The network for 'lateral line development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lateral line development

The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.

NameDescriptionProbabilityFunc Analog Organism
eya1eyes absent homolog 10.999
hoxc4ahomeo box C4a0.963
hoxb8ahomeo box B8a0.947
hoxc8ahomeo box C8a0.933
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.895
lef1lymphocyte enhancer binding factor 10.862
gria4aglutamate receptor, ionotropic, AMPA 4a0.844
hoxb6ahomeo box B6a0.839
fgf10afibroblast growth factor 10a0.826
hoxb6bhomeo box B6b0.813
lmx1b.1LIM homeobox transcription factor 1, beta 10.811
alcamaactivated leukocyte cell adhesion molecule a0.804
wnt4awingless-type MMTV integration site family, member 4a0.802
atoh1aatonal homolog 1a0.801
fgf3fibroblast growth factor 30.800
metmet proto-oncogene (hepatocyte growth factor receptor)0.799
hoxd4ahomeo box D4a0.793
pcsk5aproprotein convertase subtilisin/kexin type 5a0.781
irx2airoquois homeobox protein 2, a0.779
epcamepithelial cell adhesion molecule0.771
scn1bbsodium channel, voltage-gated, type I, beta b0.758
hoxb3ahomeo box B3a0.719
wnt1wingless-type MMTV integration site family, member 10.684
cdh6cadherin 60.677
gria3bglutamate receptor, ionotrophic, AMPA 3b0.664
hoxb5ahomeo box B5a0.653
iclp1invariant chain-like protein 10.636
hmx3homeo box (H6 family) 30.632
sox10SRY-box containing gene 100.594
grhl2bgrainyhead-like 2b (Drosophila)0.592
hoxb5bhomeo box B5b0.584
cldn7bclaudin 7b0.582
cldnhclaudin h0.567
kal1aKallmann syndrome 1a sequence0.565
wnt11rwingless-type MMTV integration site family, member 11, related0.565
gbx2gastrulation brain homeo box 20.561
irx1airoquois homeobox protein 1, a0.547
hoxc6ahomeo box C6a0.546
cxcr4bchemokine (C-X-C motif), receptor 4b0.528
gperG protein-coupled estrogen receptor 10.504
rorbRAR-related orphan receptor B0.488
tcf7transcription factor 7 (T-cell specific, HMG-box)0.478
spint1aserine peptidase inhibitor, Kunitz type 1 a0.471
foxa1forkhead box A10.448
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.443
cldnbclaudin b0.437
axin2axin 2 (conductin, axil)0.424
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.396
hmx2H6 family homeobox 20.396
ca2carbonic anhydrase II0.385
epha7eph receptor A70.378
lmx1b.2LIM homeobox transcription factor 1, beta 20.370
fzd8afrizzled homolog 8a0.367
igf3insulin-like growth factor 30.366
vcanbversican b0.362
myo7aamyosin VIIAa0.360
spry1sprouty homolog 1 (Drosophila)0.359
six1bsine oculis homeobox homolog 1b0.351
myod1myogenic differentiation 10.342
dkk1bdickkopf 1b0.336
eng2bengrailed 2b0.333
ptgs2aprostaglandin-endoperoxide synthase 2a0.327
hoxa4ahomeo box A4a0.321
bdnfbrain-derived neurotrophic factor0.313
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.309
gria2aglutamate receptor, ionotropic, AMPA 2a0.304
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.298
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.296
pcsk2proprotein convertase subtilisin/kexin type 20.293
gria1aglutamate receptor, ionotropic, AMPA 1a0.293
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.281
jag2jagged 20.277
hoxd10ahomeo box D10a0.275
cxcr4achemokine (C-X-C motif) receptor 4a0.272
six4bsine oculis homeobox homolog 4b0.267
fgfr1afibroblast growth factor receptor 1a0.266
hoxa9ahomeo box A9a0.264
hoxa5ahomeo box A5a0.258
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.256
cntn2contactin 20.251
pcsk7proprotein convertase subtilisin/kexin type 70.246
rhoubras homolog gene family, member Ub0.246
irx1biroquois homeobox protein 1, b0.240
mbpmyelin basic protein0.226
neurog1neurogenin 10.226
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.222
ascl1aachaete-scute complex-like 1a (Drosophila)0.221
hoxb4ahomeo box B4a0.217
esrrgaestrogen-related receptor gamma a0.216
wnt7bawingless-type MMTV integration site family, member 7Ba0.216
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.213
pcsk1proprotein convertase subtilisin/kexin type 10.213
stat3signal transduction and activation of transcription 30.210
wnt3wingless-type MMTV integration site family, member 30.208
gdnfglial cell derived neurotrophic factor0.208
dab1bdisabled homolog 1b (Drosophila)0.203
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism