The network for 'positive regulation of reproductive process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of reproductive process

Any process that activates or increases the frequency, rate or extent of reproductive process.

NameDescriptionProbabilityFunc Analog Organism
sim1asingle-minded homolog 1a (Drosophila)0.261
pea3ETS-domain transcription factor pea30.237
gdf9growth differentiation factor 90.207
robo1roundabout homolog 10.180
wt1awilms tumor 1a0.176
si:ch211-14a17.7si:ch211-14a17.70.176
pomcaproopiomelanocortin a0.169
inhainhibin, alpha0.158
nr2f6anuclear receptor subfamily 2, group F, member 6a0.141
sox5SRY-box containing gene 50.123
tbx1T-box 10.120
p4ha2procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 20.108
zp2.2zona pellucida glycoprotein 2.20.095
arpc5bactin related protein 2/3 complex, subunit 5B0.089
LOC100535118l-rhamnose-binding lectin CSL3-like0.087
bmp15bone morphogenetic protein 150.086
wu:fi38e01wu:fi38e010.077
wu:fi42e03wu:fi42e030.073
znf148zinc finger protein 1480.073
ncor1nuclear receptor co-repressor 10.073
zgc:64040zgc:640400.069
cyp19a1acytochrome P450, family 19, subfamily A, polypeptide 1a0.069
tmpoathymopoietin a0.068
skianuclear oncoprotein skia0.068
ppardbperoxisome proliferator-activated receptor delta b0.066
spry4sprouty (Drosophila) homolog 40.065
rargaretinoic acid receptor gamma a0.063
glcebglucuronyl C5-epimerase b0.063
zp3a.2zona pellucida glycoprotein 3a.20.063
aim1aabsent in melanoma 1a0.059
arpc5aactin related protein 2/3 complex, subunit 5A0.058
slit2slit (Drosophila) homolog 20.057
oc90otoconin 900.057
renrenin0.055
zpcxzona pellucida protein C0.055
spawsouthpaw0.053
hnf1bbHNF1 homeobox Bb0.053
tmem88atransmembrane protein 88 a0.051
zgc:110307zgc:1103070.051
cd82aCD82 antigen, a0.048
arpc4actin related protein 2/3 complex, subunit 40.048
shdbSrc homology 2 domain containing transforming protein D, b0.046
itga3bintegrin, alpha 3b0.046
cacnb4acalcium channel, voltage-dependent, beta 4a subunit0.046
pcsk5bproprotein convertase subtilisin/kexin type 5b0.046
sept6septin 60.045
sept2septin 20.045
LOC100333730l-rhamnose-binding lectin CSL1-like0.045
zgc:63587zgc:635870.044
zgc:171779zgc:1717790.044
chd7chromodomain helicase DNA binding protein 70.044
myl9lmyosin, light polypeptide 9, like0.044
fzd9bfrizzled homolog 9b0.044
sb:eu2468sb:eu24680.044
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.043
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.043
smosmoothened homolog (Drosophila)0.042
rtcd1RNA terminal phosphate cyclase domain 10.042
spry2sprouty homolog 20.041
rasl11bRAS-like, family 11, member B0.041
LOC100004296novel protein similar to murine T brachyury (T)0.041
dhrs3bdehydrogenase/reductase (SDR family) member 3b0.040
hoxa13ahomeo box A13a0.040
vgll4lvestigial like 4 like0.040
ptch2patched 20.040
mapk8bmitogen-activated protein kinase 8b0.040
ext2exostoses (multiple) 20.038
LOC100538023hypothetical protein LOC1005380230.038
LOC100331431hypothetical protein LOC1003314310.038
osr2odd-skipped related 2 (Drosophila)0.037
dvr1decapentaplegic and Vg-related 10.037
axin2axin 2 (conductin, axil)0.037
si:ch211-226m16.2si:ch211-226m16.20.037
fzd7afrizzled homolog 7a0.037
zgc:111868zgc:1118680.036
mapk6mitogen-activated protein kinase 60.036
ccbe1collagen and calcium binding EGF domains 10.036
id1inhibitor of DNA binding 10.035
wu:fi34b01wu:fi34b010.035
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.035
LOC100332505hypothetical protein LOC1003325050.035
twist3twist30.035
si:ch211-57k11.10si:ch211-57k11.100.035
tgfb1atransforming growth factor, beta 1a0.035
gscgoosecoid0.035
wnt2bawingless-type MMTV integration site family, member 2Ba0.035
smad1MAD homolog 1 (Drosophila)0.035
LOC100332822hypothetical protein LOC1003328220.035
nova2neuro-oncological ventral antigen 20.035
LOC100332229histone H2A type 1-A-like0.035
prkab1bprotein kinase, AMP-activated, beta 1 non-catalytic subunit, b0.034
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.034
zgc:171818zgc:1718180.034
epha2eph receptor A20.033
kirrelbkin of IRRE like b0.033
zgc:171977zgc:1719770.033
rab28RAB28, member RAS oncogene family0.033
msnbmoesin b0.033
nrip1bnuclear receptor interacting protein 1b0.033
si:dkeyp-68f6.1si:dkeyp-68f6.10.033
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
nejnejire0.655
RbfRetinoblastoma-family protein0.165
Akt1CG4006 gene product from transcript CG4006-RA0.092
Ras85DRas oncogene at 85D0.072
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.060
Atg18Autophagy-specific gene 180.057
scylscylla0.044
DpDP transcription factor0.040
skdskuld0.029
rinrasputin0.023
mip120Myb-interacting protein 1200.020
ttvtout-velu0.020
sxcsuper sex combs0.019
E2fE2F transcription factor0.018
PtenCG5671 gene product from transcript CG5671-RB0.017
simsingle-minded0.015
sharkSrc homology 2, ankyrin repeat, tyrosine kinase0.015
trxtrithorax0.015
simjsimjang0.014
myoglianinCG1838 gene product from transcript CG1838-RD0.014
Pi3K59FPhosphotidylinositol 3 kinase 59F0.013
SplySphingosine-1-phosphate lyase0.011
coscosta0.011
Pi3K21BCG2699 gene product from transcript CG2699-RA0.011
cicubitus interruptus0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMAD7SMAD family member 70.591
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.477
FKBP1AFK506 binding protein 1A, 12kDa0.298
E2F6E2F transcription factor 60.187
POU5F1POU class 5 homeobox 10.186
TGFB1transforming growth factor, beta 10.181
PAX3paired box 30.157
BMP2bone morphogenetic protein 20.155
PSEN2presenilin 2 (Alzheimer disease 4)0.144
POU3F2POU class 3 homeobox 20.141
E2F4E2F transcription factor 4, p107/p130-binding0.095
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.091
GDF5growth differentiation factor 50.082
TFDP1transcription factor Dp-10.071
LRRK2leucine-rich repeat kinase 20.068
MAPK14mitogen-activated protein kinase 140.067
CREBBPCREB binding protein0.062
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.057
ENGendoglin0.049
LIN9lin-9 homolog (C. elegans)0.045
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.043
SMAD3SMAD family member 30.038
RB1retinoblastoma 10.038
ARID1BAT rich interactive domain 1B (SWI1-like)0.036
SMURF2SMAD specific E3 ubiquitin protein ligase 20.036
AKAP11A kinase (PRKA) anchor protein 110.031
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.031
ZMYND11zinc finger, MYND-type containing 110.030
PLAURplasminogen activator, urokinase receptor0.027
BMPR1Abone morphogenetic protein receptor, type IA0.026
PLAUplasminogen activator, urokinase0.023
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.022
PROX1prospero homeobox 10.021
E2F1E2F transcription factor 10.021
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.021
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.021
SMAD1SMAD family member 10.019
SMAD2SMAD family member 20.019
PLATplasminogen activator, tissue0.018
DVL3dishevelled, dsh homolog 3 (Drosophila)0.018
TGFB3transforming growth factor, beta 30.018
NCOA6nuclear receptor coactivator 60.017
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.017
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.017
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.017
ZYXzyxin0.016
KAT2BK(lysine) acetyltransferase 2B0.016
SMAD4SMAD family member 40.016
PRKG1protein kinase, cGMP-dependent, type I0.015
FSTL1follistatin-like 10.014
QKIquaking homolog, KH domain RNA binding (mouse)0.014
SMAD5SMAD family member 50.014
ATF2activating transcription factor 20.014
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.014
CUX1cut-like homeobox 10.013
MAPK15mitogen-activated protein kinase 150.013
MYBL2v-myb myeloblastosis viral oncogene homolog (avian)-like 20.013
AXIN1axin 10.013
TGFBR1transforming growth factor, beta receptor 10.012
DVL1dishevelled, dsh homolog 1 (Drosophila)0.012
WASLWiskott-Aldrich syndrome-like0.012
NR0B1nuclear receptor subfamily 0, group B, member 10.012
PRKACBprotein kinase, cAMP-dependent, catalytic, beta0.011
AKIP1A kinase (PRKA) interacting protein 10.011
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.010
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Amhr2anti-Mullerian hormone type 2 receptor0.915
Gata4GATA binding protein 40.770
Fshrfollicle stimulating hormone receptor0.594
Inhbainhibin beta-A0.586
Kiss1KiSS-1 metastasis-suppressor0.550
Fgfr2fibroblast growth factor receptor 20.547
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.526
Lhcgrluteinizing hormone/choriogonadotropin receptor0.441
Arid1bAT rich interactive domain 1B (SWI-like)0.439
Smad4MAD homolog 4 (Drosophila)0.414
Apcadenomatosis polyposis coli0.384
Smad3MAD homolog 3 (Drosophila)0.356
Esr1estrogen receptor 1 (alpha)0.285
Egr1early growth response 10.275
Nr5a1nuclear receptor subfamily 5, group A, member 10.253
Raver2ribonucleoprotein, PTB-binding 20.243
Ptgs2prostaglandin-endoperoxide synthase 20.241
Nos1nitric oxide synthase 1, neuronal0.153
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.121
Fstfollistatin0.120
Arid1aAT rich interactive domain 1A (SWI-like)0.111
Gli3GLI-Kruppel family member GLI30.110
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.109
Nab2Ngfi-A binding protein 20.105
Itgb1integrin beta 1 (fibronectin receptor beta)0.091
Hoxd10homeobox D100.091
Gnrh1gonadotropin releasing hormone 10.078
E2f1E2F transcription factor 10.077
Dhhdesert hedgehog0.076
Adra1badrenergic receptor, alpha 1b0.075
Dlg4discs, large homolog 4 (Drosophila)0.074
Ptpn11protein tyrosine phosphatase, non-receptor type 110.072
Acvr2aactivin receptor IIA0.068
Nr0b1nuclear receptor subfamily 0, group B, member 10.068
Egr2early growth response 20.066
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.066
Inhbbinhibin beta-B0.065
Vaspvasodilator-stimulated phosphoprotein0.064
Mitfmicrophthalmia-associated transcription factor0.063
Kiss1rKISS1 receptor0.061
Lhx9LIM homeobox protein 90.061
Irs2insulin receptor substrate 20.060
Edn1endothelin 10.059
Lhx3LIM homeobox protein 30.053
Prkchprotein kinase C, eta0.053
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.053
Nf1neurofibromatosis 10.052
Utf1undifferentiated embryonic cell transcription factor 10.050
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.049
E2f5E2F transcription factor 50.048
Kitkit oncogene0.046
Inhainhibin alpha0.046
Spry4sprouty homolog 4 (Drosophila)0.045
Arandrogen receptor0.045
Plekha5pleckstrin homology domain containing, family A member 50.045
Mrpl3mitochondrial ribosomal protein L30.043
Slc30a3solute carrier family 30 (zinc transporter), member 30.038
Gata5GATA binding protein 50.038
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.038
Plxna4plexin A40.036
Sh3kbp1SH3-domain kinase binding protein 10.034
Nhlh2nescient helix loop helix 20.034
Mn1meningioma 10.033
Kcnab3potassium voltage-gated channel, shaker-related subfamily, beta member 30.032
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.032
Pcdha10protocadherin alpha 100.029
Flt1FMS-like tyrosine kinase 10.029
FosbFBJ osteosarcoma oncogene B0.029
FosFBJ osteosarcoma oncogene0.028
Tcfap2atranscription factor AP-2, alpha0.028
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.028
Homer1homer homolog 1 (Drosophila)0.028
Sox7SRY-box containing gene 70.028
Prkar2bprotein kinase, cAMP dependent regulatory, type II beta0.028
Rassf5Ras association (RalGDS/AF-6) domain family member 50.028
Gfra3glial cell line derived neurotrophic factor family receptor alpha 30.027
Bcar1breast cancer anti-estrogen resistance 10.027
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.027
Fgfr3fibroblast growth factor receptor 30.027
Plxna1plexin A10.026
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.026
Epb4.1l2erythrocyte protein band 4.1-like 20.026
Spry2sprouty homolog 2 (Drosophila)0.026
Drd2dopamine receptor D20.026
Parp1poly (ADP-ribose) polymerase family, member 10.026
Smpd3sphingomyelin phosphodiesterase 3, neutral0.025
Arnt2aryl hydrocarbon receptor nuclear translocator 20.025
Sema3csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C0.025
Epas1endothelial PAS domain protein 10.025
Adora2aadenosine A2a receptor0.025
Insrinsulin receptor0.025
Pde3aphosphodiesterase 3A, cGMP inhibited0.025
Nt5e5' nucleotidase, ecto0.025
Ipo5importin 50.025
Pa2g4proliferation-associated 2G40.024
Map3k11mitogen-activated protein kinase kinase kinase 110.024
Gli2GLI-Kruppel family member GLI20.024
Mknk2MAP kinase-interacting serine/threonine kinase 20.023
Atad3aATPase family, AAA domain containing 3A0.023
SrcRous sarcoma oncogene0.023
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SWI1Swi1p0.246
SNF5Snf5p0.171
SLT2Slt2p0.080
GLN3Gln3p0.067
BEM3Bem3p0.054
MOB1Mob1p0.054
HXT3Hxt3p0.043
MIG2Mig2p0.042
HAL5Hal5p0.040
YPL014Whypothetical protein0.039
YKR075Chypothetical protein0.036
ASF2Asf2p0.036
MOT1Mot1p0.035
PIB2Pib2p0.029
MIG3Mig3p0.027
STE11Ste11p0.026
MIG1Mig1p0.024
RGS2Rgs2p0.023
ROX1Rox1p0.023
SSK2Ssk2p0.022
RGD1Rgd1p0.022
GAT2Gat2p0.021
RTG3Rtg3p0.021
VID24Vid24p0.020
VAC7Vac7p0.019
GIP2Gip2p0.019
YLR297Whypothetical protein0.019
NUP157Nup157p0.018
SFL1Sfl1p0.018
SBE22Sbe22p0.018
LYS5Lys5p0.018
YGR035Chypothetical protein0.017
CAT8Cat8p0.017
SNF2Snf2p0.017
MSN2Msn2p0.016
AFT1Aft1p0.015
SWP82Swp82p0.015
SUT1Sut1p0.015
SMP1Smp1p0.015
PHM8Phm8p0.015
TRA1Tra1p0.015
PHO12Pho12p0.014
FPS1Fps1p0.014
CSR2Csr2p0.013
YPR157Whypothetical protein0.013
NUP170Nup170p0.013
IXR1Ixr1p0.013
HRK1Hrk1p0.013
NTO1Nto1p0.012
TPO2Tpo2p0.012
MSG5Msg5p0.012
RMA1Rma1p0.012
MOT3Mot3p0.012
KIC1Kic1p0.011
CUP9Cup9p0.011
EAR1Ear1p0.011
HHF2Hhf2p0.011
FAA2Faa2p0.010
YAR068Whypothetical protein0.010
PSK2Psk2p0.010
WAR1War1p0.010
SWI5Swi5p0.010
SRD1Srd1p0.010
PTR3Ptr3p0.010