The network for 'positive regulation of striated muscle tissue development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of striated muscle tissue development

Any process that activates or increases the frequency, rate or extent of striated muscle development.

NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.960
bmp4bone morphogenetic protein 40.903
fgf24fibroblast growth factor 240.758
gli1GLI-Kruppel family member 10.640
tbx5aT-box 5a0.603
mef2camyocyte enhancer factor 2ca0.523
aldh1a2aldehyde dehydrogenase 1 family, member A20.521
myod1myogenic differentiation 10.472
wnt11rwingless-type MMTV integration site family, member 11, related0.397
fgf3fibroblast growth factor 30.396
klf4aKruppel-like transcription factor 4a0.352
notch1bnotch homolog 1b0.341
hey2hairy/enhancer-of-split related with YRPW motif 20.335
fgfr1afibroblast growth factor receptor 1a0.317
tbx20T-box 200.290
igfbp3insulin-like growth factor binding protein 30.252
nkx2.5NK2 transcription factor related 50.249
has2hyaluronan synthase 20.241
cdh2cadherin 2, neuronal0.239
siah2lseven in absentia homolog 2 (Drosophila)-like0.231
bmp2bbone morphogenetic protein 2b0.231
coblcordon-bleu homolog (mouse)0.231
tbx18T-box 180.217
map2k4amitogen-activated protein kinase kinase 4a0.214
epha4aeph receptor A4a0.212
wnt4awingless-type MMTV integration site family, member 4a0.208
wnt3wingless-type MMTV integration site family, member 30.190
her5hairy-related 50.187
pcdh8protocadherin 80.175
mef2cbmyocyte enhancer factor 2cb0.171
myf5myogenic factor 50.168
atp1b2bATPase, Na+/K+ transporting, beta 2b polypeptide0.168
wnt10awingless-type MMTV integration site family, member 10a0.167
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.157
bocbrother of CDO0.153
fgf17fibroblast growth factor 170.152
wnt5bwingless-type MMTV integration site family, member 5b0.151
pcdh10bprotocadherin 10b0.150
mical2bmicrotubule associated monoxygenase, calponin and LIM domain containing 2b0.148
xirp1xin actin-binding repeat containing 10.145
mapk3mitogen-activated protein kinase 30.143
smyd1bSET and MYND domain containing 1b0.140
gbx2gastrulation brain homeo box 20.134
wnt1wingless-type MMTV integration site family, member 10.133
hmx4H6 family homeobox 40.129
her1hairy-related 10.129
sema3aasemaphorin 3aa0.122
tll1tolloid-like 10.122
efnb2aephrin B2a0.121
mapk1mitogen-activated protein kinase 10.118
kif23kinesin family member 230.117
spns2spinster homolog 2 (Drosophila)0.114
trpv4transient receptor potential cation channel, subfamily V, member 40.108
wnt8bwingless-type MMTV integration site family, member 8b0.105
tnnt2atroponin T2a, cardiac0.105
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.104
her7hairy and enhancer of split related-70.104
pdlim7PDZ and LIM domain 70.103
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.102
scube2signal peptide, CUB domain, EGF-like 20.102
crip2cysteine-rich protein 20.102
dnmt7DNA (cytosine-5-)-methyltransferase 70.099
wnt7aawingless-type MMTV integration site family, member 7Aa0.098
alcambactivated leukocyte cell adhesion molecule b0.096
aldh1a3aldehyde dehydrogenase 1 family, member A30.094
fgf8bfibroblast growth factor 8 b0.093
wif1wnt inhibitory factor 10.093
rarabretinoic acid receptor, alpha b0.093
wnt7bawingless-type MMTV integration site family, member 7Ba0.092
smad9MAD homolog 9 (Drosophila)0.090
zbtb4zinc finger and BTB domain containing 40.089
hsp90a.1heat shock protein 90-alpha 10.088
nanos3nanos homolog 30.087
efnb3bephrin B3b0.087
srfserum response factor0.087
hnf1baHNF1 homeobox Ba0.084
cmlc1cardiac myosin light chain-10.083
mibmind bomb0.082
adrb2aadrenergic receptor, beta 2a0.082
pkd2polycystic kidney disease 20.081
sox9aSRY-box containing gene 9a0.081
emx1empty spiracles homeobox 10.079
vcanaversican a0.077
foxo3bforkhead box O3b0.077
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.077
oepone-eyed pinhead0.076
arnt2aryl hydrocarbon receptor nuclear translocator 20.076
bdnfbrain-derived neurotrophic factor0.076
ptch2patched 20.076
crabp2acellular retinoic acid binding protein 2, a0.075
atoh1aatonal homolog 1a0.075
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.073
hand2heart and neural crest derivatives expressed transcript 20.070
gro1groucho 10.070
mtpmicrosomal triglyceride transfer protein0.070
ihhaIndian hedgehog homolog a0.070
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SRFserum response factor (c-fos serum response element-binding transcription factor)0.990
FGFR2fibroblast growth factor receptor 20.917
FGF1fibroblast growth factor 1 (acidic)0.504
FGF10fibroblast growth factor 100.460
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.460
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.392
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.356
BMPR1Abone morphogenetic protein receptor, type IA0.211
HDAC4histone deacetylase 40.136
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.073
NCOR2nuclear receptor corepressor 20.064
CLOCKclock homolog (mouse)0.050
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.046
CDK1cyclin-dependent kinase 10.043
FSTL1follistatin-like 10.043
NEDD4neural precursor cell expressed, developmentally down-regulated 40.038
TJP1tight junction protein 1 (zona occludens 1)0.036
CDK2cyclin-dependent kinase 20.033
BCL2L1BCL2-like 10.029
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.028
MAML1mastermind-like 1 (Drosophila)0.027
FGFR1fibroblast growth factor receptor 10.023
CCNE1cyclin E10.023
EP300E1A binding protein p3000.022
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.016
XIAPX-linked inhibitor of apoptosis0.015
TBX5T-box 50.015
ARRDC3arrestin domain containing 30.015
PLCG1phospholipase C, gamma 10.014
CCNA2cyclin A20.014
CCNB2cyclin B20.014
FGFR3fibroblast growth factor receptor 30.011
FGF2fibroblast growth factor 2 (basic)0.011
FRS2fibroblast growth factor receptor substrate 20.011
SIRT1sirtuin 10.011
HDAC9histone deacetylase 90.011
SPENspen homolog, transcriptional regulator (Drosophila)0.011
ATXN1Lataxin 1-like0.010
FGF7fibroblast growth factor 70.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tbx3T-box 30.999
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.999
Pitx2paired-like homeodomain transcription factor 20.984
Gata4GATA binding protein 40.979
Fgfr2fibroblast growth factor receptor 20.979
Shhsonic hedgehog0.977
Ntf3neurotrophin 30.969
Pax3paired box gene 30.915
Fgf10fibroblast growth factor 100.913
Fgf8fibroblast growth factor 80.883
Gli3GLI-Kruppel family member GLI30.865
Zfpm2zinc finger protein, multitype 20.859
Gli2GLI-Kruppel family member GLI20.850
Hand1heart and neural crest derivatives expressed transcript 10.813
Col13a1collagen, type XIII, alpha 10.790
Hand2heart and neural crest derivatives expressed transcript 20.747
Pitx1paired-like homeodomain transcription factor 10.733
Scn5asodium channel, voltage-gated, type V, alpha0.710
Sox2SRY-box containing gene 20.707
Ror2receptor tyrosine kinase-like orphan receptor 20.705
Msx1homeobox, msh-like 10.690
Tbx15T-box 150.676
Retret proto-oncogene0.600
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.560
Bmp4bone morphogenetic protein 40.556
Tbx1T-box 10.547
Otx2orthodenticle homolog 2 (Drosophila)0.521
Msx2homeobox, msh-like 20.511
Pou3f3POU domain, class 3, transcription factor 30.511
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.496
Pax2paired box gene 20.485
Smad6MAD homolog 6 (Drosophila)0.485
Foxc2forkhead box C20.480
Alx4aristaless-like homeobox 40.480
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.477
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.468
Tbx2T-box 20.451
Bcl2B-cell leukemia/lymphoma 20.446
Epha4Eph receptor A40.427
Dkk1dickkopf homolog 1 (Xenopus laevis)0.409
Per2period homolog 2 (Drosophila)0.404
Meox2mesenchyme homeobox 20.388
BaxBCL2-associated X protein0.385
Foxf1aforkhead box F1a0.368
Gata6GATA binding protein 60.367
Alx3aristaless-like homeobox 30.361
Sox9SRY-box containing gene 90.349
Bdnfbrain derived neurotrophic factor0.346
Rxraretinoid X receptor alpha0.344
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.322
Hey2hairy/enhancer-of-split related with YRPW motif 20.321
Tbx5T-box 50.306
Shesrc homology 2 domain-containing transforming protein E0.300
Jag1jagged 10.298
Twist2twist homolog 2 (Drosophila)0.287
Foxn1forkhead box N10.287
Wnt4wingless-related MMTV integration site 40.279
Fgf3fibroblast growth factor 30.277
Hes1hairy and enhancer of split 1 (Drosophila)0.274
Isl1ISL1 transcription factor, LIM/homeodomain0.271
Bmp7bone morphogenetic protein 70.264
Wnt3awingless-related MMTV integration site 3A0.260
Pax8paired box gene 80.258
Sox10SRY-box containing gene 100.257
Tcf21transcription factor 210.249
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.237
Wnt3wingless-related MMTV integration site 30.235
Gscgoosecoid homeobox0.233
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.229
Bmp5bone morphogenetic protein 50.219
Foxc1forkhead box C10.218
Pax7paired box gene 70.209
Gli1GLI-Kruppel family member GLI10.208
Nos3nitric oxide synthase 3, endothelial cell0.205
Chd7chromodomain helicase DNA binding protein 70.202
Tcfap2ctranscription factor AP-2, gamma0.199
Adra2badrenergic receptor, alpha 2b0.197
Hoxd11homeobox D110.196
Lrp2low density lipoprotein receptor-related protein 20.191
Tcf15transcription factor 150.190
Hoxa11homeobox A110.189
UncxUNC homeobox0.187
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.186
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.184
Emid2EMI domain containing 20.183
Snai1snail homolog 1 (Drosophila)0.178
Dll4delta-like 4 (Drosophila)0.176
Lmx1aLIM homeobox transcription factor 1 alpha0.175
Lhx1LIM homeobox protein 10.174
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.173
Foxh1forkhead box H10.172
Egfrepidermal growth factor receptor0.170
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.165
Tal1T-cell acute lymphocytic leukemia 10.162
Ryr2ryanodine receptor 2, cardiac0.158
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.158
Fgfr3fibroblast growth factor receptor 30.154
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fdft1farnesyl diphosphate farnesyl transferase 10.014
Idi1isopentenyl-diphosphate delta isomerase 10.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism