The network for 'regulation of cell matrix adhesion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell matrix adhesion

Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.

NameDescriptionProbabilityFunc Analog Organism
pdlim2PDZ and LIM domain 2 (mystique)0.983
limk1LIM domain kinase 10.947
pdlim3aPDZ and LIM domain 3a0.944
limk2LIM domain kinase 20.930
pdlim7PDZ and LIM domain 70.882
pdlim4PDZ and LIM domain 40.830
pdlim5PDZ and LIM domain 50.716
nf1aneurofibromin 1a0.682
lamb1alaminin, beta 1a0.593
ttnatitin a0.516
crb2acrumbs homolog 2a0.428
llgl2lethal giant larvae homolog 2 (Drosophila)0.372
pdlim3bPDZ and LIM domain 3b0.284
zbtb4zinc finger and BTB domain containing 40.252
gpm6aaglycoprotein M6Aa0.245
metmet proto-oncogene (hepatocyte growth factor receptor)0.241
nrp1aneuropilin 1a0.238
neo1neogenin 10.220
axin1axin 10.218
dlg4discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)0.209
nadl1.1neural adhesion molecule L1.10.208
wnt11wingless-type MMTV integration site family, member 110.199
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.197
mespamesoderm posterior a0.195
tuba8l3tubulin, alpha 8 like 30.193
actn2actinin, alpha 20.191
plod1aprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a0.182
hs3st3b1aheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a0.171
ckmacreatine kinase, muscle a0.166
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.159
vegfaavascular endothelial growth factor Aa0.148
csnk1g2acasein kinase 1, gamma 2a0.132
dnmt6DNA (cytosine-5-)-methyltransferase 60.132
robo3roundabout homolog 30.130
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.129
cdh2cadherin 2, neuronal0.129
dlg2discs, large (Drosophila) homolog 20.126
esamaendothelial cell adhesion molecule a0.125
kdrlkinase insert domain receptor like0.124
fmnl2aformin-like 2a0.123
pak2ap21 (CDKN1A)-activated kinase 2a0.122
ptprbprotein tyrosine phosphatase, receptor type, b0.121
cfl1cofilin 1 (non-muscle)0.117
mef2amyocyte enhancer factor 2a0.111
traf4atnf receptor-associated factor 4a0.111
wtipWilms tumor 1 interacting protein0.110
gli1GLI-Kruppel family member 10.110
trpm7transient receptor potential cation channel, subfamily M, member 70.108
nf1bneurofibromin 1b0.107
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.107
tfebtranscription factor EB0.105
ntn4netrin 40.104
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.104
fn1fibronectin 10.103
lrrtm2leucine rich repeat transmembrane neuronal 20.103
gng2guanine nucleotide binding protein (G protein), gamma 20.102
hspg2heparan sulfate proteoglycan 20.101
appbamyloid beta (A4) precursor protein b0.100
disc1disrupted in schizophrenia 10.097
adora2aaadenosine A2a receptor a0.093
gpm6bbglycoprotein M6Bb0.091
ntn2netrin 20.089
dpysl5bdihydropyrimidinase-like 5b0.088
slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.087
tpm4tropomyosin 40.087
rpe65bretinal pigment epithelium-specific protein 65b0.087
notch3notch homolog 30.086
pacsin3protein kinase C and casein kinase substrate in neurons 30.085
robo1roundabout homolog 10.085
abca5ATP-binding cassette, sub-family A (ABC1), member 50.081
bocbrother of CDO0.081
dpysl2bdihydropyrimidinase-like 2b0.081
hlxb9lbhomeo box HB9 like b0.081
notch1anotch homolog 1a0.081
hs6st1aheparan sulfate 6-O-sulfotransferase 1a0.080
fbn2bfibrillin 2b0.080
auts2autism susceptibility candidate 20.080
wnt1wingless-type MMTV integration site family, member 10.078
lgi1bleucine-rich, glioma inactivated 1b0.077
ldb3aLIM-domain binding factor 3a0.076
pdcd2programmed cell death 20.072
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.070
pgam2phosphoglycerate mutase 2 (muscle)0.068
tfe3atranscription factor binding to IGHM enhancer 3a0.067
npeppsaminopeptidase puromycin sensitive0.067
ptenaphosphatase and tensin homolog A0.067
tsc2tuberous sclerosis 20.066
cmlc1cardiac myosin light chain-10.066
gli2aGLI-Kruppel family member GLI2a0.065
tgfb3transforming growth factor, beta 30.064
tnnt2atroponin T2a, cardiac0.064
sheSrc homology 2 domain containing E0.064
ptk2.1protein tyrosine kinase 2a0.063
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
stcksteamer duck0.081
Akt1CG4006 gene product from transcript CG4006-RA0.075
mbcmyoblast city0.061
wbwing blister0.058
Cdc42CG12530 gene product from transcript CG12530-RA0.057
Atg1Autophagy-specific gene 10.047
Pi3K92ECG4141 gene product from transcript CG4141-RB0.043
chicoCG5686 gene product from transcript CG5686-RB0.040
Btk29ABtk family kinase at 29A0.036
RhoGEF2CG9635 gene product from transcript CG9635-RF0.030
Stat92ESignal-transducer and activator of transcription protein at 92E0.030
par-1CG8201 gene product from transcript CG8201-RA0.030
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.029
AblAbl tyrosine kinase0.028
dcodiscs overgrown0.027
Wnt5Wnt oncogene analog 50.025
S6kRPS6-p70-protein kinase0.025
rolsrolling pebbles0.023
Ptp69DProtein tyrosine phosphatase 69D0.023
PtenCG5671 gene product from transcript CG5671-RB0.022
cpacapping protein alpha0.021
DAAMDishevelled Associated Activator of Morphogenesis0.020
CG7145CG7145 gene product from transcript CG7145-RD0.019
Cad96CaCG10244 gene product from transcript CG10244-RA0.019
EphrinCG1862 gene product from transcript CG1862-RA0.019
CycDCyclin D0.018
trioCG18214 gene product from transcript CG18214-RA0.018
Sema-1aCG18405 gene product from transcript CG18405-RD0.018
InRInsulin-like receptor0.018
cdicenter divider0.017
Syx1ASyntaxin 1A0.017
G-oalpha47AG protein oalpha 47A0.016
AlkCG8250 gene product from transcript CG8250-RA0.016
CG9572CG9572 gene product from transcript CG9572-RA0.015
CapsCalcium activated protein for secretion0.015
CG30069CG30069 gene product from transcript CG30069-RA0.015
Tsc1CG6147 gene product from transcript CG6147-RA0.015
swshort wing0.015
DadDaughters against dpp0.015
p130CASCG1212 gene product from transcript CG1212-RA0.014
cindrCIN85 and CD2AP orthologue0.014
CG32528CG32528 gene product from transcript CG32528-RA0.014
reporeversed polarity0.014
LnkCG17367 gene product from transcript CG17367-RC0.014
zfh1Zn finger homeodomain 10.014
Pvf2PDGF- and VEGF-related factor 20.014
unc-104CG8566 gene product from transcript CG8566-RB0.014
Spn27ASerpin 27A0.014
MicalMolecule interacting with CasL0.014
MadMothers against dpp0.014
kirrekin of irre0.014
POSHPlenty of SH3s0.014
elavembryonic lethal abnormal vision0.013
stanstarry night0.013
HDAC4CG1770 gene product from transcript CG1770-RE0.013
GripGlutamate receptor binding protein0.013
DlicDynein light intermediate chain0.013
Pk61CProtein kinase 61C0.013
beta-Specbeta Spectrin0.013
AdarAdenosine deaminase acting on RNA0.013
CG14869CG14869 gene product from transcript CG14869-RB0.013
S6kIIRPS6-protein kinase-II0.013
betaInt-nubeta[nu] integrin0.013
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCAR1breast cancer anti-estrogen resistance 10.997
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.996
VEGFAvascular endothelial growth factor A0.989
PTK2PTK2 protein tyrosine kinase 20.985
EGFRepidermal growth factor receptor0.964
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.959
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.956
FHL2four and a half LIM domains 20.943
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.941
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.936
NCK2NCK adaptor protein 20.922
S100A8S100 calcium binding protein A80.920
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.918
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.866
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.858
MDM2Mdm2 p53 binding protein homolog (mouse)0.854
LIMS1LIM and senescent cell antigen-like domains 10.853
FN1fibronectin 10.810
PTPN1protein tyrosine phosphatase, non-receptor type 10.797
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.762
FYNFYN oncogene related to SRC, FGR, YES0.759
PTPN12protein tyrosine phosphatase, non-receptor type 120.755
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.737
NRP1neuropilin 10.712
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.682
PLAUplasminogen activator, urokinase0.660
HOXB5homeobox B50.654
S100A6S100 calcium binding protein A60.582
S100A9S100 calcium binding protein A90.581
DLG1discs, large homolog 1 (Drosophila)0.570
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.550
EPHA2EPH receptor A20.549
SMAD7SMAD family member 70.548
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.514
S100A4S100 calcium binding protein A40.509
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.471
MPDZmultiple PDZ domain protein0.437
ANGPT2angiopoietin 20.417
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.394
ABI2abl-interactor 20.392
METmet proto-oncogene (hepatocyte growth factor receptor)0.376
HOXA5homeobox A50.375
BMP2bone morphogenetic protein 20.375
CCND1cyclin D10.358
CTNND1catenin (cadherin-associated protein), delta 10.349
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.336
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.327
CDH5cadherin 5, type 2 (vascular endothelium)0.322
SMAD2SMAD family member 20.322
TM4SF1transmembrane 4 L six family member 10.317
PLAURplasminogen activator, urokinase receptor0.301
EPHA7EPH receptor A70.285
PTPRBprotein tyrosine phosphatase, receptor type, B0.279
SRCIN1SRC kinase signaling inhibitor 10.266
GRB7growth factor receptor-bound protein 70.266
ANXA2annexin A20.254
JUPjunction plakoglobin0.252
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.241
BBS10Bardet-Biedl syndrome 100.233
APCadenomatous polyposis coli0.233
S100A11S100 calcium binding protein A110.217
PDGFCplatelet derived growth factor C0.208
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.208
PDGFAplatelet-derived growth factor alpha polypeptide0.207
HOXB7homeobox B70.204
PTPN23protein tyrosine phosphatase, non-receptor type 230.203
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.198
BCL2L1BCL2-like 10.196
ZNF746zinc finger protein 7460.193
GBP3guanylate binding protein 30.185
TSC2tuberous sclerosis 20.175
S100BS100 calcium binding protein B0.172
F11RF11 receptor0.168
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.162
FKBP1AFK506 binding protein 1A, 12kDa0.161
HOXB6homeobox B60.150
SHC1SHC (Src homology 2 domain containing) transforming protein 10.150
PLATplasminogen activator, tissue0.147
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.139
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.138
AXIN1axin 10.135
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.134
HOXA10homeobox A100.134
HOXB3homeobox B30.132
GDF5growth differentiation factor 50.123
GAB1GRB2-associated binding protein 10.119
DTNAdystrobrevin, alpha0.115
PVRL2poliovirus receptor-related 2 (herpesvirus entry mediator B)0.114
HOXA1homeobox A10.113
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.111
TNCtenascin C0.108
LGALS1lectin, galactoside-binding, soluble, 10.108
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.105
DSG2desmoglein 20.105
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Sirpasignal-regulatory protein alpha0.014
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.012
Tgfb1transforming growth factor, beta 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism