metallopeptidase domain 170.182
PJA1praja ring finger 10.159
FGF4fibroblast growth factor 40.152
DVL3dishevelled, dsh homolog 3 (Drosophila)0.146
PGFplacental growth factor0.145
MSNmoesin0.144
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.142
KLHL2kelch-like 2, Mayven (Drosophila)0.142
WNT1wingless-type MMTV integration site family, member 10.140
SMAD2SMAD family member 20.140
GLIS2GLIS family zinc finger 20.129
HOXB5homeobox B50.119
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.117
FGF3fibroblast growth factor 30.117
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.109
COL2A1collagen, type II, alpha 10.101
MAGED2melanoma antigen family D, 20.100
FGF18fibroblast growth factor 180.099
HOXA10homeobox A100.097
NRP1neuropilin 10.095
TAOK1TAO kinase 10.094
BCL2L1BCL2-like 10.091
NR4A2nuclear receptor subfamily 4, group A, member 20.087
MDM2Mdm2 p53 binding protein homolog (mouse)0.083
BMP7bone morphogenetic protein 70.083
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.074
PAX8paired box 80.073
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.062
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.060
NR4A3nuclear receptor subfamily 4, group A, member 30.057
FOSFBJ murine osteosarcoma viral oncogene homolog0.051
TIMP3TIMP metallopeptidase inhibitor 30.050
TP53tumor protein p530.048
PAX3paired box 30.045
SOX1SRY (sex determining region Y)-box 10.044
TGFBR1transforming growth factor, beta receptor 10.042
SFRP1secreted frizzled-related protein 10.039
NOTCH1notch 10.038
IER2immediate early response 20.038
ENGendoglin0.037
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.036
FGFR3fibroblast growth factor receptor 30.033
LBX1ladybird homeobox 10.033
MDFIMyoD family inhibitor0.033
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.031
HES2hairy and enhancer of split 2 (Drosophila)0.027
CLDN4claudin 40.027
HOXB6homeobox B60.026
HOXA11homeobox A110.026
TRPC1transient receptor potential cation channel, subfamily C, member 10.026
ZNF331zinc finger protein 3310.025
HOXD13homeobox D130.025
HNF1AHNF1 homeobox A0.025
HMGA2high mobility group AT-hook 20.024
NFE2L2nuclear factor (erythroid-derived 2)-like 20.024
FOXA2forkhead box A20.023
BMP2bone morphogenetic protein 20.023
GDNFglial cell derived neurotrophic factor0.022
FGF7fibroblast growth factor 70.021
BBS1Bardet-Biedl syndrome 10.021
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.021
TAL1T-cell acute lymphocytic leukemia 10.021
SIM2single-minded homolog 2 (Drosophila)0.021
ZFYVE9zinc finger, FYVE domain containing 90.021
INHBBinhibin, beta B0.021
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.020
PAX7paired box 70.020
FOXL1forkhead box L10.019
SKIv-ski sarcoma viral oncogene homolog (avian)0.019
PAX2paired box 20.019
BHLHE40basic helix-loop-helix family, member e400.018
SLC3A2solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 20.018
PTPRBprotein tyrosine phosphatase, receptor type, B0.018
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax2paired box gene 21.000
Fgfr2fibroblast growth factor receptor 21.000
Gli3GLI-Kruppel family member GLI31.000
Pax8paired box gene 81.000
Fgf8fibroblast growth factor 81.000
Wt1Wilms tumor 1 homolog1.000
Gdnfglial cell line derived neurotrophic factor1.000
Foxc1forkhead box C11.000
Bmp4bone morphogenetic protein 41.000
Pax3paired box gene 31.000
Bcl2B-cell leukemia/lymphoma 21.000
Pitx2paired-like homeodomain transcription factor 21.000
Lhx1LIM homeobox protein 10.999
Hand2heart and neural crest derivatives expressed transcript 20.999
Ctnnb1catenin (cadherin associated protein), beta 10.999
Otx2orthodenticle homolog 2 (Drosophila)0.999
Rargretinoic acid receptor, gamma0.999
Hoxd11homeobox D110.999
Hand1heart and neural crest derivatives expressed transcript 10.998
Emx2empty spiracles homolog 2 (Drosophila)0.998
Vegfavascular endothelial growth factor A0.998
Retret proto-oncogene0.997
Smosmoothened homolog (Drosophila)0.997
Hoxd3homeobox D30.995
Dlx5distal-less homeobox 50.995
Tcf21transcription factor 210.995
Hoxa11homeobox A110.994
Msx1homeobox, msh-like 10.994
Tbx1T-box 10.994
Hoxb6homeobox B60.993
Fgfr1fibroblast growth factor receptor 10.992
Gli2GLI-Kruppel family member GLI20.992
Foxc2forkhead box C20.992
Nognoggin0.991
Rararetinoic acid receptor, alpha0.990
Hoxd9homeobox D90.987
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.987
Smad6MAD homolog 6 (Drosophila)0.987
Hoxc8homeobox C80.986
Hoxa2homeobox A20.985
Pbx1pre B-cell leukemia transcription factor 10.984
Isl1ISL1 transcription factor, LIM/homeodomain0.984
Sox9SRY-box containing gene 90.981
Tbx2T-box 20.980
Eya1eyes absent 1 homolog (Drosophila)0.979
Tcfap2atranscription factor AP-2, alpha0.977
Nr5a1nuclear receptor subfamily 5, group A, member 10.977
Tgfb2transforming growth factor, beta 20.974
Rarbretinoic acid receptor, beta0.974
Hoxa1homeobox A10.973
Hoxc5homeobox C50.972
Ror2receptor tyrosine kinase-like orphan receptor 20.971
Fgf10fibroblast growth factor 100.968
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.963
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.962
Hoxd4homeobox D40.962
Gbx2gastrulation brain homeobox 20.962
Lmx1bLIM homeobox transcription factor 1 beta0.961
Rxraretinoid X receptor alpha0.954
Otx1orthodenticle homolog 1 (Drosophila)0.952
Nkx2-1NK2 homeobox 10.949
Hoxb3homeobox B30.947
Nodalnodal0.941
Hoxa3homeobox A30.941
Hoxa9homeobox A90.941
Pkd1polycystic kidney disease 1 homolog0.940
Bmp7bone morphogenetic protein 70.939
Hoxa10homeobox A100.939
Hes1hairy and enhancer of split 1 (Drosophila)0.934
Smad3MAD homolog 3 (Drosophila)0.932
Wnt6wingless-related MMTV integration site 60.931
Wnt4wingless-related MMTV integration site 40.923
Meox2mesenchyme homeobox 20.922
Prrx1paired related homeobox 10.919
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.919
Ren1renin 1 structural0.908
Gata4GATA binding protein 40.908
Lhx3LIM homeobox protein 30.901
Msx2homeobox, msh-like 20.898
Dkk1dickkopf homolog 1 (Xenopus laevis)0.898
Hoxb5homeobox B50.898
Ednraendothelin receptor type A0.894
Hoxd13homeobox D130.889
Snai1snail homolog 1 (Drosophila)0.889
Bnc1basonuclin 10.885
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.882
Gata6GATA binding protein 60.877
Flt4FMS-like tyrosine kinase 40.877
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.872
Ptk7PTK7 protein tyrosine kinase 70.865
Tbx3T-box 30.862
Lmx1aLIM homeobox transcription factor 1 alpha0.857
Hoxc6homeobox C60.857
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.853
Wnt5awingless-related MMTV integration site 5A0.848
Ascl1achaete-scute complex homolog 1 (Drosophila)0.847
En1engrailed 10.844
Gscgoosecoid homeobox0.838
Acvr1activin A receptor, type 10.836
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism